EP2540742A4 - Anti-cyr61 protein monoclonal antibodies and uses thereof - Google Patents
Anti-cyr61 protein monoclonal antibodies and uses thereofInfo
- Publication number
- EP2540742A4 EP2540742A4 EP10834216.3A EP10834216A EP2540742A4 EP 2540742 A4 EP2540742 A4 EP 2540742A4 EP 10834216 A EP10834216 A EP 10834216A EP 2540742 A4 EP2540742 A4 EP 2540742A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- monoclonal antibodies
- protein monoclonal
- cyr61 protein
- cyr61
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Pain & Pain Management (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200910199937A CN101709088A (en) | 2009-12-04 | 2009-12-04 | Monoclonal antibody for resisting Cyr61 protein and application thereof |
CN200910199938A CN101709089A (en) | 2009-12-04 | 2009-12-04 | Monoclonal antibody for resisting Cyr61 protein and application thereof |
PCT/CN2010/079208 WO2011066783A1 (en) | 2009-12-04 | 2010-11-27 | Anti-cyr61 protein monoclonal antibodies and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2540742A1 EP2540742A1 (en) | 2013-01-02 |
EP2540742A4 true EP2540742A4 (en) | 2014-02-12 |
Family
ID=44114613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10834216.3A Withdrawn EP2540742A4 (en) | 2009-12-04 | 2010-11-27 | Anti-cyr61 protein monoclonal antibodies and uses thereof |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2540742A4 (en) |
WO (1) | WO2011066783A1 (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1263852C (en) * | 1996-03-15 | 2006-07-12 | 穆尼恩公司 | Extracellular matrix signalling molecules |
AU2001271365A1 (en) * | 2000-06-21 | 2002-01-02 | Wyeth | Cyr61 as a target for treatment and diagnosis of breast cancer |
EP1322778A4 (en) * | 2000-09-29 | 2005-06-15 | Wyeth Corp | Use of cyr61 in the treatment and diagnosis of human uterine leiomyomas |
CN101709089A (en) * | 2009-12-04 | 2010-05-19 | 上海市免疫学研究所 | Monoclonal antibody for resisting Cyr61 protein and application thereof |
CN101709088A (en) * | 2009-12-04 | 2010-05-19 | 上海市免疫学研究所 | Monoclonal antibody for resisting Cyr61 protein and application thereof |
-
2010
- 2010-11-27 EP EP10834216.3A patent/EP2540742A4/en not_active Withdrawn
- 2010-11-27 WO PCT/CN2010/079208 patent/WO2011066783A1/en active Application Filing
Non-Patent Citations (5)
Title |
---|
ANONYMOUS: "Cyr61 (N-16): sc-8560", XP002718211, Retrieved from the Internet <URL:http://datasheets.scbt.com/sc-8560.pdf> [retrieved on 20131219] * |
ANONYMOUS: "Human Cyr61/CCN1 Antibody Monoclonal Mouse IgG1 Clone # 365108 Catalog Number: MAB4055", 6 May 2010 (2010-05-06), XP055094502, Retrieved from the Internet <URL:http://www.rndsystems.com/pdf/MAB4055.pdf> [retrieved on 20131219] * |
ANONYMOUS: "new products: R&D Systems New Products March 2007", 1 March 2007 (2007-03-01), XP055094501, Retrieved from the Internet <URL:http://www.woongbee.com/0NewHome/RnD/Literature/NewPro/200703_5886.pdf> [retrieved on 20131219] * |
See also references of WO2011066783A1 * |
ZHANG QIUYU ET AL: "A Critical Role of Cyr61 in Interleukin-17-Dependent Proliferation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis", ARTHRITIS & RHEUMATISM, JOHN WILEY & SONS, INC, US, vol. 60, no. 12, 1 December 2009 (2009-12-01), pages 3602 - 3612, XP009148188, ISSN: 0004-3591, [retrieved on 20091130], DOI: 10.1002/ART.24999 * |
Also Published As
Publication number | Publication date |
---|---|
EP2540742A1 (en) | 2013-01-02 |
WO2011066783A1 (en) | 2011-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP20181616T1 (en) | Fully human anti-vap-1 monoclonal antibodies | |
HK1176940A1 (en) | Monoclonal antibodies and diagnostic uses thereof | |
PT2510011E (en) | Monoclonal antibodies that bind b7h6 and uses thereof | |
IL215649A (en) | Anti-tnf-α monoclonal antibodies and uses thereof | |
IL232008A (en) | Isolated alpha-4beta-7 heterodimer specific antigen binding protein and various aspects related thereto | |
IL200610A0 (en) | Human monoclonal anti-ip-10 antibodies and uses thereof | |
EP2494062A4 (en) | Anti-glp-1r antibodies and their uses | |
EP2525813A4 (en) | Anti-ilt5 antibodies and ilt5-binding antibody fragments | |
IL216115A0 (en) | Humanized anti-egfl7 antibodies and methods using same | |
HK1168871A1 (en) | Monoclonal antibodies | |
IL215291A0 (en) | NOVEL ANTI-a5BETA1 ANTIBODIES AND USES THEREOF | |
IL220536A0 (en) | Anti - bv8 antibodies and uses thereof | |
EP2475383A4 (en) | Humanized antibodies specific for hsp65-derived peptide-6 methods and uses thereof | |
IL214527A0 (en) | Anti-mst1r antibodies and uses thereof | |
HK1158977A1 (en) | Anti-ferroportin monoclonal antibodies and uses thereof | |
EP2484694A4 (en) | Monoclonal antibody against human hig-1 polypeptide | |
EP2540742A4 (en) | Anti-cyr61 protein monoclonal antibodies and uses thereof | |
IL218438A0 (en) | Humanized antibodies specific for hsp65-derived peptide-6 methods and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20120704 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/577 20060101ALI20131220BHEP Ipc: A61P 19/04 20060101ALI20131220BHEP Ipc: C07K 16/18 20060101AFI20131220BHEP Ipc: A61P 29/00 20060101ALI20131220BHEP Ipc: A61K 39/395 20060101ALI20131220BHEP Ipc: A61P 35/00 20060101ALI20131220BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20140114 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20140812 |