[go: up one dir, main page]

ES174955A1 - A PROCEDURE OF PRODUCING A HORMON DERIVATIVE THAT DECREASES BLOOD SUGAR AS WELL AS THE INSULIN DERIVATIVE - Google Patents

A PROCEDURE OF PRODUCING A HORMON DERIVATIVE THAT DECREASES BLOOD SUGAR AS WELL AS THE INSULIN DERIVATIVE

Info

Publication number
ES174955A1
ES174955A1 ES0174955A ES174955A ES174955A1 ES 174955 A1 ES174955 A1 ES 174955A1 ES 0174955 A ES0174955 A ES 0174955A ES 174955 A ES174955 A ES 174955A ES 174955 A1 ES174955 A1 ES 174955A1
Authority
ES
Spain
Prior art keywords
derivative
blood sugar
procedure
producing
hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0174955A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Terapeutisk Laboratorium AS
Original Assignee
Novo Terapeutisk Laboratorium AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Terapeutisk Laboratorium AS filed Critical Novo Terapeutisk Laboratorium AS
Publication of ES174955A1 publication Critical patent/ES174955A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procedimiento de producir und erivado del hormón que disminuye el azúcar de la sangre en el cual este hormón se hace reaccionar por medio de reactivos que similarmente a los isocianatos ataquen los amino grupos de tal manera que un átomo o átomos de hidrógeno de dichos grupos sean sustituidos cuidándose en la elección de las condiciones de reacción habituales tales como tiempo temperatura y concentración de los componentes empleados en la reacción de que la reacción solo procede hasta un punto a que el hormón mantiene todo su efecto disminuidor del azúcar de la sangra o una parte esencial del mismo pero de carácter alterado en forma que al efecto sobre el organismo del diabético se extiende en un periodo de tiempo más largo.Procedure of producing a derivative of the hormone that lowers blood sugar in which this hormone is reacted by means of reagents that, similarly to isocyanates, attack amino groups in such a way that a hydrogen atom or atoms of said groups are substituted taking care in the choice of the usual reaction conditions such as time, temperature and concentration of the components used in the reaction that the reaction only proceeds to a point where the hormone maintains all its blood sugar lowering effect or an essential part of the same but of altered character in a way that the effect on the diabetic's organism extends over a longer period of time.

ES0174955A 1943-12-13 1946-09-13 A PROCEDURE OF PRODUCING A HORMON DERIVATIVE THAT DECREASES BLOOD SUGAR AS WELL AS THE INSULIN DERIVATIVE Expired ES174955A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK321643 1943-12-13

Publications (1)

Publication Number Publication Date
ES174955A1 true ES174955A1 (en) 1946-11-01

Family

ID=38662821

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0174955A Expired ES174955A1 (en) 1943-12-13 1946-09-13 A PROCEDURE OF PRODUCING A HORMON DERIVATIVE THAT DECREASES BLOOD SUGAR AS WELL AS THE INSULIN DERIVATIVE

Country Status (3)

Country Link
ES (1) ES174955A1 (en)
FR (1) FR933190A (en)
GB (1) GB614990A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3509120A (en) * 1966-12-28 1970-04-28 Squibb & Sons Inc N-terminal mono- and diaminoacyl-insulin
US3481917A (en) * 1967-03-06 1969-12-02 American Home Prod N - mercaptosuccinoylinsulin and n - (lower)alkanoylmercaptosuccinoylinsulin
US3528960A (en) * 1968-10-07 1970-09-15 Lilly Co Eli N-carboxyaroyl insulins

Also Published As

Publication number Publication date
GB614990A (en) 1948-12-30
FR933190A (en) 1948-04-13

Similar Documents

Publication Publication Date Title
ES174955A1 (en) A PROCEDURE OF PRODUCING A HORMON DERIVATIVE THAT DECREASES BLOOD SUGAR AS WELL AS THE INSULIN DERIVATIVE
JPS5235987A (en) Semiconductor integrated circuit
ES8607304A1 (en) Imidazolidinedione derivatives.
ES459214A1 (en) Supersaturated isosorbide dinitrate solution, process for its production and its use
GB713652A (en) Improvements in or relating to heterocyclic compounds and their manufacture
GB958866A (en) Production of ethylene sulphide
GB560859A (en) Improvements in insulin preparations
ES2072910T3 (en) USE OF A COMPOUND CONTAINING ORGANIC GERMANIUM FOR THE MANUFACTURE OF A MEDICINAL PRODUCT FOR THE TREATMENT OF AIDS.
GB818614A (en) Indicating instruments
GB571078A (en) Improvements in or relating to colour photography
ES335892A1 (en) Improvements relating to nitro acridone dyestuffs and their use
Oishi A Case of Hypernephroma with Metastasis to the Fracture Site of the Femur
GB1094810A (en) Unsaturated 4,5-seco-steroid compounds, and processes for their preparation
ES345580A1 (en) Method for preparing methylene bis (thiocyanate)
JPS5289095A (en) Display panel
GB604327A (en) Method for the production of derivatives of the blood-sugar-lowering hormone, and preparation produced by the said method
Sameshima One Case of Patellar Tuberculosis
JPS51130193A (en) Liquid crystal display equipment
ES158579A2 (en) IMPROVEMENTS MADE WITH THE PURPOSE OF THE PATENT
GB917624A (en) 2-sec.-butoxyphenyl n-methyl-carbamate
Murakawa Autoradiographic Studies of Phosphor Metabolism in the Experimetal Bone Graft Part 1 Cortical Bone Graft
ES168330A2 (en) IMPROVEMENTS MADE WITH THE PURPOSE OF THE PATENT
KASIYAMA Sasceptibility to wind damade of forests on the redion having been scarcely visited by strong winds
GR26048B (en) METHOD FOR THE PREPARATION OF 17 - CYCLOPENTYL - PROPIONIC 4 - HYDROXY - 19 - NORESTESTOSTERONE.
ES164204A2 (en)