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ES2052621T3 - Procedimiento para la preparacion de plasma deficiente en factor viii:c, y un plasma deficiente, asi obtenido. - Google Patents

Procedimiento para la preparacion de plasma deficiente en factor viii:c, y un plasma deficiente, asi obtenido.

Info

Publication number
ES2052621T3
ES2052621T3 ES88103137T ES88103137T ES2052621T3 ES 2052621 T3 ES2052621 T3 ES 2052621T3 ES 88103137 T ES88103137 T ES 88103137T ES 88103137 T ES88103137 T ES 88103137T ES 2052621 T3 ES2052621 T3 ES 2052621T3
Authority
ES
Spain
Prior art keywords
deficient plasma
factor viii
preparation
procedure
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88103137T
Other languages
English (en)
Inventor
Udo Dr Becker
Norbert Prof Dr Heimburger
Konrad Braun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2052621T3 publication Critical patent/ES2052621T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE DESCRIBEN UN PROCEDIMIENTO PARA LA OBTENCION DE UN PLASMA DEFICITARIO EN FACTOR VIII:C EN EL QUE UN PLASMA DE PARTIDA SE TRATA CONSECUTIVAMENTE CON ANTICUERPOS CONTRA EL FACTOR DE WILLEBRAND Y ANTICUERPOS CONTRA EL FACTOR VIII:C:AG. EL PLASMA DEFICITARIO OBTENIDO POR ESTE METODO CONTIENE UNA ACTIVIDAD RESIDUAL DE FACTOR VIII:C INFERIOR AL 0,5%.
ES88103137T 1987-03-06 1988-03-02 Procedimiento para la preparacion de plasma deficiente en factor viii:c, y un plasma deficiente, asi obtenido. Expired - Lifetime ES2052621T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873707213 DE3707213A1 (de) 1987-03-06 1987-03-06 Verfahren zur herstellung von faktor viii:c-mangelplasma und ein so erhaltenes mangelplasma

Publications (1)

Publication Number Publication Date
ES2052621T3 true ES2052621T3 (es) 1994-07-16

Family

ID=6322416

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88103137T Expired - Lifetime ES2052621T3 (es) 1987-03-06 1988-03-02 Procedimiento para la preparacion de plasma deficiente en factor viii:c, y un plasma deficiente, asi obtenido.

Country Status (8)

Country Link
US (1) US5021243A (es)
EP (1) EP0281089B1 (es)
JP (1) JP2672961B2 (es)
AT (1) ATE81013T1 (es)
AU (1) AU620799B2 (es)
CA (1) CA1312278C (es)
DE (2) DE3707213A1 (es)
ES (1) ES2052621T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
DE3904354A1 (de) * 1989-02-14 1990-08-16 Behringwerke Ag Pasteurisiertes, gereinigtes von willebrand-faktor-konzentrat und verfahren zu seiner herstellung
DE4014665C2 (de) * 1990-05-08 1994-06-01 Sanol Arznei Schwarz Gmbh Oberflächenvergütete Gläser in Primärpackmitteln von Lyophilisaten und deren Verwendung bei der Herstellung von Lyophilisaten
AT403765B (de) 1996-04-12 1998-05-25 Immuno Ag Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
DE19634312A1 (de) 1996-08-24 1998-02-26 Behringwerke Ag Verfahren zur Herstellung von Faktor V-Mangelplasma und ein so erhaltenes Mangelplasma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4716117A (en) * 1984-10-26 1987-12-29 Chiron Corporation Monoclonal antibodies to factor VIIIC
FR2570276B1 (fr) * 1984-09-18 1987-09-04 Immunotech Sa Procede d'obtention du complexe fviii/vwf a usage therapeutique et produits en resultant
JPH01147367A (ja) * 1987-12-03 1989-06-09 Dai Ichi Pure Chem Co Ltd 凝血因子の測定方法及び測定用試薬

Also Published As

Publication number Publication date
EP0281089A3 (en) 1989-08-02
ATE81013T1 (de) 1992-10-15
US5021243A (en) 1991-06-04
DE3707213A1 (de) 1988-09-15
EP0281089B1 (de) 1992-09-30
AU1264688A (en) 1988-09-08
JP2672961B2 (ja) 1997-11-05
DE3874914D1 (de) 1992-11-05
EP0281089A2 (de) 1988-09-07
JPS63235867A (ja) 1988-09-30
AU620799B2 (en) 1992-02-27
CA1312278C (en) 1993-01-05

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