ES2044091T3 - Formulaciones anti-neoplasticas. - Google Patents
Formulaciones anti-neoplasticas.Info
- Publication number
- ES2044091T3 ES2044091T3 ES89302599T ES89302599T ES2044091T3 ES 2044091 T3 ES2044091 T3 ES 2044091T3 ES 89302599 T ES89302599 T ES 89302599T ES 89302599 T ES89302599 T ES 89302599T ES 2044091 T3 ES2044091 T3 ES 2044091T3
- Authority
- ES
- Spain
- Prior art keywords
- carboplatin
- solution
- lyophilisate
- reconstituting
- neoplastic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000118 anti-neoplastic effect Effects 0.000 title 1
- 229940034982 antineoplastic agent Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 190000008236 Carboplatin Chemical compound 0.000 abstract 4
- 229960004562 carboplatin Drugs 0.000 abstract 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
EL CARBOPLATINO SE PRODUCE CONVENCIONALMENTE EN SOLUCIONES INYECTABLES EXTEMPORANEAS POR RECONSTITUCION DE UN LIOFILIZADO CON AGUA O UNA SOLUCION DE DEXTROSA O SALINA. ESTO ES DIFICIL Y PELIGROSO Y LAS SOLUCIONES FORMADAS SON INESTABLES. LA INVENCION PROPORCIONA UNA SOLUCION ACUOSA, INYECTABLE DE CARBOPLATINO, ESTABLE Y LISTA PARA USAR HECHA SIN RECONSTRUIR UN LIOFILIZADO, ES DECIR, A PARTIR DE CARBOPLATINO NO LIOFILIZADO. LA SOLUCION PREFERIBLEMENTE CONTIENE DE 10 A 15 MG/ML DE CARBOPLATINO, UN POLIOL (HASTA 10% DE MANITOL) Y UN CONSERVANTE, PERO ESTA EXENTA DE SAL Y TIENE PREFERIBLEMENTE UN PH ENTRE 5 Y 7.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL85790A IL85790A0 (en) | 1988-03-20 | 1988-03-20 | Solution of carboplatin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2044091T3 true ES2044091T3 (es) | 1994-01-01 |
Family
ID=11058683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89302599T Expired - Lifetime ES2044091T3 (es) | 1988-03-20 | 1989-03-16 | Formulaciones anti-neoplasticas. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0334551B1 (es) |
| AT (1) | ATE80296T1 (es) |
| AU (1) | AU623632B2 (es) |
| DE (1) | DE68902755T2 (es) |
| ES (1) | ES2044091T3 (es) |
| IL (1) | IL85790A0 (es) |
| ZA (1) | ZA891360B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455270A (en) * | 1993-08-11 | 1995-10-03 | Bristol-Myers Squibb Co. | Stabilized solutions of platinum(II) antitumor agents |
| ES2160117T3 (es) * | 1994-02-07 | 2001-11-01 | Pliva Pharmaceutical Industry | Composicion farmaceutica antitumoral a base de carboplatino, y su procedimiento de produccion. |
| EP3826613B1 (en) * | 2018-08-31 | 2024-11-20 | Sun Pharmaceutical Industries Limited | Parenteral dosage form of carboplatin |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1119954A (en) * | 1978-05-30 | 1982-03-16 | Edmund S. Granatek | Aqueous solution of cisplatin |
| US4571335A (en) * | 1983-06-17 | 1986-02-18 | Taylor Robert C | Method of inhibiting herpetic lesions by the use of platinum coordination compounds |
-
1988
- 1988-03-20 IL IL85790A patent/IL85790A0/xx unknown
-
1989
- 1989-02-22 ZA ZA891360A patent/ZA891360B/xx unknown
- 1989-02-23 AU AU30265/89A patent/AU623632B2/en not_active Withdrawn - After Issue
- 1989-03-16 AT AT89302599T patent/ATE80296T1/de not_active IP Right Cessation
- 1989-03-16 EP EP89302599A patent/EP0334551B1/en not_active Expired - Lifetime
- 1989-03-16 ES ES89302599T patent/ES2044091T3/es not_active Expired - Lifetime
- 1989-03-16 DE DE8989302599T patent/DE68902755T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE68902755T2 (de) | 1993-01-14 |
| DE68902755D1 (de) | 1992-10-15 |
| AU3026589A (en) | 1989-09-21 |
| AU623632B2 (en) | 1992-05-21 |
| ATE80296T1 (de) | 1992-09-15 |
| ZA891360B (en) | 1989-12-27 |
| IL85790A0 (en) | 1988-09-30 |
| EP0334551B1 (en) | 1992-09-09 |
| EP0334551A1 (en) | 1989-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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