EP3307913A4 - METHODS OF DIAGNOSING AND TREATING AUTISM - Google Patents
METHODS OF DIAGNOSING AND TREATING AUTISM Download PDFInfo
- Publication number
- EP3307913A4 EP3307913A4 EP16812321.4A EP16812321A EP3307913A4 EP 3307913 A4 EP3307913 A4 EP 3307913A4 EP 16812321 A EP16812321 A EP 16812321A EP 3307913 A4 EP3307913 A4 EP 3307913A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- diagnosing
- methods
- treating autism
- autism
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/740,230 US11219617B2 (en) | 2014-05-30 | 2015-06-15 | Methods of diagnosing and treating autism |
US201562215673P | 2015-09-08 | 2015-09-08 | |
US201562215636P | 2015-09-08 | 2015-09-08 | |
US201562215628P | 2015-09-08 | 2015-09-08 | |
US201562215633P | 2015-09-08 | 2015-09-08 | |
PCT/US2016/037596 WO2016205348A1 (en) | 2015-06-15 | 2016-06-15 | Methods of diagnosing and treating autism |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3307913A1 EP3307913A1 (en) | 2018-04-18 |
EP3307913A4 true EP3307913A4 (en) | 2019-03-27 |
Family
ID=57546224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16812321.4A Withdrawn EP3307913A4 (en) | 2015-06-15 | 2016-06-15 | METHODS OF DIAGNOSING AND TREATING AUTISM |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP3307913A4 (en) |
CN (1) | CN108474036A (en) |
AU (1) | AU2016278053A1 (en) |
CA (1) | CA2989326A1 (en) |
WO (1) | WO2016205348A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6216486B2 (en) | 2010-08-24 | 2017-10-18 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia | Association of low-frequency recurrent genetic variation with attention-deficit / hyperactivity disorder and its use for diagnosis and treatment |
DK3347014T3 (en) | 2015-09-08 | 2021-12-06 | Childrens Hospital Philadelphia | Methods for diagnosing and treating Tourette's syndrome |
US11684617B2 (en) | 2017-04-19 | 2023-06-27 | The Children's Hospital Of Philadelphia | Methods of diagnosing and treating ADHD in biomarker positive subjects |
CN109813912B (en) * | 2019-01-04 | 2021-12-28 | 深圳大学 | Application of group of serum differential protein combinations in preparation of reagent for detecting autism |
KR102639856B1 (en) * | 2020-10-14 | 2024-02-23 | 한국원자력의학원 | Biomarker composition for predicting brain diseases prognosis induced by microplastic exposure and method for predicting prognosis using the same |
CN113706458B (en) * | 2021-07-15 | 2023-03-28 | 电子科技大学 | Autism detection device based on Gossip model |
CN114446476B (en) * | 2022-01-28 | 2023-02-17 | 中南大学湘雅二医院 | Construction method, prediction method and device of autism treatment effect prediction model |
CN119044511B (en) * | 2024-11-01 | 2025-01-28 | 中日友好医院(中日友好临床医学研究所) | Biomarker for early diagnosis of DKD (DKD), analysis method, kit and application |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US20140315992A1 (en) * | 2011-07-07 | 2014-10-23 | The Children's Hospital Of Philadelphia | Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1202962A (en) | 1982-10-19 | 1986-04-08 | David P. Clifford | Substituted n-phenyl-n'-benzoyl ureas and their use as insecticides and acaricides |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
FR2597100A1 (en) | 1986-01-21 | 1987-10-16 | Nippon Shinyaku Co Ltd | PYROGLUTAMIDE DERIVATIVES |
US20140216734A1 (en) * | 2013-02-05 | 2014-08-07 | Schlumberger Technology Corporation | Casing collar location using elecromagnetic wave phase shift measurement |
WO2014152965A2 (en) * | 2013-03-14 | 2014-09-25 | The Children's Hospital Of Philadelphia | Schizophrenia-associated genetic loci identified in genome wide association studies and use thereof as novel therapeutic targets |
-
2016
- 2016-06-15 AU AU2016278053A patent/AU2016278053A1/en not_active Abandoned
- 2016-06-15 CN CN201680048195.4A patent/CN108474036A/en active Pending
- 2016-06-15 EP EP16812321.4A patent/EP3307913A4/en not_active Withdrawn
- 2016-06-15 WO PCT/US2016/037596 patent/WO2016205348A1/en unknown
- 2016-06-15 CA CA2989326A patent/CA2989326A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US20140315992A1 (en) * | 2011-07-07 | 2014-10-23 | The Children's Hospital Of Philadelphia | Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism |
Non-Patent Citations (3)
Title |
---|
GREGORY KAREN J ET AL: "Pharmacology of metabotropic glutamate receptor allosteric modulators: structural basis and therapeutic potential for CNS disorders", PROGRESS IN MOLECULAR BIOLOGY AND TRANSLATIONAL SCI, ELSEVIER, NL, vol. 115, 1 January 2013 (2013-01-01), pages 61 - 121, XP009192627, ISSN: 1878-0814, DOI: 10.1016/B978-0-12-394587-7.00002-6 * |
MALYKH ANDREI G ET AL: "Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders", DRUGS, SPRINGER INTERNATIONAL PUBLISHING, vol. 70, no. 3, 1 January 2010 (2010-01-01), pages 287 - 312, XP009162620, ISSN: 0012-6667, DOI: 10.2165/11319230-000000000-00000 * |
See also references of WO2016205348A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP3307913A1 (en) | 2018-04-18 |
CN108474036A (en) | 2018-08-31 |
CA2989326A1 (en) | 2016-12-22 |
WO2016205348A1 (en) | 2016-12-22 |
AU2016278053A1 (en) | 2018-01-04 |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: GLESSNER, JOSEPH Inventor name: WENGER, TARA Inventor name: HAKONARSON, HAKON Inventor name: HADLEY, DEXTER Inventor name: WU, ZHI-LIANG Inventor name: KAO, CHARLLY |
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Effective date: 20190225 |
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Ipc: A61P 25/00 20060101ALI20190219BHEP Ipc: C12Q 1/68 20180101ALI20190219BHEP Ipc: A61K 31/454 20060101AFI20190219BHEP Ipc: G01N 33/68 20060101ALI20190219BHEP |
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