EP2443259A4 - BIOMARKERS FOR AUTISM AND USES THEREOF - Google Patents

BIOMARKERS FOR AUTISM AND USES THEREOF

Info

Publication number: EP2443259A4
Authority: EP; European Patent Office
Prior art keywords: autism; biomarkers
Prior art date: 2009-06-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP10789901A

Other languages

German (de)

French (fr)

Other versions

EP2443259A1 (en

Inventor

W Ian Lipkin

Mady Hornig

Brent L Williams

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Columbia University in the City of New York

Original Assignee

Columbia University in the City of New York

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-06-16

Filing date

2010-05-10

Publication date

2012-10-10

2010-05-10 Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York

2012-04-25 Publication of EP2443259A1 publication Critical patent/EP2443259A1/en

2012-10-10 Publication of EP2443259A4 publication Critical patent/EP2443259A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Analytical Chemistry (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Pathology (AREA)
Immunology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP10789901A 2009-06-16 2010-05-10 BIOMARKERS FOR AUTISM AND USES THEREOF Withdrawn EP2443259A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US18760609P	2009-06-16	2009-06-16
PCT/US2010/034254 WO2010147714A1 (en)	2009-06-16	2010-05-10	Autism-associated biomarkers and uses thereof

Publications (2)

Publication Number	Publication Date
EP2443259A1 EP2443259A1 (en)	2012-04-25
EP2443259A4 true EP2443259A4 (en)	2012-10-10

Family

ID=43356678

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP10789901A Withdrawn EP2443259A4 (en)	2009-06-16	2010-05-10	BIOMARKERS FOR AUTISM AND USES THEREOF

Country Status (2)

Country	Link
EP (1)	EP2443259A4 (en)
WO (1)	WO2010147714A1 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9707207B2 (en)	2010-05-26	2017-07-18	The United States Of America As Represented By The Department Of Veterans Affairs	Method for diagnosing, preventing, and treating neurological diseases
GB201112091D0 (en)	2011-07-14	2011-08-31	Gt Biolog Ltd	Bacterial strains isolated from pigs
EP3323897A1 (en) *	2011-10-03	2018-05-23	Celmatix, Inc.	Methods and devices for assessing risk to a putative offspring of developing a condition
GB201117313D0 (en)	2011-10-07	2011-11-16	Gt Biolog Ltd	Bacterium for use in medicine
WO2013139861A1 (en) *	2012-03-20	2013-09-26	Luc Montagnier	Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
EP2877605A4 (en) *	2012-07-26	2016-03-02	Univ California	SCREENING, DIAGNOSIS AND PROGNOSIS OF AUTISM AND OTHER DEVELOPMENTAL DISORDERS
US9177098B2 (en)	2012-10-17	2015-11-03	Celmatix Inc.	Systems and methods for determining the probability of a pregnancy at a selected point in time
US10162800B2 (en)	2012-10-17	2018-12-25	Celmatix Inc.	Systems and methods for determining the probability of a pregnancy at a selected point in time
US9836577B2 (en)	2012-12-14	2017-12-05	Celmatix, Inc.	Methods and devices for assessing risk of female infertility
GB201306536D0 (en)	2013-04-10	2013-05-22	Gt Biolog Ltd	Polypeptide and immune modulation
AU2015289464A1 (en)	2014-07-17	2017-02-02	Celmatix Inc.	Methods and systems for assessing infertility and related pathologies
JP6427278B2 (en)	2014-12-23	2018-11-21	フォーディーファーマリサーチリミテッド４ＤＰｈａｒｍａＲｅｓｅａｒｃｈＬｉｍｉｔｅｄ	pirin polypeptide and immune modulation
SG11201704811YA (en)	2014-12-23	2017-07-28	4D Pharma Res Ltd	Immune modulation
PE20180243A1 (en)	2015-06-15	2018-01-31	4D Pharma Res Ltd	COMPOSITIONS INCLUDING BACTERIAL STRAINS
LT3307288T (en)	2015-06-15	2019-10-10	4D Pharma Research Limited	COMPOSITIONS INCLUDING BACTERIAL STRAINS
MA41010B1 (en)	2015-06-15	2020-01-31	4D Pharma Res Ltd	Compositions comprising bacterial strains
MA41060B1 (en)	2015-06-15	2019-11-29	4D Pharma Res Ltd	Compositions comprising bacterial strains
SG10201912319SA (en)	2015-06-15	2020-02-27	4D Pharma Res Ltd	Compositions comprising bacterial strains
GB201520497D0 (en)	2015-11-20	2016-01-06	4D Pharma Res Ltd	Compositions comprising bacterial strains
DK3209310T3 (en)	2015-11-20	2018-04-16	4D Pharma Res Ltd	COMPOSITIONS COMPREHENSIVE BAKERY STUES
GB201520638D0 (en)	2015-11-23	2016-01-06	4D Pharma Res Ltd	Compositions comprising bacterial strains
GB201520631D0 (en)	2015-11-23	2016-01-06	4D Pharma Res Ltd	Compositions comprising bacterial strains
RS58869B1 (en)	2016-03-04	2019-08-30	4D Pharma Plc	Compositions comprising bacterial blautia strains for treating visceral hypersensitivity
GB201612191D0 (en)	2016-07-13	2016-08-24	4D Pharma Plc	Compositions comprising bacterial strains
US11946927B2 (en)	2016-03-14	2024-04-02	Musidora Biotechnology Llc	Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment
US10295527B2 (en)	2016-03-14	2019-05-21	Bruce Yacyshyn	Process and system for predicting responders and non-responders to mesalamine treatment of ulcerative colitis
TW201821093A (en)	2016-07-13	2018-06-16	英商４Ｄ製藥有限公司	Composition comprising a bacterial strain
GB201621123D0 (en)	2016-12-12	2017-01-25	4D Pharma Plc	Compositions comprising bacterial strains
MA48939B1 (en)	2017-05-22	2021-06-30	4D Pharma Res Ltd	Compositions comprising bacterial strains
TW201907931A (en)	2017-05-24	2019-03-01	英商4D製藥研究有限公司	Composition comprising a bacterial strain
KR102008451B1 (en) *	2017-05-26	2019-08-07	주식회사 엠디헬스케어	Method for diagnosis of Autism using analysis of bacteria metagenome
JP6884889B2 (en)	2017-06-14	2021-06-09	フォーディーファーマリサーチリミテッド４ＤＰｈａｒｍａＲｅｓｅａｒｃｈＬｉｍｉｔｅｄ	Compositions Containing Bacterial Strains
KR102521444B1 (en)	2017-06-14	2023-04-12	4디 파마 리서치 리미티드	Compositions containing bacterial strains
WO2018229236A2 (en)	2017-06-14	2018-12-20	4D Pharma Research Limited	Compositions comprising bacterial strains
US11376289B2 (en) *	2018-05-31	2022-07-05	Bgi Shenzhen	Composition and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006060414A2 (en) *	2004-12-01	2006-06-08	Kirkman Group, Inc.	Compositions and methods for the treatment of autism
US7091182B2 (en) *	1997-05-19	2006-08-15	Repligen Corporation	Method for assisting in differential diagnosis and treatment of autistic syndromes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040170617A1 (en) *	2000-06-05	2004-09-02	Finegold Sydney M.	Method of treating diseases associated with abnormal gastrointestinal flora
US7972601B2 (en) *	2004-05-11	2011-07-05	The Regents Of The University Of California	Method of promoting delivery of an antioxidant agent to a cell expression neuroligin
EP1848826A2 (en) *	2005-02-17	2007-10-31	Integragen	Human autism susceptibility gene encoding a kinase and uses thereof

2010
- 2010-05-10 WO PCT/US2010/034254 patent/WO2010147714A1/en active Application Filing
- 2010-05-10 EP EP10789901A patent/EP2443259A4/en not_active Withdrawn

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7091182B2 (en) *	1997-05-19	2006-08-15	Repligen Corporation	Method for assisting in differential diagnosis and treatment of autistic syndromes
WO2006060414A2 (en) *	2004-12-01	2006-06-08	Kirkman Group, Inc.	Compositions and methods for the treatment of autism

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HORVATH K ET AL: "Gastrointestinal abnormalities in children with autistic disorder", JOURNAL OF PEDIATRICS, vol. 135, no. 5, 1 November 1999 (1999-11-01), MOSBY-YEAR BOOK, ST. LOUIS, MO, US, pages 559 - 563, XP027314235, ISSN: 0022-3476, [retrieved on 19991101] *
See also references of WO2010147714A1 *
WILLIAMS B T ET AL.: "Impaired carbohydrate digestion and transport ands mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances", PLOS ONE, vol. 6, no. 9, E24585, September 2011 (2011-09-01), pages 1 - 21, XP002682053 *

Also Published As

Publication number	Publication date
EP2443259A1 (en)	2012-04-25
WO2010147714A1 (en)	2010-12-23

Publication	Publication Date	Title
EP2443259A4 (en)	2012-10-10	BIOMARKERS FOR AUTISM AND USES THEREOF
EP2443459A4 (en)	2013-09-18	CONNECTION ARRANGEMENTS FOR SAMPLE PROFILE
EP2340506A4 (en)	2012-02-15	BIOMARKER FOR LUNG CANCER AND USE
EP2593567A4 (en)	2013-12-11	BIOMARKERS FOR THE DIAGNOSIS OF STROKE AND THEIR CAUSES
EP2376105A4 (en)	2012-10-17	NKG2D-FC FOR IMMUNOTHERAPY
BRPI1009269A2 (en)	2017-09-12	tissue-specific biomarkers of aging.
EP2602143A4 (en)	2013-09-04	COOLING STRUCTURE FOR VEHICLES
EP2708420A4 (en)	2015-05-27	OPERATING DEVICE AND ALARM DEVICE FOR AN AUTOMOTIVE INSTRUMENT
BRPI0920069A2 (en)	2017-06-06	biomarkers
EP2265642A4 (en)	2012-05-02	BIOMARKERS
EP2399920A4 (en)	2012-08-15	FLUORESCENCE PROBE FOR PROTEASE MEASUREMENT
AT10812U2 (en)	2009-10-15	TEST ARRANGEMENT
AT10813U2 (en)	2009-10-15	TEST ARRANGEMENT
EP2387618A4 (en)	2012-10-10	BIOMARKER PANEL FOR THE DIAGNOSIS AND PREDICTION OF TRANSPLANT DISCHARGE
EP2418899A4 (en)	2016-06-29	PROCESSING PROCESSES FOR GROUP PROCESSING
EP2265950A4 (en)	2011-08-17	Detection of biomarkers and biomarker complexes
PT2507635E (en)	2015-02-24	Biochemical serum biomarker
EP2263086A4 (en)	2012-10-17	BIOMARKERS
EP2382471A4 (en)	2012-09-05	MICROARRAYS FOR ALLERGEN SPECIFIC IGE
DE112010001205A5 (en)	2012-05-16	Adapter for carrier profiles
EP2300624A4 (en)	2012-11-28	BIOMARKERS FOR PAIN-BANDED DISCS AND METHOD OF USE THEREOF
GB0921329D0 (en)	2010-01-20	Biomarker
EP2427770A4 (en)	2012-11-28	TEST STRIPS FOR LATER FLOW TEST AND MANUFACTURING METHOD THEREFOR
EP2415870A4 (en)	2012-11-28	RNAI MOLECULE FOR THYMIDYLATE SYNTHASE AND USES THEREOF
AT508477A3 (en)	2011-04-15	PIPELINE INSPECTION UNIT

Legal Events

Date	Code	Title	Description
2012-03-23	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2012-04-25	17P	Request for examination filed	Effective date: 20111214
2012-04-25	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
2012-09-19	DAX	Request for extension of the european patent (deleted)
2012-10-03	RIC1	Information provided on ipc code assigned before grant	Ipc: C12Q 1/68 20060101AFI20120827BHEP
2012-10-10	A4	Supplementary search report drawn up and despatched	Effective date: 20120911
2012-10-10	RIC1	Information provided on ipc code assigned before grant	Ipc: C12Q 1/68 20060101AFI20120903BHEP
2016-04-27	17Q	First examination report despatched	Effective date: 20160331
2017-12-15	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2018-01-17	18D	Application deemed to be withdrawn	Effective date: 20170804