[go: up one dir, main page]

EP1888106A4 - COMPOSITIONS AND METHODS FOR TREATING EPHRIN SIGNALING WITH CUPREDOXINES - Google Patents

COMPOSITIONS AND METHODS FOR TREATING EPHRIN SIGNALING WITH CUPREDOXINES

Info

Publication number
EP1888106A4
EP1888106A4 EP06813192A EP06813192A EP1888106A4 EP 1888106 A4 EP1888106 A4 EP 1888106A4 EP 06813192 A EP06813192 A EP 06813192A EP 06813192 A EP06813192 A EP 06813192A EP 1888106 A4 EP1888106 A4 EP 1888106A4
Authority
EP
European Patent Office
Prior art keywords
cupredoxines
compositions
treating
methods
ephrin signaling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06813192A
Other languages
German (de)
French (fr)
Other versions
EP1888106A2 (en
Inventor
Ananda Chakrabarty
Gupta Tapas Das
Tohru Yamada
Anita Chaudhari
Arsenio Fialho
Yonghua Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois at Urbana Champaign
University of Illinois System
Original Assignee
University of Illinois at Urbana Champaign
University of Illinois System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/244,105 external-priority patent/US7691383B2/en
Application filed by University of Illinois at Urbana Champaign, University of Illinois System filed Critical University of Illinois at Urbana Champaign
Publication of EP1888106A2 publication Critical patent/EP1888106A2/en
Publication of EP1888106A4 publication Critical patent/EP1888106A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP06813192A 2005-05-20 2006-05-19 COMPOSITIONS AND METHODS FOR TREATING EPHRIN SIGNALING WITH CUPREDOXINES Withdrawn EP1888106A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68281205P 2005-05-20 2005-05-20
US11/244,105 US7691383B2 (en) 2004-10-07 2005-10-06 Cupredoxin derived transport agents and methods of use thereof
US76474906P 2006-02-03 2006-02-03
PCT/US2006/019684 WO2007018671A2 (en) 2005-05-20 2006-05-19 Compositions and methods for treating conditions related to ephrin signaling with cupredoxins

Publications (2)

Publication Number Publication Date
EP1888106A2 EP1888106A2 (en) 2008-02-20
EP1888106A4 true EP1888106A4 (en) 2009-01-14

Family

ID=37727776

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06813192A Withdrawn EP1888106A4 (en) 2005-05-20 2006-05-19 COMPOSITIONS AND METHODS FOR TREATING EPHRIN SIGNALING WITH CUPREDOXINES

Country Status (10)

Country Link
EP (1) EP1888106A4 (en)
JP (1) JP2008539795A (en)
KR (1) KR20080040631A (en)
AU (1) AU2006277009A1 (en)
BR (1) BRPI0612424A2 (en)
CA (1) CA2608512A1 (en)
IL (1) IL187138A0 (en)
MX (1) MX2007014598A (en)
NO (1) NO20076391L (en)
WO (1) WO2007018671A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9096663B2 (en) 2001-02-15 2015-08-04 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof
US7556810B2 (en) 2005-07-19 2009-07-07 The Board Of Trustees Of The University Of Ilinois Compositions and methods to control angiogenesis with cupredoxins
US7381701B2 (en) 2001-02-15 2008-06-03 The Borad Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins
CN101437842A (en) 2004-10-07 2009-05-20 阿南达·查克拉博蒂 Cupredoxin derived transport formulations and methods of use thereof
MX2008000993A (en) * 2005-07-19 2008-03-19 Univ Illinois Compositions and methods to control angiogenesis with cupredoxins.
EP1904642A4 (en) 2005-07-19 2008-11-26 Univ Illinois TRANSPORT AGENTS USEFUL FOR CROSSING THE HEMATO-ENCEPHALIC BARRIER AND FOR PENETRATING IN CANCER CELLS OF THE BRAIN, METHODS OF USING THE SAME
WO2008033987A2 (en) * 2006-09-14 2008-03-20 The Board Of Trustees Of The University Of Illinois Compositions and methods to prevent cancer with cupredoxins
WO2008086523A2 (en) * 2007-01-11 2008-07-17 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof
RU2525133C2 (en) 2007-08-30 2014-08-10 Дайити Санкио Компани, Лимитед Antibody to epha2
KR101102829B1 (en) * 2008-09-12 2012-01-05 재단법인 제주테크노파크 Perilla extract and its use as anti-inflammatory
CN110090295B (en) * 2018-01-29 2022-12-23 武汉康理通科技有限公司 Application of Ephrin-B1 in preparation of medicine for treating inflammatory bowel disease
EP4511052A2 (en) * 2022-04-22 2025-02-26 University of Miami Ephrin ligand mimetic peptides for the treatment of neurodegenerative diseases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076380A2 (en) * 2001-02-15 2002-10-03 The Board Of Trustees Of The University Of Illinois Cytotoxic factors for modulating cell death
WO2005018662A1 (en) * 2003-08-15 2005-03-03 Board Of Trustees Of The University Of Illinois Use of polypeptides of the cupredoxin family in cancer therapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076380A2 (en) * 2001-02-15 2002-10-03 The Board Of Trustees Of The University Of Illinois Cytotoxic factors for modulating cell death
US20060040269A1 (en) * 2001-02-15 2006-02-23 Chakrabarty Ananda M Cytotoxic factors for modulating cell death
WO2005018662A1 (en) * 2003-08-15 2005-03-03 Board Of Trustees Of The University Of Illinois Use of polypeptides of the cupredoxin family in cancer therapy

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HIMANEN J-P ET AL: "Eph signaling: a structural view", TRENDS IN NEUROSCIENCE, ELSEVIER, AMSTERDAM, NL, vol. 26, no. 1, 1 January 2003 (2003-01-01), pages 46 - 51, XP004398871, ISSN: 0166-2236 *
TOTH JOSEPH ET AL: "Crystal structure of an ephrin ectodomain", DEVELOPMENTAL CELL, vol. 1, no. 1, July 2001 (2001-07-01), pages 83 - 92, XP002505155, ISSN: 1534-5807 *
YAMADA TOHRU ET AL: "Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, no. 22, 29 October 2002 (2002-10-29), pages 14098 - 14103, XP002486971, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2007018671A3 (en) 2007-11-22
KR20080040631A (en) 2008-05-08
CA2608512A1 (en) 2007-02-15
EP1888106A2 (en) 2008-02-20
WO2007018671A2 (en) 2007-02-15
MX2007014598A (en) 2008-02-07
NO20076391L (en) 2008-02-15
IL187138A0 (en) 2008-02-09
AU2006277009A1 (en) 2007-02-15
JP2008539795A (en) 2008-11-20
BRPI0612424A2 (en) 2009-01-27

Similar Documents

Publication Publication Date Title
EP1888106A4 (en) COMPOSITIONS AND METHODS FOR TREATING EPHRIN SIGNALING WITH CUPREDOXINES
ATE489955T1 (en) METHOD AND COMPOSITION FOR TREATING PERIPHERAL VASCULAR DISEASES
EP1855649A4 (en) METHOD FOR THE TREATMENT OF ATHEROSCLEROSIS, HYPERLIPIDIA AND RELATED DISEASES
EP1812031A4 (en) COMPOSITIONS AND METHOD FOR MODIFYING BIOMOLECULES
EP1948675A4 (en) METHOD AND COMPOSITIONS FOR TREATING MARFAN SYNDROME AND RELATED DISEASES
EP1881823A4 (en) COMPOSITIONS AND METHOD FOR THE TREATMENT OF EYE DISEASES
DE602007006479D1 (en) METHOD AND DEVICES FOR TREATING SEVERAL DRILLING INTERVALS
ATE518423T1 (en) COMPOSITION AND METHOD FOR IMPROVING PLANT HEALTH
EP1907013A4 (en) COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CHEMOSTOROUS NEOPLASIA
ATE500824T1 (en) METHOD FOR PURIFYING TRANS-(-)-DELTA9-TETRAHYDROCANNABINOL AND TRANS-(+)-DELTA9-TETRAHYDROCANNABINOL
DE602006019753D1 (en) METHOD AND APPARATUS FOR THE TREATMENT OF ANEURYSMS OF A. THORACICA
EP2370593A4 (en) METHOD FOR THE TREATMENT OF INFECTIONS AND TUMORS
DE602005008970D1 (en) METHOD AND COMPOSITIONS FOR TREATING EYE DISEASES WITH RETINYL DERIVATIVES
DE602006021318D1 (en) INSECTICIDE COMPOSITIONS AND METHODS FOR HERSE
EP2326375A4 (en) DEVICES AND METHOD FOR MINIMIZING AND TREATING HEIGHT-RELATED APPLICATIONS
EP1948178A4 (en) PROCESS FOR TREATING PREVIOUS LAYOMS WITH P38 INHIBITOR COMPOUNDS
DE602006003973D1 (en) Method and device for water treatment
DE602006004529D1 (en) Method and device for controlling objects
DE602006015182D1 (en) COMPOSITION AND METHOD FOR CONTROLLING INSECTS
DE602006004968D1 (en) METHOD AND APPENDIX FOR THE CONVERSION OF CHROMIUM-DANGEROUS WASTE INTO UNFOLLOWED WASTE
EP1948690A4 (en) COMPOSITIONS AND METHODS OF HEMOSTASE MODULATION
EP2049140A4 (en) KIT AND METHOD FOR TREATING THE BELTS
EP1848834A4 (en) METHOD FOR TREATING COPPER-CONTAINING MATERIALS
ATE540755T1 (en) USE OF CATALYST COMPOSITIONS AND METHODS FOR OXYCHLORIATION
EP1934025A4 (en) COMPOSITION FOR THE TREATMENT OF WOOD, METHOD FOR THE TREATMENT OF WOOD AND WOOD PRODUCT

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20071123

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK YU

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ZHU, YONGHUA

Inventor name: FIALHO, ARSENIO

Inventor name: CHAUDHARI, ANITA

Inventor name: YAMADA, TOHRU

Inventor name: DAS GUPTA, TAPAS

Inventor name: CHAKRABARTY, ANANDA

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20081202BHEP

Ipc: A61P 31/18 20060101ALI20081202BHEP

Ipc: A61K 38/16 20060101ALI20081202BHEP

Ipc: C07K 14/21 20060101ALI20081202BHEP

Ipc: C07K 14/195 20060101AFI20081202BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20081211

17Q First examination report despatched

Effective date: 20090326

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20121006