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ES2017098B3 - Procedimiento para la preparacion de una disolucion farmaceutica acuosa de un principio activo constituido por un acido organico. - Google Patents

Procedimiento para la preparacion de una disolucion farmaceutica acuosa de un principio activo constituido por un acido organico.

Info

Publication number
ES2017098B3
ES2017098B3 ES87400964T ES87400964T ES2017098B3 ES 2017098 B3 ES2017098 B3 ES 2017098B3 ES 87400964 T ES87400964 T ES 87400964T ES 87400964 T ES87400964 T ES 87400964T ES 2017098 B3 ES2017098 B3 ES 2017098B3
Authority
ES
Spain
Prior art keywords
procedure
preparation
organic acid
active substance
pharmaceutical solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87400964T
Other languages
English (en)
Inventor
Florence Maurin
Claude Coquelet
Alain Tournoux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Chauvin SAS
Original Assignee
Laboratoires Chauvin SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Chauvin SAS filed Critical Laboratoires Chauvin SAS
Application granted granted Critical
Publication of ES2017098B3 publication Critical patent/ES2017098B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES87400964T 1986-04-30 1987-04-24 Procedimiento para la preparacion de una disolucion farmaceutica acuosa de un principio activo constituido por un acido organico. Expired - Lifetime ES2017098B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8606346A FR2598081B1 (fr) 1986-04-30 1986-04-30 Procede de preparation d'une solution pharmaceutique aqueuse d'un principe actif constitue par un acide organique

Publications (1)

Publication Number Publication Date
ES2017098B3 true ES2017098B3 (es) 1991-01-01

Family

ID=9334832

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87400964T Expired - Lifetime ES2017098B3 (es) 1986-04-30 1987-04-24 Procedimiento para la preparacion de una disolucion farmaceutica acuosa de un principio activo constituido por un acido organico.

Country Status (8)

Country Link
US (1) US4866088A (es)
EP (1) EP0244315B1 (es)
JP (1) JPH0749373B2 (es)
AT (1) ATE56139T1 (es)
DE (1) DE3764700D1 (es)
ES (1) ES2017098B3 (es)
FR (1) FR2598081B1 (es)
GR (1) GR3000838T3 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2012532A6 (es) * 1988-07-15 1990-04-01 Cusi Lab Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica.
JPH0248526A (ja) * 1988-08-08 1990-02-19 Sumitomo Pharmaceut Co Ltd インドメタシン注射剤およびその製造方法
ES2038580T3 (es) * 1989-08-03 1994-10-16 Eisai Co Ltd Metodo de fotoestabilizacion de soluciones oftalmicas.
CA2021441A1 (en) * 1989-08-18 1991-02-19 Alberto Ferro Process for the manufacture of parenteral application formulations
FR2670675B1 (fr) * 1990-12-20 1993-04-16 Lafon Labor Procede de preparation de formes pharmaceutiques stables a base d'acide acetylsalicylique ou de ses sels.
TW274516B (es) * 1993-11-12 1996-04-21 Ciba Geigy Ag
MX9703988A (es) * 1994-12-12 1998-02-28 Omeros Med Sys Inc SOLUCIaN Y MÉTODO DE IRRIGACIaN PARA LA INHIBICIaN DEL DOLOR, LA INFLAMACIaN Y ES ESPASMO.
AU4467396A (en) * 1994-12-12 1996-07-10 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
FR2738149B1 (fr) * 1995-09-06 1997-11-14 Chauvin Lab Sa Collyre a base d'indometacine pret a l'emploi
US5744154A (en) * 1995-09-06 1998-04-28 Laboratoire Chauvin S.A. Ready-to-use indomethacin-based eye lotion
US20030191187A1 (en) * 2002-04-01 2003-10-09 Lee Fang Yu Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same
US20090136505A1 (en) * 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
JP5276591B2 (ja) * 2007-08-09 2013-08-28 千寿製薬株式会社 ピレノキシン含有二液性点眼剤
CA2706709C (en) * 2007-11-30 2015-06-16 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3193459A (en) * 1955-07-01 1965-07-06 Upjohn Co Steroid hemisuccinate compositions and method for extemporaneous administration
ES415972A1 (es) * 1973-06-15 1974-04-01 Inst Llorente S A Procedimiento para la preparacion de soluciones inyectablesde complejos de indicacion antineuritica, de vitaminas, co- fermentos, y sus asociaciones.
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
US4443432A (en) * 1981-10-05 1984-04-17 Alcon Laboratories, Inc. Ophthmalic irrigating solution
JPS58152811A (ja) * 1982-03-08 1983-09-10 Sumitomo Chem Co Ltd インドメタシン点眼組成物
JPS60184013A (ja) * 1984-03-01 1985-09-19 Yoshitomi Pharmaceut Ind Ltd 点眼剤

Also Published As

Publication number Publication date
EP0244315A1 (fr) 1987-11-04
FR2598081B1 (fr) 1990-02-02
JPH0749373B2 (ja) 1995-05-31
US4866088A (en) 1989-09-12
ATE56139T1 (de) 1990-09-15
GR3000838T3 (en) 1991-11-15
EP0244315B1 (fr) 1990-09-05
FR2598081A1 (fr) 1987-11-06
DE3764700D1 (de) 1990-10-11
JPS6393712A (ja) 1988-04-25

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