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EP1868577A4 - Lacidipine particles - Google Patents

Lacidipine particles

Info

Publication number
EP1868577A4
EP1868577A4 EP06749977A EP06749977A EP1868577A4 EP 1868577 A4 EP1868577 A4 EP 1868577A4 EP 06749977 A EP06749977 A EP 06749977A EP 06749977 A EP06749977 A EP 06749977A EP 1868577 A4 EP1868577 A4 EP 1868577A4
Authority
EP
European Patent Office
Prior art keywords
lacidipine
particles
lacidipine particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06749977A
Other languages
German (de)
French (fr)
Other versions
EP1868577A1 (en
Inventor
Venkataraman Sundaram
Manoj Ramesh Kharkar
Sharat Pandurang Narasapur
Surya Narayana Devarkonda
Suhas Lalitadas Jawlekar
Ravi Kumar Komareddy
Adolf Ceaser Goldwyn
Aniruddha Bhalachandra Pandit
Mamta Mishra
Arunava Ghosh
Gurvinder Singh
Vijay Dinanathji Nasare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Original Assignee
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Laboratories Ltd, Dr Reddys Laboratories Inc filed Critical Dr Reddys Laboratories Ltd
Publication of EP1868577A1 publication Critical patent/EP1868577A1/en
Publication of EP1868577A4 publication Critical patent/EP1868577A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
EP06749977A 2005-04-15 2006-04-13 Lacidipine particles Withdrawn EP1868577A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN432CH2005 2005-04-15
IN436CH2005 2005-04-15
US68466805P 2005-05-26 2005-05-26
US68469105P 2005-05-26 2005-05-26
PCT/US2006/013783 WO2006113309A1 (en) 2005-04-15 2006-04-13 Lacidipine particles

Publications (2)

Publication Number Publication Date
EP1868577A1 EP1868577A1 (en) 2007-12-26
EP1868577A4 true EP1868577A4 (en) 2009-12-09

Family

ID=37115465

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06749977A Withdrawn EP1868577A4 (en) 2005-04-15 2006-04-13 Lacidipine particles

Country Status (2)

Country Link
EP (1) EP1868577A4 (en)
WO (1) WO2006113309A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140031557A1 (en) * 2011-04-18 2014-01-30 Hefeibeinie Medical Technology Company, Ltd. Method for purification of calcium channel blockers of dihydorpyridine type and preparation of nanoparticles thereof
ITMI20131485A1 (en) 2012-09-10 2014-03-11 Rivopharm Sa PHARMACEUTICAL COMPOSITION INCLUDING LACIPIDINE AND PREPARATION PROCESS

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011848A (en) * 1984-08-22 1991-04-30 Glaxo, S.P.A. 1.4-dihydro pyridines
WO2003101624A1 (en) * 2002-05-28 2003-12-11 Battelle Memorial Institute Electrostatic deposition of particles generated from rapid expansion of supercritical fluid solutions
WO2004009057A1 (en) * 2002-07-18 2004-01-29 Astrazeneca Ab Process for the preparation of crystalline nano-particle dispersions
WO2005014069A1 (en) * 2003-08-05 2005-02-17 Phoqus Pharmaceuticals Limited Coating of surgical devices

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1244728B (en) * 1991-02-13 1994-08-08 Glaxo Spa MEDICAL USE OF DIHYDROPYRIDINE DERIVATIVES
SE9501384D0 (en) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
GB9828721D0 (en) 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
GB0016040D0 (en) 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
BR0209433A (en) 2001-05-05 2004-08-03 Accentus Plc Method for crystallization and apparatus
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
GB0125604D0 (en) 2001-10-25 2001-12-19 Glaxo Group Ltd Novel process
US20050095267A1 (en) * 2002-12-04 2005-05-05 Todd Campbell Nanoparticle-based controlled release polymer coatings for medical implants

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011848A (en) * 1984-08-22 1991-04-30 Glaxo, S.P.A. 1.4-dihydro pyridines
WO2003101624A1 (en) * 2002-05-28 2003-12-11 Battelle Memorial Institute Electrostatic deposition of particles generated from rapid expansion of supercritical fluid solutions
WO2004009057A1 (en) * 2002-07-18 2004-01-29 Astrazeneca Ab Process for the preparation of crystalline nano-particle dispersions
WO2005014069A1 (en) * 2003-08-05 2005-02-17 Phoqus Pharmaceuticals Limited Coating of surgical devices

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006113309A1 *

Also Published As

Publication number Publication date
EP1868577A1 (en) 2007-12-26
WO2006113309A1 (en) 2006-10-26

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20071025

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: NASARE, VIJAY DINANATHJI

Inventor name: SINGH, GURVINDER

Inventor name: GHOSH, ARUNAVA

Inventor name: MISHRA, MAMTA

Inventor name: PANDIT, ANIRUDDHA BHALACHANDRA

Inventor name: GOLDWYN, ADOLF CEASER

Inventor name: KOMAREDDY, RAVI KUMAR

Inventor name: JAWLEKAR, SUHAS LALITADAS

Inventor name: DEVARKONDA, SURYA NARAYANA

Inventor name: NARASAPUR, SHARAT PANDURANGHOUSE NO. 8-7-193/47, "

Inventor name: KHARKAR, MANOJ RAMESH

Inventor name: SUNDARAM, VENKATARAMAN

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20091111

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/455 20060101ALI20091105BHEP

Ipc: A61K 31/435 20060101ALI20091105BHEP

Ipc: A61K 9/20 20060101ALI20091105BHEP

Ipc: A61K 9/16 20060101ALI20091105BHEP

Ipc: A61K 9/14 20060101AFI20061110BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: DR. REDDY'S LABORATORIES INC.

Owner name: DR. REDDY'S LABORATORIES LTD.

17Q First examination report despatched

Effective date: 20100319

TPAC Observations filed by third parties

Free format text: ORIGINAL CODE: EPIDOSNTIPA

17Q First examination report despatched

Effective date: 20111004

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120215