EP4337788C0 - SPATIAL ANALYSIS OF A PLANAR BIOLOGICAL SAMPLE - Google Patents
SPATIAL ANALYSIS OF A PLANAR BIOLOGICAL SAMPLEInfo
- Publication number
- EP4337788C0 EP4337788C0 EP22738016.9A EP22738016A EP4337788C0 EP 4337788 C0 EP4337788 C0 EP 4337788C0 EP 22738016 A EP22738016 A EP 22738016A EP 4337788 C0 EP4337788 C0 EP 4337788C0
- Authority
- EP
- European Patent Office
- Prior art keywords
- biological sample
- spatial analysis
- planar biological
- planar
- spatial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012472 biological sample Substances 0.000 title 1
- 238000012732 spatial analysis Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP24208453.1A EP4502179A2 (en) | 2021-06-24 | 2022-06-23 | Spatial analysis of a planar biological sample |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163214701P | 2021-06-24 | 2021-06-24 | |
| US202163257456P | 2021-10-19 | 2021-10-19 | |
| PCT/IB2022/055849 WO2022269543A2 (en) | 2021-06-24 | 2022-06-23 | Spatial analysis of a planar biological sample |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24208453.1A Division EP4502179A2 (en) | 2021-06-24 | 2022-06-23 | Spatial analysis of a planar biological sample |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP4337788A2 EP4337788A2 (en) | 2024-03-20 |
| EP4337788B1 EP4337788B1 (en) | 2024-10-30 |
| EP4337788C0 true EP4337788C0 (en) | 2024-10-30 |
Family
ID=82403540
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24208453.1A Pending EP4502179A2 (en) | 2021-06-24 | 2022-06-23 | Spatial analysis of a planar biological sample |
| EP22738016.9A Active EP4337788B1 (en) | 2021-06-24 | 2022-06-23 | Spatial analysis of a planar biological sample |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24208453.1A Pending EP4502179A2 (en) | 2021-06-24 | 2022-06-23 | Spatial analysis of a planar biological sample |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12227797B2 (en) |
| EP (2) | EP4502179A2 (en) |
| JP (1) | JP2024527509A (en) |
| AU (1) | AU2022296056A1 (en) |
| CA (1) | CA3223257A1 (en) |
| WO (1) | WO2022269543A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111801350A (en) * | 2018-01-30 | 2020-10-20 | 拉什大学医学中心 | Sequential staining for multiplex analysis of tissues and cells |
| WO2023144685A1 (en) | 2022-01-26 | 2023-08-03 | Moleculent Ab | Detection of proximity assay products in situ |
| WO2024141901A1 (en) * | 2022-12-28 | 2024-07-04 | Moleculent Ab | Heat-based transfer of reaction products made in situ to a planar support |
| WO2024154075A1 (en) * | 2023-01-18 | 2024-07-25 | Pixelgen Technologies Ab | Gap-fill ligation and primer extension reactions employing exonuclease-resistant or capture moiety means |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5264722A (en) | 1992-06-12 | 1993-11-23 | The United States Of America As Represented By The Secretary Of The Navy | Nanochannel glass matrix used in making mesoscopic structures |
| US5332681A (en) | 1992-06-12 | 1994-07-26 | The United States Of America As Represented By The Secretary Of The Navy | Method of making a semiconductor device by forming a nanochannel mask |
| US6027890A (en) | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
| US5855716A (en) | 1996-09-24 | 1999-01-05 | The United States Of America As Represented By The Secretary Of The Navy | Parallel contact patterning using nanochannel glass |
| US5976444A (en) | 1996-09-24 | 1999-11-02 | The United States Of America As Represented By The Secretary Of The Navy | Nanochannel glass replica membranes |
| US6483640B1 (en) | 1997-04-08 | 2002-11-19 | The United States Of America As Represented By The Secretary Of The Navy | Optical notch filters based on two-dimensional photonic band-gap materials |
| WO1999011813A2 (en) | 1997-09-04 | 1999-03-11 | Bayer Corporation | Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof |
| US5948902A (en) | 1997-11-20 | 1999-09-07 | South Alabama Medical Science Foundation | Antisense oligonucleotides to human serine/threonine protein phosphatase genes |
| US6087274A (en) | 1998-03-03 | 2000-07-11 | The United States Of America As Represented By The Secretary Of The Navy | Nanoscale X-Y-Z translation of nanochannel glass replica-based masks for making complex structures during patterning |
| US6969615B2 (en) * | 1999-07-26 | 2005-11-29 | 20/20 Genesystems, Inc. | Methods, devices, arrays and kits for detecting and analyzing biomolecules |
| US20050233340A1 (en) | 2004-04-20 | 2005-10-20 | Barrett Michael T | Methods and compositions for assessing CpG methylation |
| US20110275077A1 (en) | 2009-01-12 | 2011-11-10 | William James | Oligonucleotide-Coated Affinity Membranes and Uses Thereof |
| WO2011150316A1 (en) | 2010-05-28 | 2011-12-01 | Sridharan Rajagopalan | Obtaining analytes from a tissue specimen |
| WO2012057689A1 (en) | 2010-10-29 | 2012-05-03 | Ge Healthcare Bio-Sciences Ab | Proximity ligation technology for western blot applications |
| GB201106254D0 (en) * | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| US20180057873A1 (en) * | 2015-04-17 | 2018-03-01 | Centrillion Technology Holdings Corporation | Methods for performing spatial profiling of biological materials |
| EP3957747A1 (en) * | 2015-07-27 | 2022-02-23 | Illumina, Inc. | Spatial mapping of nucleic acid sequence information |
| US11530438B2 (en) | 2017-03-01 | 2022-12-20 | The Board Of Trustees Of The Leland Stanford Junior University | Highly specific circular proximity ligation assay |
| US20220025447A1 (en) | 2018-12-10 | 2022-01-27 | 10X Genomics, Inc. | Generating spatial arrays with gradients |
| WO2020160044A1 (en) | 2019-01-28 | 2020-08-06 | The Broad Institute, Inc. | In-situ spatial transcriptomics |
| WO2020180645A1 (en) * | 2019-03-01 | 2020-09-10 | Meso Scale Technologies, Llc. | Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same |
| EP3887542A1 (en) * | 2019-03-22 | 2021-10-06 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| EP4025711A2 (en) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| JP2023514749A (en) * | 2020-02-21 | 2023-04-07 | １０エックス ジェノミクス インコーポレイテッド | Methods and compositions for integrated in situ spatial assays |
| AU2021366701A1 (en) | 2020-10-22 | 2023-05-04 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification |
-
2022
- 2022-06-23 EP EP24208453.1A patent/EP4502179A2/en active Pending
- 2022-06-23 EP EP22738016.9A patent/EP4337788B1/en active Active
- 2022-06-23 CA CA3223257A patent/CA3223257A1/en active Pending
- 2022-06-23 JP JP2023578165A patent/JP2024527509A/en active Pending
- 2022-06-23 US US18/569,594 patent/US12227797B2/en active Active
- 2022-06-23 WO PCT/IB2022/055849 patent/WO2022269543A2/en active Application Filing
- 2022-06-23 AU AU2022296056A patent/AU2022296056A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2022296056A1 (en) | 2024-01-04 |
| WO2022269543A2 (en) | 2022-12-29 |
| US12227797B2 (en) | 2025-02-18 |
| US20240287587A1 (en) | 2024-08-29 |
| EP4337788B1 (en) | 2024-10-30 |
| CA3223257A1 (en) | 2022-12-29 |
| EP4337788A2 (en) | 2024-03-20 |
| WO2022269543A3 (en) | 2023-02-02 |
| EP4502179A2 (en) | 2025-02-05 |
| JP2024527509A (en) | 2024-07-25 |
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