EP3322823A4 - METHOD FOR DIAGNOSING, PROGNOSIS AND MONITORING BREAST CANCER AND REAGENTS THEREFOR - Google Patents

METHOD FOR DIAGNOSING, PROGNOSIS AND MONITORING BREAST CANCER AND REAGENTS THEREFOR Download PDF

Info

Publication number: EP3322823A4
Authority: EP; European Patent Office
Prior art keywords: prognosis; diagnosing; breast cancer; monitoring breast; reagents therefor
Prior art date: 2015-07-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP16823558.8A

Other languages

German (de)

French (fr)

Other versions

EP3322823A1 (en

Inventor

Andrew Stone

Elena ZOTENKO

Susan Clark

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Garvan Institute of Medical Research

Original Assignee

Garvan Institute of Medical Research

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-07-14

Filing date

2016-07-14

Publication date

2019-06-19

2016-07-14 Application filed by Garvan Institute of Medical Research filed Critical Garvan Institute of Medical Research

2018-05-23 Publication of EP3322823A1 publication Critical patent/EP3322823A1/en

2019-06-19 Publication of EP3322823A4 publication Critical patent/EP3322823A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
Analytical Chemistry (AREA)
Genetics & Genomics (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Pathology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP16823558.8A 2015-07-14 2016-07-14 METHOD FOR DIAGNOSING, PROGNOSIS AND MONITORING BREAST CANCER AND REAGENTS THEREFOR Withdrawn EP3322823A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201562192540P	2015-07-14	2015-07-14
PCT/AU2016/050615 WO2017008117A1 (en)	2015-07-14	2016-07-14	Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor

Publications (2)

Publication Number	Publication Date
EP3322823A1 EP3322823A1 (en)	2018-05-23
EP3322823A4 true EP3322823A4 (en)	2019-06-19

Family

ID=57756617

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP16823558.8A Withdrawn EP3322823A4 (en)	2015-07-14	2016-07-14	METHOD FOR DIAGNOSING, PROGNOSIS AND MONITORING BREAST CANCER AND REAGENTS THEREFOR

Country Status (4)

Country	Link
EP (1)	EP3322823A4 (en)
CN (1)	CN107922977A (en)
AU (1)	AU2016293381A1 (en)
WO (1)	WO2017008117A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN108676879A (en) *	2018-05-24	2018-10-19	中国科学院北京基因组研究所	Application of specific methylation sites as diagnostic markers for molecular typing of breast cancer
US20210230662A1 (en) *	2018-10-14	2021-07-29	Lantern Pharma Inc.	Methods for the Treatment of Solid Tumor Cancers Using Illudins and Biomarkers
WO2020252721A1 (en) *	2019-06-20	2020-12-24	The Johns Hopkins University	Dna methylation markers and their use in differentiation of suspected cancerous lymph node biopsy samples
WO2021174262A1 (en) *	2020-02-28	2021-09-02	Loma Linda University	Methods of evaluating breast cancer prognosis and treatment regimens based on methylation status of the ins-igf2 region
CN111235241A (en) *	2020-03-30	2020-06-05	陕西科技大学	FOXA1 gene methylation detection kit based on pyrosequencing technology and detection method
CN111349695A (en) *	2020-03-30	2020-06-30	陕西科技大学	GATA3 gene methylation detection kit based on pyrosequencing technology and detection method
WO2022000399A1 (en) *	2020-07-02	2022-01-06	The Johns Hopkins University	Methylated markers for accurate detection of primary central nervous system and systemic diffuse large b cell lymphoma
WO2022123419A1 (en) *	2020-12-08	2022-06-16	Pfizer Inc.	Treatment of luminal subtypes of hr-positive, her2-negative early breast cancer with palbociclib
CN114480652A (en) *	2022-02-21	2022-05-13	深圳市陆为生物技术有限公司	Products to evaluate responsiveness of breast cancer patients to adjuvant endocrine therapy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003000189A2 (en) *	2001-06-21	2003-01-03	Baylor College Of Medicine	Prediction, diagnosis and treatment of endocrine resistant breast cancer, using p38 mapk pathway
WO2006004597A2 (en) *	2004-06-01	2006-01-12	University Of Southern California	Association of breast cancer dna methylation profiles with hormone receptor status and response to tamoxifen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2012098215A1 (en) *	2011-01-20	2012-07-26	Université Libre de Bruxelles	Epigenetic portraits of human breast cancers

2016
- 2016-07-14 EP EP16823558.8A patent/EP3322823A4/en not_active Withdrawn
- 2016-07-14 AU AU2016293381A patent/AU2016293381A1/en not_active Abandoned
- 2016-07-14 WO PCT/AU2016/050615 patent/WO2017008117A1/en active Application Filing
- 2016-07-14 CN CN201680051447.9A patent/CN107922977A/en active Pending

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003000189A2 (en) *	2001-06-21	2003-01-03	Baylor College Of Medicine	Prediction, diagnosis and treatment of endocrine resistant breast cancer, using p38 mapk pathway
WO2006004597A2 (en) *	2004-06-01	2006-01-12	University Of Southern California	Association of breast cancer dna methylation profiles with hormone receptor status and response to tamoxifen

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CAROLYN L SMITH ET AL: "Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence", BREAST CANCER RESEARCH AND TREATMENT, KLUWER ACADEMIC PUBLISHERS, BO, vol. 136, no. 1, 27 September 2012 (2012-09-27), pages 253 - 265, XP035125727, ISSN: 1573-7217, DOI: 10.1007/S10549-012-2262-7 *
K W MERRELL ET AL: "Differential recruitment of nuclear receptor coregulators in ligand-dependent transcriptional repression by estrogen receptor-[alpha]", ONCOGENE, vol. 30, no. 13, 22 November 2010 (2010-11-22), London, pages 1608 - 1614, XP055587477, ISSN: 0950-9232, DOI: 10.1038/onc.2010.528 *
L. ZHANG ET AL: "SpliceArray Profiling of Breast Cancer Reveals a Novel Variant of NCOR2/SMRT That Is Associated with Tamoxifen Resistance and Control of ER? Transcriptional Activity", CANCER RESEARCH, vol. 73, no. 1, 1 November 2012 (2012-11-01), Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, pages 246 - 255, XP055367636, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-12-2241 *
RYO AKIHIDE ET AL: "Pinning down HER2-ER crosstalk in SMRT regulation.", TRENDS IN BIOCHEMICAL SCIENCES APR 2009, vol. 34, no. 4, April 2009 (2009-04-01), pages 162 - 165, XP002791216, ISSN: 0968-0004 *
See also references of WO2017008117A1 *
T VAN AGTHOVEN ET AL: "CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer", BRITISH JOURNAL OF CANCER, vol. 101, no. 11, 10 November 2009 (2009-11-10), GB, pages 1824 - 1832, XP055587459, ISSN: 0007-0920, DOI: 10.1038/sj.bjc.6605423 *

Also Published As

Publication number	Publication date
CN107922977A (en)	2018-04-17
WO2017008117A1 (en)	2017-01-19
AU2016293381A1 (en)	2018-01-25
EP3322823A1 (en)	2018-05-23

Publication	Publication Date	Title
EP3322823A4 (en)	2019-06-19	METHOD FOR DIAGNOSING, PROGNOSIS AND MONITORING BREAST CANCER AND REAGENTS THEREFOR
EP3685137C0 (en)	2023-12-20	SYSTEM AND METHOD FOR AUTOMATED FAULT DIAGNOSIS AND PROGNOSIS FOR ROTARY EQUIPMENT
EP3333660A4 (en)	2019-04-03	ANOMALY PREDICTOR DIAGNOSIS SYSTEM AND ANOMALY PREDICTOR DIAGNOSIS METHOD
AU2015318823A1 (en)	2016-03-24	Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor
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FR3028068B1 (en)	2016-12-02	METHOD, EQUIPMENT AND SYSTEM FOR ASSISTING DIAGNOSIS
EP3292218A4 (en)	2019-01-16	Compositions and methods for monitoring, diagnosis, prognosis, detection, and treatment of cancer
EP3415914A4 (en)	2019-10-23	METHOD, BIOMARKER AND DIAGNOSTIC AGENT FOR DETECTING HIGH-RISK PROSTATE CANCER
KR101942197B9 (en)	2023-06-09	Prostate disease diagnosis method through bacterial metagenome analysis

Legal Events

Date	Code	Title	Description
2017-01-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2018-04-20	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2018-04-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2018-05-23	17P	Request for examination filed	Effective date: 20180205
2018-05-23	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2018-05-23	AX	Request for extension of the european patent	Extension state: BA ME
2018-10-24	DAV	Request for validation of the european patent (deleted)
2018-10-24	DAX	Request for extension of the european patent (deleted)
2019-06-19	A4	Supplementary search report drawn up and despatched	Effective date: 20190522
2019-06-19	RIC1	Information provided on ipc code assigned before grant	Ipc: C12Q 1/48 20060101ALI20190514BHEP Ipc: C12Q 1/68 20180101AFI20190514BHEP Ipc: G01N 33/574 20060101ALI20190514BHEP
2020-07-10	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2020-08-12	18D	Application deemed to be withdrawn	Effective date: 20191218