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EP2185261A4 - Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics - Google Patents

Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics

Info

Publication number
EP2185261A4
EP2185261A4 EP08831194.9A EP08831194A EP2185261A4 EP 2185261 A4 EP2185261 A4 EP 2185261A4 EP 08831194 A EP08831194 A EP 08831194A EP 2185261 A4 EP2185261 A4 EP 2185261A4
Authority
EP
European Patent Office
Prior art keywords
apparatuses
methods
dna analysis
medical diagnostics
sorting objects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08831194.9A
Other languages
German (de)
French (fr)
Other versions
EP2185261A1 (en
Inventor
Tania Chakrabarty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arryx Inc
Original Assignee
Arryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arryx Inc filed Critical Arryx Inc
Publication of EP2185261A1 publication Critical patent/EP2185261A1/en
Publication of EP2185261A4 publication Critical patent/EP2185261A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/007—Devices specially adapted for forensic samples, e.g. tamper-proofing, sample tracking
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP08831194.9A 2007-09-13 2008-09-11 Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics Withdrawn EP2185261A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96005907P 2007-09-13 2007-09-13
PCT/US2008/010599 WO2009035621A1 (en) 2007-09-13 2008-09-11 Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics

Publications (2)

Publication Number Publication Date
EP2185261A1 EP2185261A1 (en) 2010-05-19
EP2185261A4 true EP2185261A4 (en) 2013-08-28

Family

ID=40452333

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08831194.9A Withdrawn EP2185261A4 (en) 2007-09-13 2008-09-11 Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics

Country Status (5)

Country Link
US (2) US7998676B2 (en)
EP (1) EP2185261A4 (en)
JP (1) JP2010538644A (en)
CN (1) CN101801491A (en)
WO (1) WO2009035621A1 (en)

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Publication number Priority date Publication date Assignee Title
US20110177547A1 (en) * 2004-12-10 2011-07-21 Arryx, Inc. Particle Sorting Using Fluid Streams
WO2010144814A2 (en) 2009-06-13 2010-12-16 Arryx, Inc. Particle sorting using fluid streams
US7381096B2 (en) * 2005-10-28 2008-06-03 Hewlett-Packard Development Company, L.P. Media power protection system and method
US8169600B2 (en) 2006-09-15 2012-05-01 Arryx, Inc. Surface mapping by optical manipulation of particles in relation to a functionalized surface
US8328368B2 (en) * 2007-04-26 2012-12-11 Accuvein Inc. Projection system
CN102482631A (en) * 2009-07-07 2012-05-30 索尼公司 Microfluidic device suitable for selective extraction of samples following centrifugation and methods of use thereof
US20110312651A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Microfluidic device with low mass probe spots
CN103124797B (en) * 2010-10-04 2015-04-22 霍夫曼-拉罗奇有限公司 Method for cell lysis and PCR in the same reaction vessel
SG11201504638RA (en) * 2012-12-12 2015-07-30 Hitachi Chemical Co Ltd Cancer cell isolation device and cancer cell isolation method
US11318479B2 (en) * 2013-12-18 2022-05-03 Berkeley Lights, Inc. Capturing specific nucleic acid materials from individual biological cells in a micro-fluidic device
US10415031B2 (en) 2015-02-04 2019-09-17 InnoGenomics Technologies, LLC Method, apparatus and kit for human identification using polymer filter means for separation of sperm cells from biological samples that include other cell types
US10030241B2 (en) 2015-03-30 2018-07-24 General Electric Company Methods and kits for capturing sperm nucleic acids
US9957548B2 (en) 2015-03-30 2018-05-01 General Electric Company Methods of capturing sperm nucleic acids
KR101906969B1 (en) 2017-09-15 2018-10-11 삼성전자주식회사 Gene analysis apparatus and method of analyzing gene using the same
CN109900624A (en) * 2019-04-04 2019-06-18 西安交通大学 A kind of unicellular separator and method based on micro-fluidic chip
CN110484434A (en) * 2019-08-09 2019-11-22 北方民族大学 Micro-fluidic chip, based on micro-fluidic cell sorting method and system
CN112300918A (en) * 2020-09-29 2021-02-02 北京航空航天大学 Microfluidic system, bacteria separation method, computer device and readable storage medium

Citations (2)

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US5436157A (en) * 1989-03-03 1995-07-25 The University Of Virginia Alumni Patents Foundation Human intra-acrosomal sperm antigen
WO1999039223A1 (en) * 1998-02-03 1999-08-05 Arch Development Corporation Apparatus for applying optical gradient forces

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US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
US7008771B1 (en) * 1994-09-30 2006-03-07 Promega Corporation Multiplex amplification of short tandem repeat loci
US6540895B1 (en) * 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
AU1778701A (en) * 1999-11-17 2001-05-30 University Of Virginia Patent Foundation Sperm cell selection system
CN1545561A (en) * 2001-06-20 2004-11-10 阿尔利克斯公司 Configurable dynamic three-dimensional array
ES2646622T3 (en) * 2002-07-31 2017-12-14 Premium Genetics (Uk) Limited System and method of classification of materials using holographic laser direction
US7118676B2 (en) * 2003-09-04 2006-10-10 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US6863406B2 (en) * 2002-08-01 2005-03-08 The University Of Chicago Apparatus and method for fabricating, sorting, and integrating materials with holographic optical traps
CN1230531C (en) * 2002-12-09 2005-12-07 清华大学 Method and kit for separating cell particle from sample
EP1594694A4 (en) * 2002-12-30 2010-01-20 Univ California METHODS AND APPARATUS FOR DETECTION AND ANALYSIS OF PATHOGENIC AGENTS
US7416892B2 (en) * 2003-01-21 2008-08-26 Micronics, Inc. Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing
CA2513535C (en) * 2003-01-29 2012-06-12 454 Corporation Bead emulsion nucleic acid amplification
US20050255606A1 (en) * 2004-05-13 2005-11-17 Biospect, Inc., A California Corporation Methods for accurate component intensity extraction from separations-mass spectrometry data
WO2005023391A2 (en) * 2003-07-31 2005-03-17 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US20060008823A1 (en) * 2004-05-12 2006-01-12 Kemp Jennifer T DNA profiling and SNP detection utilizing microarrays
WO2006001593A1 (en) * 2004-06-29 2006-01-05 Ti Square Technology Ltd. Method and apparatus for sending voice message in mobile network
US20060228758A1 (en) * 2004-09-13 2006-10-12 Xencor, Inc. Analysis of MHC-peptide binding interactions
JP2006217818A (en) * 2005-02-08 2006-08-24 Konica Minolta Medical & Graphic Inc Micro reactor for inspecting gene and method for inspecting gene
TW200632099A (en) * 2004-12-10 2006-09-16 Arryx Inc Automated extraction and purification of samples using optical tweezers
US20070077570A1 (en) * 2005-05-31 2007-04-05 Applera Corporation Multiplexed amplification of short nucleic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436157A (en) * 1989-03-03 1995-07-25 The University Of Virginia Alumni Patents Foundation Human intra-acrosomal sperm antigen
WO1999039223A1 (en) * 1998-02-03 1999-08-05 Arch Development Corporation Apparatus for applying optical gradient forces

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
S C GROVER ET AL: "Automated single-cell sorting system based on optical trapping", JOURNAL OF BIOMEDICAL OPTICS, 1 January 2001 (2001-01-01), pages 14 - 22, XP055057231, Retrieved from the Internet <URL:http://biomedicaloptics.spiedigitallibrary.org/article.aspx?articleid=1101359> [retrieved on 20130320], DOI: 10.1117/1.1333676] *
See also references of WO2009035621A1 *
STEVENSON R: "PCR and optical trapping may team up for single cell genetic screening", AMERICAN BIOTECHNOLOGY LABORATORY, SHELTON, CT, US, vol. 9, no. 9, 1 January 1991 (1991-01-01), pages 14, XP009168227, ISSN: 0749-3223 *

Also Published As

Publication number Publication date
WO2009035621A1 (en) 2009-03-19
CN101801491A (en) 2010-08-11
EP2185261A1 (en) 2010-05-19
US20110223653A1 (en) 2011-09-15
JP2010538644A (en) 2010-12-16
US20090075826A1 (en) 2009-03-19
US7998676B2 (en) 2011-08-16

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