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ES2003315T3 - Aparato y procedimiento para oxigenar una formulacion portadora de oxigeno disuelto en estado liquido. - Google Patents

Aparato y procedimiento para oxigenar una formulacion portadora de oxigeno disuelto en estado liquido.

Info

Publication number
ES2003315T3
ES2003315T3 ES198787308354T ES87308354T ES2003315T3 ES 2003315 T3 ES2003315 T3 ES 2003315T3 ES 198787308354 T ES198787308354 T ES 198787308354T ES 87308354 T ES87308354 T ES 87308354T ES 2003315 T3 ES2003315 T3 ES 2003315T3
Authority
ES
Spain
Prior art keywords
door
sack
gas
tank
way valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787308354T
Other languages
English (en)
Other versions
ES2003315A4 (es
Inventor
Charles Michael Heldebrant
Kim Christensen Crowe
George Raymond Groveman
Charles Harry Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Therapeutic Corp
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Publication of ES2003315A4 publication Critical patent/ES2003315A4/es
Application granted granted Critical
Publication of ES2003315T3 publication Critical patent/ES2003315T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/32—Oxygenators without membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/03—Heart-lung
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00—Gas and liquid contact apparatus
    • Y10S261/28—Blood oxygenators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/102499—Blood gas standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

FORMULACIONES DE EMULSION DE PERFLUOROCARBONOS SE OXIGENAN ANTES DE SU USO POR MEDIO DE UN SISTEMA DE OXIGENACION (10). EL SUSTITUTIVO DEL SANGRADO ESTA EN UN RECIPIENTE CERRADO O SACO (12). EL GAS QUE CONTIENE OXIGENO SE INTRODUCE EN EL SACO (12) DESDE UN RECIPIENTE CERRADO (18). EL SACO (12) SE AGITA CONTINUAMENTE DURANTE UN TIEMPO SUFICIENTE PARA AUMENTAR EL PO2 DE LAS FORMULACIONES DE EMULSION DE PERFLUOROCARBONOS HASTA LA PRESION DESEADA, POR EJEMPLO HASTA 600 MM HG POR LO MENOS. EN UNA INCORPORACION, EL SISTEMA (10) UTILIZADO PARA LA OXIGENACION DE LAS FORMULACIONES DE EMULSION DE PERFLUOROCARBONOS COMPRENDE UN PEQUEÑO DEPOSITO (50) PARA GAS, QUE TIENE UNA PUERTA DE ENTRADA (52) Y UNA PUERTA DE SALIDA (56) AJUSTADA CON VALVULAS DE CIERRE (54, 62). LA PUERTA DE SALIDA (56) SE ADAPTA PARA SER CONECTADA A UN FILTRO (16), QUE A SU VEZ SE ADAPTA PARA SER CONECTADO A LA PUERTA DE ENTRADA (34) CON UNA VALVULA DE TRES VIAS (14). LA SALIDA PRIMARIA (38) DE LA VALVULA DE TRES VIAS (14) SEADAPTA PARA MONTAR UNA AGUJA HIPODERMICA QUE SE ADAPTA PARA SER EMPUJADA A TRAVES DE UN SEPTO DE GOMA EN UNA PUERTA (30) DEL SACO (12) PARA COMUNICAR CON SU INTERIOR. EL DEPOSITO (50) SE ADAPTA PARA LLENARLO CON GAS QUE CONTIENE OXIGENO, TAL COMO CARBOGENO, PROCEDENTE DE UNA FUENTE DE GAS PRINCIPAL (20) BAJO PRESION. EL DEPOSITO (50), EL FILTRO (16), LA VALVULA DE TRES VIAS (14) Y LA AGUJA SE CONECTAN EN SERIE,, Y SE PERMITE QUE EL GAS QUE CONTIENE OXIGENO FLUYA DEL DEPOSITO (50) AL SACO (12) QUE CONTIENE LA FORMULACION DE EMULSION. DESPUES QUE SE INTRODUCE EL GAS EN EL SACO (12), LA VALVULA DE TRES VIAS (14) SE CIERRA PARA IMPEDIR LA SALIDA DEL GAS DESDE EL RECIPIENTE (12). LUEGO SE AGITA EL RECIPIENTE (12) PARA OXIGENAR LA FORMULACION DE EMULSION.
ES198787308354T 1986-09-23 1987-09-21 Aparato y procedimiento para oxigenar una formulacion portadora de oxigeno disuelto en estado liquido. Expired - Lifetime ES2003315T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/910,521 US4769241A (en) 1986-09-23 1986-09-23 Apparatus and process for oxygenation of liquid state dissolved oxygen-carrying formulation

Publications (2)

Publication Number Publication Date
ES2003315A4 ES2003315A4 (es) 1988-11-01
ES2003315T3 true ES2003315T3 (es) 1992-04-16

Family

ID=25428925

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787308354T Expired - Lifetime ES2003315T3 (es) 1986-09-23 1987-09-21 Aparato y procedimiento para oxigenar una formulacion portadora de oxigeno disuelto en estado liquido.

Country Status (8)

Country Link
US (2) US4769241A (es)
EP (1) EP0265082B1 (es)
JP (1) JPS63132827A (es)
AT (1) ATE67680T1 (es)
CA (1) CA1288045C (es)
DE (2) DE265082T1 (es)
ES (1) ES2003315T3 (es)
GR (1) GR3003171T3 (es)

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Also Published As

Publication number Publication date
US4919895A (en) 1990-04-24
DE265082T1 (de) 1988-11-24
US4769241A (en) 1988-09-06
GR3003171T3 (en) 1993-02-17
EP0265082A1 (en) 1988-04-27
DE3773324D1 (de) 1991-10-31
ES2003315A4 (es) 1988-11-01
ATE67680T1 (de) 1991-10-15
EP0265082B1 (en) 1991-09-25
JPS63132827A (ja) 1988-06-04
CA1288045C (en) 1991-08-27

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