EP2766087A4 - NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS - Google Patents

NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS

Info

Publication number: EP2766087A4
Authority: EP; European Patent Office
Prior art keywords: reasons; treatment; neurological disorders; electric stimulation; regular electric
Prior art date: 2011-10-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP12839657.9A

Other languages

German (de)

French (fr)

Other versions

EP2766087A2 (en

Inventor

Warren M Grill

David T Brocker

Merill J Birdno

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Duke University

Original Assignee

Duke University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-11

Filing date

2012-10-11

Publication date

2015-05-06

2012-10-11 Application filed by Duke University filed Critical Duke University

2012-10-11 Priority to EP18167953.1A priority Critical patent/EP3372274B1/en

2012-10-11 Priority to EP20175204.5A priority patent/EP3718596B1/en

2014-08-20 Publication of EP2766087A2 publication Critical patent/EP2766087A2/en

2015-05-06 Publication of EP2766087A4 publication Critical patent/EP2766087A4/en

Status Ceased legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/36167—Timing, e.g. stimulation onset
- A61N1/36178—Burst or pulse train parameters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0534—Electrodes for deep brain stimulation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36189—Control systems using modulation techniques
- A61N1/36196—Frequency modulation

Landscapes

Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Developmental Disabilities (AREA)
Child & Adolescent Psychology (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Electrotherapy Devices (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP12839657.9A 2011-10-11 2012-10-11 NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS Ceased EP2766087A4 (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
EP18167953.1A EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP20175204.5A EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161545791P	2011-10-11	2011-10-11
US201161558871P	2011-11-11	2011-11-11
PCT/US2012/059787 WO2013055940A2 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
EP20175204.5A Division EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Division EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Publications (2)

Publication Number	Publication Date
EP2766087A2 EP2766087A2 (en)	2014-08-20
EP2766087A4 true EP2766087A4 (en)	2015-05-06

Family

ID=48082746

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
EP12839657.9A Ceased EP2766087A4 (en)	2011-10-11	2012-10-11	NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
EP20175204.5A Active EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Active EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
EP20175204.5A Active EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Active EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Country Status (5)

Country	Link
EP (3)	EP2766087A4 (en)
CN (2)	CN106955417B (en)
AU (4)	AU2012322739A1 (en)
CA (2)	CA3169207A1 (en)
WO (1)	WO2013055940A2 (en)

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US11013924B2 (en)	2008-10-03	2021-05-25	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
US9802046B2 (en)	2008-10-03	2017-10-31	Duke University	Non-regular electrical stimulation patterns for improved efficiency in treating Parkinson's Disease
US8798755B2 (en)	2008-10-03	2014-08-05	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
US8923981B2 (en)	2008-10-03	2014-12-30	Duke University	Non-regular electrical stimulation patterns designed with a cost function for treating neurological disorders
AU2009300264B2 (en)	2008-10-03	2014-07-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
AU2011258026A1 (en)	2010-05-27	2012-12-20	Ndi Medical, Llc	Waveform shapes for treating neurological disorders optimized for energy efficiency
US9821159B2 (en)	2010-11-16	2017-11-21	The Board Of Trustees Of The Leland Stanford Junior University	Stimulation devices and methods
AU2011328900B2 (en)	2010-11-16	2015-03-19	The Board Of Trustees Of The Leland Stanford Junior University	Systems and methods for treatment of dry eye
EP2945691B1 (en)	2013-01-21	2019-03-06	Cala Health, Inc.	Devices for controlling tremor
EP2967817B1 (en)	2013-03-12	2021-03-10	Oculeve, Inc.	Implant delivery devices and systems
US8996137B2 (en)	2013-04-19	2015-03-31	Oculeve, Inc.	Nasal stimulation devices and methods
CA2916241C (en) *	2013-05-22	2023-07-04	Deep Brain Innovations LLC	Deep brain stimulator and method of use
CN111569263B (en)	2013-12-23	2024-04-26	脑深部创新有限责任公司	Programming system for deep brain stimulator system
CA2940533A1 (en)	2014-02-25	2015-09-03	Oculeve, Inc.	Polymer formulations for nasolacrimal stimulation
WO2015187712A1 (en)	2014-06-02	2015-12-10	Cala Health, Inc.	Systems and methods for peripheral nerve stimulation to treat tremor
US9687652B2 (en)	2014-07-25	2017-06-27	Oculeve, Inc.	Stimulation patterns for treating dry eye
WO2016065213A1 (en)	2014-10-22	2016-04-28	Oculeve, Inc.	Implantable nasal stimulator systems and methods
AU2015335776B2 (en)	2014-10-22	2020-09-03	Oculeve, Inc.	Stimulation devices and methods for treating dry eye
WO2016065211A1 (en)	2014-10-22	2016-04-28	Oculeve, Inc.	Contact lens for increasing tear production
DE102014117429A1 (en) *	2014-11-27	2016-06-02	Forschungszentrum Jülich GmbH	Apparatus and method for effective invasive neurostimulation by means of varying stimulus sequences
AU2016261228B2 (en) *	2015-05-08	2020-05-07	Duke University	Systems and methods for spinal cord stimulation
CN112915380B (en)	2015-06-10	2025-01-21	卡拉健康公司	Systems and methods for peripheral nerve stimulation to treat tremor using a detachable treatment and monitoring unit
AU2016297965B2 (en)	2015-07-30	2019-04-04	Boston Scientific Neuromodulation Corporation	User interface for custom patterned electrical stimulation
EP3352843B1 (en) *	2015-09-23	2021-06-23	Cala Health, Inc.	Device for peripheral nerve stimulation in the finger to treat hand tremors
WO2017066187A1 (en) *	2015-10-15	2017-04-20	Boston Scientific Neuromodulation Corporation	User interface for neurostimulation waveform composition
US10426958B2 (en)	2015-12-04	2019-10-01	Oculeve, Inc.	Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US10391313B2 (en)	2015-12-04	2019-08-27	Boston Scientific Neuromodulation Corporation	Systems and methods for the development of therapy paradigms for neurological treatments
CA3011993C (en)	2016-01-21	2024-05-14	Cala Health, Inc.	Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10252048B2 (en)	2016-02-19	2019-04-09	Oculeve, Inc.	Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
AU2017260237A1 (en)	2016-05-02	2018-11-22	Oculeve, Inc.	Intranasal stimulation for treatment of meibomian gland disease and blepharitis
US12233265B2 (en)	2016-08-25	2025-02-25	Cala Health, Inc.	Systems and methods for treating cardiac dysfunction through peripheral nerve stimulation
WO2018102535A1 (en)	2016-12-02	2018-06-07	Oculeve, Inc.	Apparatus and method for dry eye forecast and treatment recommendation
US11331480B2 (en)	2017-04-03	2022-05-17	Cala Health, Inc.	Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
EP3740274A4 (en)	2018-01-17	2021-10-27	Cala Health, Inc.	Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11890468B1 (en)	2019-10-03	2024-02-06	Cala Health, Inc.	Neurostimulation systems with event pattern detection and classification
WO2021146557A1 (en) *	2020-01-15	2021-07-22	Carnegie Mellon University	Neuromodulation using electrical stimulation

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US3833005A (en) *	1971-07-26	1974-09-03	Medtronic Inc	Compared count digitally controlled pacemaker
US5018524A (en) *	1985-05-15	1991-05-28	Hansen Gu	Apparatus and method for generating vital information signals
US5095904A (en) *	1989-09-08	1992-03-17	Cochlear Pty. Ltd.	Multi-peak speech procession
US20100152807A1 (en) *	2008-10-03	2010-06-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders

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CN1003839B (en) *	1986-04-24	1989-04-12	顾涵森	Apparatus and method for generating vital information signal
US6366813B1 (en) *	1998-08-05	2002-04-02	Dilorenzo Daniel J.	Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US7010351B2 (en) *	2000-07-13	2006-03-07	Northstar Neuroscience, Inc.	Methods and apparatus for effectuating a lasting change in a neural-function of a patient
DE10318071A1 (en) *	2003-04-17	2004-11-25	Forschungszentrum Jülich GmbH	Device for desynchronizing neuronal brain activity
JP2009508558A (en) *	2005-09-15	2009-03-05	コーニンクレッカフィリップスエレクトロニクスエヌヴィ	Apparatus and method for electrical stimulation / sensing in vivo

2012
- 2012-10-11 CA CA3169207A patent/CA3169207A1/en active Pending
- 2012-10-11 CN CN201710058910.9A patent/CN106955417B/en active Active
- 2012-10-11 AU AU2012322739A patent/AU2012322739A1/en not_active Abandoned
- 2012-10-11 CA CA2846639A patent/CA2846639C/en active Active
- 2012-10-11 EP EP12839657.9A patent/EP2766087A4/en not_active Ceased
- 2012-10-11 EP EP20175204.5A patent/EP3718596B1/en active Active
- 2012-10-11 WO PCT/US2012/059787 patent/WO2013055940A2/en active Application Filing
- 2012-10-11 CN CN201280049892.3A patent/CN103889503B/en active Active
- 2012-10-11 EP EP18167953.1A patent/EP3372274B1/en active Active
2017
- 2017-05-08 AU AU2017203037A patent/AU2017203037B2/en active Active
2019
- 2019-07-15 AU AU2019205970A patent/AU2019205970B2/en active Active
2021
- 2021-05-04 AU AU2021202778A patent/AU2021202778A1/en not_active Abandoned

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833005A (en) *	1971-07-26	1974-09-03	Medtronic Inc	Compared count digitally controlled pacemaker
US5018524A (en) *	1985-05-15	1991-05-28	Hansen Gu	Apparatus and method for generating vital information signals
US5095904A (en) *	1989-09-08	1992-03-17	Cochlear Pty. Ltd.	Multi-peak speech procession
US20100152807A1 (en) *	2008-10-03	2010-06-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders

Also Published As

Publication number	Publication date
EP3718596A1 (en)	2020-10-07
AU2019205970B2 (en)	2021-02-04
CA2846639A1 (en)	2013-04-18
WO2013055940A3 (en)	2014-05-30
EP2766087A2 (en)	2014-08-20
CA2846639C (en)	2022-10-18
CN103889503A (en)	2014-06-25
CN106955417A (en)	2017-07-18
AU2017203037A1 (en)	2017-06-01
CN106955417B (en)	2021-08-20
CN103889503B (en)	2017-03-08
EP3718596B1 (en)	2023-06-28
WO2013055940A2 (en)	2013-04-18
AU2017203037B2 (en)	2019-04-18
AU2021202778A1 (en)	2021-05-27
AU2019205970A1 (en)	2019-08-01
CA3169207A1 (en)	2013-04-18
AU2012322739A1 (en)	2014-03-13
EP3372274A1 (en)	2018-09-12
EP3372274B1 (en)	2020-06-24

Publication	Publication Date	Title
EP2766087A4 (en)	2015-05-06	NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
EP2340078A4 (en)	2013-09-04	ELECTRICALLY NON-REGULAR STIMULATION CONFIGURATIONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
GB2492487B (en)	2015-09-16	Cannabinoids for use in the treatment of neurodegenerative diseases or disorders
EP2879760A4 (en)	2016-03-30	Devices and methods for magnetic stimulation for the treatment of neurological disorders
HK1201728A1 (en)	2015-09-11	Factor xii inhibitors for the treatment of neurological inflammatory disorders xii
EP2877184A4 (en)	2016-03-30	COMPOSITIONS AND TREATMENT FOR DISEASES AND OCULAR DISORDERS
EP2874692A4 (en)	2016-04-06	NON-REGULAR ELECTRICAL STIMULATION REASONS FOR GREATER TREATMENT EFFICIENCY OF PARKINSON'S DISEASE
BR112014013843A2 (en)	2017-07-04	use of devices for the treatment of neurological diseases
RS56595B1 (en)	2018-02-28	Estrogenic derivatives for use in the treatment of neurological disorders
EP2773342A4 (en)	2015-08-26	COMPOSITIONS USEFUL FOR THE TREATMENT OF VIRAL DISEASES
EP2846825A4 (en)	2016-03-16	TREATMENT OF INFLAMMATORY DISORDERS IN NON-HUMAN MAMMALS
EP3025716A4 (en)	2016-10-19	SUBSTANCE FOR THE TREATMENT OR RELIEF OF PAIN
EP2623494A4 (en)	2014-04-02	AGENT FOR THE TREATMENT OF OCULAR DISEASES
EP2782566A4 (en)	2016-01-13	L-SERINE COMPOSITIONS, METHODS AND USES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES AND DISORDERS
EP2906594A4 (en)	2016-03-30	METHODS AND COMPOSITIONS FOR THE TREATMENT OF MULTIPLE SCLEROSIS AND RELATED DISORDERS
IL235058A0 (en)	2014-12-31	Pharmaceutical combinations for the treatment of metabolic disorders
HK1204573A1 (en)	2015-11-27	Treatment of inflammatory skin disorders
EP2922534A4 (en)	2016-05-11	METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
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SMT201600395B (en)	2017-01-10	PANTOTENATE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
EP2825173A4 (en)	2015-12-09	CALMODULIN INHIBITORS FOR THE TREATMENT OF RIBOSOMIC DISORDERS AND RIBOSOMAPATHIES
EP2673363A4 (en)	2015-04-15	TREATMENT OF ANGIOGENESIS DISORDERS
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EP2536436A4 (en)	2015-01-14	ANTIMIR-451 FOR THE TREATMENT OF POLYCYTHEMICS
ZA201309554B (en)	2014-08-27	Compounds and pharmaceutical combinations for the treatment of neurodegenerative and ischemic brain diseases

Legal Events

Date	Code	Title	Description
2014-07-18	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2014-08-20	17P	Request for examination filed	Effective date: 20140327
2014-08-20	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2015-05-06	A4	Supplementary search report drawn up and despatched	Effective date: 20150407
2015-05-06	DAX	Request for extension of the european patent (deleted)
2015-05-06	RIC1	Information provided on ipc code assigned before grant	Ipc: A61N 1/00 20060101AFI20150330BHEP Ipc: A61N 1/36 20060101ALI20150330BHEP Ipc: A61N 1/05 20060101ALI20150330BHEP
2016-03-16	17Q	First examination report despatched	Effective date: 20160215
2018-02-26	REG	Reference to a national code	Ref country code: DE Ref legal event code: R003
2018-06-01	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2018-07-04	18R	Application refused	Effective date: 20180226