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EP1695699A4 - Drug-containing grains and solid preparation containing the grains - Google Patents

Drug-containing grains and solid preparation containing the grains

Info

Publication number
EP1695699A4
EP1695699A4 EP04820201A EP04820201A EP1695699A4 EP 1695699 A4 EP1695699 A4 EP 1695699A4 EP 04820201 A EP04820201 A EP 04820201A EP 04820201 A EP04820201 A EP 04820201A EP 1695699 A4 EP1695699 A4 EP 1695699A4
Authority
EP
European Patent Office
Prior art keywords
grains
drug
solid preparation
preparation containing
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04820201A
Other languages
German (de)
French (fr)
Other versions
EP1695699A1 (en
Inventor
K Fujiwara
Kiyomi Sogo
S Okamoto
K Shibamori
N Shimono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Publication of EP1695699A1 publication Critical patent/EP1695699A1/en
Publication of EP1695699A4 publication Critical patent/EP1695699A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP04820201A 2003-12-09 2004-12-07 Drug-containing grains and solid preparation containing the grains Withdrawn EP1695699A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003410961 2003-12-09
PCT/JP2004/018204 WO2005055989A1 (en) 2003-12-09 2004-12-07 Drug-containing grains and solid preparation containing the grains

Publications (2)

Publication Number Publication Date
EP1695699A1 EP1695699A1 (en) 2006-08-30
EP1695699A4 true EP1695699A4 (en) 2012-08-22

Family

ID=34674963

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04820201A Withdrawn EP1695699A4 (en) 2003-12-09 2004-12-07 Drug-containing grains and solid preparation containing the grains

Country Status (7)

Country Link
US (1) US8153161B2 (en)
EP (1) EP1695699A4 (en)
JP (1) JP4740740B2 (en)
KR (1) KR20060126688A (en)
CN (1) CN1913876B (en)
TW (1) TWI335228B (en)
WO (1) WO2005055989A1 (en)

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CN100366294C (en) * 2004-04-30 2008-02-06 量子高科(北京)研究院有限公司 Oral cavity quick dissolving preparation and production method thereof
EP1913935A1 (en) * 2005-01-21 2008-04-23 Teva Pharmaceutical Industries Ltd Stable pharmaceutical formulations of zonisamide and methods for their manufacture
US8729085B2 (en) 2005-05-26 2014-05-20 Dainippon Sumitomo Pharma Co., Ltd. Pharmaceutical composition
TWI383809B (en) * 2005-06-29 2013-02-01 Otsuka Pharma Co Ltd Orally disintegrating powder comprising cilostazol
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
FR2915658B1 (en) * 2007-05-02 2013-10-11 Jean Francois Joseph Michel Letavernier EMPLOYMENT OF MANNITOL FOR THE MODULATION OF GUSTATIVE AND OLFACTIVE PERCEPTIONS OF FOOD, BEVERAGES AND FOOD SUPPLEMENTS
US9314454B2 (en) 2007-12-28 2016-04-19 Sawai Pharmaceutical Co., Ltd. Oral cavity disintegrating tablet and method of producing the same
KR101612137B1 (en) 2008-02-13 2016-04-12 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Orally disintegrating tablets
AU2009214193A1 (en) * 2008-02-13 2009-08-20 Bayer Intellectual Property Gmbh Estradiol-containing drug delivery system
BRPI0908231A2 (en) * 2008-02-13 2015-07-21 Bayer Schering Pharma Akltiengesellschaft Stabilizing drug release system
JP5594285B2 (en) * 2009-03-16 2014-09-24 ニプロ株式会社 Orally disintegrating tablets
EP2433652B1 (en) 2009-05-20 2016-11-09 Sumitomo Dainippon Pharma Co., Ltd. Dry-coated orally-disintegrating tablet
EP2465540B1 (en) 2009-08-11 2016-10-05 Fuji Chemical Industry Co., Ltd. Disintegrating particle composition and orally rapidly disintegrating tablet
US9446055B2 (en) 2009-08-11 2016-09-20 Fuji Chemical Industry Co., Ltd. Disintegrating particle composition and orally rapidly disintegrating tablet
US8591955B2 (en) 2009-08-11 2013-11-26 Dainippon Sumitomo Pharma Co., Ltd. Orally rapidly disintegrating tablet that contains two or more types of particles
UY32836A (en) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag STABILIZED PARTICLES THAT INCLUDE 5-METHYL- (6S) -TETRAHYDROPHOLATE
EP2467126A1 (en) 2009-08-19 2012-06-27 Bayer Pharma Aktiengesellschaft Drug delivery systems (wafer) for pediatric use
ES2713330T3 (en) 2009-12-11 2019-05-21 Sumitomo Dainippon Pharma Co Ltd Dry-coated tablet that disintegrates orally
JP4803686B2 (en) * 2010-08-31 2011-10-26 協和発酵キリン株式会社 Granules and orally disintegrating tablets containing a bitter-tasting drug
JP2012201597A (en) * 2011-03-23 2012-10-22 Nihon Generic Co Ltd Solid preparation comprising mosapride
WO2014142616A1 (en) * 2013-03-15 2014-09-18 한국유나이티드제약 주식회사 Mosapride sustained-release preparation for providing pharmacological clinical effects with once-a-day administration
TWI659752B (en) * 2013-03-26 2019-05-21 日商橘生藥品工業股份有限公司 Oral administration preparations masking the bitter taste of silodosin
JP6096328B2 (en) * 2014-02-10 2017-03-15 富士フイルム株式会社 Orally disintegrating tablets
JP6778051B2 (en) * 2016-08-18 2020-10-28 沢井製薬株式会社 Oseltamivir phosphate-containing pharmaceutical composition
CN112972398A (en) * 2021-02-25 2021-06-18 江苏睿实生物科技有限公司 Berberine hydrochloride granules and preparation method thereof
CN115089550B (en) * 2022-08-04 2024-03-08 浙江亚太药业股份有限公司 Preparation method of mosapride citrate particles

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JPS56164122A (en) 1980-05-21 1981-12-17 Fujimoto Seiyaku Kk Drug composition comprising cimetidine as main agent
JPS5858145A (en) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd Microcapsule with fast releasability and preparation thereof
CZ284687B6 (en) * 1986-04-30 1999-02-17 Dainippon Pharmaceutical Co., Ltd. Substituted benzamide derivative, process of its preparation and pharmaceutical composition based thereon
JPH058145A (en) 1991-07-02 1993-01-19 Suzuki Motor Corp Work pallet carrying in/out device
JPH0517360A (en) * 1991-07-08 1993-01-26 Sumitomo Pharmaceut Co Ltd Method for preparing solid preparation containing gefarnate
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JP2004026675A (en) * 2002-06-21 2004-01-29 Lion Corp Particle for chewable type medicinal preparation, chewable type medicinal preparation using the same, and method for suppressing unpleasant taste of the same
JP4501024B2 (en) * 2002-11-14 2010-07-14 小林製薬株式会社 Composition with reduced bitterness and odor of cysteines
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Non-Patent Citations (1)

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Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
TWI335228B (en) 2011-01-01
JP4740740B2 (en) 2011-08-03
US20070148230A1 (en) 2007-06-28
CN1913876B (en) 2013-06-26
JPWO2005055989A1 (en) 2007-08-23
TW200522980A (en) 2005-07-16
KR20060126688A (en) 2006-12-08
WO2005055989A1 (en) 2005-06-23
EP1695699A1 (en) 2006-08-30
US8153161B2 (en) 2012-04-10
CN1913876A (en) 2007-02-14

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Legal Events

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Effective date: 20120723

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Ipc: A61K 47/26 20060101ALI20120717BHEP

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Effective date: 20140701