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EP2170874A4 - Novel compounds and their use - Google Patents

Novel compounds and their use

Info

Publication number
EP2170874A4
EP2170874A4 EP08762934A EP08762934A EP2170874A4 EP 2170874 A4 EP2170874 A4 EP 2170874A4 EP 08762934 A EP08762934 A EP 08762934A EP 08762934 A EP08762934 A EP 08762934A EP 2170874 A4 EP2170874 A4 EP 2170874A4
Authority
EP
European Patent Office
Prior art keywords
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08762934A
Other languages
German (de)
French (fr)
Other versions
EP2170874A2 (en
Inventor
Simi Pushpan
Uma Ramachandran
Mrinalkanti Kundu
Veenaa Anantharaman
Santhosh Subramanian
Radhakrishnan Viswanathan
Ravikumar Tadiparthi
Maneesh Paul-Sathyaseela
Shakti Singh Solanki
Kesavan Koppolu
Sathishkumar Devarajan
Martin Gnanamuthu
Thanga Mariappan
Narayanan Surendran
Sriram Rajagopal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Research Laboratories Ltd
Original Assignee
Orchid Research Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Research Laboratories Ltd filed Critical Orchid Research Laboratories Ltd
Publication of EP2170874A2 publication Critical patent/EP2170874A2/en
Publication of EP2170874A4 publication Critical patent/EP2170874A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP08762934A 2007-06-22 2008-06-20 Novel compounds and their use Withdrawn EP2170874A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1294CH2007 2007-06-22
IN560CH2008 2008-03-05
PCT/IB2008/001620 WO2009001192A2 (en) 2007-06-22 2008-06-20 Novel compounds and their use

Publications (2)

Publication Number Publication Date
EP2170874A2 EP2170874A2 (en) 2010-04-07
EP2170874A4 true EP2170874A4 (en) 2011-08-31

Family

ID=40186093

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08762934A Withdrawn EP2170874A4 (en) 2007-06-22 2008-06-20 Novel compounds and their use

Country Status (3)

Country Link
EP (1) EP2170874A4 (en)
CA (1) CA2692255A1 (en)
WO (1) WO2009001192A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5662940B2 (en) 2008-11-20 2015-02-04 パナセア バイオテック リミテッド New antimicrobial agents
JP6162704B2 (en) * 2011-10-11 2017-07-12 カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ Sila analogs of oxazolidinone derivatives and their synthesis
US10995097B2 (en) 2016-03-11 2021-05-04 The Board Of Trustees Of The University Of Illinois Small molecules active against gram-negative bacteria
WO2018237140A1 (en) 2017-06-23 2018-12-27 The Board Of Trustees Of The University Of Illinois Topoisomerase inhibitors with antibacterial and antcancer activity
CN115466253B (en) * 2021-06-16 2024-08-20 沈阳药科大学 Oxazolidinone compound containing dithiocarbamic acid ester structure and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998054161A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
WO2001044212A1 (en) * 1999-12-14 2001-06-21 Pharmacia & Upjohn Company Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent
US20010041728A1 (en) * 1997-05-30 2001-11-15 Hester Jackson B. Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US20020137754A1 (en) * 2000-02-10 2002-09-26 Hester Jackson B. Oxazolidinone thioamides with piperazine amide substituents
WO2004045616A1 (en) * 2002-11-21 2004-06-03 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
US20050203102A1 (en) * 2004-03-09 2005-09-15 Orchid Chemicals & Pharmaceuticals Ltd. antibacterial agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000204084A (en) * 1998-11-11 2000-07-25 Hokuriku Seiyaku Co Ltd Thiocarbamic acid derivative
KR20010107987A (en) * 1998-11-27 2001-12-07 로렌스 티. 마이젠헬더 Oxazolidinone Antibacterial Agents Having a Thiocarbonyl Functionality
WO2001058885A1 (en) * 2000-02-10 2001-08-16 Pharmacia & Upjohn Company Oxazolidinone thioamides with piperazine amide substituents
EP1495021A2 (en) * 2002-04-01 2005-01-12 Cadila Healthcare Ltd. Antiinfectve compounds, process for their preparation and pharmaceutical compositions containing them
WO2005113520A1 (en) * 2004-05-20 2005-12-01 Pharmacia & Upjohn Company Llc Substituted 2,3,5-trifluorphenyl oxazolidinones for use as antibacterial agents

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998054161A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US20010041728A1 (en) * 1997-05-30 2001-11-15 Hester Jackson B. Oxazolidinone antibacterial agents having a thiocarbonyl functionality
WO2001044212A1 (en) * 1999-12-14 2001-06-21 Pharmacia & Upjohn Company Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent
US20020137754A1 (en) * 2000-02-10 2002-09-26 Hester Jackson B. Oxazolidinone thioamides with piperazine amide substituents
WO2004045616A1 (en) * 2002-11-21 2004-06-03 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
US20050203102A1 (en) * 2004-03-09 2005-09-15 Orchid Chemicals & Pharmaceuticals Ltd. antibacterial agents

Also Published As

Publication number Publication date
EP2170874A2 (en) 2010-04-07
WO2009001192A3 (en) 2010-05-27
CA2692255A1 (en) 2008-12-31
WO2009001192A2 (en) 2008-12-31

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Legal Events

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

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Extension state: AL BA MK RS

R17D Deferred search report published (corrected)

Effective date: 20100527

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 31/04 20060101ALI20100601BHEP

Ipc: A61K 31/497 20060101ALI20100601BHEP

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20110803

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 31/04 20060101ALI20110728BHEP

Ipc: A61K 31/497 20060101ALI20110728BHEP

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Ipc: C07D 413/10 20060101AFI20110728BHEP

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