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ES2000058A6 - Un procedimiento para preparar deircados de ester de fosfato - Google Patents

Un procedimiento para preparar deircados de ester de fosfato

Info

Publication number
ES2000058A6
ES2000058A6 ES8600448A ES8600448A ES2000058A6 ES 2000058 A6 ES2000058 A6 ES 2000058A6 ES 8600448 A ES8600448 A ES 8600448A ES 8600448 A ES8600448 A ES 8600448A ES 2000058 A6 ES2000058 A6 ES 2000058A6
Authority
ES
Spain
Prior art keywords
phosphate ester
preparation
therapeutic use
ester derivatives
ester group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600448A
Other languages
English (en)
Inventor
Norio Nakamura
Nobuyuki Ookawa
Hiroyuki Koike
Toshio Sada
Takeshi Oshima
Yoshio Iizuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES2000058A6 publication Critical patent/ES2000058A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ESTER DE FOSFATO DE FORMULA (I): (DONDE M ES 2-4, A Y B SON OXIGENO O AZUFRE Y UNO DE R1 Y R2 REPRESENTA UN GRUPO ALQUILCARBOMOILO DE CADENALARGA Y EL OTRO REPRESENTA UN GRUPO ESTER FOSFATO DE AMONIOALQUILO) SON ANTAGONISTAS DE FAP QUE SE UTILIZAN PARA TRATAR ASMA, HIPOTENSION, INFLAMACION Y CHOQUE. SE PUEDEN PREPARAR PORREACCION DEL COMPUESTO CORRESPONDIENTE QUE TIENE UN GRUPO ESTER FOSFATO DE HALOALQUILO O UN GRUPO ESTER FOSFATO DE ALQUILENO EN LUGAR DEL GRUPO ESTER FOSFATO DE AMONIOALQUILO CON UNA AMINA APROPIADA.
ES8600448A 1985-07-26 1986-07-21 Un procedimiento para preparar deircados de ester de fosfato Expired ES2000058A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16396585 1985-07-26

Publications (1)

Publication Number Publication Date
ES2000058A6 true ES2000058A6 (es) 1987-11-16

Family

ID=15784180

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600448A Expired ES2000058A6 (es) 1985-07-26 1986-07-21 Un procedimiento para preparar deircados de ester de fosfato

Country Status (7)

Country Link
EP (1) EP0210804B1 (es)
JP (1) JPH0649713B2 (es)
KR (1) KR940005337B1 (es)
AT (1) ATE42955T1 (es)
CA (1) CA1322370C (es)
DE (1) DE3663255D1 (es)
ES (1) ES2000058A6 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950002551B1 (en) * 1986-07-04 1995-03-21 Sankyo Co Cyclic ether derivatives, their preparation and use
FR2631327B1 (fr) * 1988-05-11 1990-09-07 Inst Francais Du Petrole Synthese de nouveaux gallosilicates de structure mfi
ES2013834A6 (es) * 1989-01-30 1990-06-01 Uriach & Cia Sa J Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano.
ES2010145A6 (es) * 1989-03-02 1989-10-16 Uriach & Cia Sa J Procedimiento para la obtencion de derivados de la 2-picolilamina.
ES2062943B1 (es) * 1993-03-23 1995-11-16 Uriach & Cia Sa J Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437832C2 (de) * 1974-08-06 1986-04-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Phospholipide, Verfahren zu ihrer Herstellung sowie ihre Verwendung
US4408052A (en) * 1980-02-27 1983-10-04 Takeda Chemical Industries, Ltd. Phospholipid carbamates

Also Published As

Publication number Publication date
ATE42955T1 (de) 1989-05-15
KR940005337B1 (ko) 1994-06-17
EP0210804A1 (en) 1987-02-04
CA1322370C (en) 1993-09-21
EP0210804B1 (en) 1989-05-10
DE3663255D1 (en) 1989-06-15
JPH0649713B2 (ja) 1994-06-29
JPS62103097A (ja) 1987-05-13
KR870001223A (ko) 1987-03-12

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