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EP2319623A3 - Metering device for liquids and method for metering liquids - Google Patents

Metering device for liquids and method for metering liquids Download PDF

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Publication number
EP2319623A3
EP2319623A3 EP10013402A EP10013402A EP2319623A3 EP 2319623 A3 EP2319623 A3 EP 2319623A3 EP 10013402 A EP10013402 A EP 10013402A EP 10013402 A EP10013402 A EP 10013402A EP 2319623 A3 EP2319623 A3 EP 2319623A3
Authority
EP
European Patent Office
Prior art keywords
syringe
pipette tip
controllable drive
releasing
holding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10013402A
Other languages
German (de)
French (fr)
Other versions
EP2319623A2 (en
EP2319623B1 (en
Inventor
Karl-Friedrich Andres
Peter Molitor
Peter Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf SE filed Critical Eppendorf SE
Publication of EP2319623A2 publication Critical patent/EP2319623A2/en
Publication of EP2319623A3 publication Critical patent/EP2319623A3/en
Application granted granted Critical
Publication of EP2319623B1 publication Critical patent/EP2319623B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0237—Details of electronic control, e.g. relating to user interface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B01L3/0279—Interchangeable or disposable dispensing tips co-operating with positive ejection means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/087—Ergonomic aspects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227—Details of motor drive means

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Dosiervorrichtung für Flüssigkeiten mit
- einem Grundkörper,
- am Grundkörper angeordneten Mitteln zum Halten mindestens einer Pipettenspitze mit ihrer oberen Öffnung in abdichtender Verbindung mit einer Durchgangsöffnung am Grundkörper und einer im Grundkörper angeordneten Verdrängungseinrichtung mit einer Verdrängungskammer, einem darin beweglich angeordneten Verdrängungsorgan und einer kommunizierenden Verbindung mit der Durchgangsöffnung oder
- am Grundkörper angeordneten Mitteln zum Halten mindestens einer Spritze mit einem Spritzenzylinder in lagefester Beziehung zum Grundkörper und mit einem in dem Spritzenzylinder verschiebbaren Spritzenkolben und mit einem mit dem Spritzenkolbenmechanisch kuppelbaren Kupplungsmittel im Grundkörper,
- am Grundkörper angeordneten Mitteln zum Lösen der Pipettenspitze oder Spritze von den Mitteln zum Halten mit einem manuell betätigbaren Betätigungsorgan zum Betätigen der Mittel zum Lösen, ohne das dabei das Verdrängungsorgan oder das Kupplungselement bewegt werden
- einem am Grundkörper angeordneten Sensor zum Erfassen einer Betätigung der Mittel zum Lösen oder des erfolgten Lösens der Pipettenspitze oder Spritze,
- einem ansteuerbaren Antrieb, der mit dem Verdrängungsorgan oder den Kupplungsmitteln wirkverbunden ist,
- Eingabemitteln zum Steuern des steuerbaren Antriebs,
- elektrischen Steuerungsmitteln, die mit dem steuerbaren Antrieb, den Eingabemitteln und dem Sensor elektrisch verbunden sind und die so beschaffen sind, dass der steuerbare Antrieb, wenn der Sensor eineDosing device for liquids with
a basic body,
- arranged on the base body means for holding at least one pipette tip with its upper opening in sealing connection with a passage opening on the base body and arranged in the body displacement device with a displacement chamber, a movable therein arranged displacement member and a communicating connection with the through hole or
- arranged on the body means for holding at least one syringe with a syringe barrel in positionally stable relationship to the body and with a displaceable in the syringe barrel syringe plunger and with a syringe piston mechanically coupled coupling agent in the body,
- Located on the body means for releasing the pipette tip or syringe from the means for holding with a manually operable actuator for actuating the means for releasing without the displacement member or the coupling element are moved
a sensor arranged on the main body for detecting an actuation of the means for releasing or disengaging the pipette tip or syringe,
a controllable drive, which is operatively connected to the displacement member or the coupling means,
Input means for controlling the controllable drive,
- Electrical control means which are electrically connected to the controllable drive, the input means and the sensor and which are arranged such that the controllable drive when the sensor is a

Betätigung der Mittel zum Lösen oder das erfolgte Lösen der Pipettenspitze oder Spritze erfasst, das Verdrängungsorgan oder die Kupplungsmittel in eine Grundposition verlagert.

Figure imgaf001
Figure imgaf002
Actuation of the means for loosening or the loosening of the pipette tip or syringe detected detected displaces the displacer or the coupling means in a basic position.
Figure imgaf001
Figure imgaf002
EP10013402.2A 2009-10-30 2010-10-07 Metering device for liquids and method for metering liquids Active EP2319623B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009051654A DE102009051654B4 (en) 2009-10-30 2009-10-30 Dosing device for liquids and method for dosing liquids
US26188409P 2009-11-17 2009-11-17

Publications (3)

Publication Number Publication Date
EP2319623A2 EP2319623A2 (en) 2011-05-11
EP2319623A3 true EP2319623A3 (en) 2012-12-12
EP2319623B1 EP2319623B1 (en) 2014-03-05

Family

ID=43828842

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10013402.2A Active EP2319623B1 (en) 2009-10-30 2010-10-07 Metering device for liquids and method for metering liquids

Country Status (5)

Country Link
US (1) US8570029B2 (en)
EP (1) EP2319623B1 (en)
JP (1) JP5509033B2 (en)
CN (1) CN102116654B (en)
DE (1) DE102009051654B4 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2681567B1 (en) 2011-03-03 2021-04-28 Life Technologies Corporation Sampling probes
WO2013166203A2 (en) * 2012-05-01 2013-11-07 Life Technologies Corporation Pippette devices, systems, and methods of use thereof
EP3088904A1 (en) * 2015-04-27 2016-11-02 Siemens Healthcare Diagnostics Products GmbH Method for checking the functionality of a washing station for pipette needles
EP3096148B1 (en) * 2015-05-20 2024-01-03 Siemens Healthcare Diagnostics Products GmbH Pipetting device
EP3335795B1 (en) 2016-12-16 2019-03-27 Eppendorf AG Method for metering liquid using a pipette and an injection and pipette for actuating an injection for dosing liquid
WO2018141898A1 (en) * 2017-02-03 2018-08-09 Eppendorf Ag Handheld fluid transfer apparatus, laboratory system comprising the handheld fluid transfer apparatus, and method for operating a handheld fluid transfer apparatus or the laboratory system
DE202017101009U1 (en) * 2017-02-23 2018-05-24 Brand Gmbh + Co Kg Attaching and detaching a piston-cylinder unit to or from a dispenser for receiving and dispensing fluid volumes
USD871606S1 (en) 2017-11-22 2019-12-31 Brand Gmbh + Co Kg Hand operated laboratory instrument
IT201900013110A1 (en) * 2019-07-26 2021-01-26 Giuseppe Zucca Apparatus and method for gravimetric dosing of liquid substances
EP3851191A1 (en) * 2020-01-17 2021-07-21 Eppendorf AG Plunger lift pipette, data processing apparatus and system and method for operating a plunger-lift pipette

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10257414A1 (en) * 2002-12-05 2004-06-24 Eppendorf Ag Electric motor-driven syringe dispenser, has a pump for driving a working piston-cylinder combination that is coupled to the syringe piston, with the pump driven by an electric motor
DE102004025588A1 (en) * 2004-05-25 2005-12-22 Lre Technology Partner Gmbh Holder for dosing tip, includes sensor arrangement detecting incorrect attachment of push-on tip to connecting section
US20090000350A1 (en) * 2007-06-29 2009-01-01 Rainin Instrument, Llc Hybrid manual-electronic pipette

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187990A (en) 1984-02-16 1993-02-23 Rainin Instrument Co., Inc. Method for dispensing liquids with a pipette with compensation for air pressure and surface tension
EP0197921A1 (en) * 1984-10-02 1986-10-22 DEVAUGHN, Donald H. Pipetting techniques using replaceable tips
FI852704L (en) * 1985-07-08 1987-01-09 Labsystems Oy ELDRIVEN PIPETT.
JPH06134323A (en) * 1992-10-27 1994-05-17 Daikin Ind Ltd Pipetta
DE4341229C2 (en) 1993-12-03 1995-09-07 Eppendorf Geraetebau Netheler Pipette system
JP2945848B2 (en) * 1995-04-12 1999-09-06 アロカ株式会社 Dispensing device
US5906795A (en) * 1996-04-08 1999-05-25 Sanyo Electric Co., Ltd. Pipetting apparatus
US5892161A (en) * 1997-09-09 1999-04-06 Tyco Group S.A.R.L. Transducer assembly for an electronically monitored mechanical pipette
DE29824951U1 (en) * 1998-07-09 2003-10-16 Eppendorf AG, 22339 Hamburg Pipette system for repetitive liquid dosing especially in scientific and medical laboratories
DE19850841A1 (en) 1998-11-04 2000-05-25 Eppendorf Geraetebau Netheler Method for operating an electronic dosing system and dosing system for carrying out the method
US6254832B1 (en) * 1999-03-05 2001-07-03 Rainin Instrument Co., Inc. Battery powered microprocessor controlled hand portable electronic pipette
JP2001183382A (en) * 1999-12-28 2001-07-06 Roche Diagnostics Gmbh Apparatus and method for confirming operation of dispensing machine
US6532837B1 (en) * 2000-02-03 2003-03-18 Rainin Instrument, Llc Pipette device with tip ejector utilizing stored energy
JP2001242185A (en) * 2000-02-29 2001-09-07 Hitachi Ltd Dispensing device and nozzle tip used for it
EP1438138B1 (en) * 2001-10-16 2010-09-08 Matrix Technologies Corporation Hand-held pipettor
US7429360B2 (en) * 2002-05-28 2008-09-30 Autogenomics, Inc. Level-controlled pipette for automated analytic devices
US6968749B2 (en) 2002-11-21 2005-11-29 Arise Biotech Corporation Portable automated pipette
DE10324956B4 (en) 2003-06-03 2008-03-13 Robert Bosch Gmbh probe
US7976793B2 (en) * 2003-11-27 2011-07-12 Gilson S.A.S. Electronic pipette
US7175813B2 (en) * 2003-12-31 2007-02-13 Rainin Instrument, Llc Volume adjustable manual pipette with quick set volume adjustment
DE102004003433B4 (en) * 2004-01-21 2006-03-23 Eppendorf Ag Pipetting device with a discharge device for pipette tips
DE102006024051A1 (en) 2006-05-23 2007-12-06 Eppendorf Ag Electronic dosing device for dosing liquids
DE102006031460B4 (en) 2006-07-07 2008-10-30 Eppendorf Ag pipetting
DE102006032859A1 (en) 2006-07-14 2008-01-17 Eppendorf Ag Electronic dosing device for dosing liquids
US9186677B2 (en) * 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US7540205B2 (en) * 2007-09-17 2009-06-02 Viaflo Corp. Electronic pipettor
DE102008048252A1 (en) 2008-09-12 2010-04-15 Eppendorf Ag pipetting
PL2933512T3 (en) 2014-04-14 2017-11-30 Abb Schweiz Ag Magnetic bearing arrangement and method of operating a magnetic bearing arrangement

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10257414A1 (en) * 2002-12-05 2004-06-24 Eppendorf Ag Electric motor-driven syringe dispenser, has a pump for driving a working piston-cylinder combination that is coupled to the syringe piston, with the pump driven by an electric motor
DE102004025588A1 (en) * 2004-05-25 2005-12-22 Lre Technology Partner Gmbh Holder for dosing tip, includes sensor arrangement detecting incorrect attachment of push-on tip to connecting section
US20090000350A1 (en) * 2007-06-29 2009-01-01 Rainin Instrument, Llc Hybrid manual-electronic pipette

Also Published As

Publication number Publication date
JP2011121047A (en) 2011-06-23
EP2319623A2 (en) 2011-05-11
DE102009051654B4 (en) 2013-01-03
CN102116654A (en) 2011-07-06
CN102116654B (en) 2014-10-01
EP2319623B1 (en) 2014-03-05
JP5509033B2 (en) 2014-06-04
US20110181272A1 (en) 2011-07-28
DE102009051654A1 (en) 2011-05-05
US8570029B2 (en) 2013-10-29

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