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ES2056333T3 - (quinolin-2-il-metoxi)fenil-carbonil-ureas substituidas. - Google Patents

(quinolin-2-il-metoxi)fenil-carbonil-ureas substituidas.

Info

Publication number
ES2056333T3
ES2056333T3 ES90119551T ES90119551T ES2056333T3 ES 2056333 T3 ES2056333 T3 ES 2056333T3 ES 90119551 T ES90119551 T ES 90119551T ES 90119551 T ES90119551 T ES 90119551T ES 2056333 T3 ES2056333 T3 ES 2056333T3
Authority
ES
Spain
Prior art keywords
quinolin
metoxi
ureas
carbonyl
substituted phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90119551T
Other languages
English (en)
Inventor
Siegfried Dr Raddatz
Klaus Dr Mohrs
Burkhard Dr Fugmann
Romanis Fruchtmann
Christian Dr Kohlsdorfer
Reiner Prof Muller-Peddinghaus
Pia Dr Theissen-Popp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2056333T3 publication Critical patent/ES2056333T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PUEDEN OBTENER UREAS DE (QUINOLIN-2-IL-METOXI)FENIL-CARBONILO SUSTITUIDAS MEDIANTE REACCION DE ANILINAS DE (QUINOLIN-2-IL-METOXI) CON ISOCIANATOS Y, DADO EL CASO, UNA POSTERIOR ALCOHOLIZACION. ESTE PRODUCTO PUEDE SER APLICADO COMO SUSTANCIA ACTIVA DE MEDICAMENTOS, ESPECIALMENTE PARA LA INHIBICION DE REACCIONES ENZIMATICAS EN EL MARCO DEL METABOLISMO DEL ACIDO ARAQUIDONICO.
ES90119551T 1989-10-25 1990-10-12 (quinolin-2-il-metoxi)fenil-carbonil-ureas substituidas. Expired - Lifetime ES2056333T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3935491A DE3935491A1 (de) 1989-10-25 1989-10-25 Substituierte (chinolin-2-yl-methoxy)phenyl-carbonylharnstoffe

Publications (1)

Publication Number Publication Date
ES2056333T3 true ES2056333T3 (es) 1994-10-01

Family

ID=6392154

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90119551T Expired - Lifetime ES2056333T3 (es) 1989-10-25 1990-10-12 (quinolin-2-il-metoxi)fenil-carbonil-ureas substituidas.

Country Status (7)

Country Link
EP (1) EP0428860B1 (es)
JP (1) JPH03145467A (es)
AT (1) ATE108181T1 (es)
CA (1) CA2028314A1 (es)
DE (2) DE3935491A1 (es)
DK (1) DK0428860T3 (es)
ES (1) ES2056333T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4139750A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Chinolylmethoxyphenylessigsaeure-acylamide und -harnstoffe
TW232013B (es) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
US5455252A (en) * 1993-03-31 1995-10-03 Syntex (U.S.A.) Inc. Optionally substituted 6,8-quinolines
US5475003A (en) * 1994-03-03 1995-12-12 Syntex (U.S.A.) Inc. 8-phenylcyclopentenoquinoline and 8-phenylcyclohexenoquinoline derivatives
SV2005001973A (es) 2003-12-12 2005-11-04 Wyeth Corp Quinolinas utiles en el tratamiento de enfermedades cardiovasculares ref. wyth0090-504 (am101500)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5764675A (en) * 1980-10-07 1982-04-19 Nissan Chem Ind Ltd Substituted phenylurea derivative, its preparation, and selective herbicide containing said compound
EP0309541B1 (en) * 1987-03-18 1992-01-02 American Home Products Corporation Sulfonylcarboxamides

Also Published As

Publication number Publication date
ATE108181T1 (de) 1994-07-15
DK0428860T3 (da) 1994-10-17
EP0428860A3 (en) 1991-10-09
JPH03145467A (ja) 1991-06-20
DE59006363D1 (de) 1994-08-11
CA2028314A1 (en) 1991-04-26
EP0428860A2 (de) 1991-05-29
EP0428860B1 (de) 1994-07-06
DE3935491A1 (de) 1991-05-02

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