[go: up one dir, main page]

EP2035093A4 - Methods of treating spinal cord injury and minimizing scarring - Google Patents

Methods of treating spinal cord injury and minimizing scarring

Info

Publication number
EP2035093A4
EP2035093A4 EP07777388A EP07777388A EP2035093A4 EP 2035093 A4 EP2035093 A4 EP 2035093A4 EP 07777388 A EP07777388 A EP 07777388A EP 07777388 A EP07777388 A EP 07777388A EP 2035093 A4 EP2035093 A4 EP 2035093A4
Authority
EP
European Patent Office
Prior art keywords
methods
spinal cord
cord injury
treating spinal
minimizing scarring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07777388A
Other languages
German (de)
French (fr)
Other versions
EP2035093A1 (en
Inventor
Vivienne S Marshall
Diana L Clarke
George L Sing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stemnion LLC
Original Assignee
Stemnion LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemnion LLC filed Critical Stemnion LLC
Publication of EP2035093A1 publication Critical patent/EP2035093A1/en
Publication of EP2035093A4 publication Critical patent/EP2035093A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP07777388A 2006-06-14 2007-06-04 Methods of treating spinal cord injury and minimizing scarring Withdrawn EP2035093A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81375906P 2006-06-14 2006-06-14
PCT/US2007/013140 WO2007145889A1 (en) 2006-06-14 2007-06-04 Methods of treating spinal cord injury and minimizing scarring

Publications (2)

Publication Number Publication Date
EP2035093A1 EP2035093A1 (en) 2009-03-18
EP2035093A4 true EP2035093A4 (en) 2010-02-17

Family

ID=38832059

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07777388A Withdrawn EP2035093A4 (en) 2006-06-14 2007-06-04 Methods of treating spinal cord injury and minimizing scarring

Country Status (2)

Country Link
EP (1) EP2035093A4 (en)
WO (1) WO2007145889A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101815531B (en) * 2007-08-22 2015-01-14 斯丹姆涅恩有限公司 Novel compositions containing cytokine solutions
MX2013006592A (en) * 2010-12-17 2014-02-06 Anthrogenesis Corp Treatment of spinal cord injury and traumatic brain injury using amnion derived adherent cells.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105152A2 (en) * 2005-03-31 2006-10-05 Stemnion, Inc. Amnion-derived cell compositions, methods of making and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002046373A1 (en) 2000-12-06 2002-06-13 Hariri Robert J Method of collecting placental stem cells
IL157350A0 (en) 2001-02-14 2004-02-19 Anthrogenesis Corp Post-partum mammalian placenta, its use and placental stem cells therefrom
WO2003042405A2 (en) 2001-11-15 2003-05-22 Children's Medical Center Corporation Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof
US20040161419A1 (en) 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
EP1497435A4 (en) 2002-04-19 2005-07-27 Univ Pittsburgh STEM CELLS DERIVED FROM PLAZENTA AND THEIR USES
US20040110287A1 (en) 2002-07-29 2004-06-10 Es Cell International Pte Ltd. Multi-step method for the differentiation of insulin positive, glucose responsive cells
CA2530421C (en) * 2003-06-27 2015-04-21 Ethicon, Incorporated Repair and regeneration of ocular tissue using postpartum-derived cells
US20050152995A1 (en) * 2003-06-27 2005-07-14 Chen Dong F. Methods and compositions for promoting axon regeneration and cell replacement therapy
DK1789534T3 (en) 2004-08-16 2014-11-17 Cellres Corp Pte Ltd ISOLATION OF stem / progenitor cells FOSTER HINDE FROM an umbilical cord
US20060222634A1 (en) 2005-03-31 2006-10-05 Clarke Diana L Amnion-derived cell compositions, methods of making and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105152A2 (en) * 2005-03-31 2006-10-05 Stemnion, Inc. Amnion-derived cell compositions, methods of making and uses thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DE CASTRO M ET AL: "Evaluation of human serum albumin as a substitute of foetal bovine serum for cell culture", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 310, no. 1-2, 9 March 2006 (2006-03-09), pages 8 - 14, XP025113345, ISSN: 0378-5173, [retrieved on 20060309], DOI: 10.1016/J.IJPHARM.2005.10.028 *
NORIO SAKURAGAWA ET AL: "Evidence for active acetylcholine metabolism in human amniotic epithelial cells: applicable to intracerebral allografting for neurologic disease", NEUROSCIENCE LETTERS, vol. 232, no. 1, 1 August 1997 (1997-08-01), pages 53 - 56, XP055062974, ISSN: 0304-3940, DOI: 10.1016/S0304-3940(97)00570-3 *
SAKURAGAWA N ET AL: "EXPRESSION OF MARKERS FOR BOTH NEURONAL AND GLIAL CELLS IN HUMAN AMNIOTIC EPITHELIAL CELLS", NEUROSCIENCE LETTERS, LIMERICK, IE, vol. 209, 1 January 1996 (1996-01-01), pages 9 - 12, XP000983495, ISSN: 0304-3940, DOI: 10.1016/0304-3940(96)12599-4 *
SANKAR V ET AL: "Role of human amniotic epithelial cell transplantation in spinal cord injury repair research.", NEUROSCIENCE, vol. 118, no. 1, 25 April 2003 (2003-04-25), pages 11 - 17, XP002562017, ISSN: 0306-4522 *
See also references of WO2007145889A1 *
UCHIDA S ET AL: "NEUROTROPHIC FUNCTION OF CONDITIONED MEDIUM FROM HUMAN AMNIOTIC EPITHELIAL CELLS", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 62, no. 4, 15 November 2000 (2000-11-15), pages 585 - 590, XP001029688, ISSN: 0360-4012 *
WU ZHI-YUAN ET AL: "Transplantation of human amniotic epithelial cells improves hindlimb function in rats with spinal cord injury.", CHINESE MEDICAL JOURNAL 20 DEC 2006, vol. 119, no. 24, 20 December 2006 (2006-12-20), pages 2101 - 2107, XP002562018, ISSN: 0366-6999 *

Also Published As

Publication number Publication date
WO2007145889A1 (en) 2007-12-21
EP2035093A1 (en) 2009-03-18

Similar Documents

Publication Publication Date Title
EP2007284A4 (en) Devices and methods for treatment of tissue
IL194820A0 (en) Devices and methods for treatment of tissue
HK1150958A1 (en) Devices and methods for treating spinal cord tissue
EP1981463A4 (en) Shock wave treatment device and method of use
GB0624584D0 (en) Skin treatment apparatus and method
EP2081638A4 (en) Apparatus and methods for minimally invasive obesity treatment
HK1148232A1 (en) Mucosal tissue dressing and method of use
IL201602A0 (en) Adaptive surgical tourniquet apparatus and method
IL198663A0 (en) Tissue treatment methods
IL187444A0 (en) Tissue treatment device and method
EP2303193A4 (en) Devices and methods for treatment of facet and other joints
EP2037812A4 (en) Methods and apparatus for treatment of atrial fibrillation
EP1901694A4 (en) Method and apparatus for the treatment of tissue
GB0705617D0 (en) Bone treatment apparatus and method
EP2083876A4 (en) Methods of wound care and treatment
IL230911A0 (en) Apparatus for treating cardiac tissue and use thereof
EP2129313A4 (en) Surgical devices and methods of use thereof
EP1928337A4 (en) Methods and apparatuses for treatment of hollow organs
EP2303160A4 (en) Bone fracture treatment devices and methods of their use
IL198723A0 (en) Methods and compositions for therapeutic treatment
EP1906976A4 (en) Therapeutic polymers and methods of use
EP2023823A4 (en) Vertebral treatment device , system and methods of use
ZA200900489B (en) Apparatus and methods for skin treatment
EP1909052A4 (en) Method and device for drying treatment of cord
GB2445651B (en) Well treatment products and methods of using them

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20081223

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

A4 Supplementary search report drawn up and despatched

Effective date: 20100118

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 35/50 20060101ALI20100108BHEP

Ipc: A61P 25/00 20060101AFI20080228BHEP

17Q First examination report despatched

Effective date: 20110609

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 5/073 20100101AFI20130515BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20130726

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20131206