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EP3083032B1 - Method for operating a production plant of modular design - Google Patents

Method for operating a production plant of modular design Download PDF

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Publication number
EP3083032B1
EP3083032B1 EP14821573.4A EP14821573A EP3083032B1 EP 3083032 B1 EP3083032 B1 EP 3083032B1 EP 14821573 A EP14821573 A EP 14821573A EP 3083032 B1 EP3083032 B1 EP 3083032B1
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EP
European Patent Office
Prior art keywords
process module
production
amount
processed
modules
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EP14821573.4A
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German (de)
French (fr)
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EP3083032A1 (en
Inventor
Achim KÜPPER
Stefan Ochs
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Bayer AG
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Bayer AG
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Publication of EP3083032A1 publication Critical patent/EP3083032A1/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/004—Multifunctional apparatus for automatic manufacturing of various chemical products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/0033—Optimalisation processes, i.e. processes with adaptive control systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00162—Controlling or regulating processes controlling the pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00164—Controlling or regulating processes controlling the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00182—Controlling or regulating processes controlling the level of reactants in the reactor vessel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P90/00—Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
    • Y02P90/02—Total factory control, e.g. smart factories, flexible manufacturing systems [FMS] or integrated manufacturing systems [IMS]

Definitions

  • the invention relates to a method for operating a production system which is connected to one another in terms of production technology and has control technology-independent process modules for the production of a chemical and / or pharmaceutical product.
  • the invention relates to a production plant for the production of a chemical and / or pharmaceutical product.
  • the document EP 1 932 828 A2 describes a method for operating a process module within a production plant and the corresponding production plant.
  • the mass flow into the process module or mass flow from the process module is increased or decreased if the amount of material present in this process module to be processed by this process module is less than or greater than a quantity limit.
  • the document US 4,332,590 A describes a very similar process for operating a process module within a production plant as well as the corresponding production plant.
  • a production plant can be built up modularly from individual process modules that can be connected to one another in terms of process technology and are autonomous in terms of control technology.
  • production plants require new types of control concepts, since control concepts used in conventional production plants are not readily transferable to production plants which are modularly constructed from process technology-independent process modules.
  • a mass flow from the respective process module is increased, if the amount of material to be processed by this process module that is present in this process module is greater than the quantity limit, whereby the mass flow is at the same time a mass inflow of a further process module immediately downstream in production technology, the production system or Their process modules according to a control concept, also known from manufacturing technology, the so-called push principle.
  • the impulse for the activity therefore originates from a process module which is respectively connected downstream of a process module, whereas with the push principle the impulse of activity originates from a process module which is respectively connected upstream of a process module. It is essential for the invention that all process modules of a production plant work uniformly according to the pull principle or the push principle.
  • the process modules which can be connected to one another in terms of production technology and are autonomous in terms of control technology, can be designed as transportable units as a whole, which can be transported to a desired production location at which a suitably equipped, modularly constructed production system is to be set up, or can be transported away from this location after completion of the desired production .
  • a process module can have a housing that enables easy transportation of the process module, in which at least one process unit can be arranged and the dimensions of which can be standardized in order to carry out the desired process section.
  • the process modules can be connected to a permanently installed communication network and to a supply network with which the process modules can be supplied with substance and / or energy and / or released into the substance, so that by means of the process modules essentially self-sufficient at least one chemical batch reaction and / or continuous production can be carried out.
  • solid, liquid and / or gaseous substances or mixtures of substances which can be single-phase or multi-phase, for example as a suspension or emulsion can be transported via the supply network.
  • the supply network can include a compressed air line for the supply of compressed air, a feed water line for the supply of water, an electric line for the supply of electrical energy, a material line for the supply of starting materials and / or auxiliary materials and / or for the removal of products, by-products and / or waste materials, have a cooling line for supplying cold or for removing heat and / or a heating line for supplying heat or for removing cold.
  • Various wired or wireless communication networks can be considered as the communication network. A standardized exchange of information between the process modules connected to the communication network can take place via the communication network.
  • a storage for substance and / or energy and / or a storage container for liquid, solid and / or gaseous substances can be provided within the housing of a process module, so that chemical reactions are self-sufficient and independent of an external one Supply can take place.
  • the process modules can, for example, functionalities for heating, cooling, mixing, separating, pressure control, ventilation and / or have venting, which make it possible to carry out a chemical reaction and to regulate reaction conditions.
  • a fill level is detected in this process module in order to detect the amount of material present in at least one of the process modules and to be processed by this process module.
  • a pressure is recorded in this process module in order to record the amount of material present in at least one of the process modules and to be processed by this process module.
  • This can be provided as an alternative or to obtain redundant information in addition to the last-mentioned embodiment.
  • This embodiment also represents a simple possibility for detecting the amount of material present in a process module to be processed by the process module via suitable pressure sensors. In each process module it is also possible to record the amount of material present in the process module to be processed by this process module by means of a detection of the pressure in the process module.
  • Individual process modules can be switched between the pull principle and the push principle, or vice versa. Alternatively, it is possible for individual process modules integrated in a corresponding production system to change over automatically and automatically. This can also make it necessary to redesign the other controls of a process module, such as controlling internal buffer networks of a process module.
  • Each electronic device of a process module can be connected to the communication network mentioned above in terms of communication technology.
  • the electronic device preferably detects when the respective process module is connected to the communication network, whereupon the electronic device automatically feeds an identification signal into the communication network from which, for example, the type of the process module emerges.
  • Each electronic device can be set up to control and / or regulate the respective process module for independently carrying out a specific process section of the production.
  • independent means that the process section is carried out by means of the process module, without the need to control and / or regulate the process section or a part thereof from a device apart from the process module.
  • the process module can then work independently.
  • the electronic devices can be set up in such a way that process modules connected to the communication network in terms of communication technology can automatically communicate with one another, for example in such a way that at least one process module automatically queries information from at least one further process module.
  • This automatic communication of the process modules with one another is possible in particular if process modules which are connected to the communication network output an identification signal into the communication network by means of their respective electronic device, which signal is received by process modules already connected to the communication network.
  • the receiving process modules can hereby be informed of the address of the new process module connected to the communication network.
  • Process modules connected to the communication network or their electronic devices can be a trigger that these process modules also emit a corresponding identification signal into the communication network, which in turn is received by the process module newly connected to the communication network.
  • the production plant can have plug and play functionality.
  • the information that can be queried by the further process modules can include information in the form of given and / or expected process parameters relating to the process section that is to be performed or to be performed by the process module that provides this information. These process parameters can then be used to control and / or regulate a querying process module.
  • This is particularly advantageous for a subsequent process module, which is provided for the further processing of an intermediate product produced by a previous process module in a temporally preceding process section.
  • it is of considerable importance which properties the intermediate product produced by the previous process module has in order to be able to determine which boundary conditions exist for the production of the desired end product from the intermediate product or must be complied with by the subsequent process module.
  • At least one process module has at least one fill level sensor that detects the material fill level in this process module and is connected in terms of communication technology to the electronic device of this process module, the electronic device being set up from the material fill level respectively detected in the process module from the material fill level detected in each case in the process module. to determine the amount of material to be processed by the process module.
  • At least one process module has at least one pressure sensor that detects the pressure in this process module and is connected to the electronic device of this process module in terms of communication technology, the electronic device being set up from the pressure detected by the pressure sensor in each case in the process module to determine the amount of material to be processed by the process module.
  • a further advantageous embodiment provides that each has an outflow for an upstream process module and at the same time an inflow for an upstream process module
  • Process module forming line is arranged at least one electrically controllable, communication technology connected to the electronic device of the upstream process module or the downstream process module. In this way, a material flow or a material supply from or into a process module can be regulated in a simple manner.
  • FIG. 1 is an embodiment of a production plant 1 according to the invention for the production of a chemical and / or pharmaceutical product.
  • the material flow is indicated by arrow 7.
  • the production system 1 comprises n process modules 2 which are connected to one another in terms of production technology and are autonomous in terms of control technology.
  • Each process module 2 has an electronic device 3, in particular a control and / or regulating device, which is set up to continuously or discretely record a quantity of material that is present in the respective process module 2 and is to be processed by this process module 2 and to assign it with a predetermined quantity limit value to compare.
  • Each electronic device 3 is also set up to actuate an inflow of the respective process module 2 to increase a mass inflow into this process module 2 if the amount of material present in this process module 2 to be processed by this process module 2 is less than the quantity limit value, the At the same time, there is a flow of a further process module 2 which is immediately upstream of this process module 2 in terms of production technology.
  • the production system 1 and its process modules 3 thus work according to the pull principle.
  • each has an outlet for an upstream process module 2 and at the same time an inlet for a line 4 forming a downstream process module 2, an electrically controllable valve which is connected to the electronic device 3 of the downstream process module 2 in terms of communication technology 5 arranged.
  • Each process module 2 further comprises a communication level with the electronic device 3 of this process module 2 that detects the material fill level in this process module 2 connected level sensor 6, wherein the electronic device 3 is set up to determine from the material level detected by the level sensor 6 in each case the amount of material present in the process module 2 to be processed by the process module 2.
  • each process module 2 can have a pressure sensor, not shown, which detects the pressure in this process module 2 and is connected in terms of communication technology to the electronic device 3 of this process module 2, the electronic device 3 being set up to use the pressure detected by the pressure sensor in each case in the process module 2 to determine the amount of material to be processed by the process module 2.
  • each electronic device 3 can have a microprocessor and a suitable storage medium.
  • FIG. 2 shows a schematic representation of a further exemplary embodiment for a production plant 1 according to the invention.
  • This production plant 1 differs from that in FIG Figure 1 Embodiment shown in particular in that each electronic device 3 is set up to actuate a sequence of the respective process module 2 to increase a mass flow from this process module 2 if the amount of material present in this process module 2 to be processed by this process module 2 is greater than the quantity limit value is, the process is at the same time an inflow of a further process module 2 which is immediately downstream in terms of production technology.

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Automation & Control Theory (AREA)
  • General Factory Administration (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Description

Die Arbeiten, die zu dieser Erfindung geführt haben, wurden gemäß der Finanzhilfevereinbarung Nr. 228867 im Zuge des Siebten Rahmenprogramms der Europäischen Union RP7/2007-2013 gefördert.The work leading to this invention was carried out in accordance with grant agreement no. 228867 funded under the European Union's Seventh Framework Program FP7 / 2007-2013.

Die Erfindung betrifft ein Verfahren zum Betreiben einer produktionstechnisch miteinander verbundene, regelungstechnisch autarke Prozessmodule aufweisenden Produktionsanlage für die Produktion eines chemischen und/oder pharmazeutischen Produktes.The invention relates to a method for operating a production system which is connected to one another in terms of production technology and has control technology-independent process modules for the production of a chemical and / or pharmaceutical product.

Des Weiteren betrifft die Erfindung eine Produktionsanlage für die Produktion eines chemischen und/oder pharmazeutischen Produktes.Furthermore, the invention relates to a production plant for the production of a chemical and / or pharmaceutical product.

Für die Herstellung eines bestimmten chemischen und/oder pharmazeutischen Produktes ist es erforderlich, eine Produktionsanlage mit individuell gestalteter Anlagenstruktur bereitzustellen, um die jeweilig verfahrenstechnisch erforderlichen Prozessschritte in einzelnen Prozessabschnitten durchführen zu können. Ist die Herstellung dieses bestimmten Produktes nicht mehr gewünscht, wird die Produktionsanlage üblicherweise wieder abgebaut, um an derselben Stelle eine andere Produktionsanlage mit individuell gestalteter Anlagenstruktur aufbauen zu können, mit der ein anderes chemisches und/oder pharmazeutisches Produkt hergestellt werden kann. Dieses Auf- und Abbauen von Produktionsanlagen ist sehr zeit- und kostenaufwändig. Es besteht daher ein ständiges Bedürfnis, den mit der Produktion verschiedener chemischer und/oder pharmazeutischer Produkte verbundenen Aufwand zu verringern.For the production of a certain chemical and / or pharmaceutical product, it is necessary to provide a production plant with an individually designed plant structure in order to be able to carry out the respective process steps required in individual process sections. If the production of this particular product is no longer desired, the production plant is usually dismantled again in order to be able to build another production plant with an individually designed plant structure in the same place, with which another chemical and / or pharmaceutical product can be produced. This assembly and dismantling of production plants is very time-consuming and costly. There is therefore a constant need to reduce the effort associated with the production of various chemical and / or pharmaceutical products.

Das Dokument EP 1 932 828 A2 beschreibt ein Verfahren zum Betreiben von einem Prozessmodul innerhalb einer Produktionsanlage sowie die entsprechende Produktionsanlage. Der Massenzulauf in das Prozessmodul beziehungsweise Massenablauf aus dem Prozessmodul wird erhöht oder erniedrigt, wenn die in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge kleiner oder größer als einer Mengengrenzwert ist. Das Dokument US 4 332 590 A beschreibt ein ganz ähnliches Verfahren zum Betreiben von einem Prozessmodul innerhalb einer Produktionsanlage sowie auch hier die entsprechende Produktionsanlage.The document EP 1 932 828 A2 describes a method for operating a process module within a production plant and the corresponding production plant. The mass flow into the process module or mass flow from the process module is increased or decreased if the amount of material present in this process module to be processed by this process module is less than or greater than a quantity limit. The document US 4,332,590 A describes a very similar process for operating a process module within a production plant as well as the corresponding production plant.

Zur Umgehung dieser Problematik kann eine Produktionsanlage modular aus einzelnen prozesstechnisch miteinander verbindbaren, regelungstechnisch autarken Prozessmodulen aufgebaut werden. Solche Produktionsanlagen erfordern jedoch neuartige Regelungskonzepte, da bei herkömmlichen Produktionsanlagen eingesetzte Regelungskonzepte nicht ohne Weiteres auf modular aus regelungstechnisch autarken Prozessmodulen aufgebaute Produktionsanlagen übertragbar sind.To circumvent this problem, a production plant can be built up modularly from individual process modules that can be connected to one another in terms of process technology and are autonomous in terms of control technology. However, such production plants require new types of control concepts, since control concepts used in conventional production plants are not readily transferable to production plants which are modularly constructed from process technology-independent process modules.

Aufgabe der Erfindung ist es, ein Regelungskonzept für eine produktionstechnisch miteinander verbundene, regelungstechnisch autarke Prozessmodule aufweisende Produktionsanlage für die Produktion eines chemischen und/oder pharmazeutischen Produktes bereitzustellen.It is the object of the invention to provide a control concept for a production plant for production of a chemical and / or pharmaceutical product that is connected to one another in terms of production technology and has control technology autonomous process modules.

Diese Aufgabe wird durch ein Verfahren mit den Merkmalen gemäß Patentanspruch 1 und eine Produktionsanlage mit den Merkmalen gemäß Patentanspruch 6 gelöst. Bevorzugte Ausgestaltungen der Erfindung sind in den Unteransprüchen angegeben, die jeweils für sich genommen oder in beliebiger Kombination miteinander einen Aspekt der Erfindung darstellen können.This object is achieved by a method with the features according to claim 1 and a production plant with the features according to claim 6. Preferred refinements of the invention are specified in the subclaims, which in each case can be taken on their own or in any combination with one another, an aspect of the invention.

Mit Patentanspruch 1 wird ein Verfahren zum Betreiben einer produktionstechnisch miteinander verbundene, regelungstechnisch autarke Prozessmodule aufweisenden Produktionsanlage für die Produktion eines chemischen und/oder pharmazeutischen Produktes vorgeschlagen, wobei für jedes Prozessmodul kontinuierlich oder diskret eine jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge erfasst und mit einem vorgegebenen Mengengrenzwert verglichen wird, wobei

  • ein Massenzulauf in das jeweilige Prozessmodul erhöht oder erniedrigt wird, wenn die jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge kleiner oder größer als der Mengengrenzwert ist, wobei der Massenzulauf gleichzeitig ein Massenablauf eines produktionstechnisch diesem Prozessmodul unmittelbar vorgeschalteten weiteren Prozessmoduls ist, oder
  • ein Massenablauf aus dem jeweiligen Prozessmodul erhöht oder erniedrigt wird, wenn die jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge größer oder kleiner als der Mengengrenzwert ist, wobei der Massenablauf gleichzeitig ein Massenzulauf eines produktionstechnisch diesem Prozessmodul unmittelbar nachgeschalteten weiteren Prozessmoduls ist. Im Rahmen der Erfindung können die Begriffe "Mengengrenzwert" und "Mengensollwert" als gleichbedeutend verwendet werden.
Patent claim 1 proposes a method for operating a production system that is connected to one another in terms of production technology and that has control technology-independent process modules for the production of a chemical and / or pharmaceutical product, wherein for each process module a respective quantity of material present in this process module that is to be processed by this process module is continuously or discretely is recorded and compared with a predetermined quantity limit, whereby
  • a mass inflow into the respective process module is increased or decreased if the amount of material present in this process module to be processed by this process module is smaller or greater than the quantity limit, the mass inflow being at the same time a mass flow of a further process module connected directly upstream of this process module, or
  • a mass flow from the respective process module is increased or decreased if the amount of material present in this process module to be processed by this process module is greater or less than the quantity limit value, the mass flow being at the same time a mass inflow of a further process module directly downstream of this process module in terms of production technology. In the context of the invention, the terms “quantity limit value” and “quantity setpoint value” can be used as synonymous.

Wird ein Massenzulauf in das jeweilige Prozessmodul erhöht, wenn die jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge kleiner als der Mengengrenzwert ist, wobei der Massenzulauf gleichzeitig ein Massenablauf eines produktionstechnisch diesem Prozessmodul unmittelbar vorgeschalteten weiteren Prozessmoduls ist, arbeitet die Produktionsanlage bzw. deren Prozessmodule nach einem aus der Fertigungstechnik bekannten Regelungskonzept, dem sogenannten Pull-Prinzip. Wird hingegen ein Massenablauf aus dem jeweiligen Prozessmodul erhöht, wenn die jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge größer als der Mengengrenzwert ist, wobei der Massenablauf gleichzeitig ein Massenzulauf eines produktionstechnisch diesem Prozessmodul unmittelbar nachgeschalteten weiteren Prozessmoduls ist, arbeitet die Produktionsanlage bzw. deren Prozessmodule nach einem ebenfalls aus der Fertigungstechnik bekannten Regelungskonzept, dem sogenannten Push-Prinzip. Beim Pull-Prinzip geht folglich der Impuls zur Aktivität von einem jeweilig einem Prozessmodul nachgeschalteten Prozessmodul aus, wohingegen beim Push-Prinzip der Impuls der Aktivität von einem jeweilig einem Prozessmodul vorgeschalteten Prozessmodul ausgeht. Wesentlich ist für die Erfindung, dass alle Prozessmodule einer Produktionsanlage einheitlich nach dem Pull-Prinzip oder dem Push-Prinzip arbeiten. Würden nicht alle Prozessmodule einer Produktionsanlage einheitlich nach dem Pull-Prinzip oder dem Push-Prinzip arbeiten, würden diese Prozessmodule gegeneinander arbeiten. Auch ist es nicht sinnvoll, einen Ablauf eines vorgeschalteten Prozessmoduls unabhängig von einem Zulauf eines dem vorgeschalteten Prozessmodul nachgeschalteten Prozessmoduls zu regeln.If a mass inflow into the respective process module is increased when the quantity of material to be processed by this process module that is present in this process module is smaller than the quantity limit value, the mass inflow being at the same time a mass outflow of a further process module connected directly upstream of this process module, the production system or their process modules according to a control concept known from manufacturing technology, the so-called pull principle. If, on the other hand, a mass flow from the respective process module is increased, if the amount of material to be processed by this process module that is present in this process module is greater than the quantity limit, whereby the mass flow is at the same time a mass inflow of a further process module immediately downstream in production technology, the production system or Their process modules according to a control concept, also known from manufacturing technology, the so-called push principle. In the pull principle, the impulse for the activity therefore originates from a process module which is respectively connected downstream of a process module, whereas with the push principle the impulse of activity originates from a process module which is respectively connected upstream of a process module. It is essential for the invention that all process modules of a production plant work uniformly according to the pull principle or the push principle. If not all process modules of a production plant work uniformly according to the pull principle or the push principle, these process modules would work against each other. It also doesn't make sense to run an upstream one Process module to be controlled independently of an inflow of a process module downstream of the upstream process module.

Die produktionstechnisch miteinander verbindbaren, regelungstechnisch autarken Prozessmodule können als als Ganzes transportierbare Einheiten ausgebildet sein, welche zu einem gewünschten Produktionsort, an dem eine entsprechend ausgestattete, modular aufgebaute Produktionsanlage aufgestellt werden soll, transportierbar bzw. von diesem Ort nach Abschluss der gewünschten Produktion weg transportierbar sind. Dies ermöglicht eine einfache und produktionskostenreduzierende Wiederverwendung einzelner Prozessmodule an verschiedenen Produktionsorten. Hierzu kann ein Prozessmodul ein einen einfachen Transport des Prozessmoduls ermöglichendes Gehäuse aufweisen, in dem zur Durchführung des gewünschten Prozessabschnitts wenigstens ein Prozessaggregat angeordnet und dessen Dimensionierung standardisiert sein kann.The process modules, which can be connected to one another in terms of production technology and are autonomous in terms of control technology, can be designed as transportable units as a whole, which can be transported to a desired production location at which a suitably equipped, modularly constructed production system is to be set up, or can be transported away from this location after completion of the desired production . This enables simple and production cost-reducing reuse of individual process modules at different production locations. For this purpose, a process module can have a housing that enables easy transportation of the process module, in which at least one process unit can be arranged and the dimensions of which can be standardized in order to carry out the desired process section.

An einem Produktionsort können die Prozessmodule, vorzugsweise über standardisierte Kupplungen, an ein fest installiertes Kommunikationsnetz und an ein Versorgungsnetz angeschlossen werden, mit dem die Prozessmodule mit Stoff und/oder Energie versorgt und/oder in das Stoffe abgegeben werden können, so dass mittels der Prozessmodule im Wesentlichen autark wenigstens eine chemische Batch-Reaktion und/oder eine kontinuierliche Produktion durchgeführt werden kann. Über das Versorgungsnetz können insbesondere feste, flüssig und/oder gasförmige Stoffe oder Stoffgemische transportiert werden, die einphasig oder mehrphasig, beispielsweise als Suspension oder Emulsion, vorliegen können. Beispielsweise kann das Versorgungsnetz eine Druckluftleitung zur Zufuhr von Druckluft, eine Speisewasserleitung zur Zufuhr von Wasser, eine Elektroleitung zur Zufuhr von elektrischer Energie, eine Stoffleitung zur Zufuhr von Edukten und/oder Hilfsstoffen und/oder zur Abfuhr von Produkten, Nebenprodukten und/oder Abfallstoffen, eine Kühlleitung zur Zufuhr von Kälte beziehungsweise zur Abfuhr von Wärme und/oder eine Heizleitung zur Zufuhr von Wärme beziehungsweise zur Abfuhr von Kälte aufweisen. Als Kommunikationsnetz kommen verschiedene kabelgebundene oder kabellose Kommunikationsnetze in Betracht. Über das Kommunikationsnetz kann ein standardisierter Informationsaustausch der an das Kommunikationsnetz angeschlossenen Prozessmodule untereinander erfolgen.At a production site, the process modules, preferably via standardized couplings, can be connected to a permanently installed communication network and to a supply network with which the process modules can be supplied with substance and / or energy and / or released into the substance, so that by means of the process modules essentially self-sufficient at least one chemical batch reaction and / or continuous production can be carried out. In particular, solid, liquid and / or gaseous substances or mixtures of substances which can be single-phase or multi-phase, for example as a suspension or emulsion, can be transported via the supply network. For example, the supply network can include a compressed air line for the supply of compressed air, a feed water line for the supply of water, an electric line for the supply of electrical energy, a material line for the supply of starting materials and / or auxiliary materials and / or for the removal of products, by-products and / or waste materials, have a cooling line for supplying cold or for removing heat and / or a heating line for supplying heat or for removing cold. Various wired or wireless communication networks can be considered as the communication network. A standardized exchange of information between the process modules connected to the communication network can take place via the communication network.

Zusätzlich oder alternativ können innerhalb des Gehäuses eines Prozessmoduls ein an das Versorgungsnetz anschließbarer Speicher für Stoff und/oder Energie, und/oder ein Vorratsbehälter für flüssige, feste und/oder gasförmige Stoffe, vorgesehen sein, so dass chemische Reaktionen autark und unabhängig von einer externen Versorgung erfolgen können. Die Prozessmodule können beispielsweise Funktionalitäten zum Heizen, Kühlen, Vermischen, Trennen, Druckregeln, Belüften und/oder Entlüften aufweisen, die es ermöglichen eine chemische Reaktion durchzuführen und Reaktionsbedingungen zu regeln.Additionally or alternatively, a storage for substance and / or energy and / or a storage container for liquid, solid and / or gaseous substances can be provided within the housing of a process module, so that chemical reactions are self-sufficient and independent of an external one Supply can take place. The process modules can, for example, functionalities for heating, cooling, mixing, separating, pressure control, ventilation and / or have venting, which make it possible to carry out a chemical reaction and to regulate reaction conditions.

Gemäß einer vorteilhaften Ausgestaltung wird zur Erfassung der jeweilig in wenigstens einem der Prozessmodule vorhandenen, von diesem Prozessmodul zu verarbeitenden Materialmenge ein Füllstand in diesem Prozessmodul erfasst. Dies stellt eine einfache Möglichkeit zur Erfassung der jeweilig in einem Prozessmodul vorhandenen, von dem Prozessmodul zu verarbeitenden Materialmenge über geeignete Füllstandssensoren dar. Es kann auch in jedem Prozessmodul eine Erfassung der in dem Prozessmodule vorhandenen, von diesem Prozessmodul zu verarbeitenden Materialmenge über eine Erfassung des Füllstands in dem Prozessmodul erfolgen.According to an advantageous embodiment, a fill level is detected in this process module in order to detect the amount of material present in at least one of the process modules and to be processed by this process module. This represents a simple way of detecting the amount of material present in a process module to be processed by the process module via suitable fill level sensors. It is also possible in each process module to record the amount of material present in the process module to be processed by this process module by detecting the fill level done in the process module.

Nach einer weiteren vorteilhaften Ausgestaltung wird zur Erfassung der jeweilig in wenigstens einem der Prozessmodule vorhandenen, von diesem Prozessmodul zu verarbeitenden Materialmenge ein Druck in diesem Prozessmodul erfasst. Dies kann alternativ oder zum Erhalt redundanter Informationen zusätzlich zu der zuletzt genannten Ausgestaltung vorgesehen sein. Auch diese Ausgestaltung stellt eine einfache Möglichkeit zur Erfassung der jeweilig in einem Prozessmodul vorhandenen, von dem Prozessmodul zu verarbeitenden Materialmenge über geeignete Drucksensoren dar. Es kann auch in jedem Prozessmodul eine Erfassung der in dem Prozessmodule vorhandenen, von diesem Prozessmodul zu verarbeitenden Materialmenge über eine Erfassung des Drucks in dem Prozessmodul erfolgen.According to a further advantageous embodiment, a pressure is recorded in this process module in order to record the amount of material present in at least one of the process modules and to be processed by this process module. This can be provided as an alternative or to obtain redundant information in addition to the last-mentioned embodiment. This embodiment also represents a simple possibility for detecting the amount of material present in a process module to be processed by the process module via suitable pressure sensors. In each process module it is also possible to record the amount of material present in the process module to be processed by this process module by means of a detection of the pressure in the process module.

Mit Patentanspruch 6 wird eine Produktionsanlage für die Produktion eines chemischen und/oder pharmazeutischen Produktes vorgeschlagen, aufweisend wenigstens zwei produktionstechnisch miteinander verbindbare, regelungstechnisch autarke Prozessmodule, wobei jedes Prozessmodul eine eigene elektronische Einrichtung, insbesondere Steuer- und/oder Regeleinrichtung, aufweist, die eingerichtet ist, kontinuierlich oder diskret eine jeweilig in dem jeweiligen Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge zu erfassen und mit einem vorgegebenen Mengengrenzwert zu vergleichen, wobei jede elektronische Einrichtung des Weiteren eingerichtet ist,

  • einen Zulauf des jeweiligen Prozessmoduls zur Erhöhung oder Erniedrigung eines Massenzulaufs in dieses Prozessmodul zu betätigen, wenn die jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge kleiner oder größer als der Mengengrenzwert ist, wobei der Zulauf gleichzeitig ein Ablauf eines produktionstechnisch diesem Prozessmodul unmittelbar vorgeschalteten weiteren Prozessmoduls ist, oder
  • einen Ablauf des jeweiligen Prozessmoduls zur Erhöhung oder Erniedrigung eines Massenablaufs aus diesem Prozessmodul zu betätigen, wenn die jeweilig in diesem Prozessmodul vorhandene, von diesem Prozessmodul zu verarbeitende Materialmenge größer oder kleiner als der Mengengrenzwert ist, wobei der Ablauf gleichzeitig ein Zulauf eines produktionstechnisch diesem Prozessmodul unmittelbar nachgeschalteten weiteren Prozessmoduls ist.
Patent claim 6 proposes a production system for the production of a chemical and / or pharmaceutical product, comprising at least two process modules that can be connected to one another in terms of production technology and are autonomous in terms of control technology, each process module having its own electronic device, in particular a control and / or regulating device, which is set up to continuously or discretely record and compare a respective amount of material that is to be processed in the respective process module by this process module, and to compare it with a predetermined amount limit, each electronic device being furthermore set up,
  • to actuate an inflow of the respective process module to increase or decrease a mass inflow into this process module if the amount of material present in this process module to be processed by this process module is smaller or larger than the quantity limit value, the inflow simultaneously being a production process of this process module directly upstream further process module, or
  • to actuate a sequence of the respective process module to increase or decrease a mass flow from this process module, if the respective in this process module Existing quantity of material to be processed by this process module is greater or smaller than the quantity limit value, the process being at the same time an inflow of a further process module immediately downstream in terms of production technology.

Mit dieser Produktionsanlage sind die oben mit Bezug auf das Verfahren genannten Vorteile und Ausführungsformen entsprechend verbunden.The advantages and embodiments mentioned above with regard to the method are correspondingly connected to this production plant.

Einzelne Prozessmodule können zwischen von dem Pull-Prinzip auf das Push-Prinzip, oder umgekehrt, umgestellt werden. Alternativ ist es möglich, dass sich einzelne in eine entsprechende Produktionsanlage integrierte Prozessmodule automatisch und selbsttätig umstellen. Dies kann zusätzlich eine Neuauslegung der sonstigen Regelung eines Prozessmoduls erforderlich machen, wie beispielsweise der Regelung interner Puffernetzwerke eines Prozessmoduls.Individual process modules can be switched between the pull principle and the push principle, or vice versa. Alternatively, it is possible for individual process modules integrated in a corresponding production system to change over automatically and automatically. This can also make it necessary to redesign the other controls of a process module, such as controlling internal buffer networks of a process module.

Jede elektronische Einrichtung eines Prozessmoduls kann kommunikationstechnisch mit dem oben genannten Kommunikationsnetz verbindbar sein. Vorzugsweise erfasst die elektronische Einrichtung, wenn eine Verbindung des jeweiligen Prozessmoduls mit dem Kommunikationsnetz erfolgt, woraufhin von der elektronischen Einrichtung automatisch ein Identifikationssignal in das Kommunikationsnetz eingespeist wird, aus dem beispielsweise die Gattung des Prozessmoduls hervorgeht.Each electronic device of a process module can be connected to the communication network mentioned above in terms of communication technology. The electronic device preferably detects when the respective process module is connected to the communication network, whereupon the electronic device automatically feeds an identification signal into the communication network from which, for example, the type of the process module emerges.

Jede elektronische Einrichtung kann eingerichtet sein, das jeweilige Prozessmodul zur eigenständigen Durchführung eines bestimmten Prozessabschnitts der Produktion zu steuern und/oder zu regeln. Eigenständig bedeutet hierbei, dass der Prozessabschnitt mittels des Prozessmoduls durchgeführt wird, ohne dass hierzu eine Steuerung und/oder Regelung des Prozessabschnitts oder eines Teils davon von einer Einrichtung abseits des Prozessmoduls erfolgen muss. Das Prozessmodul kann hiernach also autark arbeiten.Each electronic device can be set up to control and / or regulate the respective process module for independently carrying out a specific process section of the production. In this context, independent means that the process section is carried out by means of the process module, without the need to control and / or regulate the process section or a part thereof from a device apart from the process module. The process module can then work independently.

Die elektronischen Einrichtungen können des Weiteren derart eingerichtet sein, dass kommunikationstechnisch mit dem Kommunikationsnetz verbundene Prozessmodule automatisch miteinander kommunizieren können, beispielsweise derart, dass wenigstens ein Prozessmodul automatisch Informationen von zumindest einem weiteren Prozessmodul abfragt. Diese automatische Kommunikation der Prozessmodule untereinander ist insbesondere möglich, wenn Prozessmodule, die an das Kommunikationsnetz angeschlossen werden, mittels ihrer jeweiligen elektronischen Einrichtung ein Identifikationssignal in das Kommunikationsnetz ausgeben, welches von bereits mit dem Kommunikationsnetz verbundenen Prozessmodulen empfangen wird. Den empfangenden Prozessmodulen kann hierdurch die Adresse des neu an das Kommunikationsnetz angeschlossenen Prozessmoduls mitgeteilt werden. Dies kann beispielsweise bei den bereits mit dem Kommunikationsnetz verbundenen Prozessmodulen bzw. deren elektronischen Einrichtungen ein Auslöser sein, dass auch diese Prozessmodule ein entsprechendes Identifikationssignal in das Kommunikationsnetz abgeben, welches wiederum von dem neu an das Kommunikationsnetz angeschlossenen Prozessmodul empfangen wird. Die Produktionsanlage kann diesbezüglich eine Plug and Play-Funktionalität aufweisen.Furthermore, the electronic devices can be set up in such a way that process modules connected to the communication network in terms of communication technology can automatically communicate with one another, for example in such a way that at least one process module automatically queries information from at least one further process module. This automatic communication of the process modules with one another is possible in particular if process modules which are connected to the communication network output an identification signal into the communication network by means of their respective electronic device, which signal is received by process modules already connected to the communication network. The receiving process modules can hereby be informed of the address of the new process module connected to the communication network. This can be the case, for example, with the Process modules connected to the communication network or their electronic devices can be a trigger that these process modules also emit a corresponding identification signal into the communication network, which in turn is received by the process module newly connected to the communication network. In this regard, the production plant can have plug and play functionality.

Die von den weiteren Prozessmodulen abfragbaren Informationen können Informationen in Form von gegebenen und/oder zu erwartenden Prozessparametern bezüglich des von dem diese Informationen zur Verfügung stellenden Prozessmodul durchgeführten bzw. durchzuführenden Prozessabschnitts umfassen. Diese Prozessparameter können dann zur Steuerung und/oder Regelung eines abfragenden Prozessmoduls verwendet werden. Insbesondere ist dies für ein nachfolgendes Prozessmodul vorteilhaft, welches zur Weiterverarbeitung eines von einem vorhergehenden Prozessmodul in einem zeitlich vorhergehenden Prozessabschnitt hergestellten Zwischenproduktes vorgesehen ist. Für diese Weiterverarbeitung durch das nachfolgende Prozessmodul ist es von erheblicher Bedeutung, welche Eigenschaften das von dem vorhergehenden Prozessmodul hergestellte Zwischenprodukt aufweist, um ermitteln zu können, welche Randbedingungen zur Herstellung des gewünschten Endproduktes aus dem Zwischenprodukt vorliegen bzw. von dem nachfolgenden Prozessmodul eingehalten werden müssen.The information that can be queried by the further process modules can include information in the form of given and / or expected process parameters relating to the process section that is to be performed or to be performed by the process module that provides this information. These process parameters can then be used to control and / or regulate a querying process module. This is particularly advantageous for a subsequent process module, which is provided for the further processing of an intermediate product produced by a previous process module in a temporally preceding process section. For this further processing by the subsequent process module, it is of considerable importance which properties the intermediate product produced by the previous process module has in order to be able to determine which boundary conditions exist for the production of the desired end product from the intermediate product or must be complied with by the subsequent process module.

Gemäß einer vorteilhaften Ausgestaltung weist wenigstens ein Prozessmodul zumindest einen den Materialfüllstand in diesem Prozessmodul erfassenden, kommunikationstechnisch mit der elektronischen Einrichtung dieses Prozessmoduls verbundenen Füllstandssensor auf, wobei die elektronische Einrichtung eingerichtet ist, aus dem jeweilig über den Füllstandssensor erfassten Materialfüllstand die jeweilig in dem Prozessmodul vorhandene, von dem Prozessmodul zu verarbeitenden Materialmenge zu ermitteln. Hiermit sind die oben mit Bezug auf die entsprechende Ausgestaltung des Verfahrens genannten Vorteile und Ausführungsformen entsprechend verbunden.According to an advantageous embodiment, at least one process module has at least one fill level sensor that detects the material fill level in this process module and is connected in terms of communication technology to the electronic device of this process module, the electronic device being set up from the material fill level respectively detected in the process module from the material fill level detected in each case in the process module. to determine the amount of material to be processed by the process module. The advantages and embodiments mentioned above with reference to the corresponding embodiment of the method are correspondingly connected to this.

Nach einer weiteren vorteilhaften Ausgestaltung weist wenigstens ein Prozessmodul zumindest einen den Druck in diesem Prozessmodul erfassenden, kommunikationstechnisch mit der elektronischen Einrichtung dieses Prozessmoduls verbundenen Drucksensor auf, wobei die elektronische Einrichtung eingerichtet ist, aus dem jeweilig über den Drucksensor erfassten Druck die jeweilig in dem Prozessmodul vorhandene, von dem Prozessmodul zu verarbeitenden Materialmenge zu ermitteln. Auch hiermit sind die oben mit Bezug auf die entsprechende Ausgestaltung des Verfahrens genannten Vorteile und Ausführungsformen entsprechend verbunden.According to a further advantageous embodiment, at least one process module has at least one pressure sensor that detects the pressure in this process module and is connected to the electronic device of this process module in terms of communication technology, the electronic device being set up from the pressure detected by the pressure sensor in each case in the process module to determine the amount of material to be processed by the process module. The advantages and embodiments mentioned above with reference to the corresponding embodiment of the method are also connected accordingly.

Eine weitere vorteilhafte Ausgestaltung sieht vor, dass an jeder einen Ablauf für ein vorgeschaltetes Prozessmodul und gleichzeitig einen Zulauf für ein diesem Prozessmodul nachgeschaltetes Prozessmodul bildenden Leitung wenigstens ein elektrisch ansteuerbares, kommunikationstechnisch mit der elektronischen Einrichtung des vorgeschalteten Prozessmoduls oder des nachgeschalteten Prozessmoduls verbundenes Ventil angeordnet ist. Hierdurch kann ein Materialablauf bzw. ein Materialzulauf aus bzw. in ein Prozessmodul auf einfache Art und Weise geregelt werden.A further advantageous embodiment provides that each has an outflow for an upstream process module and at the same time an inflow for an upstream process module Process module forming line is arranged at least one electrically controllable, communication technology connected to the electronic device of the upstream process module or the downstream process module. In this way, a material flow or a material supply from or into a process module can be regulated in a simple manner.

Nachfolgend wird die Erfindung unter Bezugnahme auf die anliegenden Figuren anhand von bevorzugten Ausführungsbeispielen exemplarisch erläutert, wobei die nachfolgend dargestellten Merkmale sowohl jeweils für sich genommen als auch in Kombination miteinander einen Aspekt der Erfindung darstellen können. Es zeigen

  • Figur 1:eine schematische Darstellung eines Ausführungsbeispiels für eine erfindungsgemäße Produktionsanlage und
  • Figur 2:eine schematische Darstellung eines weiteren Ausführungsbeispiels für eine erfindungsgemäße Produktionsanlage.
In the following, the invention is explained by way of example with reference to the attached figures on the basis of preferred exemplary embodiments, the features illustrated below being able to represent an aspect of the invention both individually and in combination with one another. Show it
  • Figure 1 : a schematic representation of an embodiment for a production plant according to the invention and
  • Figure 2 : A schematic representation of a further embodiment for a production plant according to the invention.

In Figur 1 ist ein Ausführungsbeispiel für eine erfindungsgemäße Produktionsanlage 1 für die Produktion eines chemischen und/oder pharmazeutischen Produktes. Der Materialfluss ist durch den Pfeil 7 angedeutet. Die Produktionsanlage 1 umfasst n produktionstechnisch miteinander verbundene, regelungstechnisch autarke Prozessmodule 2 auf. Jedes Prozessmodul 2 weist eine elektronische Einrichtung 3, insbesondere Steuer- und/oder Regeleinrichtung, auf, die eingerichtet ist, kontinuierlich oder diskret eine jeweilig in dem jeweiligen Prozessmodul 2 vorhandene, von diesem Prozessmodul 2 zu verarbeitende Materialmenge zu erfassen und mit einem vorgegebenen Mengengrenzwert zu vergleichen. Jede elektronische Einrichtung 3 ist des Weiteren eingerichtet, einen Zulauf des jeweiligen Prozessmoduls 2 zur Erhöhung eines Massenzulaufs in dieses Prozessmodul 2 zu betätigen, wenn die jeweilig in diesem Prozessmodul 2 vorhandene, von diesem Prozessmodul 2 zu verarbeitende Materialmenge kleiner als der Mengengrenzwert ist, wobei der Zulauf gleichzeitig ein Ablauf eines produktionstechnisch diesem Prozessmodul 2 unmittelbar vorgeschalteten weiteren Prozessmoduls 2 ist. Die Produktionsanlage 1 bzw. deren Prozessmodule 3 arbeiten somit nach dem Pull-Prinzip. Um den jeweiligen Zulauf entsprechend erhöhen zu können, ist an jeder einen Ablauf für ein vorgeschaltetes Prozessmodul 2 und gleichzeitig einen Zulauf für ein diesem Prozessmodul 2 nachgeschaltetes Prozessmodul 2 bildenden Leitung 4 ein elektrisch ansteuerbares, kommunikationstechnisch mit der elektronischen Einrichtung 3 des nachgeschalteten Prozessmoduls 2 verbundenes Ventil 5 angeordnet.In Figure 1 is an embodiment of a production plant 1 according to the invention for the production of a chemical and / or pharmaceutical product. The material flow is indicated by arrow 7. The production system 1 comprises n process modules 2 which are connected to one another in terms of production technology and are autonomous in terms of control technology. Each process module 2 has an electronic device 3, in particular a control and / or regulating device, which is set up to continuously or discretely record a quantity of material that is present in the respective process module 2 and is to be processed by this process module 2 and to assign it with a predetermined quantity limit value to compare. Each electronic device 3 is also set up to actuate an inflow of the respective process module 2 to increase a mass inflow into this process module 2 if the amount of material present in this process module 2 to be processed by this process module 2 is less than the quantity limit value, the At the same time, there is a flow of a further process module 2 which is immediately upstream of this process module 2 in terms of production technology. The production system 1 and its process modules 3 thus work according to the pull principle. In order to be able to correspondingly increase the respective inflow, each has an outlet for an upstream process module 2 and at the same time an inlet for a line 4 forming a downstream process module 2, an electrically controllable valve which is connected to the electronic device 3 of the downstream process module 2 in terms of communication technology 5 arranged.

Jedes Prozessmodul 2 umfasst des Weiteren einen den Materialfüllstand in diesem Prozessmodul 2 erfassenden, kommunikationstechnisch mit der elektronischen Einrichtung 3 dieses Prozessmoduls 2 verbundenen Füllstandssensor 6, wobei die elektronische Einrichtung 3 eingerichtet ist, aus dem jeweilig über den Füllstandssensor 6 erfassten Materialfüllstand die jeweilig in dem Prozessmodul 2 vorhandene, von dem Prozessmodul 2 zu verarbeitenden Materialmenge zu ermitteln. Alternativ oder zusätzlich kann jedes Prozessmodul 2 einen den Druck in diesem Prozessmodul 2 erfassenden, kommunikationstechnisch mit der elektronischen Einrichtung 3 dieses Prozessmoduls 2 verbundenen, nicht dargestellten Drucksensor aufweisen, wobei die elektronische Einrichtung 3 eingerichtet ist, aus dem jeweilig über den Drucksensor erfassten Druck die jeweilig in dem Prozessmodul 2 vorhandene, von dem Prozessmodul 2 zu verarbeitenden Materialmenge zu ermitteln. Hierzu kann jede elektronische Einrichtung 3 einen Mikroprozessor und ein geeignetes Speichermedium aufweisen.Each process module 2 further comprises a communication level with the electronic device 3 of this process module 2 that detects the material fill level in this process module 2 connected level sensor 6, wherein the electronic device 3 is set up to determine from the material level detected by the level sensor 6 in each case the amount of material present in the process module 2 to be processed by the process module 2. Alternatively or additionally, each process module 2 can have a pressure sensor, not shown, which detects the pressure in this process module 2 and is connected in terms of communication technology to the electronic device 3 of this process module 2, the electronic device 3 being set up to use the pressure detected by the pressure sensor in each case in the process module 2 to determine the amount of material to be processed by the process module 2. For this purpose, each electronic device 3 can have a microprocessor and a suitable storage medium.

Figur 2 zeigt eine schematische Darstellung eines weiteren Ausführungsbeispiels für eine erfindungsgemäße Produktionsanlage 1. Diese Produktionsanlage 1 unterscheidet sich von dem in Figur 1 gezeigten Ausführungsbeispiel insbesondere dadurch, dass jede elektronische Einrichtung 3 eingerichtet ist, einen Ablauf des jeweiligen Prozessmoduls 2 zur Erhöhung eines Massenablaufs aus diesem Prozessmodul 2 zu betätigen, wenn die jeweilig in diesem Prozessmodul 2 vorhandene, von diesem Prozessmodul 2 zu verarbeitende Materialmenge größer als der Mengengrenzwert ist, wobei der Ablauf gleichzeitig ein Zulauf eines produktionstechnisch diesem Prozessmodul 2 unmittelbar nachgeschalteten weiteren Prozessmoduls 2 ist. An jeder einen Ablauf für ein vorgeschaltetes Prozessmodul 2 und gleichzeitig einen Zulauf für ein diesem Prozessmodul 2 nachgeschaltetes Prozessmodul 2 bildenden Leitung 4 ist ein elektrisch ansteuerbares, kommunikationstechnisch mit der elektronischen Einrichtung 3 des vorgeschalteten Prozessmoduls 2 verbundenes Ventil 5 angeordnet. Figure 2 shows a schematic representation of a further exemplary embodiment for a production plant 1 according to the invention. This production plant 1 differs from that in FIG Figure 1 Embodiment shown in particular in that each electronic device 3 is set up to actuate a sequence of the respective process module 2 to increase a mass flow from this process module 2 if the amount of material present in this process module 2 to be processed by this process module 2 is greater than the quantity limit value is, the process is at the same time an inflow of a further process module 2 which is immediately downstream in terms of production technology. An electrically controllable valve 5, which is connected to the electronic device 3 of the upstream process module 2 in terms of communication technology, is arranged on each of an outlet for an upstream process module 2 and at the same time an inlet for a line 4 forming a downstream process module 2.

Claims (9)

  1. Method for operating a production plant (1) for producing a chemical and/or pharmaceutical product, having process modules (2) which are connected to one another for production purposes and are autonomous for regulating purposes, wherein for each process module (2) an amount of material that is respectively present in this process module (2) and is to be processed by this process module (2) is continuously or discretely detected and compared with a prescribed limit value for the amount, wherein
    - a mass inflow into the respective process module (2) is increased if the amount of material that is respectively present in this process module (2) and is to be processed by this process module (2) is less than the limit value for the amount, the mass inflow at the same time being a mass outflow of a further process module (2) connected directly upstream of this process module (2) for production purposes, with the result that all process modules (2) of the production plant (1) consistently operate according to the pull principle, or
    - a mass outflow from the respective process module (2) is increased if the amount of material that is respectively present in this process module (2) and is to be processed by this process module (2) is greater than the limit value for the amount, the mass outflow at the same time being a mass inflow of a further process module (2) connected directly downstream of this process module (2) for production purposes, with the result that all process modules (2) of the production plant (1) consistently operate according to the push principle.
  2. Method according to Claim 1, characterized in that the process modules (2) which can be connected to one another for production purposes and are autonomous for regulating purposes are in the form of units which can be transported as a whole and can be transported to a desired production location, at which an accordingly equipped production plant (1) of modular construction is intended to be erected, and can be transported away from this location after the desired production has been concluded.
  3. Method according to Claim 2, characterized in that the process modules (2) at the production location can be connected, preferably using standardized couplings, to a permanently installed communication network and to a supply network, with which the process modules (2) can be supplied with material and/or energy and/or into which materials can be discharged, with the result that at least a chemical batch reaction and/or continuous production can be carried out in a substantially autonomous manner by means of the process modules (2).
  4. Method according to one of the preceding claims, characterized in that, for detecting the amount of material that is respectively present in at least one of the process modules (2) and is to be processed by this process module (2), a filling level in this process module (2) is detected.
  5. Method according to one of the preceding claims, characterized in that, for detecting the amount of material that is respectively present in at least one of the process modules (2) and is to be processed by this process module (2), a pressure in this process module (2) is detected.
  6. Production plant (1) for producing a chemical and/or pharmaceutical product, having at least two process modules (2) which can be connected to one another for production purposes and are autonomous for regulating purposes, wherein each process module (2) has an electronic device (3), in particular a control and/or regulating device, which is set up to detect continuously or discretely an amount of material that is respectively present in the respective process module (2) and is to be processed by this process module (2) and compare it with a prescribed limit value for the amount, wherein each electronic device (3) is also set up
    - to actuate an inflow of the respective process module (2) to increase a mass inflow into this process module (2) if the amount of material that is respectively present in this process module (2) and is to be processed by this process module (2) is less than the limit value for the amount, the inflow at the same time being an outflow of a further process module (2) connected directly upstream of this process module (2) for production purposes, with the result that all process modules (2) of the production plant (1) consistently operate according to the pull principle, or
    - to actuate an outflow of the respective process module (2) to increase a mass outflow from this process module (2) if the amount of material that is respectively present in this process module (2) and is to be processed by this process module (2) is greater than the limit value for the amount, the outflow at the same time being an inflow of a further process module (2) connected directly downstream of this process module (2) for production purposes, with the result that all process modules (2) of the production plant (1) consistently operate according to the push principle.
  7. Production plant (1) according to Claim 6, characterized in that at least one process module (2) has at least one filling level sensor (6) detecting the filling level of the material in this process module (2) and connected for communication purposes to the electronic device (3) of this process module (2), the electronic device (3) being set up to determine, from the filling level of material respectively detected by means of the filling level sensor (6), the amount of material that is respectively present in the process module (2) and is to be processed by the process module (2).
  8. Production plant (1) according to Claim 6 or 7, characterized in that at least one process module (2) has at least one pressure sensor detecting the pressure in this process module (2) and connected for communication purposes to the electronic device (3) of this process module (2), the electronic device (3) being set up to determine, from the pressure respectively detected by means of the pressure sensor, the amount of material that is respectively present in the process module (2) and is to be processed by the process module (2).
  9. Production plant (1) according to one of Claims 6 to 8, characterized in that on each line (4) forming an outflow for an upstream process module (2) and at the same time an inflow for a process module (2) connected downstream of this process module (2) there is arranged at least one electrically activatable valve (6) connected for communication purposes to the electronic device (3) of the upstream process module (2) or of the downstream process module (2).
EP14821573.4A 2013-12-20 2014-12-16 Method for operating a production plant of modular design Active EP3083032B1 (en)

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PCT/EP2014/077953 WO2015091474A1 (en) 2013-12-20 2014-12-16 Method for operating a production plant of modular design

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DE102017117876A1 (en) * 2017-08-07 2019-02-07 Festo Ag & Co. Kg Production module for a production plant
CN119677585A (en) * 2022-06-13 2025-03-21 贝伦治疗公益公司 Modular manufacture of pharmaceuticals

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BR112016014433A2 (en) 2017-08-08
PL3083032T3 (en) 2021-01-25
SG11201604858TA (en) 2016-07-28
CN105813726A (en) 2016-07-27
ES2825100T3 (en) 2021-05-14
CN111604017A (en) 2020-09-01
SG10201805179WA (en) 2018-07-30
US10369541B2 (en) 2019-08-06
KR102361819B1 (en) 2022-02-10
CA2934403A1 (en) 2015-06-25
JP2020171924A (en) 2020-10-22
KR20160098450A (en) 2016-08-18
CA2934403C (en) 2022-07-19
DE102013114720A1 (en) 2015-06-25
WO2015091474A1 (en) 2015-06-25
JP2017510866A (en) 2017-04-13
BR112016014433B1 (en) 2021-09-08
JP7013527B2 (en) 2022-01-31
US20160325260A1 (en) 2016-11-10
DK3083032T3 (en) 2020-10-26
EP3083032A1 (en) 2016-10-26

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