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EP3277831A4 - Biosensor system for the rapid detection of analytes - Google Patents

Biosensor system for the rapid detection of analytes Download PDF

Info

Publication number
EP3277831A4
EP3277831A4 EP16774179.2A EP16774179A EP3277831A4 EP 3277831 A4 EP3277831 A4 EP 3277831A4 EP 16774179 A EP16774179 A EP 16774179A EP 3277831 A4 EP3277831 A4 EP 3277831A4
Authority
EP
European Patent Office
Prior art keywords
analytes
rapid detection
biosensor system
biosensor
rapid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16774179.2A
Other languages
German (de)
French (fr)
Other versions
EP3277831A2 (en
Inventor
Thomas J. Zupancic
Lingchun ZENG
Srikanth Vedamoorthy
Joel S. LWANDE
Joseph D. Kittle
Min MO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fundamental Solutions Corp
Original Assignee
Fundamental Solutions Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundamental Solutions Corp filed Critical Fundamental Solutions Corp
Priority to EP18180720.7A priority Critical patent/EP3404410B1/en
Priority to EP18209257.7A priority patent/EP3470527A1/en
Priority to EP18180727.2A priority patent/EP3404412A3/en
Priority to EP18180724.9A priority patent/EP3404411A3/en
Publication of EP3277831A2 publication Critical patent/EP3277831A2/en
Publication of EP3277831A4 publication Critical patent/EP3277831A4/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/22Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a Strep-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP16774179.2A 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes Pending EP3277831A4 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP18180720.7A EP3404410B1 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18209257.7A EP3470527A1 (en) 2015-03-31 2016-03-31 Chimeric fusion protein fcgammari-igm
EP18180727.2A EP3404412A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180724.9A EP3404411A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562140920P 2015-03-31 2015-03-31
PCT/US2016/025219 WO2016161088A2 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes

Related Child Applications (8)

Application Number Title Priority Date Filing Date
EP18209257.7A Division EP3470527A1 (en) 2015-03-31 2016-03-31 Chimeric fusion protein fcgammari-igm
EP18209257.7A Division-Into EP3470527A1 (en) 2015-03-31 2016-03-31 Chimeric fusion protein fcgammari-igm
EP18180720.7A Division EP3404410B1 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180720.7A Division-Into EP3404410B1 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180727.2A Division EP3404412A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180727.2A Division-Into EP3404412A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180724.9A Division EP3404411A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180724.9A Division-Into EP3404411A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes

Publications (2)

Publication Number Publication Date
EP3277831A2 EP3277831A2 (en) 2018-02-07
EP3277831A4 true EP3277831A4 (en) 2019-01-09

Family

ID=57007336

Family Applications (5)

Application Number Title Priority Date Filing Date
EP18209257.7A Withdrawn EP3470527A1 (en) 2015-03-31 2016-03-31 Chimeric fusion protein fcgammari-igm
EP16774179.2A Pending EP3277831A4 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180724.9A Pending EP3404411A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180720.7A Active EP3404410B1 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180727.2A Pending EP3404412A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18209257.7A Withdrawn EP3470527A1 (en) 2015-03-31 2016-03-31 Chimeric fusion protein fcgammari-igm

Family Applications After (3)

Application Number Title Priority Date Filing Date
EP18180724.9A Pending EP3404411A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180720.7A Active EP3404410B1 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes
EP18180727.2A Pending EP3404412A3 (en) 2015-03-31 2016-03-31 Biosensor system for the rapid detection of analytes

Country Status (9)

Country Link
EP (5) EP3470527A1 (en)
JP (1) JP6828005B2 (en)
KR (1) KR102540406B1 (en)
CN (1) CN107429286A (en)
CA (1) CA2982133C (en)
ES (1) ES2893879T3 (en)
IL (1) IL254687B2 (en)
RU (1) RU2717658C2 (en)
WO (1) WO2016161088A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL267568B2 (en) * 2016-12-22 2023-04-01 Fundamental Solutions Corp Universal biosensor system for analyte detection
US10613083B2 (en) 2016-12-22 2020-04-07 Fundamental Solutions Corporation Universal biosensor system for analyte detection
WO2019076262A1 (en) * 2017-10-18 2019-04-25 深圳华大生命科学研究院 Biosensor for detecting target molecular compound, and system comprising biosensor
KR20210018196A (en) * 2018-03-15 2021-02-17 펀다멘탈 솔류션스 코포레이션 Programmable immune cell receptor complex system
EP3870973A4 (en) * 2018-10-25 2022-04-13 The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organization (ARO) (Volcani Center) MEANS AND METHODS OF ANALYZING LIQUID SAMPLES AT THE POINT OF SUPPLY
CN113214374B (en) * 2020-02-06 2022-08-26 深圳华大基因股份有限公司 Echinococcosis new antigen Cystatin protein
CN113050547B (en) * 2021-03-04 2022-03-25 宏晶微电子科技股份有限公司 Test stimulus generation method, test method, electronic device, and storage medium
KR102625649B1 (en) 2022-12-13 2024-01-17 주식회사 다이아슈어바이오 Electrochemical detection method of nucleic acid using signal transmitter in polymerase chain reaction
KR102695332B1 (en) 2022-12-16 2024-08-16 주식회사 다이아슈어바이오 Enzyme-substrate reaction-based biosensor for component detection of biological analytes and detection method using the same

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WO2002020038A2 (en) * 2000-09-06 2002-03-14 Pharmexa A/S Method for down-regulating ige
WO2013019615A2 (en) * 2011-07-29 2013-02-07 The Trustees Of The University Of Pennsylvania Switch costimulatory receptors
WO2013116287A1 (en) * 2012-01-31 2013-08-08 Genentech, Inc. Anti-ig-e m1' antibodies and methods using same
US20140273020A1 (en) * 2013-03-13 2014-09-18 Applied Biomolecular Technologies System for rapidly detecting infectious agents using a hybridoma-based biosensor

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DAVID L PORTER ET AL: "Chimeric Antigen Receptor Therapy for B-cell Malignancies", JOURNAL OF CANCER, vol. 2042127, 1 January 2011 (2011-01-01), AU, pages 331, XP055247868, ISSN: 1837-9664, DOI: 10.7150/jca.2.331 *
JONATHAN T. SOCKOLOSKY ET AL: "Fusion of a Short Peptide that Binds Immunoglobulin G to a Recombinant Protein Substantially Increases Its Plasma Half-Life in Mice", PLOS ONE, vol. 9, no. 7, 24 July 2014 (2014-07-24), pages e102566, XP055490311, DOI: 10.1371/journal.pone.0102566 *
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Also Published As

Publication number Publication date
EP3404411A2 (en) 2018-11-21
EP3404410B1 (en) 2021-07-14
EP3404410A3 (en) 2019-01-30
CA2982133A1 (en) 2016-10-06
JP2018516590A (en) 2018-06-28
KR102540406B1 (en) 2023-06-09
EP3404412A3 (en) 2019-02-13
IL254687A0 (en) 2017-11-30
EP3470527A1 (en) 2019-04-17
EP3404412A2 (en) 2018-11-21
RU2017129911A (en) 2019-05-06
CA2982133C (en) 2022-05-03
KR20170132861A (en) 2017-12-04
EP3277831A2 (en) 2018-02-07
EP3404410A2 (en) 2018-11-21
ES2893879T3 (en) 2022-02-10
WO2016161088A3 (en) 2016-11-24
RU2017129911A3 (en) 2020-01-27
WO2016161088A2 (en) 2016-10-06
IL254687B2 (en) 2024-01-01
CN107429286A (en) 2017-12-01
EP3404411A3 (en) 2019-02-13
IL254687B1 (en) 2023-09-01
JP6828005B2 (en) 2021-02-10
RU2717658C2 (en) 2020-03-24

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