[go: up one dir, main page]

ES2057528T3 - Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen. - Google Patents

Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen.

Info

Publication number
ES2057528T3
ES2057528T3 ES90901567T ES90901567T ES2057528T3 ES 2057528 T3 ES2057528 T3 ES 2057528T3 ES 90901567 T ES90901567 T ES 90901567T ES 90901567 T ES90901567 T ES 90901567T ES 2057528 T3 ES2057528 T3 ES 2057528T3
Authority
ES
Spain
Prior art keywords
pdgf
medicinal products
preparation procedures
containing medicinal
procedures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90901567T
Other languages
English (en)
Inventor
Jurgen Hoppe
Herbert A Weich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2057528T3 publication Critical patent/ES2057528T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCESO PARA PRODUCIR PDGF-A TAMBIEN COMO PDGF-AA BIOLOGICAMENTE ACTIVO Y PDGF-AB.
ES90901567T 1989-01-12 1990-01-11 Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen. Expired - Lifetime ES2057528T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3900770A DE3900770A1 (de) 1989-01-12 1989-01-12 Verfahren zur herstellung von pdgf-a und pdgf-aa

Publications (1)

Publication Number Publication Date
ES2057528T3 true ES2057528T3 (es) 1994-10-16

Family

ID=6371968

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90901567T Expired - Lifetime ES2057528T3 (es) 1989-01-12 1990-01-11 Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen.

Country Status (6)

Country Link
EP (1) EP0453456B1 (es)
JP (1) JPH04504407A (es)
AU (1) AU4836790A (es)
DE (2) DE3900770A1 (es)
ES (1) ES2057528T3 (es)
WO (1) WO1990008163A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems
DE4228458A1 (de) * 1992-08-27 1994-06-01 Beiersdorf Ag Multicistronische Expressionseinheiten und deren Verwendung
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
PT948538E (pt) * 1996-12-13 2008-08-05 Novartis Vaccines & Diagnostic Análise e separação de proteínas do factor de crescimento derivado de plaquetas
AU1454199A (en) * 1997-11-07 1999-05-31 Massachusetts Institute Of Technology Pdgf-mediated microvascular communication and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801542A (en) * 1984-10-12 1989-01-31 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
EP0259632B1 (en) * 1986-08-13 1995-12-13 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
ES2091749T3 (es) * 1987-04-22 1996-11-16 Chiron Corp Produccion por recombinacion de polipeptidos de la cadena a del factor de crecimiento derivado de plaquetas (fcdp).
DE3725320A1 (de) * 1987-07-30 1989-02-09 Biotechnolog Forschung Gmbh Expressionsvektoren und verfahren unter deren verwendung zur gewinnung von cro/ss-galaktosidase/pth-fusionsproteinen und von pth

Also Published As

Publication number Publication date
DE59001317D1 (de) 1993-06-03
WO1990008163A1 (de) 1990-07-26
DE3900770A1 (de) 1990-07-26
AU4836790A (en) 1990-08-13
EP0453456B1 (de) 1993-04-28
EP0453456A1 (de) 1991-10-30
JPH04504407A (ja) 1992-08-06

Similar Documents

Publication Publication Date Title
ES2058151T3 (es) Complejos de saponinas con fosfolipidos y composiciones farmaceuticas y cosmeticas que los contienen.
MX27046A (es) 5-arilalquil-4-alcoxy-2(5h)-furanonas, productos intermedios y procedimiento para su preparacion asi como su aplicacion como sustancia activa terapeutica.
ES2058139T3 (es) Compuestos complejos de bioflavonoides con fosfolipidos, su preparacion y uso, y composiciones farmaceuticas y cosmeticas que los contienen.
ES2053719T3 (es) Dimetilvermectinas no naturales y procedimiento para su preparacion.
ES2138271T3 (es) Compuestos de 6-dimetil-amino-metil-1-fenil-ciclohexano como principio activo farmaceutico.
IL93098A0 (en) Alkylated polyethylenimine derivatives,process for their preparation and pharmaceutical preparations containing them
ES2075199T3 (es) Glicoproteina de origen humano; factor activo fisiologicamente que comprende la misma, y preparacion farmaceutica que contiene la misma como ingrediente activo.
ES2196082T3 (es) Analagos del factor de crecimiento de queratinocitos.
MX9308013A (es) 4-fenil-piridonas y 4-fenil-2-fenil-2-alcoxipiridinas sustituidas, procedimiento para su preparacion y medicamentos que los contienen.
AR008680A1 (es) Substitutos de plaquetas y metodos de conjugacion apropiados para su preparacion
ES2052603T3 (es) Derivados de bencimidazol, procedimiento para su produccion y composicion farmaceutica que los contienen.
ATE55695T1 (de) Verwendung von defibrotid zur herstellung pharmazeutischer zusammensetzungen zur behandlung peripherer arteriopathien.
IT7821336A0 (it) Pseudo-trissaccaridi, procedimenti per la loro preparazione e loro impiego come prodotti medicinali.
MX9302487A (es) Piridonas sustituidas por bifenilmetilo, procedimiento para su obtencion y medicamentos que las contienen.
ES2195040T3 (es) Conjugado que incluye un principio activo, un polipeptido y varios polieteres y su uso como medicamento.
ES471900A1 (es) Procedimiento para preparar oxialquilenos polimeros
MX9301746A (es) Nuevos acidos 9-fluor-7-oxo-7h-pirido(1,2,3,-de)(1,4)-benzoxacin-6-carboxilicos y sus esteres, procedimiento para su preparacion y medicamentos que los contienen.
ES2057528T3 (es) Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen.
ES2168845T3 (es) Composicion cosmetica que contiene un componente activo capaz de estimular "in vivo" la produccion de interleuquina 6 (il-6) por los queratinocitos humanos.
MX9301608A (es) Acidos 7-oxo-7h-pirido(1,2,3,de)(1,4)benzoxacin-6-carboxilico y sus esteres, procedimiento para su preparacion y medicamentos que los contienen.
ES2118726T3 (es) Factor de crecimiento epidermal como medicamento para la restauracion de neuronas de la substantia nigra en el tratamiento de trastornos neurodegenerativos.
DE2961935D1 (en) 4-nitro-2-trichloromethylphenyl disulfides, process for their preparation, means containing them as active ingredient and use against microorganisms
ES2077559T3 (es) Estabilizacion de proteinas terapeuticamente activas en preparados farmaceuticos.
MX9200288A (es) Procedimiento para la preparacion del acido 1,2,3,4-tetrahidroisoquinolin-3-carboxilico racemico y opticamente activo asi como sus productos previos.
MX9306420A (es) Piridonbifenilos sustituidos por alcoximetilo, procedimiento para su obtencion y medicamentos que los contienen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 453456

Country of ref document: ES