EP3947731A4 - Multivalente bindungszusammensetzung zur analyse von nukleinsäuren - Google Patents
Multivalente bindungszusammensetzung zur analyse von nukleinsäuren Download PDFInfo
- Publication number
- EP3947731A4 EP3947731A4 EP20815612.5A EP20815612A EP3947731A4 EP 3947731 A4 EP3947731 A4 EP 3947731A4 EP 20815612 A EP20815612 A EP 20815612A EP 3947731 A4 EP3947731 A4 EP 3947731A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- nucleic acid
- acid analysis
- binding composition
- multivalent binding
- multivalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/157—A reaction step characterised by the number of molecules incorporated or released
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/149—Particles, e.g. beads
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962852876P | 2019-05-24 | 2019-05-24 | |
| US201962897172P | 2019-09-06 | 2019-09-06 | |
| US16/579,794 US10768173B1 (en) | 2019-09-06 | 2019-09-23 | Multivalent binding composition for nucleic acid analysis |
| PCT/US2020/034409 WO2020243017A1 (en) | 2019-05-24 | 2020-05-22 | Multivalent binding composition for nucleic acid analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3947731A1 EP3947731A1 (de) | 2022-02-09 |
| EP3947731A4 true EP3947731A4 (de) | 2022-06-29 |
Family
ID=73554179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20815612.5A Pending EP3947731A4 (de) | 2019-05-24 | 2020-05-22 | Multivalente bindungszusammensetzung zur analyse von nukleinsäuren |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3947731A4 (de) |
| JP (2) | JP7542000B2 (de) |
| KR (3) | KR102823471B1 (de) |
| CN (1) | CN113939601A (de) |
| AU (3) | AU2020285657B2 (de) |
| CA (1) | CA3137120A1 (de) |
| DE (1) | DE112020002516B4 (de) |
| GB (1) | GB2597398B (de) |
| IL (3) | IL316901A (de) |
| SG (1) | SG11202112049VA (de) |
| WO (1) | WO2020243017A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2589496B (en) | 2018-06-12 | 2023-01-25 | Element Biosciences Inc | Improved reverse transcriptase for nucleic acid sequencing |
| US10704094B1 (en) | 2018-11-14 | 2020-07-07 | Element Biosciences, Inc. | Multipart reagents having increased avidity for polymerase binding |
| US10768173B1 (en) | 2019-09-06 | 2020-09-08 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| GB2598656B (en) | 2018-11-15 | 2023-10-04 | Element Biosciences Inc | Methods for generating circular nucleic acid molecules |
| SG11202009968RA (en) | 2018-12-07 | 2020-11-27 | Element Biosciences Inc | Flow cell device and use thereof |
| US12313627B2 (en) | 2019-05-01 | 2025-05-27 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US11053540B1 (en) | 2020-01-17 | 2021-07-06 | Element Biosciences, Inc. | High performance fluorescence imaging module for genomic testing assay |
| US11198121B1 (en) | 2020-06-10 | 2021-12-14 | Element Biosciences, Inc. | Flow cell systems and devices |
| GB2599729A (en) * | 2020-10-12 | 2022-04-13 | Sumitomo Chemical Co | Method comprising light emitting marker |
| GB2617481B (en) | 2020-10-30 | 2025-07-02 | Element Biosciences Inc | Reagents for massively parallel nucleic acid sequencing |
| JP2024530883A (ja) | 2021-07-21 | 2024-08-27 | エレメント バイオサイエンシーズ，インク． | 核酸シーケンシングのための光学システム、およびその方法 |
| KR20230153706A (ko) | 2022-04-29 | 2023-11-07 | 연세대학교 산학협력단 | 핵산의 검출 또는 분리용 조성물 및 이를 이용한 핵산의 검출 또는 분리 방법 |
| CN116024315A (zh) * | 2022-11-30 | 2023-04-28 | 温州医科大学 | 一种基于链置换反应的多价双锁钥系统及其在核苷酸多态性检测中的应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005111240A2 (en) * | 2004-04-30 | 2005-11-24 | Li-Cor, Inc. | Field-switch sequencing |
| WO2009073201A2 (en) * | 2007-12-04 | 2009-06-11 | Pacific Biosciences Of California, Inc. | Alternate labeling strategies for single molecule sequencing |
| US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| WO2006097320A2 (de) * | 2005-03-17 | 2006-09-21 | Genovoxx Gmbh | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
| US8906612B2 (en) * | 2010-08-25 | 2014-12-09 | Pacific Biosciences Of California, Inc. | Scaffold-based polymerase enzyme substrates |
| US20150086981A1 (en) * | 2011-05-04 | 2015-03-26 | Genovoxx Gmbh | Nucleoside-triphosphate conjugate and methods for the use thereof |
| EP3222627B1 (de) * | 2012-02-15 | 2019-08-07 | Pacific Biosciences of California, Inc. | Polymeraseenzymsubstrate mit proteinabschirmung |
| EP3589752B1 (de) | 2017-01-26 | 2021-05-19 | QIAGEN GmbH | Verfahren zur erzeugung einer sequenzierungsbibliothek |
| AU2018214601A1 (en) | 2017-02-02 | 2019-08-15 | Caris Science, Inc. | Targeted oligonucleotides |
-
2020
- 2020-05-22 JP JP2021561845A patent/JP7542000B2/ja active Active
- 2020-05-22 SG SG11202112049VA patent/SG11202112049VA/en unknown
- 2020-05-22 CN CN202080042516.6A patent/CN113939601A/zh active Pending
- 2020-05-22 WO PCT/US2020/034409 patent/WO2020243017A1/en active IP Right Grant
- 2020-05-22 DE DE112020002516.0T patent/DE112020002516B4/de active Active
- 2020-05-22 CA CA3137120A patent/CA3137120A1/en active Pending
- 2020-05-22 EP EP20815612.5A patent/EP3947731A4/de active Pending
- 2020-05-22 GB GB2115667.4A patent/GB2597398B/en active Active
- 2020-05-22 KR KR1020237040302A patent/KR102823471B1/ko active Active
- 2020-05-22 IL IL316901A patent/IL316901A/en unknown
- 2020-05-22 AU AU2020285657A patent/AU2020285657B2/en active Active
- 2020-05-22 IL IL301380A patent/IL301380B2/en unknown
- 2020-05-22 KR KR1020217037728A patent/KR102607124B1/ko active Active
- 2020-05-22 KR KR1020257019970A patent/KR20250096873A/ko active Pending
-
2021
- 2021-10-24 IL IL287528A patent/IL287528B2/en unknown
-
2022
- 2022-12-22 AU AU2022291540A patent/AU2022291540B2/en active Active
-
2024
- 2024-08-16 JP JP2024137063A patent/JP2024174880A/ja active Pending
-
2025
- 2025-01-20 AU AU2025200380A patent/AU2025200380A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
| WO2005111240A2 (en) * | 2004-04-30 | 2005-11-24 | Li-Cor, Inc. | Field-switch sequencing |
| WO2009073201A2 (en) * | 2007-12-04 | 2009-06-11 | Pacific Biosciences Of California, Inc. | Alternate labeling strategies for single molecule sequencing |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO2020243017A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2022291540B2 (en) | 2024-11-14 |
| IL301380B2 (en) | 2025-05-01 |
| EP3947731A1 (de) | 2022-02-09 |
| KR102607124B1 (ko) | 2023-11-29 |
| IL316901A (en) | 2025-01-01 |
| WO2020243017A1 (en) | 2020-12-03 |
| SG11202112049VA (en) | 2021-12-30 |
| GB2597398A (en) | 2022-01-26 |
| CN113939601A (zh) | 2022-01-14 |
| AU2025200380A1 (en) | 2025-02-06 |
| JP2024174880A (ja) | 2024-12-17 |
| IL301380B1 (en) | 2025-01-01 |
| AU2020285657A1 (en) | 2021-11-18 |
| IL301380A (en) | 2023-05-01 |
| AU2022291540A1 (en) | 2023-02-02 |
| KR20250096873A (ko) | 2025-06-27 |
| IL287528A (en) | 2021-12-01 |
| JP7542000B2 (ja) | 2024-08-29 |
| KR20210144929A (ko) | 2021-11-30 |
| DE112020002516T5 (de) | 2022-03-24 |
| KR20230165871A (ko) | 2023-12-05 |
| IL287528B2 (en) | 2023-08-01 |
| GB2597398B (en) | 2024-03-06 |
| GB202115667D0 (en) | 2021-12-15 |
| JP2022535187A (ja) | 2022-08-05 |
| AU2020285657B2 (en) | 2022-10-06 |
| DE112020002516B4 (de) | 2025-03-13 |
| CA3137120A1 (en) | 2020-12-03 |
| IL287528B1 (en) | 2023-04-01 |
| KR102823471B1 (ko) | 2025-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
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| 17P | Request for examination filed |
Effective date: 20211025 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20220601 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/6869 20180101AFI20220525BHEP |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40068615 Country of ref document: HK |
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| RAP3 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: ELEMENT BIOSCIENCES, INC. |