[go: up one dir, main page]

ES2014042A6 - Un procedimiento para la preparacion de una composicion de 1-(2'-desoxi -2' fluor -b- d- arabinofuranosil) -5-etiluracilo. - Google Patents

Un procedimiento para la preparacion de una composicion de 1-(2'-desoxi -2' fluor -b- d- arabinofuranosil) -5-etiluracilo.

Info

Publication number
ES2014042A6
ES2014042A6 ES8802716A ES8802716A ES2014042A6 ES 2014042 A6 ES2014042 A6 ES 2014042A6 ES 8802716 A ES8802716 A ES 8802716A ES 8802716 A ES8802716 A ES 8802716A ES 2014042 A6 ES2014042 A6 ES 2014042A6
Authority
ES
Spain
Prior art keywords
composition
etiluracilo
desoxi
arabinofuranosil
fluor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8802716A
Other languages
English (en)
Inventor
Jack J Fox
Kyoichi A Watanabe
Carlos Lopez
Christian G Trepo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Memorial Sloan Kettering Cancer Center
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Memorial Sloan Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Memorial Sloan Kettering Cancer Center filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of ES2014042A6 publication Critical patent/ES2014042A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION DE 1-(2''-DESOXI-2''-FLUOR- D-ARABINOFURANOSIL)-5-ETILURACILO. COMPRENDE MEZCLAR EL INGREDIENTE ACTIVO CON UN VEHICULO FARMACEUTICAMENTE ACEPTABLE, MEDIANTE GRANULACION EN HUMEDO DE LA MEZCLA SEGUIDA O NO DE COMPRESION, COMPRESION DIRECTA DE LA MEZCLA, INCORPORACION DE LA MISMA EN CAPSULAS DE GELATINA DURA O BLANDA, DISOLUCION DE LA MEZCLA EN AGUA O SOLUCIONES ACUOSAS ESTERILES, FUSION DE UNA BASE GRASA PARA SUPOSITORIOS E INCORPORACION EN ELLA DE LA MEZCLA O INCORPORACION DEL INGREDIENTE ACTIVO EN GOMAS O PARAFINAS PARA LA OBTENCION DE UNGUENTOS Y PASTAS. LA COMPOSICION ASI OBTENIDA TIENE APLICACION EN EL TRATAMIENTO DE LAS INFECCIONES PRODUCIDAS POR EL VIRUS DE LA HEPATITIS.
ES8802716A 1987-09-03 1988-09-02 Un procedimiento para la preparacion de una composicion de 1-(2'-desoxi -2' fluor -b- d- arabinofuranosil) -5-etiluracilo. Expired - Lifetime ES2014042A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9244687A 1987-09-03 1987-09-03

Publications (1)

Publication Number Publication Date
ES2014042A6 true ES2014042A6 (es) 1990-06-16

Family

ID=22233256

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8802716A Expired - Lifetime ES2014042A6 (es) 1987-09-03 1988-09-02 Un procedimiento para la preparacion de una composicion de 1-(2'-desoxi -2' fluor -b- d- arabinofuranosil) -5-etiluracilo.

Country Status (10)

Country Link
EP (1) EP0338042B1 (es)
JP (1) JPH02500524A (es)
KR (1) KR970011386B1 (es)
AU (1) AU2487688A (es)
CA (1) CA1328865C (es)
DE (1) DE3885090T2 (es)
ES (1) ES2014042A6 (es)
IL (1) IL87646A (es)
PT (1) PT88420B (es)
WO (1) WO1989001776A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
DK1058686T3 (da) * 1998-02-25 2007-03-05 Univ Emory 2'-fluornukleosider
US20030087873A1 (en) * 2000-10-18 2003-05-08 Lieven Stuyver Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211733A (en) * 1978-12-26 1980-07-08 Chang Shih Chih Gas-liquid mixing process and apparatus
HU198393B (en) * 1984-03-06 1989-10-30 Sloan Kettering Inst Cancer Process for production of medical composition suitable for treatment of hepatitis containing as active substance derivatives of piramidin-nucleoside
US4666892A (en) * 1984-03-06 1987-05-19 Sloan-Kettering Memorial Cancer Center Method and composition for hepatitis treatment with pyrimidine nucleoside compounds

Also Published As

Publication number Publication date
KR970011386B1 (ko) 1997-07-10
CA1328865C (en) 1994-04-26
EP0338042B1 (en) 1993-10-20
EP0338042A4 (en) 1990-09-26
JPH02500524A (ja) 1990-02-22
IL87646A (en) 1994-07-31
DE3885090T2 (de) 1994-05-11
PT88420A (pt) 1989-07-31
EP0338042A1 (en) 1989-10-25
DE3885090D1 (de) 1993-11-25
AU2487688A (en) 1989-03-31
PT88420B (pt) 1993-12-31
KR890701112A (ko) 1989-12-19
WO1989001776A1 (en) 1989-03-09

Similar Documents

Publication Publication Date Title
AR240251A1 (es) Metodo para preparar una composicion para tratamiento de infecciones virales y un metodo para sintetizar 3' azido 2', 3' dideoxiuridina destinada a la preparacion de dicha composicion.
EP1852121A3 (en) Lipid analogs for treating viral infections
AU7144901A (en) Human papilloma virus treatment
FR2543550B1 (fr) Nouveaux derives de la tetrahydroxy-3', 4',5,7 flavone, leur methode de preparation et leur emploi therapeutique
DK0973735T3 (da) Polyaromatiske antivirale præparater
EE9700225A (et) Meetod diabetes mellituse raviks, kasutades KKF
EP0276279A4 (en) PREPARATION AND METHOD FOR IMMUNIZING AGAINST VIRAL AIDS AND ARC PATHOGENS.
ATE103982T1 (de) Rekombinant hergestellte blutfaktoren, verfahren zur exprimierung besagter blutfaktoren sowie in besagtem prozess verwendeter rekombinanter vaccina-virus.
ES2038650T3 (es) Procedimiento para preparar una composicion farmaceutica que comprende 3'-desoxitimidin-2'-eno-(3'-desoxi-2',3'-dideshidrotimidina) para tratar pacientes infectados con retrovirus.
UA26853C2 (uk) Спосіб одержаhhя стабільhого соматотропіhу, стабільhий соматотропіh і композиція стабільhого соматотропіhу
UA35639C2 (uk) Спосіб одержання композиції очищеного капсидного білка вірусу папіломи людини
ES542430A0 (es) Un procedimiento para la preparacion de una composicion antiacida de alginato de magnesio.
ES2014042A6 (es) Un procedimiento para la preparacion de una composicion de 1-(2'-desoxi -2' fluor -b- d- arabinofuranosil) -5-etiluracilo.
BG44379A3 (en) Method for preparing of 9- chlor- 1, 5- benzothiazepine derivatives
PT87004A (pt) Process for the preparation of compositions for the treatment of viral infections and composites 3'-azide-2',3'-didesoxy-in osine and 3'-fluoro-2',3'-didesoxyguanosine
IT8349344A0 (it) Calizzatore, nonche' metodo per lapreparazione ed utilizzazioni
IT9020020A0 (it) "n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono
ES8704962A1 (es) Un procedimiento para preparar 1b-d-ribofuranosil, 1-2-4-triazol-3-carboxamida.
BR8906377A (pt) Agente para a fixacao do penteado e para o tratamento dos cabelos
BG90414A (bg) 2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им
BR8704108A (pt) Composto de cerio,processo de preparacao de alcanolatoamida cerica,composicao e alcanolatoamina cerica
UA37251C2 (uk) Лікарський засіб для лікування або профілактики вірусної інфекції гепатиту в і спосіб лікування вірусної інфекції гепатиту в
NZ213370A (en) Method of treating viral infections of selected trees and field crops using ribavirin (1-b-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) or the 2,3,5-triacetyl or 5'-butyryl derivative thereof
BR8901200A (pt) Composicao anti-espuma solida,composicao agroquimica e processo para preparacao das mesmas
EA199900006A1 (ru) Препарат и способ для лечения застоной сердечной недостаточности

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-09-02