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EP2453408B1 - Verarbeitungsverfahren von Röntgenbildern zur Erkennung einer Stenose - Google Patents

Verarbeitungsverfahren von Röntgenbildern zur Erkennung einer Stenose Download PDF

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Publication number
EP2453408B1
EP2453408B1 EP10306249.3A EP10306249A EP2453408B1 EP 2453408 B1 EP2453408 B1 EP 2453408B1 EP 10306249 A EP10306249 A EP 10306249A EP 2453408 B1 EP2453408 B1 EP 2453408B1
Authority
EP
European Patent Office
Prior art keywords
artery
interest
image
images
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP10306249.3A
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English (en)
French (fr)
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EP2453408A1 (de
Inventor
Régis VAILLANT
Sébastien Gorges
Vincent Bismuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Electric Co
Original Assignee
General Electric Co
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Filing date
Publication date
Application filed by General Electric Co filed Critical General Electric Co
Priority to EP10306249.3A priority Critical patent/EP2453408B1/de
Priority to US13/290,450 priority patent/US8880148B2/en
Priority to CN201110387801.4A priority patent/CN102592274B/zh
Publication of EP2453408A1 publication Critical patent/EP2453408A1/de
Application granted granted Critical
Publication of EP2453408B1 publication Critical patent/EP2453408B1/de
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    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20068—Projection on vertical or horizontal image axis
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30101—Blood vessel; Artery; Vein; Vascular

Definitions

  • the invention relates to the field of medical imaging and more particularly that of radiology and finds application in the field of interventional radiological vascular imaging.
  • Vascular interventional radiology includes procedures performed under the control of imaging and in particular to treat myocardial ischemia.
  • Myocardial ischemia is a disease that affects more than a third of people in developed countries results in a stenosis that is to say a narrowing of an artery.
  • a cardiologist practitioner uses the interventional imaging that allows the characterization of possible lesions and the quantification of coronary arteries and more particularly stenoses to properly choose the size of the stent to introduce.
  • the cardiologist practitioner uses an image of the zone comprising an artery to be treated on which, manually, he positions several markers along the artery to be treated to perform a stenosis analysis, that is to say to determine the where the stenosis is located and determine the size of the stent needed to treat the stenosis.
  • This detection and this quantification require an interaction of the radiologist practitioner with a medical imaging device and a preliminary step of detecting the artery to be treated.
  • the invention overcomes these disadvantages.
  • the invention relates to a method for processing radiological images of a region of interest of a patient, the radiological images being 2D projection images, in which an elongated tool has been previously inserted into a artery, the method comprising the following step: obtaining at least one set of images consisting of a first image and a second image of the region of interest, the first image being an image of the region of interest in which a contrast product has been previously injected, the second image being an image of the region of interest without product or with a minimal amount of contrast medium, each set corresponding to a given angulation; the method comprising, for each set, the following steps: segmenting the first image to detect a plurality of arteries of the region of interest; segmenting the second image to detect and isolate the tool; defining in the first segmented image a plurality of lines, each line defining an artery; determining, from the second segmented image and the defined lines, an artery of interest corresponding to the artery in which the tool has been inserted
  • the invention relates to a medical imaging system comprising means for implementing the method according to the first aspect of the invention.
  • the invention relates to a computer program comprising machine instructions for carrying out a method according to the first aspect of the invention.
  • the figure 1 schematically illustrates a medical imaging system 100 for the acquisition of radiological images.
  • the medical imaging system 100 comprises a support 1 intended to receive a patient 10 to examine a source 2 intended to emit an X-ray beam 3, a detector 4 placed in front of the source 2 and configured to detect the X-rays emitted by the source 2, a control unit 6, a storage unit 7 and a display unit 8.
  • the X-ray source 2 and the detector 4 are connected by a C-shaped arm 5.
  • Such an arm 5 is more commonly called a bow.
  • the arm 5 can be oriented in three degrees of freedom.
  • the detector 4 may be a solid state image sensor comprising, for example, cesium iodide phosphor (scintillator) on an amorphous silicon transistor / photodiode array.
  • Other suitable detectors are: a CCD sensor, direct digital detector that directly converts X-rays into digital signals.
  • the detector 4 illustrated on the figure 1 is flat and defines a flat image surface, other geometries can of course be suitable.
  • the control unit 6 is connected to the hoop 5 by wired or wireless connection.
  • the control unit 6 makes it possible to control the acquisition by fixing several parameters such as the dose of radiation to be emitted by the X-ray source and the angular positioning of the arm 5.
  • the control unit 6 makes it possible to control the position of the arm 5, that is to say the position of the source 2 with respect to the detector 4.
  • the control unit 6 may comprise a reading device (not shown) for example a floppy disk drive a CD-ROM drive, DVD-ROM, or connection ports for reading the instructions of the method of processing a medium instructions (not shown), such as a floppy disk, a CD-ROM, DVD-ROM, or USB key or more generally by any removable memory medium or via a network connection.
  • a reading device for example a floppy disk drive a CD-ROM drive, DVD-ROM, or connection ports for reading the instructions of the method of processing a medium instructions (not shown), such as a floppy disk, a CD-ROM, DVD-ROM, or USB key or more generally by any removable memory medium or via a network connection.
  • the storage unit 7 is connected to the control unit 6 for the recording of the acquired parameters and images. It is possible to provide that the storage unit 7 is located inside the control unit 6 or outside.
  • the storage unit 7 may be formed by a hard disk or SSD, or any other removable and rewritable storage means (USB sticks, memory cards etc.).
  • the storage unit 7 may be a ROM / RAM memory of the control unit 6, a USB key, a memory card, a memory of a central server.
  • the display unit 8 is connected to the control unit 6 for displaying the acquired images and / or information on the control parameters of the acquisition.
  • the display unit 8 may be for example a computer screen, a monitor, a flat screen, a plasma screen or any other type of display device of known type.
  • Such a display unit 8 allows a practitioner to control the acquisition of radiological images.
  • the medical imaging system 100 is coupled to a processing system 200.
  • the processing system 200 comprises a calculation unit 9 and a storage unit 10.
  • the processing system 200 receives images acquired and stored in the storage unit 4 of the medical imaging system 100 from which it performs a number of treatments (see below).
  • the data transmission from the storage unit 4 of the medical imaging system 100 to the computing unit 9 of the processing system 200 can be done through an internal or external computer network or with the aid of any memory medium adequate physical data such as floppy disks, CD-ROM, DVD-ROM, external hard disk, USB stick, SD card, etc.
  • the computing unit 9 is for example a computer (s), a processor (s), a microcontroller (s), a microcomputer (s), an automaton (s) programmable (s), specific integrated circuit (s), other programmable circuits, or other devices that include a computer such as a workstation.
  • the computer 9 may comprise a reading device (not shown), for example a floppy disk drive, a CD-ROM or DVD-ROM reader, or connection ports for reading the instructions of the processing method of a computer.
  • instruction medium such as a floppy disk, a CD-ROM, a DVD-ROM or a USB key or more generally by any removable memory medium or via a network connection.
  • the processing system comprises a storage unit 11 for storing the data generated by the calculation unit 9.
  • the calculation unit 9 can be connected to the display unit 8 (as on the figure 1 ) or to another display unit (not shown).
  • FIG. 2 schematically illustrates the steps of the method.
  • the radiological image processing method uses two radiological images I 1 , I 2 of a region of interest of a patient, into which a tool has been previously introduced. We consider in the following an elongated tool.
  • Such a tool is for example a guide wire, a catheter or the combination of several of them.
  • the guide wire which is intended to facilitate the introduction of a stent.
  • the first image I 1 corresponds to a radiological image of the region of interest in which a contrast product has been injected.
  • a contrast product is for example iodine and the region of interest is typically the coronary region of a patient to be treated.
  • the second image I 2 corresponds to a radiological image of the region of interest, without contrast product or with a minimum amount of contrast product.
  • minimal amount of contrast medium is meant a quantity of contrast medium which makes it possible to visualize the tool without being masked by the arteries.
  • the first and second images I 1 , I 2 can be obtained by means of acquisition implemented during the radiological image processing method or else obtained from a storage unit of the medical imaging system.
  • first and second images I 1 , I 2 are derived from acquisitions implemented using the medical imaging system described above for a given angulation, that is to say the orientation of the source. X-ray compared to normal to the support on which the patient is disposed.
  • the first and second images I 1 , I 2 are 2D projection images.
  • a set of images is defined as being the pair constituted by the first and second images acquired for a given angulation.
  • This step consists in extracting and isolating, from the first image I 1 and thanks to the injected contrast product, the arteries of the patient.
  • the figure 3 schematically illustrates an example of a first segmented image I 1 'having an array 101 of arteries visualized patient, an artery 103 having a constriction 102 corresponding to a lesion to be detected.
  • This step S4 consists of extracting and isolating, from the region of interest imaged without contrast product, the tool inserted into an artery of interest to the patient.
  • the figure 4 schematically illustrates an example of a second segmented image I 2 'having the same network 101 as that of the first segmented image I 1 ' illustrated in broken lines and a tool 201, here a guide wire inserted in an artery of the network 101 of arteries.
  • a tool 201 here a guide wire inserted in an artery of the network 101 of arteries.
  • the network 101 is shown here as an indication.
  • segmenting an image is a technique well known to those skilled in the art and will not be described in more detail.
  • This step S5 consists in defining for each artery a line Ci, for example a central line defining an axis of symmetry of an artery.
  • central lines Ci are for example implemented by means of a technique described in the document Karl Krissian, Gregory Malandain, Nicholas Ayache, Régis Vaillant and Yves Trousset: "Model-Based Detection of Tubular Structures in 3D Images", Computer Vision and Image Understanding, Vol. 80, num. 2, p. 130-171, 2000 .
  • This step S5 consists in detecting an artery of interest, that is to say the artery into which the tool has been inserted.
  • the detection of the artery of interest is carried out starting from the second image I 2 'and from the image I 3 '.
  • Such detection is implemented by means of a distance criterion between the tool 201 isolated and detected in the second segmented image I 2 'and the central lines Ci defined.
  • the artery of interest corresponds to the artery for which the distance between the tool and the central line C is minimal.
  • a method of quantitative analysis of coronary lesions ( Quantitatvie Coronary Analysis , QCA) is applied to the artery of interest.
  • QCA analysis is based on a clinically validated algorithm for contour detection and allows for the determination of occlusion percentage, occlusion of diameter, and size of normal artery and stenotic artery.
  • such an algorithm analyzes the artery all along the central line C and in particular determines at each point of the central line the apparent diameter of the artery.
  • the variations of this diameter and in particular the decreases are indicators of the presence of pathology such as arterial stenosis.
  • Quantification consists in determining such a decrease by a percentage relative to a zone of normal diameter.
  • the method described above can be applied to several 2D projection images taken for different angulations.
  • 3D reconstruction of known type and applicable to lines can be obtained 3D lines that describe the geometry of the artery. More particularly it is possible to obtain a 3D view of the artery of interest.
  • the radiological image processing method can advantageously be implemented in the form of a computer program comprising machine instructions for carrying out the method.

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  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Claims (11)

  1. Verfahren zur Verarbeitung von Strahlenbildern von einem Bereich eines Patienten von Interesse, wobei die Strahlenbilder Bilder zweidimensionaler Projektion sind, in welchen ein längliches Instrument im Vorfeld in eine Arterie eingesetzt wurde, wobei das Verfahren die folgenden Schritte aufweist:
    - Erlangung (S1, S2) von zumindest einem Satz Bilder, der durch ein erstes Bild (I1) und durch ein zweites Bild (I2) des Bereichs von Interesse gebildet wird, wobei das erste Bild (I1) ein Bild von dem Bereich von Interesse ist, in welchem ein Kontrastmittel im Vorfeld injiziert wurde, wobei das zweite Bild ein Bild von dem Bereich von Interesse ohne Kontrastmittel oder mit einer minimalen Menge von Kontrastmittel ist, wobei jeder Satz einer vorgegebenen Ausrichtung entspricht;
    - wobei das Verfahren für jeden Satz die folgenden Schritte aufweist:
    - Segmentierung (S3) des ersten Bildes (I1), um eine Vielzahl von Arterien des Bereichs von Interesse zu erfassen;
    - Segmentierung (S4) des zweiten Bildes (I2), um das Instrument zu erfassen und zu isolieren;
    - Festlegung (S5) einer Vielzahl von Linien (Ci) in dem ersten segmentierten Bild, wobei jede Linie (Ci) eine Arterie festlegt;
    - Bestimmung (S6), auf der Grundlage des zweiten segmentierten Bildes und der festgelegten Linien, einer Arterie von Interesse entsprechend einer Arterie, in welcher das Instrument eingesetzt wurde, wobei eine Linie (C7) der Arterie von Interesse am nächsten zu dem Instrument ist;
    - Anwenden (S7) von einem Algorithmus zur quantitativen Analyse von Koronarverletzungen bei der Arterie von Interesse, um eine Verletzung der Arterie von Interesse zu erfassen.
  2. Verfahren gemäß dem vorangehenden Anspruch, bei welchem das Anwenden des Algorithmus zur quantitativen Analyse unter Verwendung von entlang der Linie der Arterie von Interesse platzierten Punkten verwirklicht wird.
  3. Verfahren gemäß einem der vorangehenden Ansprüche, bei welchem der Schritt der Bestimmung der Arterie von Interesse das Anwenden eines Abstandskriteriums aufweist, das den euklidischen Abstand einer Linie einer Arterie und eine Ermittlung des Ausrichtungsunterschieds des Instruments mit dieser Linie entlang der Kurve, die das längliche Werkzeug festlegt, kombiniert.
  4. Verfahren gemäß einem der vorangehenden Ansprüche, bei welchem die die Arterien festlegenden Linien Zentrallinien sind, die jeweils eine Symmetrieachse von einer Arterie festlegen.
  5. Verfahren gemäß einem der vorangehenden Ansprüche, wobei zumindest zwei Sätze von Bildern (I1, I2) erlangt werden, wobei das Verfahren nach der Bestimmung der Arterie von Interesse für jeden Satz einen Schritt der dreidimensionalen Rekonstruktion zum Erlangen von einem dreidimensionalen Bild der Arterie von Interesse aufweist.
  6. Verfahren gemäß Anspruch 5, wobei der Algorithmus zur quantitativen Analyse an der dreidimensionalen Arterie von Interesse angewandt wird.
  7. Verfahren gemäß einem der Ansprüche 1 bis 3, wobei eine Sequenz von Sätzen von Bildern erlangt wird und wobei die Identifikation der Arterie von Interesse an jeder erfassten Arterie von Interesse für jeden Satz angewandt wird, um ein zweidimensionales Bewegungsfeld der Linie der Arterie von Interesse zu erlangen.
  8. Verfahren gemäß einem der Ansprüche 1 bis 3, wobei eine Vielzahl von Sequenzen von Sätzen von Bildern erlangt wird und wobei der Algorithmus zur quantitativen Analyse an jedem Satz von Bildern angewandt wird, um das Bewegungsfeld, das in das Bild der Linie der Arterie von Interesse projiziert wird, zu erhalten.
  9. Verfahren gemäß einem der vorangehenden Ansprüche, wobei die erhaltenen Strahlenbilder Bilder sind, die im Vorfeld erlangt werden und in einer Speichereinheit des medizinischen Bildgebungssystems gespeichert sind.
  10. Medizinisches Bildgebungssystem mit Mitteln zum Durchführen eines Verfahrens gemäß einem der vorangehenden Ansprüche.
  11. Computerprogramm, dadurch gekennzeichnet, dass es Maschinenanweisungen zur Ausführung eines Verfahrens gemäß einem der Ansprüche 1 bis 9, wenn es von einem Computer ausgeführt werden, aufweist.
EP10306249.3A 2010-11-12 2010-11-12 Verarbeitungsverfahren von Röntgenbildern zur Erkennung einer Stenose Not-in-force EP2453408B1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP10306249.3A EP2453408B1 (de) 2010-11-12 2010-11-12 Verarbeitungsverfahren von Röntgenbildern zur Erkennung einer Stenose
US13/290,450 US8880148B2 (en) 2010-11-12 2011-11-07 Treatment process of radiological images for detection of stenosis
CN201110387801.4A CN102592274B (zh) 2010-11-12 2011-11-11 用于狭窄检测的放射图像的处理过程

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10306249.3A EP2453408B1 (de) 2010-11-12 2010-11-12 Verarbeitungsverfahren von Röntgenbildern zur Erkennung einer Stenose

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EP2453408A1 EP2453408A1 (de) 2012-05-16
EP2453408B1 true EP2453408B1 (de) 2013-06-05

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Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8542900B2 (en) 2007-03-08 2013-09-24 Sync-Rx Ltd. Automatic reduction of interfering elements from an image stream of a moving organ
US9968256B2 (en) 2007-03-08 2018-05-15 Sync-Rx Ltd. Automatic identification of a tool
JP5639764B2 (ja) 2007-03-08 2014-12-10 シンク−アールエックス，リミティド 運動する器官と共に使用するイメージング及びツール
US11197651B2 (en) 2007-03-08 2021-12-14 Sync-Rx, Ltd. Identification and presentation of device-to-vessel relative motion
WO2014002095A2 (en) 2012-06-26 2014-01-03 Sync-Rx, Ltd. Flow-related image processing in luminal organs
US11064964B2 (en) 2007-03-08 2021-07-20 Sync-Rx, Ltd Determining a characteristic of a lumen by measuring velocity of a contrast agent
US10716528B2 (en) 2007-03-08 2020-07-21 Sync-Rx, Ltd. Automatic display of previously-acquired endoluminal images
US9375164B2 (en) 2007-03-08 2016-06-28 Sync-Rx, Ltd. Co-use of endoluminal data and extraluminal imaging
US9629571B2 (en) 2007-03-08 2017-04-25 Sync-Rx, Ltd. Co-use of endoluminal data and extraluminal imaging
ES2450391T3 (es) 2008-06-19 2014-03-24 Sync-Rx, Ltd. Avance progresivo de un instrumento médico
US10362962B2 (en) 2008-11-18 2019-07-30 Synx-Rx, Ltd. Accounting for skipped imaging locations during movement of an endoluminal imaging probe
US8855744B2 (en) 2008-11-18 2014-10-07 Sync-Rx, Ltd. Displaying a device within an endoluminal image stack
US9974509B2 (en) 2008-11-18 2018-05-22 Sync-Rx Ltd. Image super enhancement
US9144394B2 (en) 2008-11-18 2015-09-29 Sync-Rx, Ltd. Apparatus and methods for determining a plurality of local calibration factors for an image
US9101286B2 (en) 2008-11-18 2015-08-11 Sync-Rx, Ltd. Apparatus and methods for determining a dimension of a portion of a stack of endoluminal data points
US9095313B2 (en) 2008-11-18 2015-08-04 Sync-Rx, Ltd. Accounting for non-uniform longitudinal motion during movement of an endoluminal imaging probe
US11064903B2 (en) 2008-11-18 2021-07-20 Sync-Rx, Ltd Apparatus and methods for mapping a sequence of images to a roadmap image
EP2723231A4 (de) 2011-06-23 2015-02-25 Sync Rx Ltd Luminale hintergrundreinigung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002032307A1 (en) 2000-10-18 2002-04-25 Paieon Inc. Method and system for measuring dimensions of an organ
US6718193B2 (en) 2000-11-28 2004-04-06 Ge Medical Systems Global Technology Company, Llc Method and apparatus for analyzing vessels displayed as unfolded structures
JP5129480B2 (ja) 2003-09-25 2013-01-30 パイエオン インコーポレイテッド 管状臓器の３次元再構成を行うシステム及び血管撮像装置の作動方法
US20070003121A1 (en) * 2004-01-15 2007-01-04 Koninklijke Philips Electronic, N.V. Automatic contrast medium control in images

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CN102592274A (zh) 2012-07-18
US8880148B2 (en) 2014-11-04
US20120123238A1 (en) 2012-05-17
EP2453408A1 (de) 2012-05-16

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