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ES2052837T3 - Derivados marcados radioactivamente de la benzodiazepina. - Google Patents

Derivados marcados radioactivamente de la benzodiazepina.

Info

Publication number
ES2052837T3
ES2052837T3 ES89114359T ES89114359T ES2052837T3 ES 2052837 T3 ES2052837 T3 ES 2052837T3 ES 89114359 T ES89114359 T ES 89114359T ES 89114359 T ES89114359 T ES 89114359T ES 2052837 T3 ES2052837 T3 ES 2052837T3
Authority
ES
Spain
Prior art keywords
benzodiazepine
labeled derivatives
radioactive labeled
derivatives
radioactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89114359T
Other languages
English (en)
Inventor
Heinz Dr Carmann
Walter Dr Hunkeler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2052837T3 publication Critical patent/ES2052837T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K51/047—Benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Particle Accelerators (AREA)
  • Lubricants (AREA)
  • Vessels And Coating Films For Discharge Lamps (AREA)

Abstract

SE DESCRIBEN DERIVADOS RADIOYODADOS 5,6-DIHIDRO-5-METILO-6-OXO-4H-INIDAZO [1,5-A][1,4] BENZODIACEPIN Y SU USO COMO MEDIOS REPRESENTANTES FRONTALES.
ES89114359T 1988-08-05 1989-08-03 Derivados marcados radioactivamente de la benzodiazepina. Expired - Lifetime ES2052837T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22906488A 1988-08-05 1988-08-05

Publications (1)

Publication Number Publication Date
ES2052837T3 true ES2052837T3 (es) 1994-07-16

Family

ID=22859710

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89114359T Expired - Lifetime ES2052837T3 (es) 1988-08-05 1989-08-03 Derivados marcados radioactivamente de la benzodiazepina.

Country Status (12)

Country Link
EP (1) EP0353754B1 (es)
JP (1) JPH0733387B2 (es)
KR (1) KR930001406B1 (es)
AT (1) ATE82851T1 (es)
AU (1) AU622206B2 (es)
CA (1) CA1318668C (es)
DE (1) DE58902867D1 (es)
DK (1) DK381989A (es)
ES (1) ES2052837T3 (es)
HK (1) HK127694A (es)
NZ (1) NZ230193A (es)
PH (1) PH26382A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101305B1 (fi) * 1996-03-18 1998-05-29 Map Medical Technologies Oy Radiofarmaseuttisena aineena käyttökelpoiset radiojodatut bentsodiatsepiini-johdannaiset ja niiden käyttö diagnostiikassa
JP4637096B2 (ja) * 2004-03-25 2011-02-23 日本メジフィジックス株式会社 放射性組成物及び放射性組成物の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
CA1174673A (en) * 1981-02-27 1984-09-18 Walter Hunkeler Imidazodiazepines
US4352817A (en) * 1981-02-27 1982-10-05 Hoffmann-La Roche Inc. Imidazo-diazepines and their use
CA1184175A (en) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
US4777169A (en) * 1987-07-24 1988-10-11 Hoffmann-La Roche Inc. Benzodiazepine derivatives
JPH0780858B2 (ja) * 1987-10-19 1995-08-30 住友化学工業株式会社 放射性ベンゾジアゼピン誘導体およびその製造法

Also Published As

Publication number Publication date
EP0353754A3 (en) 1990-04-11
NZ230193A (en) 1992-01-29
DK381989A (da) 1990-02-06
DE58902867D1 (de) 1993-01-14
AU3934289A (en) 1990-02-08
CA1318668C (en) 1993-06-01
DK381989D0 (da) 1989-08-03
ATE82851T1 (de) 1992-12-15
KR900003171A (ko) 1990-03-23
JPH0733387B2 (ja) 1995-04-12
EP0353754B1 (de) 1992-12-02
KR930001406B1 (ko) 1993-02-27
PH26382A (en) 1992-06-01
JPH0269479A (ja) 1990-03-08
HK127694A (en) 1994-11-25
EP0353754A2 (de) 1990-02-07
AU622206B2 (en) 1992-04-02

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