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ES2000178A6 - Procedimiento para producir una secuencia de polipeptidos y metodo para purificar una sustancia. - Google Patents

Procedimiento para producir una secuencia de polipeptidos y metodo para purificar una sustancia.

Info

Publication number
ES2000178A6
ES2000178A6 ES8600023A ES8600023A ES2000178A6 ES 2000178 A6 ES2000178 A6 ES 2000178A6 ES 8600023 A ES8600023 A ES 8600023A ES 8600023 A ES8600023 A ES 8600023A ES 2000178 A6 ES2000178 A6 ES 2000178A6
Authority
ES
Spain
Prior art keywords
binding
fibrin
collagen
useful
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600023A
Other languages
English (en)
Inventor
Francisco E Baralle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albumedix Ltd
Original Assignee
Delta Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delta Biotechnology Ltd filed Critical Delta Biotechnology Ltd
Publication of ES2000178A6 publication Critical patent/ES2000178A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Inorganic Fibers (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Materials For Medical Uses (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE HA DETERMINADO LA SECUENCIA DE POLIPEPTIDOS DE LAS PARTES DE FIJACION AL COLAGENO Y DE FIJACION A LA FIBRINA DE FIBRONECTINA Y LAS CORRESPONDIENTES SECUENCIAS DE ADNC. EL POLIPEPTIDO DE FIJACION AL COLAGENO ES UTIL EN METODOS DE PURIFICACION, Y EL POLIPEPTIDO DE FIJACION A LA FIBRINA ES UTIL PARA DIRIGIR SUSTANCIAS TERAPEUTICAS SOBRE FIBRINA NATURAL.
ES8600023A 1985-06-28 1986-06-27 Procedimiento para producir una secuencia de polipeptidos y metodo para purificar una sustancia. Expired ES2000178A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858516421A GB8516421D0 (en) 1985-06-28 1985-06-28 Fibronectins

Publications (1)

Publication Number Publication Date
ES2000178A6 true ES2000178A6 (es) 1988-01-01

Family

ID=10581489

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600023A Expired ES2000178A6 (es) 1985-06-28 1986-06-27 Procedimiento para producir una secuencia de polipeptidos y metodo para purificar una sustancia.

Country Status (10)

Country Link
EP (1) EP0207751B1 (es)
JP (1) JPS6289699A (es)
AT (1) ATE58381T1 (es)
AU (1) AU603059B2 (es)
DE (1) DE3675591D1 (es)
DK (1) DK306386A (es)
ES (1) ES2000178A6 (es)
FI (1) FI862756L (es)
GB (1) GB8516421D0 (es)
ZA (1) ZA864791B (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3716513A1 (de) * 1987-05-16 1988-11-24 Basf Ag Proteine mit tnf-wirkung
US5019646A (en) * 1987-08-25 1991-05-28 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
JPH0829098B2 (ja) * 1988-01-05 1996-03-27 寳酒造株式会社 細胞接着活性ポリペプチド
JP2561113B2 (ja) * 1988-02-16 1996-12-04 寳酒造株式会社 細胞接着活性ポリペプチド
JP2561122B2 (ja) * 1988-04-13 1996-12-04 寳酒造株式会社 機能性ポリペプチド
DE68923613T2 (de) * 1988-06-14 1996-01-04 Chiron Corp Superoxid-dismutaseanaloge mit neuen bindeeigenschaften.
JP2561131B2 (ja) * 1988-06-30 1996-12-04 寳酒造株式会社 細胞接着活性ポリペプチド
JP2561526B2 (ja) * 1988-12-02 1996-12-11 寳酒造株式会社 細胞接着活性ポリペプチド
US7087722B1 (en) * 1988-12-29 2006-08-08 Savient Pharmaceuticals, Inc. Fibrin binding domain polypeptides and uses and methods of producing same
US5679320A (en) * 1988-12-29 1997-10-21 Bio-Technology General Corp. Fibrin binding domain polypeptides and uses and methods of producing same
JP3095771B2 (ja) * 1988-12-29 2000-10-10 バイオ―テクノロジー・ジエネラル・コーポレイシヨン ヒトフィブロネクチンポリペプチド類似体のクローニング及び製造並びにこのようなポリペプチド類似体の使用法
US5270030A (en) * 1988-12-29 1993-12-14 Bio-Technology General Corp. Fibrin binding domain polypeptide and method of producing
WO1990008833A1 (en) * 1989-02-02 1990-08-09 Massachusetts Institute Of Technology Expression of recombinant fibronectin in genetically engineered cells
JP2878341B2 (ja) * 1989-03-03 1999-04-05 学校法人藤田学園 人工機能性ポリペプチド
ATE92107T1 (de) * 1989-04-29 1993-08-15 Delta Biotechnology Ltd N-terminale fragmente von menschliches serumalbumin enthaltenden fusionsproteinen.
JP2561149B2 (ja) * 1989-05-26 1996-12-04 寳酒造株式会社 機能性ポリペプチド
US5198423A (en) * 1989-05-26 1993-03-30 Takara Shuzo Co., Ltd. Functional polypeptide containing a cell binding domain and a heparin binding domain of fibronectin
EP0428266B1 (en) * 1989-10-13 1994-09-28 Takara Shuzo Co. Ltd. Anticancer agent
GB9023149D0 (en) * 1990-10-24 1990-12-05 British Bio Technology Proteins and nucleic acids
WO1993020228A1 (en) * 1992-03-31 1993-10-14 Toray Industries, Inc. Novel, physiologically active protein and hemopoietic stem cell growth promoter
WO1994016085A2 (en) * 1992-12-30 1994-07-21 Zymogenetics, Inc. Hybrid proteins having cross-linking and tissue-binding activities
JP3192067B2 (ja) * 1995-10-09 2001-07-23 科学技術振興事業団 ペプチドとコラーゲン収縮阻害剤
CA2235629A1 (en) 1995-11-13 1997-05-22 Takara Shuzo Co., Ltd. Method for gene transfer into target cells with retrovirus
JP2780160B2 (ja) * 1996-04-22 1998-07-30 寳酒造株式会社 機能性ポリペプチド
JP2780159B2 (ja) * 1996-04-22 1998-07-30 寳酒造株式会社 機能性ポリペプチド遺伝子
JP2777986B2 (ja) * 1996-04-22 1998-07-23 寳酒造株式会社 機能性ポリペプチド
DE69734601T2 (de) 1996-05-16 2006-08-03 The Texas A & M University System, College Station Zusammensetzung von kollagenbindungsprotein und verfahren zu deren verwendungen
US5922676A (en) * 1996-09-20 1999-07-13 The Burnham Institute Methods of inhibiting cancer by using superfibronectin
GB9726539D0 (en) * 1997-12-16 1998-02-11 Univ Dundee Polypeptides, polynucleotides and uses thereof
AU2001278737A1 (en) * 2000-08-15 2002-02-25 Terumo Kabushiki Kaisha Collagen-binding hybrid polypeptide
WO2003016511A1 (fr) 2001-08-15 2003-02-27 Takara Bio Inc. Procede permettant une culture etendue de lymphocytes t cytotoxiques specifiques d'un antigene
US7094549B2 (en) * 2001-11-23 2006-08-22 Syn X Pharma, Inc. Fibronectin biopolymer marker indicative of insulin resistance
GB0201273D0 (en) * 2002-01-21 2002-03-06 Isis Innovation Fibronectin variants and screening methods
DE60335253D1 (de) 2002-03-25 2011-01-20 Takara Bio Inc Verfahren zur produktion eines zytotoxischen lymphozyten
KR20060039940A (ko) * 2003-08-22 2006-05-09 다카라 바이오 가부시키가이샤 세포 상해성 림프구의 제조 방법
CN101243187B (zh) 2005-08-17 2012-07-11 宝生物工程株式会社 淋巴细胞的制备方法
EP2155874B1 (en) 2007-04-09 2016-05-11 The Board Of Trustees Of The University Of Arkansas Fusion proteins of collagen-binding domain and parathyroid hormone
JP6366507B2 (ja) 2011-12-14 2018-08-01 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー コラーゲン結合タンパク質による治療剤の送達
US9526765B2 (en) 2012-02-09 2016-12-27 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
US11624060B2 (en) 2017-02-10 2023-04-11 The Board Of Trustees Of The University Of Arkansas Collagen-binding agent compositions and methods of using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH472219A (de) * 1963-06-15 1969-05-15 Spofa Vereinigte Pharma Werke Hochporöse Kollagen-Gewebe-Blutgefässprothese und Verfahren zur Herstellung derselben
US3272204A (en) * 1965-09-22 1966-09-13 Ethicon Inc Absorbable collagen prosthetic implant with non-absorbable reinforcing strands
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
WO1984000540A1 (en) * 1982-08-04 1984-02-16 Jolla Cancer Res Found Polypeptide
JPS59134732A (ja) * 1983-01-21 1984-08-02 Green Cross Corp:The フイブロネクチン・生理活性物質複合体の製造法

Also Published As

Publication number Publication date
AU5931586A (en) 1987-01-08
EP0207751A1 (en) 1987-01-07
DE3675591D1 (en) 1990-12-20
EP0207751B1 (en) 1990-11-14
ATE58381T1 (de) 1990-11-15
ZA864791B (en) 1987-02-25
DK306386D0 (da) 1986-06-27
JPS6289699A (ja) 1987-04-24
FI862756A7 (fi) 1986-12-29
DK306386A (da) 1986-12-29
FI862756A0 (fi) 1986-06-27
GB8516421D0 (en) 1985-07-31
AU603059B2 (en) 1990-11-08
FI862756L (fi) 1986-12-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980504