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ES2008151A6 - Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicas - Google Patents

Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicas

Info

Publication number
ES2008151A6
ES2008151A6 ES8702234A ES8702234A ES2008151A6 ES 2008151 A6 ES2008151 A6 ES 2008151A6 ES 8702234 A ES8702234 A ES 8702234A ES 8702234 A ES8702234 A ES 8702234A ES 2008151 A6 ES2008151 A6 ES 2008151A6
Authority
ES
Spain
Prior art keywords
peptides
diagnostic kits
protein
antimalarial vaccines
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8702234A
Other languages
English (en)
Inventor
Adriano Bernardi
Fabio Bonelli
Antonello Pessi
Antonio Silvio Verdini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eni Tecnologie SpA
Original Assignee
Eniricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche SpA filed Critical Eniricerche SpA
Publication of ES2008151A6 publication Critical patent/ES2008151A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN POLIPEPTIDO CONSTITUIDO POR UN PEPTIDO DE SINTESIS QUE REPITE LA REGION 1 DE P. FALCIPARUM Y POR UN NUMERO VARIABLE DE UNIDADES DEL TETRAPEPTIDO REPETITIVAS DE LA PROTEINA CS DE P. FALCIPARUM VINCULADAS ENTRE SI MEDIANTE ENLACE AMIDICO ENTRE LA PROLINA TERMINAL DE LA REGION 1 Y LA ASPARAGINA INICIAL DEL PRIMER TETRAPEPTIDO, CONSISTENTE EN UN PROCESO DE SINTESIS EN FASE SOLIDA QUE COMPRENDE UNA SERIE DE CONDENSACIONES SUCESIVAS DE DIVERSOS AMINOACIDOS A UN SOPORTE SOLIDO INSOLUBLE MEDIANTE RESPECTIVAS REACCIONES DE ESTERIFICACION Y ACILACION, EL DESBLOQUEO DEL POLIPEPTIDO ASI OBTENIDO DEL SOPORTE SOLIDO INSOLUBLE MEDIANTE HIDROLISIS ACIDA, Y SU RECUPERACION Y PURIFICACION MEDIANTE CROMATOGRAFIA. DICHO POLIPEPTIDO ES UTIL PARA LA OBTENCION DE VACUNAS CONTRA LA MALARIA Y PARA LA DETECCION DE ENFERMEDADES PALUDICAS.
ES8702234A 1986-07-16 1987-07-14 Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicas Expired ES2008151A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21144/86A IT1196501B (it) 1986-07-16 1986-07-16 Polipeptide utile per la preparazione di vaccini per la malaria e di kits diagnostici per la determinazione di affezioni malariche

Publications (1)

Publication Number Publication Date
ES2008151A6 true ES2008151A6 (es) 1989-07-16

Family

ID=11177390

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8702234A Expired ES2008151A6 (es) 1986-07-16 1987-07-14 Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicas

Country Status (13)

Country Link
AT (1) ATA179087A (es)
BE (1) BE1000729A4 (es)
CH (1) CH673461A5 (es)
DE (1) DE3723583A1 (es)
ES (1) ES2008151A6 (es)
FR (1) FR2601590B1 (es)
GB (1) GB2193215B (es)
GR (1) GR871021B (es)
IT (1) IT1196501B (es)
NL (1) NL8701686A (es)
OA (1) OA08626A (es)
SE (1) SE468393B (es)
ZA (1) ZA874778B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2006700A1 (en) * 1989-01-17 1990-07-17 Antonello Pessi Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines
CA2031468A1 (en) * 1989-12-08 1991-06-09 Mitchell S. Gross Malaria vaccine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707357A (en) * 1984-06-26 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
PT82282B (pt) * 1985-03-28 1988-02-17 Univ New York Processo de preparacao de um conjugado de proteina de suporte-antigeno imunogenico para uso como vacina contra malaria
IT1187710B (it) * 1985-07-25 1987-12-23 Eniricerche Spa Composizione peptidica utile per la preparazione di vaccini per la malaria e di kit diagnostici per la determinazione di affezioni malariche

Also Published As

Publication number Publication date
GB8715737D0 (en) 1987-08-12
IT8621144A0 (it) 1986-07-16
ATA179087A (de) 1996-07-15
BE1000729A4 (fr) 1989-03-21
FR2601590B1 (fr) 1990-05-18
SE468393B (sv) 1993-01-11
DE3723583C2 (es) 1991-06-13
FR2601590A1 (fr) 1988-01-22
ZA874778B (en) 1988-01-13
SE8702698D0 (sv) 1987-06-30
DE3723583A1 (de) 1988-01-28
CH673461A5 (es) 1990-03-15
NL8701686A (nl) 1988-02-16
SE8702698L (sv) 1988-01-17
GR871021B (en) 1987-11-13
GB2193215B (en) 1990-03-07
IT1196501B (it) 1988-11-16
GB2193215A (en) 1988-02-03
OA08626A (en) 1988-11-30

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