EP2236514A4 - Peptide artificiel et son utilisation - Google Patents

Peptide artificiel et son utilisation

Info

Publication number: EP2236514A4
Authority: EP; European Patent Office
Prior art keywords: artificial peptide; peptide; artificial
Prior art date: 2008-01-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP09704366A

Other languages

German (de)

English (en)

Other versions

EP2236514A1 (fr

EP2236514B1 (fr

Inventor

Tetsuhiko Yoshida

Nahoko Kobayashi

Junichi Masuda

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Toagosei Co Ltd

Original Assignee

Toagosei Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-25

Filing date

2009-01-23

Publication date

2011-03-30

2009-01-23 Application filed by Toagosei Co Ltd filed Critical Toagosei Co Ltd

2010-10-06 Publication of EP2236514A1 publication Critical patent/EP2236514A1/fr

2011-03-30 Publication of EP2236514A4 publication Critical patent/EP2236514A4/fr

2013-04-03 Application granted granted Critical

2013-04-03 Publication of EP2236514B1 publication Critical patent/EP2236514B1/fr

Status Active legal-status Critical Current

2029-01-23 Anticipated expiration legal-status Critical

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal

Landscapes

Genetics & Genomics (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

EP09704366A 2008-01-25 2009-01-23 Peptide artificiel et son utilisation Active EP2236514B1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2008014966		2008-01-25
PCT/JP2009/051082 WO2009093692A1 (fr)	2008-01-25	2009-01-23	Peptide artificiel et son utilisation

Publications (3)

Publication Number	Publication Date
EP2236514A1 EP2236514A1 (fr)	2010-10-06
EP2236514A4 true EP2236514A4 (fr)	2011-03-30
EP2236514B1 EP2236514B1 (fr)	2013-04-03

Family

ID=40901195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP09704366A Active EP2236514B1 (fr)	2008-01-25	2009-01-23	Peptide artificiel et son utilisation

Country Status (4)

Country	Link
US (1)	US20100297758A1 (fr)
EP (1)	EP2236514B1 (fr)
JP (1)	JP4573143B2 (fr)
WO (1)	WO2009093692A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010117078A1 (fr) *	2009-04-10	2010-10-14	東亞合成株式会社	Peptide induisant la differenciation neuronale et son utilisation
JP5709013B2 (ja) *	2009-04-10	2015-04-30	東亞合成株式会社	神経分化誘導ペプチド及びその利用
US8673845B2 (en)	2009-07-29	2014-03-18	Toagosei Co., Ltd.	Carrier peptide fragment and use thereof
JP5858285B2 (ja)	2009-07-29	2016-02-10	東亞合成株式会社	キャリアペプチドフラグメント及びその利用
WO2011052679A1 (fr) *	2009-11-02	2011-05-05	東亞合成株式会社	Peptide capable de promouvoir la prolifération cellulaire et son utilisation
JP5881272B2 (ja) *	2009-11-05	2016-03-09	東亞合成株式会社	細胞分化誘導ペプチド及びその利用
US8822408B2 (en)	2010-06-04	2014-09-02	Toagosei Co., Ltd.	Cell growth-promoting peptide and use thereof
US9238796B2 (en)	2010-06-04	2016-01-19	Toagosei Co. Ltd.	Cell growth-promoting peptide and use thereof
JP5967448B2 (ja) *	2011-05-02	2016-08-10	東亞合成株式会社	２型ｔｎｆ受容体の発現を誘導する合成ペプチド及びその利用
US9353350B2 (en)	2011-12-20	2016-05-31	Toagosei Co. Ltd.	Method for producing multipolar cell
WO2013094699A1 (fr) *	2011-12-20	2013-06-27	東亞合成株式会社	Procédé de production de cellules multipolaires
JP6156698B2 (ja) *	2011-12-20	2017-07-05	東亞合成株式会社	抗腫瘍ペプチド及びその利用
WO2013180011A1 (fr)	2012-05-28	2013-12-05	東亞合成株式会社	Peptide antibactérien et son utilisation
JP6311935B2 (ja)	2012-10-18	2018-04-18	東亞合成株式会社	２型ｔｎｆ受容体の発現を抑制する合成ペプチド及びその利用
JP6501122B2 (ja) *	2013-10-11	2019-04-17	東亞合成株式会社	ネスチン誘導合成ペプチド及びその利用
JP6490010B2 (ja)	2013-10-30	2019-03-27	東亞合成株式会社	ゲノム不安定なｉＰＳ細胞の除去方法および該方法に用いられる合成ペプチド
WO2015098962A1 (fr)	2013-12-25	2015-07-02	東亞合成株式会社	Procédé d'induction de la différenciation de cellules souches pluripotentes en cellules de l'endoderme
WO2015098963A1 (fr)	2013-12-26	2015-07-02	東亞合成株式会社	Procédé permettant de promouvoir l'expression de la calréticuline, et peptide synthétique pouvant être utilisé dans ledit procédé
WO2015199039A1 (fr)	2014-06-23	2015-12-30	東亞合成株式会社	Peptide permettant d'induire la multinucléation dans les cellules et utilisation associée
US10138469B2 (en)	2014-06-23	2018-11-27	Toagosei Co., Ltd.	Synthetic peptide and use thereof
KR101695792B1 (ko) *	2014-09-04	2017-01-12	디오셀 주식회사	신규 세포막 투과 펩티드 및 생리활성 물질 전달체로서의 그의 용도
WO2016175303A1 (fr)	2015-04-28	2016-11-03	東亞合成株式会社	Procédé de production de cellules du myocarde à l'aide d'un peptide synthétique
JP6872713B2 (ja)	2015-05-29	2021-05-19	東亞合成株式会社	腫瘍細胞の放射線感受性を増大させる合成ペプチド及びその利用
JP6691756B2 (ja)	2015-09-29	2020-05-13	東亞合成株式会社	合成ペプチドを用いた神経幹細胞の生産方法
JP7194928B2 (ja) *	2018-07-30	2022-12-23	東亞合成株式会社	抗腫瘍ペプチドおよびその利用
JP7333538B2 (ja) *	2018-10-09	2023-08-25	東亞合成株式会社	抗ウイルス性ペプチドおよびその利用
US11505589B2 (en)	2018-11-08	2022-11-22	Toagosei Co., Ltd	Antitumor peptide and use thereof
JP7345753B2 (ja) *	2018-11-08	2023-09-19	東亞合成株式会社	抗腫瘍ペプチドおよびその利用
JP7329173B2 (ja) *	2019-06-25	2023-08-18	東亞合成株式会社	抗腫瘍ペプチドおよびその利用
JP7498889B2 (ja)	2020-01-30	2024-06-13	東亞合成株式会社	Ｃｔｌａ４とｂ７タンパク質との結合を抑制するペプチドおよびその利用
JP7041853B1 (ja) *	2020-09-14	2022-03-25	東亞合成株式会社	キャリアペプチドフラグメントおよびその利用
CN119585295A (zh) *	2022-07-22	2025-03-07	东亚合成株式会社	载体肽片段及其利用
CN117304282B (zh) *	2023-10-23	2025-02-18	安徽大学	一种核仁定位信号肽及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004056854A1 (fr) *	2002-12-19	2004-07-08	Lg Life Sciences Ltd.	Transporteurs moleculaires pour administration intracellulaire et leurs applications
WO2007010989A1 (fr) *	2005-07-20	2007-01-25	Toagosei Co., Ltd.	Peptide induisant la différenciation neuronale et son utilisation

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Publication number	Priority date	Publication date	Assignee	Title
WO2001038547A2 (fr) *	1999-11-24	2001-05-31	Mcs Micro Carrier Systems Gmbh	Polypeptides comprenant des multimeres de signaux de localisation nucleaire ou de domaines de transduction de proteine et utilisations de ces derniers pour transferer des molecules dans des cellules
JP3854995B2 (ja)	2000-01-21	2006-12-06	関西ティー・エル・オー株式会社	細胞透過性キャリアペプチド
GB0103110D0 (en) *	2000-08-25	2001-03-28	Aventis Pharma Inc	A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1
JP2007145761A (ja) *	2005-11-28	2007-06-14	Tokyo Univ Of Pharmacy & Life Science	細胞膜透過性ペプチド修飾多糖−コレステロールまたは多糖−脂質非ウイルス性ベクターおよびその製造方法
JP2008014966A (ja)	2006-06-30	2008-01-24	Kyocera Mita Corp	定着装置及びその温度分布調節方法

2009
- 2009-01-23 US US12/864,147 patent/US20100297758A1/en not_active Abandoned
- 2009-01-23 JP JP2009550573A patent/JP4573143B2/ja active Active
- 2009-01-23 EP EP09704366A patent/EP2236514B1/fr active Active
- 2009-01-23 WO PCT/JP2009/051082 patent/WO2009093692A1/fr active Application Filing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004056854A1 (fr) *	2002-12-19	2004-07-08	Lg Life Sciences Ltd.	Transporteurs moleculaires pour administration intracellulaire et leurs applications
WO2007010989A1 (fr) *	2005-07-20	2007-01-25	Toagosei Co., Ltd.	Peptide induisant la différenciation neuronale et son utilisation

Non-Patent Citations (4)

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Title
CSERPAN I. ET AL.: "The mechanism of nuclear transport of natural or artificial transport substrates in digitonin-permeabilized cells", J. CELL. SCI., vol. 108, no. 5, 1995, pages 1849 - 1861, XP002622538 *
GOYAL PANKAJ ET AL: "Phosphorylation-dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 1 SEP 2006 LNKD- PUBMED:16820362, vol. 281, no. 35, 1 September 2006 (2006-09-01), pages 25223 - 25230, XP002622536, ISSN: 0021-9258 *
KOBAYASHI NAHOKO ET AL: "Nucleolar Localization Signals of LIM Kinase 2 Function as a Cell-Penetrating Peptide", PROTEIN AND PEPTIDE LETTERS, BENTHAM SCIENCE PUBLISHERS, NL, vol. 17, no. 12, 1 December 2010 (2010-12-01), pages 1480 - 1488, XP009144516, ISSN: 0929-8665 *
TAKEI Y. ET AL.: "Possible involvement of a pertussis toxin-sensitive GTP-binding protein in protein transport into nuclei isolated from rat liver", J. BIOCHEM., vol. 115, no. 3, 1994, pages 578 - 583, XP002622537 *

Also Published As

Publication number	Publication date
JPWO2009093692A1 (ja)	2011-05-26
US20100297758A1 (en)	2010-11-25
EP2236514A1 (fr)	2010-10-06
WO2009093692A1 (fr)	2009-07-30
JP4573143B2 (ja)	2010-11-04
EP2236514B1 (fr)	2013-04-03

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