ES2051864T3 - Un procedimiento para preparar una composicion farmaceutica con actividad anti-cancer. - Google Patents
Un procedimiento para preparar una composicion farmaceutica con actividad anti-cancer.Info
- Publication number
- ES2051864T3 ES2051864T3 ES88310908T ES88310908T ES2051864T3 ES 2051864 T3 ES2051864 T3 ES 2051864T3 ES 88310908 T ES88310908 T ES 88310908T ES 88310908 T ES88310908 T ES 88310908T ES 2051864 T3 ES2051864 T3 ES 2051864T3
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- procedure
- pharmaceutical composition
- cancer activity
- benzylidene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001093 anti-cancer Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- SWTGJCNCBUCXSS-ISUZDFFFSA-N (2r)-3,4-dihydroxy-2-[(4s)-2-phenyl-1,3-dioxolan-4-yl]-2h-furan-5-one Chemical compound OC1=C(O)C(=O)O[C@@H]1[C@H]1OC(C=2C=CC=CC=2)OC1 SWTGJCNCBUCXSS-ISUZDFFFSA-N 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002211 L-ascorbic acid Substances 0.000 abstract 1
- 235000000069 L-ascorbic acid Nutrition 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003172 aldehyde group Chemical group 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000003013 cytotoxicity Effects 0.000 abstract 1
- 231100000135 cytotoxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Abstract
EL USO DE ACIDO L-ASCORBICO, O DE UNA SAL FARMACEUTICAMENTE ACEPTABLE DE EL, EN COMBINACION CON ACIDO 5,6-O-BENCILIDENO-LASCORBICO CON DEUTERIO AL MENOS EN LA POSICION 1 ALDEHIDO DE LA MITAD DEL BENCILIDENO, O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE TALES ACIDOS, PRODUCE UNA CITOTOXICIDAD SINERGISTICAMENTE MEJORADA SOBRE LAS CELULAS DE CANCER HUMANO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88310908A EP0369079B1 (en) | 1988-11-18 | 1988-11-18 | Pharmaceutical compositions with anti-cancer activity and method for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2051864T3 true ES2051864T3 (es) | 1994-07-01 |
Family
ID=8200292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88310908T Expired - Lifetime ES2051864T3 (es) | 1988-11-18 | 1988-11-18 | Un procedimiento para preparar una composicion farmaceutica con actividad anti-cancer. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0369079B1 (es) |
AT (1) | ATE79750T1 (es) |
DE (1) | DE3874142T2 (es) |
ES (1) | ES2051864T3 (es) |
GB (1) | GB2208798B (es) |
GR (1) | GR3005531T3 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4427690A1 (de) * | 1994-08-04 | 1996-02-08 | Bogdahn Ulrich Prof | Deuterium enthaltende pharmazeutische Zusammensetzung als Zytostatikum oder Tumor-Therapeutikum |
DE19603477A1 (de) * | 1996-01-31 | 1997-08-07 | Klaus Dr Med Reuter | Tumormittel |
ATE401071T1 (de) * | 1999-08-30 | 2008-08-15 | Ester C Company | Verwendungen und zusammensetzungen für selektive krebs-chemotherapie |
EP4129283A4 (en) * | 2020-03-31 | 2024-04-24 | Natural Medicine Institute of Zhejiang Yangshengtang Co., Ltd. | PHARMACEUTICAL ASSOCIATION AND ITS USE |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60139619A (ja) * | 1983-12-27 | 1985-07-24 | Mutsuyuki Kochi | O−ベンジリデン−アスコルビン酸又はその塩よりなる抗腫瘍剤 |
EP0249632A4 (en) * | 1985-12-05 | 1988-06-20 | American Biotechnology | ATHRACYCLINE TYPE OF ANTITUARY WITH L-ASCORBIC ACID. |
-
1987
- 1987-07-20 GB GB8719670A patent/GB2208798B/en not_active Expired - Lifetime
-
1988
- 1988-11-18 AT AT88310908T patent/ATE79750T1/de not_active IP Right Cessation
- 1988-11-18 EP EP88310908A patent/EP0369079B1/en not_active Expired
- 1988-11-18 DE DE8888310908T patent/DE3874142T2/de not_active Expired - Fee Related
- 1988-11-18 ES ES88310908T patent/ES2051864T3/es not_active Expired - Lifetime
-
1992
- 1992-08-27 GR GR920401813T patent/GR3005531T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE79750T1 (de) | 1992-09-15 |
DE3874142D1 (de) | 1992-10-01 |
DE3874142T2 (de) | 1993-01-14 |
GB2208798A (en) | 1989-04-19 |
EP0369079B1 (en) | 1992-08-26 |
GR3005531T3 (es) | 1993-06-07 |
EP0369079A1 (en) | 1990-05-23 |
GB2208798B (en) | 1991-06-05 |
GB8719670D0 (en) | 1987-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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