EP4199921A4 - SOLID ORAL COMPOSITION CONTAINING ELTROMBOPAG-CHOLINE - Google Patents

SOLID ORAL COMPOSITION CONTAINING ELTROMBOPAG-CHOLINE Download PDF

Info

Publication number: EP4199921A4
Authority: EP; European Patent Office
Prior art keywords: choline; composition containing; oral composition; solid oral; containing eltrombopag
Prior art date: 2020-08-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP21858732.7A

Other languages

German (de)

French (fr)

Other versions

EP4199921A1 (en

Inventor

Fatih Sunel

Gulcin TOK

Bulent DEMIR

Selin KOKSAL UZUN

Salih Sermet BASARAN

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanovel Ilac Sanayi ve Ticaret AS

Original Assignee

Sanovel Ilac Sanayi ve Ticaret AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2020-08-21

Filing date

2021-08-13

Publication date

2024-09-25

2021-08-13 Application filed by Sanovel Ilac Sanayi ve Ticaret AS filed Critical Sanovel Ilac Sanayi ve Ticaret AS

2023-06-28 Publication of EP4199921A1 publication Critical patent/EP4199921A1/en

2024-09-25 Publication of EP4199921A4 publication Critical patent/EP4199921A4/en

Status Pending legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP21858732.7A 2020-08-21 2021-08-13 SOLID ORAL COMPOSITION CONTAINING ELTROMBOPAG-CHOLINE Pending EP4199921A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
TR2020/13232A TR202013232A2 (en)	2020-08-21	2020-08-21	Solid oral composition containing eltrombopag choline
PCT/TR2021/050799 WO2022039701A1 (en)	2020-08-21	2021-08-13	A solid oral composition comprising eltrombopag choline

Publications (2)

Publication Number	Publication Date
EP4199921A1 EP4199921A1 (en)	2023-06-28
EP4199921A4 true EP4199921A4 (en)	2024-09-25

Family

ID=80323655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP21858732.7A Pending EP4199921A4 (en)	2020-08-21	2021-08-13	SOLID ORAL COMPOSITION CONTAINING ELTROMBOPAG-CHOLINE

Country Status (3)

Country	Link
EP (1)	EP4199921A4 (en)
TR (1)	TR202013232A2 (en)
WO (1)	WO2022039701A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN117281780B (en) *	2023-11-24	2024-02-02	山东则正医药技术有限公司	Airotopaolamine dry suspension and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2018078644A1 (en) *	2016-10-24	2018-05-03	Hetero Labs Limited	Orally disintegrating tablets of eltrombopag
WO2019071111A1 (en) *	2017-10-06	2019-04-11	Teva Pharmaceuticals Usa, Inc.	Solid state forms of eltrombopag choline
WO2019086725A2 (en) *	2018-03-07	2019-05-09	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Pharmaceutical composition comprising eltrombopag olamine, reducing sugar, and polymeric binder
WO2020055364A2 (en) *	2018-08-02	2020-03-19	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	A pharmaceutical composition comprising eltrombopag olamine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2017042839A1 (en) *	2015-09-08	2017-03-16	Actavis Group Ptc Ehf.	Novel eltrombopag salt and preparation thereof

2020
- 2020-08-21 TR TR2020/13232A patent/TR202013232A2/en unknown
2021
- 2021-08-13 EP EP21858732.7A patent/EP4199921A4/en active Pending
- 2021-08-13 WO PCT/TR2021/050799 patent/WO2022039701A1/en unknown

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2018078644A1 (en) *	2016-10-24	2018-05-03	Hetero Labs Limited	Orally disintegrating tablets of eltrombopag
WO2019071111A1 (en) *	2017-10-06	2019-04-11	Teva Pharmaceuticals Usa, Inc.	Solid state forms of eltrombopag choline
WO2019086725A2 (en) *	2018-03-07	2019-05-09	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Pharmaceutical composition comprising eltrombopag olamine, reducing sugar, and polymeric binder
WO2020055364A2 (en) *	2018-08-02	2020-03-19	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	A pharmaceutical composition comprising eltrombopag olamine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2022039701A1 *

Also Published As

Publication number	Publication date
WO2022039701A1 (en)	2022-02-24
TR202013232A2 (en)	2022-03-21
EP4199921A1 (en)	2023-06-28

Publication	Publication Date	Title
DK4072332T3 (en)	2025-01-20	MOIST, ORAL COMPOSITIONS
EP4227390A4 (en)	2024-10-23	COOLANT-CONTAINING COMPOSITION
EP4148096A4 (en)	2023-11-01	COMPOSITION
EP4279545A4 (en)	2024-11-13	COMPOSITION
EP4094582A4 (en)	2024-02-28	COMPOSITION
EP4321020A4 (en)	2025-05-07	ORAL VACCINE COMPOSITION
EP4328279A4 (en)	2024-10-23	COMPOSITION
EP4112065A4 (en)	2024-04-17	ANTI-TUMOOR COMPOSITION
EP4041238A4 (en)	2024-03-13	ORAL COMPLEMENT FACTOR D INHIBITORS
EP3793609C0 (en)	2023-12-13	ORAL SOLUTION FORMULATION
EP4129275A4 (en)	2023-11-22	COMPOSITION CONTAINING MENTHOL
EP4044996C0 (en)	2023-12-06	ORAL CARE COMPOSITION
EP4054537C0 (en)	2023-06-07	ORAL FORMULATION OF X842
EP3756471A4 (en)	2021-11-10	ORAL INGESTION COMPOSITION
EP3813822A4 (en)	2022-03-16	SOLID ORAL PHARMACEUTICAL COMPOSITIONS CONTAINING TERIFLUNOMIDE
EP4313320A4 (en)	2025-01-01	ANTI-PERSPECTIVE COMPOSITION
EP4288037A4 (en)	2025-01-01	HIGHLY LOADED ORAL FILM FORMULATION
EP4199921A4 (en)	2024-09-25	SOLID ORAL COMPOSITION CONTAINING ELTROMBOPAG-CHOLINE
EP4291042C0 (en)	2024-11-13	OAT-DERIVED COMPOSITION
EP4268816A4 (en)	2024-12-04	ORAL SOLID PREPARATION
DK3706724T3 (en)	2024-10-14	ORAL RIFAMYCIN-SV COMPOSITIONS
EP3836905C0 (en)	2023-10-04	NOVEL ORAL COMPOSITION
EP4330366C0 (en)	2024-09-25	COMPOSITION
EP4259762C0 (en)	2024-06-05	COMPOSITION
EP4062913A4 (en)	2023-01-18	SOLID ORAL FORMULATION OF UTIDELON

Legal Events

Date	Code	Title	Description
2022-02-25	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2023-05-26	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2023-05-26	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2023-06-28	17P	Request for examination filed	Effective date: 20230220
2023-06-28	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2023-08-16	P01	Opt-out of the competence of the unified patent court (upc) registered	Effective date: 20230708
2023-11-29	DAV	Request for validation of the european patent (deleted)
2023-11-29	DAX	Request for extension of the european patent (deleted)
2024-08-21	REG	Reference to a national code	Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0031415200 Ipc: A61K0009200000
2024-09-25	A4	Supplementary search report drawn up and despatched	Effective date: 20240827
2024-09-25	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 9/00 20060101ALI20240821BHEP Ipc: A61P 7/00 20060101ALI20240821BHEP Ipc: A61K 31/4152 20060101ALI20240821BHEP Ipc: A61K 9/20 20060101AFI20240821BHEP
2025-01-01	RAP3	Party data changed (applicant data changed or rights of an application transferred)	Owner name: SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI
2025-01-08	RAP3	Party data changed (applicant data changed or rights of an application transferred)	Owner name: SANOVEL ILAC SANAYI VE TICARET A.S.