ES2056207T3 - Alcoholes aromaticos tio-sustituidos, preparacion, intermedios y uso. - Google Patents
Alcoholes aromaticos tio-sustituidos, preparacion, intermedios y uso.Info
- Publication number
- ES2056207T3 ES2056207T3 ES89302838T ES89302838T ES2056207T3 ES 2056207 T3 ES2056207 T3 ES 2056207T3 ES 89302838 T ES89302838 T ES 89302838T ES 89302838 T ES89302838 T ES 89302838T ES 2056207 T3 ES2056207 T3 ES 2056207T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- optionally protected
- substituted
- formula
- thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/12—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
- C07C321/20—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Abstract
COMPUESTOS FARMACEUTICOS DE LA FORMULA(I) EN LA QUE R1 ES ALQUILO HALO - SUSTITUIDO; X ES ALQUENILENO; Y R`- Y CONTIENE 6 S 34 C; R2 ES C1 - 5 ALQUIL SUSTITUIDO POR I) CARBOXILO OPCIONALMENTE PROTEGIDO, TETRAZOLILO O - CONR`R" OPCIONALMENTE PROTEGIDO CON NITRILO, EN DONDE R`Y R" SON H O C1 - 4 ALQUILO, II) FORMULA(II), EN DONDE R`Y R" SON H O C1 - C4 ALQUILO O III) FORMULA(III) DONDE E`,R" Y R``` SON H O C1 - 4 ALQUILO, O R2 ES UN GRUPO DE LA FORMULA(IV) EN DONDE R`ES H O UN RESIDUO DE AMINOACIDO PROTEGIDO OPCIONALMENTE; Y R3, R4 Y R5 SON H, CARBOXILO PROTEGIDO OPCIONALMENTE, C1 - 4 ALQUILO, C1 - 4 ALCOXI, HIDROXILO, TETRAZOLILO OPCIONALMENTE PROTEGIDO, HALO, TRIFLUOROMETILO, NITRILO, NITRO O - CONR`R" DONDE R`Y R" SON H O C1 - 4 ALQUILO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888807016A GB8807016D0 (en) | 1988-03-24 | 1988-03-24 | Organic compounds & their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2056207T3 true ES2056207T3 (es) | 1994-10-01 |
Family
ID=10634031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89302838T Expired - Lifetime ES2056207T3 (es) | 1988-03-24 | 1989-03-22 | Alcoholes aromaticos tio-sustituidos, preparacion, intermedios y uso. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5021441A (es) |
| EP (1) | EP0343777B1 (es) |
| JP (1) | JPH024769A (es) |
| KR (1) | KR890014568A (es) |
| CN (1) | CN1036568A (es) |
| AR (1) | AR246517A1 (es) |
| AT (1) | ATE107292T1 (es) |
| AU (1) | AU615994B2 (es) |
| DE (1) | DE68916110T2 (es) |
| DK (1) | DK146689A (es) |
| ES (1) | ES2056207T3 (es) |
| GB (1) | GB8807016D0 (es) |
| HU (1) | HU203530B (es) |
| IE (1) | IE63218B1 (es) |
| IL (1) | IL89665A0 (es) |
| MX (1) | MX15390A (es) |
| NZ (1) | NZ228460A (es) |
| PH (1) | PH27529A (es) |
| PT (1) | PT90059B (es) |
| ZA (1) | ZA892224B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8709546D0 (en) * | 1987-04-22 | 1987-05-28 | Lilly Industries Ltd | Pharmaceutical use of organic compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| DE3469169D1 (en) * | 1983-04-21 | 1988-03-10 | Merck Frosst Canada Inc | Leukotriene antagonists, their production and use and compositions containing them |
| GB8320943D0 (en) * | 1983-08-03 | 1983-09-07 | Lilly Industries Ltd | Organic compounds |
| GB8432144D0 (en) * | 1984-12-20 | 1985-01-30 | Lilly Industries Ltd | Organic compounds |
| GB8502258D0 (en) * | 1985-01-30 | 1985-02-27 | Lilly Industries Ltd | Organic compounds |
| GB8530222D0 (en) * | 1985-12-07 | 1986-01-15 | Lilly Industries Ltd | Organic compounds |
| US4785004A (en) * | 1985-12-23 | 1988-11-15 | Ciba-Geigy Corporation | Aromatic thioethers |
| GB8709546D0 (en) * | 1987-04-22 | 1987-05-28 | Lilly Industries Ltd | Pharmaceutical use of organic compounds |
| GB8709547D0 (en) * | 1987-04-22 | 1987-05-28 | Lilly Industries Ltd | Organic compounds |
-
1988
- 1988-03-24 GB GB888807016A patent/GB8807016D0/en active Pending
-
1989
- 1989-03-20 IL IL89665A patent/IL89665A0/xx unknown
- 1989-03-21 PT PT90059A patent/PT90059B/pt not_active IP Right Cessation
- 1989-03-22 DK DK146689A patent/DK146689A/da not_active Application Discontinuation
- 1989-03-22 DE DE68916110T patent/DE68916110T2/de not_active Expired - Fee Related
- 1989-03-22 EP EP89302838A patent/EP0343777B1/en not_active Expired - Lifetime
- 1989-03-22 PH PH38368A patent/PH27529A/en unknown
- 1989-03-22 AU AU31598/89A patent/AU615994B2/en not_active Ceased
- 1989-03-22 ES ES89302838T patent/ES2056207T3/es not_active Expired - Lifetime
- 1989-03-22 AR AR89313476A patent/AR246517A1/es active
- 1989-03-22 MX MX1539089A patent/MX15390A/es unknown
- 1989-03-22 US US07/326,939 patent/US5021441A/en not_active Expired - Fee Related
- 1989-03-22 AT AT89302838T patent/ATE107292T1/de not_active IP Right Cessation
- 1989-03-22 NZ NZ228460A patent/NZ228460A/en unknown
- 1989-03-23 ZA ZA892224A patent/ZA892224B/xx unknown
- 1989-03-23 JP JP1071590A patent/JPH024769A/ja active Pending
- 1989-03-23 HU HU891413A patent/HU203530B/hu not_active IP Right Cessation
- 1989-03-23 IE IE93989A patent/IE63218B1/en not_active IP Right Cessation
- 1989-03-23 CN CN89101775A patent/CN1036568A/zh active Pending
- 1989-03-23 KR KR1019890003641A patent/KR890014568A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PH27529A (en) | 1993-08-18 |
| ATE107292T1 (de) | 1994-07-15 |
| GB8807016D0 (en) | 1988-04-27 |
| DE68916110D1 (de) | 1994-07-21 |
| PT90059A (pt) | 1989-11-10 |
| KR890014568A (ko) | 1989-10-24 |
| JPH024769A (ja) | 1990-01-09 |
| AU3159889A (en) | 1989-09-28 |
| IE63218B1 (en) | 1995-04-05 |
| NZ228460A (en) | 1991-03-26 |
| EP0343777A1 (en) | 1989-11-29 |
| US5021441A (en) | 1991-06-04 |
| DK146689A (da) | 1989-09-25 |
| PT90059B (pt) | 1994-05-31 |
| ZA892224B (en) | 1990-11-28 |
| DE68916110T2 (de) | 1994-09-22 |
| CN1036568A (zh) | 1989-10-25 |
| AR246517A1 (es) | 1994-08-31 |
| IE890939L (en) | 1989-09-24 |
| IL89665A0 (en) | 1989-09-28 |
| MX15390A (es) | 1993-10-01 |
| HUT50458A (en) | 1990-02-28 |
| AU615994B2 (en) | 1991-10-17 |
| DK146689D0 (da) | 1989-03-22 |
| HU203530B (en) | 1991-08-28 |
| EP0343777B1 (en) | 1994-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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