EP2473506A4 - Compounds and compositions for treating cancer - Google Patents
Compounds and compositions for treating cancerInfo
- Publication number
- EP2473506A4 EP2473506A4 EP10814469A EP10814469A EP2473506A4 EP 2473506 A4 EP2473506 A4 EP 2473506A4 EP 10814469 A EP10814469 A EP 10814469A EP 10814469 A EP10814469 A EP 10814469A EP 2473506 A4 EP2473506 A4 EP 2473506A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- compounds
- treating cancer
- cancer
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27575409P | 2009-09-02 | 2009-09-02 | |
PCT/US2010/047615 WO2011028860A2 (en) | 2009-09-02 | 2010-09-02 | Compounds and compositions for treating cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2473506A2 EP2473506A2 (en) | 2012-07-11 |
EP2473506A4 true EP2473506A4 (en) | 2013-03-06 |
Family
ID=43625764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10814469A Withdrawn EP2473506A4 (en) | 2009-09-02 | 2010-09-02 | Compounds and compositions for treating cancer |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2473506A4 (en) |
JP (1) | JP2013503888A (en) |
KR (1) | KR20120104165A (en) |
CN (1) | CN102625805A (en) |
AU (1) | AU2010289493A1 (en) |
BR (1) | BR112012004701A2 (en) |
CA (1) | CA2772614A1 (en) |
IN (1) | IN2012DN01878A (en) |
WO (1) | WO2011028860A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101629642B1 (en) | 2014-06-25 | 2016-06-13 | 서울대학교산학협력단 | Food composition, pharmaceutical composition, animal medicine and feed composition against fatty liver with piperlongumine |
GB201715008D0 (en) * | 2017-09-18 | 2017-11-01 | Inst De Medicina Molecular Faculdade De Medicina Univ De Lisboa | TRPV2 Antagonists |
KR20200081633A (en) | 2018-12-27 | 2020-07-08 | 주식회사 티에스디라이프사이언스 | A pharmaceutical composition for treatment or prevention of biliary atresia comprising piperlongumine |
CN110002987B (en) * | 2019-03-22 | 2020-09-15 | 南通大学 | Phenylallylidene cyclohexenone derivative, preparation method and use |
CN117229205A (en) * | 2023-09-14 | 2023-12-15 | 中国医学科学院基础医学研究所 | Preparation method and pharmaceutical application of phenyl acrylamide RHbDD1 inhibitor |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102146054A (en) * | 2010-02-10 | 2011-08-10 | 新昌县来益科技开发有限公司 | Piperlongumine derivatives and medicinal composition and application to preparation of medicament for inhibiting tumor growth thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101951768A (en) * | 2007-02-14 | 2011-01-19 | 玛尔斯有限公司 | The neurogenicity compound |
EP2135078B1 (en) * | 2007-03-09 | 2013-08-21 | DiscoveRx Corporation | Methods for identifying agents and their use for the prevention or stabilization of fibrosis |
-
2010
- 2010-09-02 CN CN2010800418987A patent/CN102625805A/en active Pending
- 2010-09-02 JP JP2012528029A patent/JP2013503888A/en active Pending
- 2010-09-02 IN IN1878DEN2012 patent/IN2012DN01878A/en unknown
- 2010-09-02 BR BR112012004701A patent/BR112012004701A2/en not_active IP Right Cessation
- 2010-09-02 CA CA2772614A patent/CA2772614A1/en not_active Abandoned
- 2010-09-02 AU AU2010289493A patent/AU2010289493A1/en not_active Abandoned
- 2010-09-02 EP EP10814469A patent/EP2473506A4/en not_active Withdrawn
- 2010-09-02 WO PCT/US2010/047615 patent/WO2011028860A2/en active Application Filing
- 2010-09-02 KR KR1020127007113A patent/KR20120104165A/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102146054A (en) * | 2010-02-10 | 2011-08-10 | 新昌县来益科技开发有限公司 | Piperlongumine derivatives and medicinal composition and application to preparation of medicament for inhibiting tumor growth thereof |
Non-Patent Citations (2)
Title |
---|
HUANG: "A facile and highly stereoselective synthesis of (2E)-, (2E,4E)-unsaturated amides and related natural products", TETRAHEDRON LETTERS, vol. 28, no. 19, 1 January 1987 (1987-01-01), pages 2159 - 2162, XP055050870, DOI: 10.1016/S0040-4039(00)96069-6 * |
See also references of WO2011028860A2 * |
Also Published As
Publication number | Publication date |
---|---|
AU2010289493A1 (en) | 2012-04-19 |
BR112012004701A2 (en) | 2018-06-12 |
JP2013503888A (en) | 2013-02-04 |
KR20120104165A (en) | 2012-09-20 |
IN2012DN01878A (en) | 2015-08-21 |
WO2011028860A3 (en) | 2011-07-21 |
EP2473506A2 (en) | 2012-07-11 |
WO2011028860A2 (en) | 2011-03-10 |
CN102625805A (en) | 2012-08-01 |
CA2772614A1 (en) | 2011-03-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20120302 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MASSACHUSETTS GENERAL HOSPITAL Owner name: CANTHERA THERAPEUTICS, INC. |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20130201 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/5377 20060101ALI20130128BHEP Ipc: C07D 211/86 20060101AFI20130128BHEP Ipc: A61K 31/4412 20060101ALI20130128BHEP Ipc: A61P 35/00 20060101ALI20130128BHEP |
|
17Q | First examination report despatched |
Effective date: 20131029 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20140509 |