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ES2057137T3 - Procedimiento para preparar compuestos de oxazolina. - Google Patents

Procedimiento para preparar compuestos de oxazolina.

Info

Publication number
ES2057137T3
ES2057137T3 ES89309235T ES89309235T ES2057137T3 ES 2057137 T3 ES2057137 T3 ES 2057137T3 ES 89309235 T ES89309235 T ES 89309235T ES 89309235 T ES89309235 T ES 89309235T ES 2057137 T3 ES2057137 T3 ES 2057137T3
Authority
ES
Spain
Prior art keywords
procedure
oxazoline compounds
preparing oxazoline
preparing
alcohol solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89309235T
Other languages
English (en)
Inventor
Doris P Schumacher
Jon E Clark
Bruce L Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2057137T3 publication Critical patent/ES2057137T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/12—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

UN NUEVO PROCESO PARA PREPARAR COMPONENTES DE OXAZOLINA ESTA DISPUESTO. EL PROCESO UTILIZA UN ALCOHOL AMINO, UN COMPONENTE CIANO, UNA BASE Y UN DISOLVENTE ALCOHOL DIHIDRICO, OTRO POLIHIDRICO OMEZCLAS DE ELLOS.
ES89309235T 1988-09-14 1989-09-12 Procedimiento para preparar compuestos de oxazolina. Expired - Lifetime ES2057137T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24412688A 1988-09-14 1988-09-14

Publications (1)

Publication Number Publication Date
ES2057137T3 true ES2057137T3 (es) 1994-10-16

Family

ID=22921470

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89309235T Expired - Lifetime ES2057137T3 (es) 1988-09-14 1989-09-12 Procedimiento para preparar compuestos de oxazolina.

Country Status (12)

Country Link
EP (2) EP0434731A1 (es)
JP (1) JPH0670022B2 (es)
AT (1) ATE109775T1 (es)
CY (1) CY1834A (es)
DE (1) DE68917394T2 (es)
ES (1) ES2057137T3 (es)
FI (1) FI94635C (es)
HK (1) HK62295A (es)
HU (1) HU215919B (es)
NO (1) NO180633C (es)
SG (1) SG25995G (es)
WO (1) WO1990002738A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227494A (en) * 1988-09-14 1993-07-13 Schering Corporation Process for preparing oxazoline compounds
PL166385B1 (en) * 1990-10-25 1995-05-31 Schering Corp Method of obtaining oxazoline compound
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
CA2170661A1 (en) 1995-03-22 1996-09-23 John K. Thottathil Novel methods for the preparation of taxanes using oaxzolidine intermediates
US6228868B1 (en) 1998-07-27 2001-05-08 Abbott Laboratories Oxazoline antiproliferative agents
PL366100A1 (en) 2000-09-22 2005-01-24 Bristol-Myers Squibb Company Method for reducing toxicity of combined chemotherapies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2402198A (en) * 1944-09-06 1946-06-18 Du Pont Preparation of oxazolines
HU167760B (es) * 1972-10-20 1975-12-25
DE3310905A1 (de) * 1983-03-25 1984-09-27 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von 2-isopropenyloxazolinen

Also Published As

Publication number Publication date
EP0359516A1 (en) 1990-03-21
AU617542B2 (en) 1991-11-28
FI911237A0 (fi) 1991-03-13
AU4311489A (en) 1990-04-02
HU215919B (hu) 1999-03-29
JPH03504726A (ja) 1991-10-17
FI94635C (fi) 1995-10-10
HK62295A (en) 1995-05-05
SG25995G (en) 1995-08-18
ATE109775T1 (de) 1994-08-15
DE68917394D1 (de) 1994-09-15
NO180633C (no) 1997-05-21
EP0359516B1 (en) 1994-08-10
NO910911D0 (no) 1991-03-07
DE68917394T2 (de) 1994-12-01
JPH0670022B2 (ja) 1994-09-07
CY1834A (en) 1996-09-27
NO180633B (no) 1997-02-10
HUT56083A (en) 1991-07-29
NO910911L (no) 1991-03-07
FI94635B (fi) 1995-06-30
WO1990002738A1 (en) 1990-03-22
EP0434731A1 (en) 1991-07-03
HU895577D0 (en) 1991-06-28

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