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EP4673560A1 - Spezifische bindungselemente mit doppelindexierung zur gewinnung von verknüpften zytometrischen einzelzellen- und sequenzdaten - Google Patents

Spezifische bindungselemente mit doppelindexierung zur gewinnung von verknüpften zytometrischen einzelzellen- und sequenzdaten

Info

Publication number
EP4673560A1
EP4673560A1 EP24764411.5A EP24764411A EP4673560A1 EP 4673560 A1 EP4673560 A1 EP 4673560A1 EP 24764411 A EP24764411 A EP 24764411A EP 4673560 A1 EP4673560 A1 EP 4673560A1
Authority
EP
European Patent Office
Prior art keywords
cells
indexed
specific binding
dual
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24764411.5A
Other languages
English (en)
French (fr)
Inventor
Adam Wright
Geoffrey Osborne
Hye Won Song
Cynthia SAKOFSKY
Jody MARTIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of EP4673560A1 publication Critical patent/EP4673560A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP24764411.5A 2023-02-28 2024-02-26 Spezifische bindungselemente mit doppelindexierung zur gewinnung von verknüpften zytometrischen einzelzellen- und sequenzdaten Pending EP4673560A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363448935P 2023-02-28 2023-02-28
PCT/US2024/017296 WO2024182293A1 (en) 2023-02-28 2024-02-26 Dual indexing specific binding members for obtaining linked single cell cytometric and sequence data

Publications (1)

Publication Number Publication Date
EP4673560A1 true EP4673560A1 (de) 2026-01-07

Family

ID=92590904

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24764411.5A Pending EP4673560A1 (de) 2023-02-28 2024-02-26 Spezifische bindungselemente mit doppelindexierung zur gewinnung von verknüpften zytometrischen einzelzellen- und sequenzdaten

Country Status (3)

Country Link
EP (1) EP4673560A1 (de)
CN (1) CN120858182A (de)
WO (1) WO2024182293A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160266094A1 (en) * 2015-03-13 2016-09-15 University Of Iowa Research Foundation Cellular barcode
EP3516400B1 (de) * 2016-09-26 2023-08-16 Becton, Dickinson and Company Messung der proteinexpression mit reagenzien mit strichcodierten oligonukleotidsequenzen
CA3059559A1 (en) * 2017-06-05 2018-12-13 Becton, Dickinson And Company Sample indexing for single cells
EP3837380A4 (de) * 2018-08-17 2022-05-11 Cellecta, Inc. Multiplex-präparation von barcodierten genspezifischen dns-fragmenten
CN115298322A (zh) * 2020-01-17 2022-11-04 贝克顿迪金森公司 用于单细胞分泌组学的方法和组合物
EP4111168A1 (de) * 2020-02-25 2023-01-04 Becton Dickinson and Company Bispezifische sonden zur ermöglichung der verwendung von einzelzellenproben als einzelfarbkompensationssteuerung

Also Published As

Publication number Publication date
WO2024182293A1 (en) 2024-09-06
CN120858182A (zh) 2025-10-28

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