EP2323679A4 - CLIP HEMMER AND METHOD FOR MODULATING THE IMMUNE FUNCTION - Google Patents
CLIP HEMMER AND METHOD FOR MODULATING THE IMMUNE FUNCTIONInfo
- Publication number
- EP2323679A4 EP2323679A4 EP09800699A EP09800699A EP2323679A4 EP 2323679 A4 EP2323679 A4 EP 2323679A4 EP 09800699 A EP09800699 A EP 09800699A EP 09800699 A EP09800699 A EP 09800699A EP 2323679 A4 EP2323679 A4 EP 2323679A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hemmer
- modulating
- clip
- immune function
- immune
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13155864.5A EP2633864A1 (en) | 2008-07-25 | 2009-07-23 | Clip inhibitors and methods of modulating immune function |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13594208P | 2008-07-25 | 2008-07-25 | |
PCT/US2009/004328 WO2010011347A2 (en) | 2008-07-25 | 2009-07-23 | Clip inhibitors and methods of modulating immune function |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2323679A2 EP2323679A2 (en) | 2011-05-25 |
EP2323679A4 true EP2323679A4 (en) | 2012-08-22 |
Family
ID=41570789
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13155864.5A Withdrawn EP2633864A1 (en) | 2008-07-25 | 2009-07-23 | Clip inhibitors and methods of modulating immune function |
EP09800699A Withdrawn EP2323679A4 (en) | 2008-07-25 | 2009-07-23 | CLIP HEMMER AND METHOD FOR MODULATING THE IMMUNE FUNCTION |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13155864.5A Withdrawn EP2633864A1 (en) | 2008-07-25 | 2009-07-23 | Clip inhibitors and methods of modulating immune function |
Country Status (4)
Country | Link |
---|---|
EP (2) | EP2633864A1 (en) |
AU (1) | AU2009274512A1 (en) |
CA (1) | CA2737146A1 (en) |
WO (1) | WO2010011347A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
WO2015035414A1 (en) * | 2013-09-09 | 2015-03-12 | The Texas A&M University System | Treating neurological disorders |
EP3517117A1 (en) * | 2018-01-30 | 2019-07-31 | Medizinische Universität Wien | Medicament for prevention or treatment of rhinovirus infection |
US20230226135A9 (en) * | 2019-07-19 | 2023-07-20 | Bcell Solutions, Inc. | Acetylcholine modulation of immune function |
CA3158336A1 (en) * | 2019-09-20 | 2021-03-25 | Michiko Koga | Peptide, and cell fusion agent and pharmaceutical composition for cancer therapy containing said peptide |
EP3818989A1 (en) * | 2020-03-12 | 2021-05-12 | Universität Greifswald | Peptides and oligonucleotides for a sars-cov-2 vaccine |
Citations (3)
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WO2004043361A2 (en) * | 2002-11-08 | 2004-05-27 | Genentech, Inc. | Compositions and methods for the treatment of natural killer cell related diseases |
WO2005079523A2 (en) * | 2004-02-18 | 2005-09-01 | University Of Georgia Research Foundation, Inc. | Novel teleost derived antimicrobal polypeptides |
WO2009055005A2 (en) * | 2007-10-23 | 2009-04-30 | The Regents Of The University Of Colorado | Competitive inhibitors of invariant chain expression and/or ectopic clip binding |
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US565354A (en) | 1896-08-04 | James h | ||
US1164308A (en) | 1914-11-02 | 1915-12-14 | Nils Nilson | Traction-plow. |
US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
US4415553A (en) | 1973-08-06 | 1983-11-15 | Dso "Pharmachim" | Compositions, processes for their preparation and method for treatment of neoplasms |
US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
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US5520914A (en) | 1987-08-06 | 1996-05-28 | President And Fellows Of Harvard College | Antibodies to angiogenin: immunotherapeutic agents |
US5606040A (en) | 1987-10-30 | 1997-02-25 | American Cyanamid Company | Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group |
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GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US5211657A (en) | 1988-11-07 | 1993-05-18 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides |
US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
DE3920358A1 (en) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE |
CA2039718C (en) | 1989-08-31 | 2003-02-25 | John J. Rossi | Chimeric dna-rna catalytic sequences |
US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
US5972922A (en) | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
JP3257675B2 (en) | 1990-10-12 | 2002-02-18 | マックス−プランク−ゲゼルシャフト ツール フェルデルング デル ビッセンシャフテン エー.ファウ. | Modified ribozyme |
DE4216134A1 (en) | 1991-06-20 | 1992-12-24 | Europ Lab Molekularbiolog | SYNTHETIC CATALYTIC OLIGONUCLEOTIDE STRUCTURES |
JPH07501451A (en) | 1991-11-25 | 1995-02-16 | エンゾン・インコーポレイテッド | Multivalent antigen binding protein |
US5407686A (en) | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
US5652094A (en) | 1992-01-31 | 1997-07-29 | University Of Montreal | Nucleozymes |
DE69333082T2 (en) | 1992-02-11 | 2004-05-06 | Cell Genesys, Inc., Foster City | OBTAINING HOMOZYGOTEM BY TARGETED GENETIC EVENTS |
HUT72993A (en) | 1992-08-19 | 1996-06-28 | Merrell Dow Pharma | Process to prepare phatmaceutical compns. contg antiangiogenic oligomers |
US5792771A (en) | 1992-11-13 | 1998-08-11 | Sugen, Inc. | Quinazoline compounds and compositions thereof for the treatment of disease |
DE69303494T2 (en) | 1992-11-13 | 1997-01-16 | Idec Pharma Corp | THERAPEUTIC USE OF CHIMERIC AND LABELED ANTIBODIES AGAINST HUMAN B LYMPHOCYTIC LIMITED DIFFERENTIATION ANTIQUES FOR THE TREATMENT OF B CELL LYMPHOMA |
US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
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US5716981A (en) | 1993-07-19 | 1998-02-10 | Angiogenesis Technologies, Inc. | Anti-angiogenic compositions and methods of use |
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US5753230A (en) | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
US5534615A (en) | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
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US5773001A (en) | 1994-06-03 | 1998-06-30 | American Cyanamid Company | Conjugates of methyltrithio antitumor agents and intermediates for their synthesis |
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US5712171A (en) | 1995-01-20 | 1998-01-27 | Arqule, Inc. | Method of generating a plurality of chemical compounds in a spatially arranged array |
US5696092A (en) | 1995-03-07 | 1997-12-09 | George Washington University | Methods and compositions for inhibiting metastasis of epithelial cell-derived cancers |
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US6245904B1 (en) * | 1995-09-14 | 2001-06-12 | The University Of Tubingen | Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific T-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide |
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EP0886641A2 (en) | 1996-01-16 | 1998-12-30 | Ribozyme Pharmaceuticals, Inc. | Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules |
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-
2009
- 2009-07-23 EP EP13155864.5A patent/EP2633864A1/en not_active Withdrawn
- 2009-07-23 AU AU2009274512A patent/AU2009274512A1/en not_active Abandoned
- 2009-07-23 WO PCT/US2009/004328 patent/WO2010011347A2/en active Application Filing
- 2009-07-23 EP EP09800699A patent/EP2323679A4/en not_active Withdrawn
- 2009-07-23 CA CA2737146A patent/CA2737146A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004043361A2 (en) * | 2002-11-08 | 2004-05-27 | Genentech, Inc. | Compositions and methods for the treatment of natural killer cell related diseases |
WO2005079523A2 (en) * | 2004-02-18 | 2005-09-01 | University Of Georgia Research Foundation, Inc. | Novel teleost derived antimicrobal polypeptides |
WO2009055005A2 (en) * | 2007-10-23 | 2009-04-30 | The Regents Of The University Of Colorado | Competitive inhibitors of invariant chain expression and/or ectopic clip binding |
Non-Patent Citations (8)
Title |
---|
ADAMS SHARLENE ET AL: "Biological activity and therapeutic potential of homologs of an Ii peptide which regulates antigenic peptide binding to cell surface MHC class II molecules", ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, ECV EDITIO CANTOR VERLAG, AULENDORF, DE, vol. 47, no. 9, 1 January 1997 (1997-01-01), pages 1069 - 1077, XP001526055, ISSN: 0004-4172 * |
CHRISTIE G ET AL: "Alzheimer's disease: correlation of the suppression of.beta.-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome", JOURNAL OF NEUROCHEMISTRY, WILEY INTERSCIENCE, NEW YORK, NY, US, vol. 73, no. 1, 1 January 1999 (1999-01-01), pages 195 - 204, XP002209921, ISSN: 0022-3042, DOI: 10.1046/J.1471-4159.1999.0730195.X * |
HILLMAN G G ET AL: "Generating MHC Class II+/Ii- phenotype after adenoviral delivery of both an expressible gene for MHC Class II inducer and an antisense Ii-RNA construct in tumor cells", GENE THERAPY, MACMILLAN PRESS LTD., BASINGSTOKE, GB, vol. 10, no. 17, 1 August 2003 (2003-08-01), pages 1512 - 1518, XP009160950, ISSN: 0969-7128 * |
HITZEL CHRISTOPH ET AL: "The invariant chain derived fragment clip is an efficient in vitro inhibitor of peptide binding to MHC class II molecules", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 33, no. 1, 1 January 1996 (1996-01-01), pages 25 - 31, XP009160759, ISSN: 0161-5890, [retrieved on 19990426], DOI: 10.1016/0161-5890(95)00131-X * |
LU XUEQING ET AL: "Suppression of major histocompatibility complex class II-associated invariant chain enhances the potency of an HIV gp120 DNA vaccine", IMMUNOLOGY, BLACKWELL PUBLISHING, OXFORD, GB, vol. 120, no. 2, 1 February 2007 (2007-02-01), pages 207 - 216, XP002612403, ISSN: 0019-2805, DOI: 10.1111/J.1365-2567.2006.02492.X * |
STEIN R ET AL: "CD74: A new candidate target for the immunotherapy of B-cell neoplasms", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 13, no. 18, 15 September 2007 (2007-09-15), pages 5556S - 5563S, XP002510850, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-07-1167 * |
WU S ET AL: "The MHC class II-associated invariant chain-derived peptide CLIP binds to the peptide-binding groove of class II molecules", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 33, no. 4-5, 1 March 1996 (1996-03-01), pages 371 - 377, XP027285074, ISSN: 0161-5890, [retrieved on 19960301] * |
XU MINZHEN ET AL: "Immunotherapy of cancer by antisense inhibition of Ii protein, an immunoregulator of antigen selection by MHC class II molecules", CURRENT OPINION IN MOLECULAR THERAPEUTICS, CURRENT DRUGS, LONDON, GB, vol. 6, no. 2, 1 April 2004 (2004-04-01), pages 160 - 165, XP009115265, ISSN: 1464-8431 * |
Also Published As
Publication number | Publication date |
---|---|
WO2010011347A2 (en) | 2010-01-28 |
EP2323679A2 (en) | 2011-05-25 |
WO2010011347A3 (en) | 2010-05-27 |
EP2633864A1 (en) | 2013-09-04 |
CA2737146A1 (en) | 2010-01-28 |
AU2009274512A1 (en) | 2010-01-28 |
WO2010011347A9 (en) | 2010-04-08 |
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