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ES2057121T3 - Antagonistas de los receptores alfa-adrenergicos. - Google Patents

Antagonistas de los receptores alfa-adrenergicos.

Info

Publication number
ES2057121T3
ES2057121T3 ES89305340T ES89305340T ES2057121T3 ES 2057121 T3 ES2057121 T3 ES 2057121T3 ES 89305340 T ES89305340 T ES 89305340T ES 89305340 T ES89305340 T ES 89305340T ES 2057121 T3 ES2057121 T3 ES 2057121T3
Authority
ES
Spain
Prior art keywords
antagonists
alpha
adrenergic receptors
adrenoceptor
antagonism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89305340T
Other languages
English (en)
Inventor
John Joseph Lafferty
Robert Michael Demarinis
Dinubhai Himatlal Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2057121T3 publication Critical patent/ES2057121T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA INVENCION SE EFIERE A ANTAGONISTAS ALFA - ADRENORECEPTORES QUE TIENEN LA FORMULA(I), UTILES PARA PRODUCIR ANTAGONISMO ALFA ADRENORECEPTOR; A COMPOSICIONES FARMACEUTICAS QUE LOS INCLUYEN Y A METODOS PARA SU EMPLEO A FIN DE INDUCIR ANTAGONISMO ALFA ADRENORECEPTOR EN MAMIFEROS.
ES89305340T 1988-06-01 1989-05-26 Antagonistas de los receptores alfa-adrenergicos. Expired - Lifetime ES2057121T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20100588A 1988-06-01 1988-06-01

Publications (1)

Publication Number Publication Date
ES2057121T3 true ES2057121T3 (es) 1994-10-16

Family

ID=22744089

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89305340T Expired - Lifetime ES2057121T3 (es) 1988-06-01 1989-05-26 Antagonistas de los receptores alfa-adrenergicos.

Country Status (19)

Country Link
EP (1) EP0344981B1 (es)
JP (1) JP2846019B2 (es)
KR (1) KR900701796A (es)
CN (1) CN1029404C (es)
AT (1) ATE109483T1 (es)
AU (1) AU629221B2 (es)
CA (1) CA1320954C (es)
DE (1) DE68917217T2 (es)
DK (1) DK286090D0 (es)
ES (1) ES2057121T3 (es)
FI (1) FI905922A0 (es)
HU (1) HU208695B (es)
IE (1) IE66886B1 (es)
MY (1) MY106292A (es)
PH (1) PH25534A (es)
PT (1) PT90720B (es)
WO (1) WO1989012053A1 (es)
ZA (1) ZA894099B (es)
ZW (1) ZW6989A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2824106B1 (en) * 2012-03-06 2016-11-23 Takeda Pharmaceutical Company Limited Tricyclic compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856910A (en) * 1950-01-10 1974-12-24 Roussel Uclaf Novel thienobenzazepines as anti-depressants
US3649644A (en) * 1969-08-08 1972-03-14 Warner Lambert Co 1 2 3 4 4a 5 6 6a-octahydrobenzofuro (3 2-c)indoles
BE795451A (fr) * 1972-02-23 1973-08-16 Pfizer Agents hypoglycemiants aza indoliques tricycliques
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
JPS57144286A (en) * 1981-03-02 1982-09-06 Takeda Chem Ind Ltd Azepinoindole derivative and its preparation
US4833244A (en) * 1985-04-22 1989-05-23 Hoechst-Rouseel Pharmaceuticals Inc. Ethanobenzazepines
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4769368A (en) * 1986-02-10 1988-09-06 Smithkline Beckman Corporation 2,3,4,8,9,9A-Hexahydro-4-aryl-1H-indeno(1,7-CD)azepines
DE3630539A1 (de) * 1986-09-08 1988-03-10 Madaus & Co Dr Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten

Also Published As

Publication number Publication date
HUT58742A (en) 1992-03-30
EP0344981A2 (en) 1989-12-06
PT90720A (pt) 1989-12-29
DK286090A (da) 1990-11-30
PT90720B (pt) 1994-10-31
AU3741589A (en) 1990-01-05
WO1989012053A1 (en) 1989-12-14
CA1320954C (en) 1993-08-03
MY106292A (en) 1995-04-29
DK286090D0 (da) 1990-11-30
JP2846019B2 (ja) 1999-01-13
PH25534A (en) 1991-07-24
DE68917217D1 (de) 1994-09-08
JPH03504604A (ja) 1991-10-09
CN1029404C (zh) 1995-08-02
EP0344981B1 (en) 1994-08-03
KR900701796A (ko) 1990-12-04
ZA894099B (en) 1990-06-27
CN1038100A (zh) 1989-12-20
EP0344981A3 (en) 1991-05-15
IE891740L (en) 1989-12-01
DE68917217T2 (de) 1994-12-01
ATE109483T1 (de) 1994-08-15
HU208695B (en) 1993-12-28
HU893309D0 (en) 1991-05-28
AU629221B2 (en) 1992-10-01
FI905922A0 (fi) 1990-11-30
ZW6989A1 (en) 1989-08-30
IE66886B1 (en) 1996-02-07

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