EP2076281A4 - Stabilizing alkylglycoside compositions and methods thereof - Google Patents

Stabilizing alkylglycoside compositions and methods thereof

Info

Publication number: EP2076281A4
Authority: EP; European Patent Office
Prior art keywords: methods; stabilizing; alkylglycoside compositions; compositions; stabilizing alkylglycoside
Prior art date: 2006-06-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP06785482A

Other languages

German (de)

French (fr)

Other versions

EP2076281A1 (en

Inventor

Edward T Maggio

Michael R Ruff

Candace B Pert

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aegis Therapeutics LLC

Original Assignee

Aegis Therapeutics LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-23

Filing date

2006-06-23

Publication date

2010-03-03

2006-06-23 Application filed by Aegis Therapeutics LLC filed Critical Aegis Therapeutics LLC

2006-06-23 Priority to EP12165052.7A priority Critical patent/EP2505189B1/en

2006-06-23 Priority to EP09162179A priority patent/EP2158898A1/en

2006-06-23 Priority to EP09161107A priority patent/EP2158920A1/en

2009-07-08 Publication of EP2076281A1 publication Critical patent/EP2076281A1/en

2010-03-03 Publication of EP2076281A4 publication Critical patent/EP2076281A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Diabetes (AREA)
Microbiology (AREA)
Dermatology (AREA)
Virology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Otolaryngology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

EP06785482A 2006-06-23 2006-06-23 Stabilizing alkylglycoside compositions and methods thereof Withdrawn EP2076281A4 (en)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
EP12165052.7A EP2505189B1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof
EP09162179A EP2158898A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof
EP09161107A EP2158920A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and methods thereof

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2006/024577 WO2007149096A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and methods thereof

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
EP12165052.7A Division EP2505189B1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof
EP09161107.9 Division-Into		2009-05-26

Publications (2)

Publication Number	Publication Date
EP2076281A1 EP2076281A1 (en)	2009-07-08
EP2076281A4 true EP2076281A4 (en)	2010-03-03

Family

ID=38833712

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
EP09161107A Withdrawn EP2158920A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and methods thereof
EP06785482A Withdrawn EP2076281A4 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and methods thereof
EP12165052.7A Active EP2505189B1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof
EP09162179A Withdrawn EP2158898A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EP09161107A Withdrawn EP2158920A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and methods thereof

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
EP12165052.7A Active EP2505189B1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof
EP09162179A Withdrawn EP2158898A1 (en)	2006-06-23	2006-06-23	Stabilizing alkylglycoside compositions and method thereof

Country Status (3)

Country	Link
EP (4)	EP2158920A1 (en)
CA (2)	CA2714867A1 (en)
WO (1)	WO2007149096A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7598343B1 (en)	2008-07-27	2009-10-06	The Medicines Company	Pharmaceutical formulations of bivalirudin and processes of making the same
US7582727B1 (en)	2008-07-27	2009-09-01	The Medicinces Company	Pharmaceutical formulations of bivalirudin and processes of making the same
WO2011094632A1 (en) *	2010-01-29	2011-08-04	The Uab Research Foundation	Method for administration of insulin and pharmaceutical composition thereof
WO2011139838A2 (en) *	2010-04-28	2011-11-10	Zelos Therapeutics, Inc.	Intranasal formulations
CN103068367B (en) *	2010-06-24	2016-09-07	弗·哈夫曼-拉罗切有限公司	For stably containing the compositions containing alkyl polyglucoside and the method for the preparation of protein
GB201607918D0 (en)	2016-05-06	2016-06-22	Arecor Ltd	Novel formulations
AU2017334289B2 (en) *	2016-09-29	2023-04-20	Arecor Limited	Novel formulations
CN115015533B (en) *	2022-05-31	2024-06-25	江西英大生物技术有限公司	Oxidized low-density lipoprotein assay kit
CN117599193A (en) *	2023-11-24	2024-02-27	皓阳生物科技(上海)有限公司	Composition of matter comprising antigen and surfactant, and preparation method and application thereof

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3219656A (en)	1963-08-12	1965-11-23	Rohm & Haas	Alkylpolyalkoxyalkyl glucosides and process of preparation therefor
US3839318A (en)	1970-09-27	1974-10-01	Rohm & Haas	Process for preparation of alkyl glucosides and alkyl oligosaccharides
DK149776C (en)	1984-01-06	1987-04-21	Orion Yhtymae Oy	ANTIBIOTIC EFFECT OF ERYTHROMYCIN COMPOUND AND PREPARATION CONTAINING THE COMPOUND
AT382381B (en)	1984-10-02	1987-02-25	Oesterr Zuckerfab Evidenz	METHOD FOR PRODUCING NEW INTERFACE CHARACTERISTIC CARBOHYDRATE DERIVATIVES
US5427908A (en)	1990-05-01	1995-06-27	Affymax Technologies N.V.	Recombinant library screening methods
US5252318A (en)	1990-06-15	1993-10-12	Allergan, Inc.	Reversible gelation compositions and methods of use
GB9015198D0 (en)	1990-07-10	1990-08-29	Brien Caroline J O	Binding substance
US5661130A (en)	1993-06-24	1997-08-26	The Uab Research Foundation	Absorption enhancers for drug administration
EP1789075A4 (en) *	2004-08-25	2009-07-01	Uab Research Foundation	ABSORPTION ENHANCING SUBSTANCES FOR THE ADMINISTRATION OF MEDICINAL PRODUCTS

2006
- 2006-06-23 EP EP09161107A patent/EP2158920A1/en not_active Withdrawn
- 2006-06-23 EP EP06785482A patent/EP2076281A4/en not_active Withdrawn
- 2006-06-23 EP EP12165052.7A patent/EP2505189B1/en active Active
- 2006-06-23 CA CA2714867A patent/CA2714867A1/en not_active Abandoned
- 2006-06-23 EP EP09162179A patent/EP2158898A1/en not_active Withdrawn
- 2006-06-23 WO PCT/US2006/024577 patent/WO2007149096A1/en active Application Filing
- 2006-06-23 CA CA2743725A patent/CA2743725A1/en not_active Abandoned

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ROCCATANO DANILO ET AL: "Mechanism by which 2,2,2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: a molecular dynamics study.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 17 SEP 2002, vol. 99, no. 19, 17 September 2002 (2002-09-17), pages 12179 - 12184, XP002563234, ISSN: 0027-8424 *

Also Published As

Publication number	Publication date
EP2505189B1 (en)	2018-08-08
EP2076281A1 (en)	2009-07-08
CA2714867A1 (en)	2007-12-27
CA2743725A1 (en)	2007-12-27
EP2505189A1 (en)	2012-10-03
EP2158898A1 (en)	2010-03-03
EP2158920A1 (en)	2010-03-03
WO2007149096A1 (en)	2007-12-27

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Legal Events

Date	Code	Title	Description
2009-06-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2009-07-08	17P	Request for examination filed	Effective date: 20090120
2009-07-08	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
2009-07-08	AX	Request for extension of the european patent	Extension state: AL BA HR MK RS
2009-11-25	DAX	Request for extension of the european patent (deleted)
2010-02-24	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 38/28 20060101ALI20100120BHEP Ipc: A61K 47/26 20060101ALI20100120BHEP Ipc: A61K 38/29 20060101ALI20100120BHEP Ipc: A61K 38/27 20060101ALI20100120BHEP Ipc: A61K 38/21 20060101ALI20100120BHEP Ipc: A61K 38/18 20060101ALI20100120BHEP Ipc: A61K 38/08 20060101ALI20100120BHEP Ipc: A61K 9/19 20060101AFI20100120BHEP
2010-03-03	A4	Supplementary search report drawn up and despatched	Effective date: 20100129
2010-05-12	17Q	First examination report despatched	Effective date: 20100413
2013-09-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2013-10-23	18D	Application deemed to be withdrawn	Effective date: 20130507