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EP3846820A4 - Cyclic sulfamide compounds for treatment of hbv - Google Patents

Cyclic sulfamide compounds for treatment of hbv Download PDF

Info

Publication number
EP3846820A4
EP3846820A4 EP19858180.3A EP19858180A EP3846820A4 EP 3846820 A4 EP3846820 A4 EP 3846820A4 EP 19858180 A EP19858180 A EP 19858180A EP 3846820 A4 EP3846820 A4 EP 3846820A4
Authority
EP
European Patent Office
Prior art keywords
hbv
treatment
sulfamide compounds
cyclic sulfamide
cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19858180.3A
Other languages
German (de)
French (fr)
Other versions
EP3846820A1 (en
Inventor
Michael Walker
Leping Li
Simon Nicolas Haydar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Assembly Biosciences Inc
Original Assignee
Assembly Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assembly Biosciences Inc filed Critical Assembly Biosciences Inc
Publication of EP3846820A1 publication Critical patent/EP3846820A1/en
Publication of EP3846820A4 publication Critical patent/EP3846820A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19858180.3A 2018-09-05 2019-09-05 Cyclic sulfamide compounds for treatment of hbv Withdrawn EP3846820A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862727274P 2018-09-05 2018-09-05
PCT/US2019/049730 WO2020051320A1 (en) 2018-09-05 2019-09-05 Cyclic sulfamide compounds for treatment of hbv

Publications (2)

Publication Number Publication Date
EP3846820A1 EP3846820A1 (en) 2021-07-14
EP3846820A4 true EP3846820A4 (en) 2022-01-19

Family

ID=69722738

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19858180.3A Withdrawn EP3846820A4 (en) 2018-09-05 2019-09-05 Cyclic sulfamide compounds for treatment of hbv

Country Status (4)

Country Link
US (1) US20230075856A1 (en)
EP (1) EP3846820A4 (en)
CN (1) CN113164493A (en)
WO (1) WO2020051320A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021213445A1 (en) * 2020-04-22 2021-10-28 南京明德新药研发有限公司 Sultam derivatives and application thereof
CN117337286A (en) * 2021-05-07 2024-01-02 南京明德新药研发有限公司 Methylsulfonyl urea compound and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018011163A1 (en) * 2016-07-14 2018-01-18 F. Hoffmann-La Roche Ag 6,7-dihydro-4h-pyrazolo[1,5-a]pyrazine and 6,7-dihydro-4h-triazolo[1,5-a]pyrazine compounds for the treatment of infectious diseases
WO2018160878A1 (en) * 2017-03-02 2018-09-07 Assembly Biosciences, Inc. Cyclic sulfamide compounds and methods of using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ610331A (en) * 2010-10-20 2015-01-30 Biota Scient Management Viral polymerase inhibitors
WO2020051319A1 (en) * 2018-09-05 2020-03-12 Assembly Biosciences, Inc. Cyclic sulfamide compounds for treatment of hbv

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018011163A1 (en) * 2016-07-14 2018-01-18 F. Hoffmann-La Roche Ag 6,7-dihydro-4h-pyrazolo[1,5-a]pyrazine and 6,7-dihydro-4h-triazolo[1,5-a]pyrazine compounds for the treatment of infectious diseases
WO2018160878A1 (en) * 2017-03-02 2018-09-07 Assembly Biosciences, Inc. Cyclic sulfamide compounds and methods of using same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020051320A1 *

Also Published As

Publication number Publication date
US20230075856A1 (en) 2023-03-09
CN113164493A (en) 2021-07-23
EP3846820A1 (en) 2021-07-14
WO2020051320A1 (en) 2020-03-12

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Owner name: ASSEMBLY BIOSCIENCES, INC.

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