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EP4271213A4 - COMPOSITIONS AND METHODS OF SUBLINGUAL ADMINISTRATION OF NICOTINE - Google Patents

COMPOSITIONS AND METHODS OF SUBLINGUAL ADMINISTRATION OF NICOTINE Download PDF

Info

Publication number
EP4271213A4
EP4271213A4 EP23723800.1A EP23723800A EP4271213A4 EP 4271213 A4 EP4271213 A4 EP 4271213A4 EP 23723800 A EP23723800 A EP 23723800A EP 4271213 A4 EP4271213 A4 EP 4271213A4
Authority
EP
European Patent Office
Prior art keywords
nicotine
compositions
methods
sublingual administration
sublingual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23723800.1A
Other languages
German (de)
French (fr)
Other versions
EP4271213A1 (en
Inventor
John Docherty
Andrew BUNKA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poviva Corp
Original Assignee
Poviva Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/700,646 external-priority patent/US20230301341A1/en
Priority claimed from US17/700,628 external-priority patent/US11700875B1/en
Application filed by Poviva Corp filed Critical Poviva Corp
Priority claimed from PCT/US2023/015626 external-priority patent/WO2023183227A1/en
Publication of EP4271213A1 publication Critical patent/EP4271213A1/en
Publication of EP4271213A4 publication Critical patent/EP4271213A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP23723800.1A 2022-03-22 2023-03-20 COMPOSITIONS AND METHODS OF SUBLINGUAL ADMINISTRATION OF NICOTINE Pending EP4271213A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17/700,646 US20230301341A1 (en) 2022-03-22 2022-03-22 Compositions and methods for sublingual delivery of nicotine
US17/700,628 US11700875B1 (en) 2022-03-22 2022-03-22 Compositions and methods for sublingual delivery of nicotine
PCT/US2023/015626 WO2023183227A1 (en) 2022-03-22 2023-03-20 Compositions and methods for sublingual delivery of nicotine

Publications (2)

Publication Number Publication Date
EP4271213A1 EP4271213A1 (en) 2023-11-08
EP4271213A4 true EP4271213A4 (en) 2024-08-28

Family

ID=88069090

Family Applications (1)

Application Number Title Priority Date Filing Date
EP23723800.1A Pending EP4271213A4 (en) 2022-03-22 2023-03-20 COMPOSITIONS AND METHODS OF SUBLINGUAL ADMINISTRATION OF NICOTINE

Country Status (5)

Country Link
EP (1) EP4271213A4 (en)
JP (1) JP2024514732A (en)
AU (1) AU2023238723A1 (en)
CA (1) CA3196913A1 (en)
MX (1) MX2023009659A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE540813C2 (en) * 2017-04-24 2018-11-20 Swedish Match North Europe Ab A flavoured moist oral pouched nicotine product comprising
WO2018233795A1 (en) * 2017-06-23 2018-12-27 Fertin Pharma A/S Nicotine pouch
WO2020244721A1 (en) * 2019-06-07 2020-12-10 Ncp Nextgen A/S Nicotine pouch composition and pouch comprising such
US20210345656A1 (en) * 2017-12-08 2021-11-11 Fertin Pharma A/S High nicotine absorption

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE540813C2 (en) * 2017-04-24 2018-11-20 Swedish Match North Europe Ab A flavoured moist oral pouched nicotine product comprising
WO2018233795A1 (en) * 2017-06-23 2018-12-27 Fertin Pharma A/S Nicotine pouch
US20210345656A1 (en) * 2017-12-08 2021-11-11 Fertin Pharma A/S High nicotine absorption
WO2020244721A1 (en) * 2019-06-07 2020-12-10 Ncp Nextgen A/S Nicotine pouch composition and pouch comprising such

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2023183227A1 *

Also Published As

Publication number Publication date
AU2023238723A1 (en) 2024-08-15
MX2023009659A (en) 2023-10-13
CA3196913A1 (en) 2023-09-22
JP2024514732A (en) 2024-04-03
EP4271213A1 (en) 2023-11-08

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: BUNKA, ANDREW

Inventor name: DOCHERTY, JOHN

A4 Supplementary search report drawn up and despatched

Effective date: 20240731

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 9/14 20060101ALI20240725BHEP

Ipc: A24B 13/00 20060101ALI20240725BHEP

Ipc: A24B 15/28 20060101ALI20240725BHEP

Ipc: A61K 31/465 20060101ALI20240725BHEP

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