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EP1872765B1 - Personalized blister pack and method for automated packaging of an individually determined composition - Google Patents

Personalized blister pack and method for automated packaging of an individually determined composition Download PDF

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Publication number
EP1872765B1
EP1872765B1 EP20060116277 EP06116277A EP1872765B1 EP 1872765 B1 EP1872765 B1 EP 1872765B1 EP 20060116277 EP20060116277 EP 20060116277 EP 06116277 A EP06116277 A EP 06116277A EP 1872765 B1 EP1872765 B1 EP 1872765B1
Authority
EP
European Patent Office
Prior art keywords
blister pack
usage
memory device
personalized
pack according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP20060116277
Other languages
German (de)
French (fr)
Other versions
EP1872765A1 (en
Inventor
Edwin Kohl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to PL06116277T priority Critical patent/PL1872765T3/en
Application filed by Individual filed Critical Individual
Priority to DE200650003608 priority patent/DE502006003608D1/en
Priority to AT06116277T priority patent/ATE429893T1/en
Priority to EP20060116277 priority patent/EP1872765B1/en
Priority to DK06116277T priority patent/DK1872765T3/en
Priority to ES06116277T priority patent/ES2326333T3/en
Priority to JP2009517203A priority patent/JP2009540989A/en
Priority to ES07786876T priority patent/ES2440486T3/en
Priority to EP20070786876 priority patent/EP2032113B1/en
Priority to US12/306,781 priority patent/US20090277815A1/en
Priority to PCT/EP2007/056469 priority patent/WO2008000790A1/en
Publication of EP1872765A1 publication Critical patent/EP1872765A1/en
Priority to HK08103565A priority patent/HK1109329A1/en
Application granted granted Critical
Publication of EP1872765B1 publication Critical patent/EP1872765B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0454—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers for dispensing of multiple drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0463—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers for multiple patients

Definitions

  • the invention relates to a blister pack for the automated packaging of an individually defined product combination, in particular consisting of medicaments for a specific person and for a fixed period of time, for example a week, and an associated packaging method.
  • a blister pack for the weekly drug needs of a patient known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) order.
  • the receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form with seven daily lines, each with at least three time of day compartments, which are covered in total by a continuous blister foil.
  • Affixed to the blister pack is a carton-shaped lid, on which the patient-individual the composition of the individual time-of-day subjects as well as prescribing information concerning the respective medicaments is contained.
  • Such packaging units are for patients who need to take several different medications regularly, a help not only to remember the intake of important drugs and on the other hand to keep a reliable overview of what medications are already taken to u. U. to avoid harmful over-medication.
  • the printed instructions for taking in the described weekly blister pack may be difficult to read due to the large number of necessary information, especially for older patients due to the limited font for reasons of space font. In addition, there is a risk that the patient misses the time for the application of a drug.
  • the WO 2004/002396 A1 describes a blister pack for medicines for use in particular in clinical tests comprising a memory device for storing application data of the drugs contained in the blister pack, a memory device and a circuit arrangement for detecting an electrical resistance, if a blister compartment is opened and thus a drug was removed.
  • the US 2004/01721630 A1 describes a device for packaging medicaments that are packaged in circular cans with a plurality of drug compartments, wherein circuitry is provided on which medicament application data is stored to remind the patient of the ingestion.
  • a personalized blister pack for the automated packaging of an individually defined product combination, in particular medicaments, according to claim 1.
  • the storage device makes it possible to individually store the application data such as the product itself, the dose, application times, etc., for the respective person, so that the data can be made accessible by audible or visual output.
  • the memory device enables the output of an application reminder signal reminding the patient to take certain medications or other preparations at a particular time.
  • the reminder signal may be an acoustic or an optical or even a vibration alarm signal.
  • Signal parameters such as the volume of an acoustic signal may be adjustable, for example.
  • an acknowledgment function can be provided, either by the patient actively confirming the product application by pressing a button or the like, or by providing a sensor for each receptacle of the blister pack that detects a tearing of the film of the corresponding compartment.
  • the memory element may, for example, be an EPROM memory element or else an RFID or a flash memory element.
  • the memory element may be formed as write-once memory for single use of the memory element or as rewritable memory for multiple use of the memory device.
  • the storage device may preferably include an interface for receiving updated application data for the patient, for example via a mobile radio network, wireless LAN, Bluetooth or the like.
  • the personal identification data associated with the particular person may be stored in the memory device, wherein the latter may have an output device for outputting the personal identification data.
  • the blister pack may further be provided with an identifier assigned to the particular person, for example as a barcode or the like.
  • the storage means is removably attached to the blister pack and includes a support means such as a fastening tape or the like on.
  • the storage device preferably has a waterproof, washable and shockproof housing.
  • the blister pack according to the invention is suitable for packaging a wide variety of products such as medicines, vitamin preparations, nutritional supplements and the like, wherein the storage device can store the application data for the products contained in the blister pack, but also other products.
  • a further object of the present invention is to propose a method for automatically packaging a product combination determined in each case individually, in particular consisting of medicaments, for a large number of persons for a certain period of time (eg one week) and simultaneously for a need-based one Reliable support for the application of the delivered products.
  • the object is achieved by a method according to claim 28.
  • the person or the patient is provided with the application data of the products contained in the packaging unit and, if appropriate, further products to be used in order to support a demand-oriented application on the storage device.
  • the reminder function reminds the patient of a timely medication.
  • the reminder can be done by acoustic signal, optical signal or the like.
  • the storage device can be removably attached to the packaging unit (in particular blister pack), and be designed either for single or multiple use. With repeated use, the application data can be updated wirelessly, for example via the mobile network, wireless LAN or a Bluetooth interface.
  • FIG. 1 shows a schematic perspective view of an embodiment of a weekly blister according to the invention with storage unit.
  • FIG. 2 is a block diagram of an embodiment of the memory unit according to the invention.
  • FIG. 3 is a schematic representation for explaining an embodiment of the method according to the invention.
  • FIG. 4 is a flowchart for explaining the method steps of the method according to the invention.
  • FIG. 1 shows an embodiment of a personalized blister pack according to the invention 20.
  • This is designed as a so-called weekly blister for supplying a person or a patient with medicines and similar products such as vitamin supplements, dietary supplements, etc. for a period of one week.
  • the invention is not limited to a specific period of time.
  • a detachable by a perforation line of 24 in the example shown four receiving compartments 22 are provided, each of the applied products for "early”, “noon”, “evening” or “at night” or for breakfast, lunch, dinner and bedtime.
  • a different number of storage compartments 22 may be provided, for example, three storage compartments for each meal before, during or after the particular meal.
  • the - in the in FIG. 1 shown embodiment - a total of 28 storage compartments 22 are made of a preferably transparent thermoplastic material inexpensively in mass production by deep drawing and have enough space for a plurality of tablets, capsules, dragees, etc. All receiving compartments 22 can by a common film 25, for example.
  • a thin Aluminum foil be closed and be provided with symbols for the collection time (morning, noon, evening, night). By tearing the thin foil, the patient can comfortably remove the products to be taken at the time of day.
  • the personalized blister pack 20 may be provided with an identifier 29 associated with the respective patient, for example as a barcode is trained. Other types of personal identifiers are also possible.
  • the blister pack as in the WO 2005/102862 described one have hinged lid.
  • the blister pack 20 is still as in FIG. 1 illustrated with a memory device 50, in which the application data of the storage compartments and possibly other products such as dietary supplements, ointments, etc. are stored.
  • the storage device 50 can be designed as a single-use memory for single use for the period of use of the blister pack (for example, a week) or as multiple times writable memory that is returned to the pharmacy after the week for further use or by remote data transmission for will be updated next week.
  • the storage device 50 may be removably attached to the blister pack 20 with adhesives, hook-and-loop fastener, fastener tape, or the like so that the patient can easily detach them from the blister pack without damaging the blister sheet 25.
  • the storage device may have a carrying device such as the illustrated fastening strap 60, so that the patient can, for example, hang the storage device around his neck or otherwise carry him with him.
  • the memory device has a memory element 52, which as mentioned may be a write once or a rewritable memory.
  • a memory element 52 which as mentioned may be a write once or a rewritable memory.
  • EPROM or flash memory device may be used, and other memory technologies - such as those known from smart cards - may also be used.
  • the memory device 50 has an interface unit 54, which allows a description of the memory with the product application data.
  • the interface 54 may also be designed to update the data stored in the memory element 52, for example by infrared, Bluetooth, wireless LAN or a mobile network.
  • the memory device 50 comprises a timer 56 and an output unit 58 in order to realize a reminder function for the patient.
  • the timer 56 supplies Signal to the Ausgeabe worn 58, which then emits a warning signal.
  • the output device 58 is a miniaturized loudspeaker that emits a beep, or better, a synthesized speech signal with specific application notes, such as "take a red tablet before lunch,” or "take heart remedies for dinner.”
  • the volume can be adjustable by means of a (not shown) control device.
  • an optical output device may be used, which outputs the application notes on a small display.
  • the most comfortable reminder function for the patient should be possible with the help of speech synthesis.
  • personal identification data associated with the respective patient are stored in addition to the application data.
  • the output device 58 can output these for the user / patient for checking.
  • the memory device 50 may be designed to be inexpensive and space and weight-saving, such as a SIM card of a mobile phone.
  • a (in FIG. 2 not shown) power supply unit such as a small battery or a capacitor may be provided.
  • the Memory element 50 can also be designed as a passive element in accordance with an RFID chip and receive radio frequency signals via the interface unit 54 provided with a radio frequency antenna and also use these for power supply.
  • the storage device is provided with a waterproof, washable and impact-resistant, yet inexpensive housing, for example. Made of plastic.
  • the reminder signal possibly disturbing
  • a key or the like for a certain period of time, such as 10 minutes.
  • Such functionality is known, for example, with alarm clocks.
  • the suppressed signal can then be output later with a time delay to later remind the patient of the (possibly missed) product application.
  • a sensor device may be provided for this purpose, which detects a tearing of the corresponding film section for each of the receiving compartments 22 and thus closes on the prescription-related medication application.
  • the individual prescription data ie the medicaments and other products prescribed to the patient (vitamin preparations, Dietary supplements, ointments, etc.) is preferably detected in the respective patient care pharmacy and stored in the subsequent step S2 in a database 80.
  • the database 80 may be as in FIG. 3 outlines a decentralized, maintained in the pharmacy or even act around a central database.
  • a packaging machine or equipping machine 90 equipped to supply a large number (possibly several hundreds of thousands) of patients is supplied with medicines in large quantities by manufacturers.
  • the application data of patients from the database 80 and each patient in the subsequent process step S4 an individual blister 20 in which the medicines prescribed for that patient for the period are packaged.
  • step S5 Based on the read application data, in a further method step S5, these application data are also stored on a memory device 50 assigned to the respective patient, and the memory device is then attached to the packaging unit 20 in step S6.
  • the method steps S5 and S6 can also be performed in reverse order of time.
  • step S7 the correspondence of the personal identification data stored in the storage device with the identifier 29 attached to the packaging unit is checked.
  • a verification of the correctness of the assignment of packaging unit 20 with the stored in the memory device 50 application data can be done so that the patient in any case its associated products and application data are delivered.
  • the blister packs (eg weekly blister) produced in such a fast, safe and reasonably priced manner are delivered to the respective pharmacies, who then provide the weekly blisters provided with the storage element to the respective patient.
  • the storage device 50 can also contain application data of products that are not delivered with the blister, for example, ointments, medicinal teas, bath treatments or the like.
  • the application data on the storage device is preferably updated wirelessly, for example by means of a special mobile radio signal or also a Bluetooth or infrared interface provided in the pharmacy.
  • the invention thus enables the fast, safe and inexpensive supply of a large number of patients with the individually prescribed product or drug composition.
  • the convenient handling of the blister pack and the memory device provided with a reminder function supports a need-based medication of the patient, so that he is more able to provide himself and is not dependent on inpatient care.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Basic Packing Technique (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Packages (AREA)

Abstract

The pack (20) has a receiving compartment (22) closed by a foil for a product composition. The receiving compartment is arranged in a matrix form with lines for an application stage and an opening for application times during daytime. A storage device (50) stores application data of the product composition of a certain person for a fixed period of one week, where the storage device is designed as a flash-storage unit. An output device produces an application-reminder signal for a reminder at the specified product application time based on the stored application data. An independent claim is also included for a method for automated packing of an individually specified product composition e.g. medicine.

Description

Gebiet der ErfindungField of the invention

Die Erfindung betrifft eine Blisterpackung für die automatisierte Verpackung einer individuell festgelegten Produktzusammenstellung, insbesondere bestehend aus Medikamenten für eine bestimmte Person und für einen festgelegten Zeitraum, bspw. eine Woche, sowie ein zugehöriges Verpackungsverfahren.The invention relates to a blister pack for the automated packaging of an individually defined product combination, in particular consisting of medicaments for a specific person and for a fixed period of time, for example a week, and an associated packaging method.

Verwandter Stand der TechnikRelated prior art

Aus der WO 2005/102862 A1 ist eine Blisterpackung für den wöchentlichen Medikamentenbedarf eines Patienten bekannt, der die Medikamente in einer nach Datum, Wochentag und Tageszeit (Morgen, Mittag und Abend und/oder Nacht) geordneten Folge einnehmen soll. Die Aufnahmefächer der Blisterpackung zur Aufnahme der jeweiligen Medikamente sind in Matrixform angeordnet mit sieben Tages-Zeilen mit jeweils mindestens drei Tageszeit-Fächern, die insgesamt durch eine zusammenhängende Blisterfolie abgedeckt sind. An der Blisterpackung angebracht ist ein kartonförmiger Deckel, auf dem patientenindividuell die Zusammensetzung der einzelnen Tageszeit-Fächer sowie Verschreibungsinformation betreffend die jeweiligen Medikamente enthalten ist.From the WO 2005/102862 A1 is a blister pack for the weekly drug needs of a patient known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) order. The receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form with seven daily lines, each with at least three time of day compartments, which are covered in total by a continuous blister foil. Affixed to the blister pack is a carton-shaped lid, on which the patient-individual the composition of the individual time-of-day subjects as well as prescribing information concerning the respective medicaments is contained.

Derartige Verpackungseinheiten sind für Patienten, die regelmäßig mehrere verschiedene Medikamente einnehmen müssen, eine Hilfe dafür, einerseits das Einnehmen wichtiger Medikamente nicht zu vergessen und andererseits auch einen zuverlässigen Überblick darüber zu behalten, welche Medikamente schon eingenommen sind, um eine u. U. schädliche Übermedikation zu vermeiden.Such packaging units are for patients who need to take several different medications regularly, a help not only to remember the intake of important drugs and on the other hand to keep a reliable overview of what medications are already taken to u. U. to avoid harmful over-medication.

Der in der WO 2005/102862 A1 beschriebene Wochenblister unterstützt so zuverlässig eine bedarfsgerechte Medikation der Patienten und ist gleichzeitig preisgünstig herstellbar und mittels einer Bestückungsmaschine für eine große Zahl von Patienten individuell bestückbar.The Indian WO 2005/102862 A1 Wochenblister described so reliably supports a needs-based medication of the patient and is also inexpensive to manufacture and individually equipped by means of a placement machine for a large number of patients.

Die bedruckten Einnahmehinweise bei der beschriebenen Wochenblisterpackung sind jedoch aufgrund der Vielzahl der notwendigen Angaben insbesondere für ältere Patienten aufgrund der aus Platzgründen limitierten Schrift ggf. schwierig zu lesen. Außerdem besteht die Gefahr, dass der Patient den Zeitpunkt für die Anwendung eines Medikaments versäumt.The printed instructions for taking in the described weekly blister pack, however, may be difficult to read due to the large number of necessary information, especially for older patients due to the limited font for reasons of space font. In addition, there is a risk that the patient misses the time for the application of a drug.

Die WO 2004/002396 A1 beschreibt eine Blisterpackung für Medikamente für den Einsatz insbesondere bei klinischen Tests aufweisend eine Speichereinrichtung zur Speicherung von Anwendungsdaten der in der Blisterpackung befindlichen Medikamente, eine Erinnerungseinrichtung und eine Schaltungsanordnung zur Erfassung anhand eines elektrischen Widerstandes, ob ein Blisterfach geöffnet und somit ein Medikament entnommen wurde.The WO 2004/002396 A1 describes a blister pack for medicines for use in particular in clinical tests comprising a memory device for storing application data of the drugs contained in the blister pack, a memory device and a circuit arrangement for detecting an electrical resistance, if a blister compartment is opened and thus a drug was removed.

Die US 2004/01721630 A1 beschreibt eine Vorrichtung zur Verpackung von Medikamenten, die in kreisförmige Dosen mit einer Vielzahl von Medikamentenfächern verpackt werden, wobei eine Schaltungseinrichtung vorgesehen ist, auf der Medikamenten-Anwendungsdaten zur Erinnerung des Patienten an die Einnahme gespeichert werden.The US 2004/01721630 A1 describes a device for packaging medicaments that are packaged in circular cans with a plurality of drug compartments, wherein circuitry is provided on which medicament application data is stored to remind the patient of the ingestion.

Zusammenfassung der ErfindungSummary of the invention

Es ist daher eine Aufgabe der Erfindung, die bekannte personalisierte Blisterpackung so weiterzuentwickeln dass sie eine bessere Unterstützung bei der bedarfsgerechten Medikation des Patienten bietet.It is therefore an object of the invention to further develop the known personalized blister pack so as to provide better support in the patient's on-demand medication.

Gelöst wird die Aufgabe durch eine personalisierte Blisterpackung für die automatisierte Verpackung einer individuell festgelegten Produktzusammenstellung, insbesondere Medikamente, gemäß Anspruch 1.The object is achieved by a personalized blister pack for the automated packaging of an individually defined product combination, in particular medicaments, according to claim 1.

Die Speichereinrichtung ermöglicht es, die Anwendungsdaten wie etwa das Produkt selbst, die Dosis, Anwendungszeiten usw. für die jeweilige Person individuell abzuspeichern, so dass die Daten durch akustische oder optische Ausgabe zugänglich gemacht werden können. Insbesondere ermöglicht die Speichereinrichtung die Ausgabe eines Anwendungs-Erinnerungssignals, das den Patienten daran erinnert, bestimmte Medikamente oder andere Präparate zu einem bestimmten Zeitpunkt einzunehmen. Das Erinnerungssignal kann dabei ein akustisches oder ein optisches oder auch ein Vibrationsalarmsignal sein. Signalparameter wie etwa die Lautstärke eines akustischen Signals können beispielsweise einstellbar sein. Vorzugsweise ist es auch möglich, das Erinnerungssignal für eine bestimmte Zeitspanne zu unterdrücken, wobei das unterdrückte Signal vorzugsweise zeitversetzt ausgebbar ist. Weiterhin kann eine Quittierungsfunktion vorgesehen sein, entweder dadurch, dass der Patient die Produktanwendung aktiv durch einen Tastendruck oder dergleichen bestätigt oder dass ein Sensor für jedes Aufnahmefach der Blisterpackung vorgesehen ist, der ein Aufreißen der Folie des entsprechenden Faches erfasst.The storage device makes it possible to individually store the application data such as the product itself, the dose, application times, etc., for the respective person, so that the data can be made accessible by audible or visual output. In particular, the memory device enables the output of an application reminder signal reminding the patient to take certain medications or other preparations at a particular time. The reminder signal may be an acoustic or an optical or even a vibration alarm signal. Signal parameters such as the volume of an acoustic signal may be adjustable, for example. Preferably, it is also possible to suppress the reminder signal for a certain period of time, wherein the suppressed signal is preferably outputting time-offset. Furthermore, an acknowledgment function can be provided, either by the patient actively confirming the product application by pressing a button or the like, or by providing a sensor for each receptacle of the blister pack that detects a tearing of the film of the corresponding compartment.

Bei dem Speicherelement kann es sich bspw. um ein EPROM-Speicherelement oder auch um ein RFID- oder ein Flash-Speicherelement handeln. Das Speicherelement kann als einmal beschreibbarer Speicher zur einmaligen Verwendung des Speicherelements oder auch als mehrfach beschreibbarer Speicher zur mehrfachen Verwendung der Speichereinrichtung ausgebildet sein. Vorzugsweise kann die Speichereinrichtung eine Schnittstelle zum Empfang aktualisierter Anwendungsdaten für den Patienten bspw. über ein Mobilfunknetz, Wireless LAN, Bluetooth oder dergleichen enthalten.The memory element may, for example, be an EPROM memory element or else an RFID or a flash memory element. The memory element may be formed as write-once memory for single use of the memory element or as rewritable memory for multiple use of the memory device. The storage device may preferably include an interface for receiving updated application data for the patient, for example via a mobile radio network, wireless LAN, Bluetooth or the like.

In der Speichereinrichtung können der bestimmten Person zugeordnete Personenidentifikationsdaten abgespeichert sein, wobei diese eine Ausgabeeinrichtung zur Ausgabe der Personenidentifikationsdaten aufweisen kann.The personal identification data associated with the particular person may be stored in the memory device, wherein the latter may have an output device for outputting the personal identification data.

Die Blisterpackung kann weiterhin mit einer der bestimmten Person zugeordneten beispielsweise als Barcode oder dgl. augebildeten Kennung versehen sein.The blister pack may further be provided with an identifier assigned to the particular person, for example as a barcode or the like.

Vorzugsweise ist die Speichereinrichtung entfernbar an der Blisterpackung angebracht und weist eine Trageinrichtung wie etwa ein Befestigungsband oder dergleichen auf. Die Speichereinrichtung weist dabei vorzugsweise ein wasserfestes, abwaschbares und stoßfestes Gehäuse auf.Preferably, the storage means is removably attached to the blister pack and includes a support means such as a fastening tape or the like on. The storage device preferably has a waterproof, washable and shockproof housing.

Die erfindungsgemäße Blisterpackung ist geeignet zur Verpackung von verschiedensten Produkten wie Medikamenten, Vitaminpräparaten, Nahrungsergänzungsmitteln und dergleichen, wobei die Speichereinrichtung die Anwendungsdaten für die in der Blisterpackung enthaltenen, aber auch weitere Produkte speichern kann.The blister pack according to the invention is suitable for packaging a wide variety of products such as medicines, vitamin preparations, nutritional supplements and the like, wherein the storage device can store the application data for the products contained in the blister pack, but also other products.

Der vorliegenden Erfindung liegt weiterhin die Aufgabe zugrunde, ein Verfahren vorzuschlagen, eine jeweils individuell bestimmte Produktzusammenstellung, insbesondere bestehend aus Medikamenten, für eine Vielzahl von Personen für einen bestimmten Zeitraum (bspw. eine Woche) automatisiert zu verpacken und die jeweiligen Personen gleichzeitig bei einer bedarfsgerechten Anwendung der gelieferten Produkte zuverlässig zu unterstützen.A further object of the present invention is to propose a method for automatically packaging a product combination determined in each case individually, in particular consisting of medicaments, for a large number of persons for a certain period of time (eg one week) and simultaneously for a need-based one Reliable support for the application of the delivered products.

Gelöst wird die Aufgabe durch ein Verfahren gemäß Anspruch 28.The object is achieved by a method according to claim 28.

Durch das erfindungsgemäße Verfahren werden der Person bzw. dem Patienten die Anwendungsdaten der in der Verpackungseinheit befindlichen Produkte sowie ggf. weiterer, anzuwendender Produkte zur Unterstützung einer bedarfsgerechten Anwendung auf der Speichereinrichtung zur Verfügung gestellt. Durch die Erinnerungsfunktion wird der Patient an eine rechtzeitige Medikamenteneinnahme erinnert.By means of the method according to the invention, the person or the patient is provided with the application data of the products contained in the packaging unit and, if appropriate, further products to be used in order to support a demand-oriented application on the storage device. The reminder function reminds the patient of a timely medication.

Die Erinnerung kann per akustischem Signal, optischem Signal oder dergleichen erfolgen.The reminder can be done by acoustic signal, optical signal or the like.

Die Speichereinrichtung kann abnehmbar an der Verpackungseinheit (insbesondere Blisterpackung), angebracht sein und dabei entweder zur einmaligen oder mehrmaligen Verwendung ausgebildet sein. Bei mehrmaliger Verwendung können die Anwendungsdaten drahtlos aktualisiert werden, bspw. über das Mobilfunknetz, Wireless LAN oder eine Bluetooth-Schnittstelle.The storage device can be removably attached to the packaging unit (in particular blister pack), and be designed either for single or multiple use. With repeated use, the application data can be updated wirelessly, for example via the mobile network, wireless LAN or a Bluetooth interface.

Durch den Verfahrensschritt der Überprüfung der Übereinstimmung von in der Speichereinrichtung abgespeicherten Personenidentifikationsdaten mit einer an der Verpackungseinheit angebrachten Kennung kann eine Verifikation der Richtigkeit der Zuordnung von Verpackungseinheit und abgespeicherten Anwendungsdaten erfolgen und so die Sicherheit des Verfahrens erhöht werden.By the method step of checking the correspondence of personal identification data stored in the storage device with an identifier attached to the packaging unit, verification of the correctness of the assignment of packaging unit and stored application data can take place and thus the security of the method can be increased.

Kurze Beschreibung der ZeichnungenBrief description of the drawings

Die Erfindung wird im folgenden anhand von Ausführungsbeispielen unter Bezugnahme auf die Zeichnungen im Detail beschrieben.The invention will be described below in detail with reference to embodiments with reference to the drawings.

Figur 1 zeigt eine schematische Perspektivansicht eines Ausführungsbeispiels eines erfindungsgemäßen Wochenblisters mit Speichereinheit. FIG. 1 shows a schematic perspective view of an embodiment of a weekly blister according to the invention with storage unit.

Figur 2 ist ein Blockschaltbild eines Ausführungsbeispiels der erfindungsgemäßen Speichereinheit. FIG. 2 is a block diagram of an embodiment of the memory unit according to the invention.

Figur 3 ist eine schematische Darstellung zur Erläuterung eines Ausführungsbeispiels des erfindungsgemäßen Verfahrens. FIG. 3 is a schematic representation for explaining an embodiment of the method according to the invention.

Figur 4 ist ein Flussdiagramm zur Erläuterung der Verfahrensschritte des erfindungsgemäßen Verfahrens. FIG. 4 is a flowchart for explaining the method steps of the method according to the invention.

Detaillierte Beschreibung der ErfindungDetailed description of the invention

Figur 1 zeigt ein Ausführungsbeispiel einer erfindungsgemäßen personalisierten Blisterpackung 20. Diese ist als sogenannter Wochenblister ausgebildet zur Versorgung einer Person bzw. eines Patienten mit Medikamenten und ähnlichen Produkten wie etwa Vitaminpräparaten, Nahrungsergänzungsmitteln etc. für den Zeitraum von einer Woche. Selbstverständlich ist die Erfindung nicht auf einen bestimmten Zeitraum beschränkt. Für jeden Tag der Woche ist bei der insgesamt matrixförmigen Blisterpackung 20 eine durch eine Perforation 24 abtrennbare Zeile von in dem gezeigten Beispiel vier Aufnahmefächern 22 vorgesehen, die jeweils die anzuwendenden Produkte für "früh", "mittags", "abends" oder "nachts" bzw. für "zum Frühstück", "zum Mittagessen", "zum Abendessen" und "vor dem Schlafengehen" enthalten. Je nach Anwendungsgebiet kann auch eine andere Zahl von Aufnahmefächern 22 vorgesehen sein, bspw. für jede Mahlzeit drei Aufnahmefächer entsprechend vor, während oder nach der jeweiligen Mahlzeit. FIG. 1 shows an embodiment of a personalized blister pack according to the invention 20. This is designed as a so-called weekly blister for supplying a person or a patient with medicines and similar products such as vitamin supplements, dietary supplements, etc. for a period of one week. Of course, the invention is not limited to a specific period of time. For each day of the week in the total matrix-shaped blister pack 20 a detachable by a perforation line of 24 in the example shown four receiving compartments 22 are provided, each of the applied products for "early", "noon", "evening" or "at night" or for breakfast, lunch, dinner and bedtime. Depending on the field of application, a different number of storage compartments 22 may be provided, for example, three storage compartments for each meal before, during or after the particular meal.

Die - in dem in Figur 1 gezeigten Ausführungsbeispiel - insgesamt 28 Aufnahmefächer 22 sind aus einem vorzugsweise durchsichtigen thermoplastischen Material preiswert in Massenanfertigung durch Tiefziehen hergestellt und haben genügend Platz für jeweils eine Mehrzahl von Tabletten, Kapseln, Dragees etc. Alle Aufnahmefächer 22 können durch eine gemeinsame Folie 25, bspw. eine dünne Aluminiumfolie, verschlossen sein und mit Symbolen für die Entnahmezeit (morgens, mittags, abend, nachts) versehen sein. Der Patient kann durch Aufreißen der dünnen Folie bequem die zur jeweiligen Tageszeit einzunehmenden Produkte entnehmen.The - in the in FIG. 1 shown embodiment - a total of 28 storage compartments 22 are made of a preferably transparent thermoplastic material inexpensively in mass production by deep drawing and have enough space for a plurality of tablets, capsules, dragees, etc. All receiving compartments 22 can by a common film 25, for example. A thin Aluminum foil, be closed and be provided with symbols for the collection time (morning, noon, evening, night). By tearing the thin foil, the patient can comfortably remove the products to be taken at the time of day.

Durch die Perforation 24 sowohl der die Aufnahmefächer 22 bildenden Kunststoffplatine als auch der Folie 25 können von der Blisterpackung 20 Tagesstreifen zur bequemen Mitnahme abgetrennt werden.Through the perforation 24 of both the receiving compartments 22 forming plastic plate and the film 25 can be separated from the blister pack 20 day strips for convenient driving.

Die personalisierte Blisterpackung 20 kann mit einer dem jeweiligen Patienten zugeordneten Kennung 29 versehen sein, die beispielsweise als Barcode ausgebildet ist. Andere Typen von Personenkennungen sind jedoch ebenfalls möglich.The personalized blister pack 20 may be provided with an identifier 29 associated with the respective patient, for example as a barcode is trained. Other types of personal identifiers are also possible.

Zum Schutz der Blisterpackung und ggf. zum Aufdrucken von Verschreibungsinformation kann die Blisterpackung wie in der WO 2005/102862 beschrieben einen (in Figur 1 nicht dargestellten) klappbaren Deckel aufweisen. Die Blisterpackung 20 ist weiterhin wie in Figur 1 dargestellt mit einer Speichereinrichtung 50 versehen, in der die Anwendungsdaten der in den Aufnahmefächern befindlichen sowie ggf. weiterer Produkte wie Nahrungsergänzungsmittel, Salben etc. gespeichert sind. Die Speichereinrichtung 50 kann dabei als einmal beschreibbarer Speicher zur einmaligen Verwendung für den Nutzungszeitraum der Blisterpackung (bspw. eine Woche) oder auch als mehrmals beschreibbarer Speicher ausgebildet sein, der nach Ablauf der Woche wieder zur weiteren Verwendung an die Apotheke zurückgegeben wird oder per Datenfernübertragung für die nächste Woche aktualisiert wird.To protect the blister pack and possibly for printing prescription information, the blister pack as in the WO 2005/102862 described one (in FIG. 1 not shown) have hinged lid. The blister pack 20 is still as in FIG FIG. 1 illustrated with a memory device 50, in which the application data of the storage compartments and possibly other products such as dietary supplements, ointments, etc. are stored. The storage device 50 can be designed as a single-use memory for single use for the period of use of the blister pack (for example, a week) or as multiple times writable memory that is returned to the pharmacy after the week for further use or by remote data transmission for will be updated next week.

Die Speichereinrichtung 50 kann mit Klebemitteln, Klettverschluss, einem Befestigungsband oder dergleichen entfernbar an der Blisterpackung 20 angebracht sein, so dass der Patient diese leicht von der Blisterpackung lösen kann, ohne die Blisterfolie 25 zu beschädigen. Die Speichereinrichtung kann eine Trageinrichtung wie das dargestellte Befestigungsband 60 aufweisen, so dass der Patient sich die Speichereinrichtung bspw. um den Hals hängen oder auf andere Weise mit sich befördern kann.The storage device 50 may be removably attached to the blister pack 20 with adhesives, hook-and-loop fastener, fastener tape, or the like so that the patient can easily detach them from the blister pack without damaging the blister sheet 25. The storage device may have a carrying device such as the illustrated fastening strap 60, so that the patient can, for example, hang the storage device around his neck or otherwise carry him with him.

Die wesentlichen Elemente eines Ausführungsbeispiels der erfindungsgemäßen Speichereinrichtung 50 werden nun unter Bezugnahme auf das Blockschaltbild von Figur 2 erläutert. Die Speichereinrichtung weist ein Speicherelement 52 auf, wobei es sich wie erwähnt um einen einmal beschreibbaren oder einen mehrfach beschreibbaren Speicher handeln kann. Beispielsweise kann ein EPROM- oder Flash-Speicherelement verwendet werden, wobei andere Speichertechnologien - wie sie etwa aus Chipkarten bekannt sind - ebenso einsetzbar sind.The essential elements of an embodiment of the memory device 50 according to the invention will now be described with reference to the block diagram of FIG FIG. 2 explained. The memory device has a memory element 52, which as mentioned may be a write once or a rewritable memory. For example, an EPROM or flash memory device may be used, and other memory technologies - such as those known from smart cards - may also be used.

Des Weiteren weist die Speichereinrichtung 50 eine Schnittstelleneinheit 54 auf, die ein Beschreiben des Speichers mit den Produkt-Anwendungsdaten erlaubt. Die Schnittstelle 54 kann außerdem ausgebildet sein zur Aktualisierung der im Speicherelement 52 gespeicherten Daten, bspw. per Infrarot, Bluetooth, Wireless LAN oder ein Mobilfunknetz.Furthermore, the memory device 50 has an interface unit 54, which allows a description of the memory with the product application data. The interface 54 may also be designed to update the data stored in the memory element 52, for example by infrared, Bluetooth, wireless LAN or a mobile network.

Weiterhin umfasst die Speichereinrichtung 50 einen Timer 56 sowie eine Ausgabeeinheit 58, um eine Erinnerungsfunktion für den Patienten zu realisieren. Basierend auf den im Speicherelement 52 gespeicherten Anwendungsdaten des Patienten, die den Einnahmezeitraum der jeweiligen Medikamente (morgens, mittags, abends, nachts) ggf. in Bezug auf die jeweiligen Mahlzeiten (vor, während oder nach der Mahlzeit) enthält, liefert die Zeitsteuereinrichtung 56 ein Signal an die Ausgeabeeinrichtung 58, die daraufhin ein Warnsignal abgibt. Im gezeigten Beispiel handelt es sich bei der Ausgabeeinrichtung 58 um einen miniaturisierten Lautsprecher, der einen Piepton oder besser ein synthetisiertes Sprachsignal mit genauen Anwendungshinweisen wie etwa "vor dem Mittagessen rote Tablette nehmen" oder etwa "zum Abendessen Herzmittel einnehmen" ausgibt. Die Lautstärke kann dabei mittels einer (nicht dargestellten) Regeleinrichtung einstellbar sein. Alternativ kann natürlich auch eine optische Ausgabeeinrichtung verwendet werden, die die Anwendungshinweise auf einer kleinen Anzeige ausgibt. Die für den Patienten komfortabelste Erinnerungsfunktion dürfte jedoch mit Hilfe der Sprachsynthetisierung realisierbar sein.Furthermore, the memory device 50 comprises a timer 56 and an output unit 58 in order to realize a reminder function for the patient. Based on the application data of the patient stored in the memory element 52, which contains the intake period of the respective medication (morning, noon, evening, night), possibly with respect to the respective meals (before, during or after the meal), the timer 56 supplies Signal to the Ausgeabeeinrichtung 58, which then emits a warning signal. In the example shown, the output device 58 is a miniaturized loudspeaker that emits a beep, or better, a synthesized speech signal with specific application notes, such as "take a red tablet before lunch," or "take heart remedies for dinner." The volume can be adjustable by means of a (not shown) control device. Alternatively, of course, an optical output device may be used, which outputs the application notes on a small display. However, the most comfortable reminder function for the patient should be possible with the help of speech synthesis.

In der Speichereinrichtung sind zusätzlich zu den Anwendungsdaten dem jeweiligen Patienten zugeordnete Personenidentifikationsdaten abgespeichert. Durch die Ausgabeeinrichtung 58 können diese für den Benutzer/Patienten zur Überprüfung ausgegeben werden.In the memory device, personal identification data associated with the respective patient are stored in addition to the application data. The output device 58 can output these for the user / patient for checking.

Die Speichereinrichtung 50 kann wie beispielsweise eine SIM-Karte eines Mobiltelefons preisgünstig sowie platz- und gewichtssparend ausgebildet sein. Zur Stromversorgung kann eine (in Figur 2 nicht dargestellte) Stromversorgungseinheit wie etwa eine kleine Batterie oder ein Kondensator vorgesehen sein. Das Speicherelement 50 kann jedoch auch als passives Element entsprechend einem RFID-Chip ausgebildet sein und über die mit einer Radiofrequenzantenne versehene Schnittstelleneinheit 54 Radiofrequenzsignale empfangen und diese auch zur Stromversorgung nutzen.The memory device 50 may be designed to be inexpensive and space and weight-saving, such as a SIM card of a mobile phone. For power supply, a (in FIG. 2 not shown) power supply unit such as a small battery or a capacitor may be provided. The Memory element 50, however, can also be designed as a passive element in accordance with an RFID chip and receive radio frequency signals via the interface unit 54 provided with a radio frequency antenna and also use these for power supply.

Zur sicheren Handhabung ist die Speichereinrichtung mit einem wasserfesten, abwaschbaren und stoßfesten, gleichwohl preiswerten Gehäuse bspw. aus Kunststoff versehen.For safe handling, the storage device is provided with a waterproof, washable and impact-resistant, yet inexpensive housing, for example. Made of plastic.

Vorzugsweise kann zusätzlich die Möglichkeit vorgesehen sein, das (möglicherweise störende) Erinnerungssignal durch Tastendruck oder dergleichen für eine bestimmte Zeitspanne wie etwa 10 Minuten zu unterdrücken. Eine derartige Funktionalität ist bspw. bei Weckern bekannt. Das unterdrückte Signal kann dann später zeitversetzt ausgegeben werden, um den Patienten nachträglich an die (möglicherweise versäumte) Produktanwendung zu erinnern.In addition, it may be possible to additionally suppress the reminder signal (possibly disturbing) by pressing a key or the like for a certain period of time, such as 10 minutes. Such functionality is known, for example, with alarm clocks. The suppressed signal can then be output later with a time delay to later remind the patient of the (possibly missed) product application.

Zur Überprüfung der verschreibungsgerechten Medikamentenanwendung (compliance) kann weiterhin eine (nicht dargestellte) Quittierungstaste vorgesehen sein, durch welche der Patient die verschreibungsgemäße Medikamentenanwendung quittiert. Alternativ kann zu diesem Zweck auch eine Sensoreinrichtung vorgesehen sein, die für jedes der Aufnahmefächer 22 ein Einreißen des entsprechenden Folienabschnitts erfasst und so auf die verschreibungsgemäße Medikamentenanwendung schließt.In order to check the prescription-compliant drug application (compliance), it is furthermore possible to provide an acknowledgment key (not shown), by means of which the patient acknowledges the prescription of the medication. Alternatively, a sensor device may be provided for this purpose, which detects a tearing of the corresponding film section for each of the receiving compartments 22 and thus closes on the prescription-related medication application.

Unter Bezugnahme auf die Figuren 3 und 4 wird im folgenden ein Ausführungsbeispiel des erfindungsgemäßen Verfahrens zur automatisierten Verpackung einer jeweils individuell bestimmten Produktzusammmenstellung für eine Vielzahl von Patienten in individuellen Verpackungseinheiten erläutert.With reference to the Figures 3 and 4 In the following, an exemplary embodiment of the method according to the invention for the automated packaging of a respectively individually determined product composition for a plurality of patients in individual packaging units will be explained.

Von einer Vielzahl von Patienten 100 werden in einem ersten Verfahrensschritt S1 zunächst die individuellen Verschreibungsdaten, d.h. die dem Patienten zur Anwendung verschriebenen Medikamente und anderen Produkte (Vitaminpräparate, Nahrungsergänzungsmittel, Salben etc.) vorzugsweise in der den jeweiligen Patienten betreuenden Apotheke erfasst und im nachfolgenden Verfahrensschritt S2 in einer Datenbank 80 abgespeichert. Bei der Datenbank 80 kann es sich wie in Figur 3 skizziert um eine dezentrale, in der Apotheke gepflegte oder auch um eine zentrale Datenbank handeln.Of a plurality of patients 100, in a first procedural step S1, the individual prescription data, ie the medicaments and other products prescribed to the patient (vitamin preparations, Dietary supplements, ointments, etc.) is preferably detected in the respective patient care pharmacy and stored in the subsequent step S2 in a database 80. The database 80 may be as in FIG. 3 outlines a decentralized, maintained in the pharmacy or even act around a central database.

Eine zur Versorgung einer großen Zahl (ggf. mehrere huderttausend) Patienten ausgerüstete Verpackungsmaschine oder Bestückungsmaschine 90 wird von Herstellern in großen Mengen mit Medikamenten versorgt. Zur personalisierten, patientenindividuellen Verpackung der einem Patienten jeweils verschriebenen Medikamente und/oder anderen Produkte in den vorher beschriebenen Blisterverpackungen für einen vorgegebenen Zeitraum werden im Verfahrensschritt S3 die Anwendungsdaten der Patienten aus der Datenbank 80 ausgelesen und jedem Patienten in dem darauffolgenden Verfahrensschritt S4 eine individuelle Blisterpackung 20 zugeordnet, in der die diesem Patienten für den Zeitraum verschriebenen Medikamente verpackt werden.A packaging machine or equipping machine 90 equipped to supply a large number (possibly several hundreds of thousands) of patients is supplied with medicines in large quantities by manufacturers. For personalized, patient-specific packaging of a patient's prescribed medication and / or other products in the previously described blister packs for a predetermined period in step S3, the application data of patients from the database 80 and each patient in the subsequent process step S4 an individual blister 20 in which the medicines prescribed for that patient for the period are packaged.

Basierend auf den ausgelesenen Anwendungsdaten werden im weiteren Verfahrensschritt S5 diese Anwendungsdaten außerdem auf einer dem jeweiligen Patienten zugeordneten Speichereinrichtung 50 abgespeichert und die Speichereinrichtung in Schritt S6 dann an der Verpackungseinheit 20 angebracht. Selbstverständlich können die Verfahrensschritte S5 und S6 auch in zeitlich umgekehrter Reihenfolge durchgeführt werden.Based on the read application data, in a further method step S5, these application data are also stored on a memory device 50 assigned to the respective patient, and the memory device is then attached to the packaging unit 20 in step S6. Of course, the method steps S5 and S6 can also be performed in reverse order of time.

Im weiteren Verfahrensschritt S7 wird die Übereinstimmung der in der Speichereinrichtung abgespeicherten Personenidentifikationsdaten mit der an der Verpackungseinheit angebrachten Kennung 29 überprüft. So kann eine Verifikation der Richtigkeit der Zuordnung von Verpackungseinheit 20 mit den in der Speichereinrichtung 50 abgespeicherten Anwendungsdaten erfolgen, so dass dem Patienten auf jeden Fall die ihm zugeordneten Produkte und Anwendungsdaten geliefert werden.In the further method step S7, the correspondence of the personal identification data stored in the storage device with the identifier 29 attached to the packaging unit is checked. Thus, a verification of the correctness of the assignment of packaging unit 20 with the stored in the memory device 50 application data can be done so that the patient in any case its associated products and application data are delivered.

Die so schnell, sicher und preisgünstig hergestellten Blisterpackungen (bspw. Wochenblister) werden an die jeweiligen Apotheken geliefert, die die mit Speicherelement versehenen Wochenblister dann den jeweiligen Patienten zur Verfügung stellen. Die Speichereinrichtung 50 kann dabei auch Anwendungsdaten von Produkten enthalten, die nicht mit dem Blister ausgeliefert werden, bspw. Salben, medizinische Tees, Bäderanwendungen oder dergleichen. Gemäß einer Variante der Erfindung kann wie erwähnt außerdem vorgesehen sein, dass die Anwendungsdaten auf der Speichereinrichtung vorzugsweise drahtlos aktualisiert werden, bspw. durch ein spezielles Mobilfunksignal oder auch eine in der Apotheke bereitgestellte Bluetooth- oder Infrarot-Schnittstelle.The blister packs (eg weekly blister) produced in such a fast, safe and reasonably priced manner are delivered to the respective pharmacies, who then provide the weekly blisters provided with the storage element to the respective patient. The storage device 50 can also contain application data of products that are not delivered with the blister, for example, ointments, medicinal teas, bath treatments or the like. According to a variant of the invention, as mentioned, it may also be provided that the application data on the storage device is preferably updated wirelessly, for example by means of a special mobile radio signal or also a Bluetooth or infrared interface provided in the pharmacy.

Die Erfindung ermöglicht so die schnelle, sichere und preiswerte Versorgung einer großen Anzahl von Patienten mit der individuell verschriebenen Produkt- bzw. Medikamentenzusammenstellung. Die bequeme Handhabung der Blisterpackung sowie die mitgelieferte Speichereinrichtung mit Erinnerungsfunktion unterstützt eine bedarfsgerechte Medikation des Patienten, so dass dieser länger in der Lage ist, sich selbst zu versorgen und nicht auf stationäre Pflege angewiesen ist.The invention thus enables the fast, safe and inexpensive supply of a large number of patients with the individually prescribed product or drug composition. The convenient handling of the blister pack and the memory device provided with a reminder function supports a need-based medication of the patient, so that he is more able to provide himself and is not dependent on inpatient care.

Claims (42)

  1. Personalized blister pack (20) for automated packaging of an individually defined product combination, particularly drugs, for a defined person, for a defined time period, having:
    - a plurality of receiving compartments (22), each closed by a foil (25), for the products of the product combination, said receiving compartments (22) each being associated with a defined usage time within the defined time period and disposed in matrix form, with a number of rows for usage days and columns for usage times during the day, and
    - a memory device (50) for storing the usage data of the products of the product combination of the defined person for the defined period, and which includes a device (58) for generating a usage reminder signal as a reminder of a defined product usage time based on the stored usage data, and characterized by
    - perforation sections (24), which make it possible to separate single rows of the blister pack, which is in the form of a matrix.
  2. Personalized blister pack according to Claim 1, wherein the product combination includes products like drugs, vitamin preparations, food supplements etc.
  3. Personalized blister pack according to Claim 1 or 2, wherein additional usage data of the patient, concerning products which are not in the blister pack (20) such as drugs, vitamin preparations, food supplements etc., can be stored on the memory device (50).
  4. Personalized blister pack according to one of Claims 1 to 3, wherein the memory device (50) has a device for displaying the stored usage data.
  5. Personalized blister pack according to Claim 1, wherein the device (58) to generate a usage reminder signal is designed to generate an acoustic signal, a visual signal or a vibration alarm signal.
  6. Personalized blister pack according to Claim 1, wherein the usage reminder signal can be suppressed for a specified period.
  7. Personalized blister pack according to Claim 6, wherein the suppressed usage reminder signal can be output offset in time.
  8. Personalized blister pack according to one of Claims 1 to 7, having an acknowledgment button for acknowledgment of the product usage by the person.
  9. Personalized blister pack according to one of Claims 1 to 8, having a sensor device to detect that the relevant receiving compartments (22) are opened.
  10. Personalized blister pack according to one of Claims 1 to 9, wherein parameters of the usage reminder signal, in particular its volume, are adjustable.
  11. Personalized blister pack according to one of Claims 1 to 10, wherein personal identification data associated with the particular person are stored in the memory device (50).
  12. Personalized blister pack according to Claim 11, wherein the memory device (50) has an output device (58) to output the personal identification data.
  13. Personalized blister pack according to one of Claims 1 to 12, wherein the memory device (50) has an EPROM memory element (52).
  14. Personalized blister pack according to one of Claims 1 to 12, wherein the memory device (50) has an RFID memory element (52).
  15. Personalized blister pack according to one of Claims 1 to 12, wherein the memory device (50) is in the form of a flash memory element.
  16. Personalized blister pack according to one of Claims 1 to 15, wherein the memory device (50) is designed to store usage data including the products themselves, the form of usage, the dose, the usage period and usage times, and additional person-related and/or product-related information if required.
  17. Personalized blister pack according to Claim 16, wherein the memory device (50) is designed to store detailed usage times of the products in relation to meals.
  18. Personalized blister pack according to one of Claims 1 to 17, wherein the memory device (50) can be removed from the blister pack (20).
  19. Personalized blister pack according to one of Claims 1 to 18, wherein the memory device (50) has a carrying device (60).
  20. Personalized blister pack according to one of Claims 1 to 19, wherein the memory device (50) has a waterproof, washable and shockproof case.
  21. Personalized blister pack according to one of Claims 1 to 20, wherein the memory device (50) is designed to be used once.
  22. Personalized blister pack according to one of Claims 1 to 20, wherein the memory device (50) has a memory element (52) which can be written many times, for multiple use of the memory device (50).
  23. Personalized blister pack according to Claim 22, wherein the memory device (50) has an interface (54) for updating the usage data.
  24. Personalized blister pack according to Claim 1, having a hinged lid which is formed on the blister pack (20) to cover the foil (25), and with labelling surfaces for printing usage information.
  25. Personalized blister pack according to one of Claims 1 to 24, wherein the defined period is a week, and the blister pack (20) is in the form of a weekly blister for the needs of one week.
  26. Personalized blister pack according to one of Claims 1 to 25, which is provided with an identifier (29) which is associated with the particular person.
  27. Personalized blister pack according to Claim 26, wherein the identifier (29) is in the form of a printed identifier, e.g. a barcode.
  28. Method of automatically packaging an individually defined product combination, in particular drugs, for numerous persons for a defined period, having the steps of:
    - capturing individual product usage data of each of the numerous persons and storing them in a database (80),
    - reading the usage data associated with a person for the defined period from the database (80), and on the basis of the read usage data,
    - preparing and automatically packaging the appropriate product combination in a person-specific blister pack (20), the receiving compartments (22) of the blister pack (20) being disposed in matrix form, with a number of rows for usage days separable from the blister pack by means of perforation sections (24), and columns for usage times during the day, said receiving compartments (22) being filled with the correspondingly ordered products,
    - storing the read usage data on a person-specific memory device (50), which memory device (50) includes a usage reminder function based on the stored usage data, and
    - attaching the memory devices (50) to the appropriate person-specific packaging units (20).
  29. Method according to Claim 28, wherein the product combination includes products like drugs, vitamin preparations, food supplements, etc.
  30. Method according to Claim 28 or 29, wherein additional usage data of the person, concerning products which are not in the blister pack (20) such as drugs, vitamin preparations, food supplements, etc., are stored on the memory device (50).
  31. Method according to one of Claims 28 to 30, wherein the drug packaging units (20) and the memory devices (50) are supplied together.
  32. Method according to one of Claims 28 to 31, wherein the usage data include the products themselves, the form of usage, the dose, the usage period and usage times, and additional person-related and/or product-related information if required.
  33. Method according to Claim 32, wherein the usage times include detailed usage data for the products in relation to meals.
  34. Method according to Claim 28, wherein all products which are required for one person, and can be transported in the blister pack (20), are supplied to the person by means of the packaging unit (20).
  35. Method according to one of Claims 28 to 34, wherein the defined period is one week.
  36. Method according to one of Claims 28 to 35, wherein the usage reminder function takes place by an acoustic, visual or vibration signal.
  37. Method according to one of Claims 28 to 36, wherein the programmable memory device (50) is used multiple times.
  38. Method according to one of Claims 28 to 37, wherein the usage data which are stored on the memory device (50) are updated by remote data transmission.
  39. Method according to Claim 38, wherein the updating takes place via the mobile communication network, wireless LAN or the Internet.
  40. Method according to one of Claims 28 to 39, wherein personal identification data associated with the defined person are stored in the memory device (50).
  41. Method according to one of Claims 28 to 40, wherein the packaging unit (20) is provided with an identifier (29) which is associated with the particular person.
  42. Method according to Claims 40 and 41, having the method step of checking that the personal identification data stored in the memory device agree with the identifier (29) which is attached to the packaging unit.
EP20060116277 2006-06-29 2006-06-29 Personalized blister pack and method for automated packaging of an individually determined composition Not-in-force EP1872765B1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE200650003608 DE502006003608D1 (en) 2006-06-29 2006-06-29 Personalized blister pack and method for automatically packaging an individualized product composition
AT06116277T ATE429893T1 (en) 2006-06-29 2006-06-29 PERSONALIZED BLISTER PACK AND METHOD FOR AUTOMATICALLY PACKAGING AN INDIVIDUALLY SPECIFIED PRODUCT COMPOSITION
EP20060116277 EP1872765B1 (en) 2006-06-29 2006-06-29 Personalized blister pack and method for automated packaging of an individually determined composition
DK06116277T DK1872765T3 (en) 2006-06-29 2006-06-29 Personalized blister packing and method for automatically packing an individually determined product combination
ES06116277T ES2326333T3 (en) 2006-06-29 2006-06-29 PERSONALIZED BLISTER CONTAINER AND AUTOMATIC PACKAGING PROCEDURE FOR AN INDIVIDUALLY ESTABLISHED PRODUCT COMBINATION.
PL06116277T PL1872765T3 (en) 2006-06-29 2006-06-29 Personalized blister pack and method for automated packaging of an individually determined composition
JP2009517203A JP2009540989A (en) 2006-06-29 2007-06-28 Personal blister pack
ES07786876T ES2440486T3 (en) 2006-06-29 2007-06-28 Custom blister pack
EP20070786876 EP2032113B1 (en) 2006-06-29 2007-06-28 Personalized blister pack
US12/306,781 US20090277815A1 (en) 2006-06-29 2007-06-28 Personalized blister pack
PCT/EP2007/056469 WO2008000790A1 (en) 2006-06-29 2007-06-28 Personalized blister pack
HK08103565A HK1109329A1 (en) 2006-06-29 2008-03-31 Personalized blister pack and method for automated packaging of an individually determined composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20060116277 EP1872765B1 (en) 2006-06-29 2006-06-29 Personalized blister pack and method for automated packaging of an individually determined composition

Publications (2)

Publication Number Publication Date
EP1872765A1 EP1872765A1 (en) 2008-01-02
EP1872765B1 true EP1872765B1 (en) 2009-04-29

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EP20060116277 Not-in-force EP1872765B1 (en) 2006-06-29 2006-06-29 Personalized blister pack and method for automated packaging of an individually determined composition
EP20070786876 Not-in-force EP2032113B1 (en) 2006-06-29 2007-06-28 Personalized blister pack

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Application Number Title Priority Date Filing Date
EP20070786876 Not-in-force EP2032113B1 (en) 2006-06-29 2007-06-28 Personalized blister pack

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US (1) US20090277815A1 (en)
EP (2) EP1872765B1 (en)
JP (1) JP2009540989A (en)
AT (1) ATE429893T1 (en)
DE (1) DE502006003608D1 (en)
DK (1) DK1872765T3 (en)
ES (2) ES2326333T3 (en)
HK (1) HK1109329A1 (en)
PL (1) PL1872765T3 (en)
WO (1) WO2008000790A1 (en)

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ES2326333T3 (en) 2009-10-07
HK1109329A1 (en) 2008-06-06
ES2440486T3 (en) 2014-01-29
JP2009540989A (en) 2009-11-26
PL1872765T3 (en) 2009-10-30
WO2008000790A1 (en) 2008-01-03
EP1872765A1 (en) 2008-01-02
US20090277815A1 (en) 2009-11-12
DK1872765T3 (en) 2009-08-17
ATE429893T1 (en) 2009-05-15
EP2032113B1 (en) 2013-10-30
DE502006003608D1 (en) 2009-06-10
EP2032113A1 (en) 2009-03-11

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