EP1682567A4 - Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast - Google Patents

Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast

Info

Publication number: EP1682567A4
Authority: EP; European Patent Office
Prior art keywords: delta12; fatty acids; polyunsaturated fatty; oleaginous yeast; altering levels
Prior art date: 2003-11-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP04810970A

Other languages

German (de)

French (fr)

Other versions

EP1682567B1 (en

EP1682567A2 (en

Inventor

Narendra S Yadav

Quinn Qun Zhu

Hongxiang Zhang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

EIDP Inc

Original Assignee

EI Du Pont de Nemours and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-11-12

Filing date

2004-11-12

Publication date

2007-05-30

2004-11-12 Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co

2006-07-26 Publication of EP1682567A2 publication Critical patent/EP1682567A2/en

2007-05-30 Publication of EP1682567A4 publication Critical patent/EP1682567A4/en

2013-02-13 Application granted granted Critical

2013-02-13 Publication of EP1682567B1 publication Critical patent/EP1682567B1/en

2024-11-12 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nutrition Science (AREA)
Plant Pathology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

EP04810970A 2003-11-12 2004-11-12 Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast Ceased EP1682567B1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US51919103P	2003-11-12	2003-11-12
US57067904P	2004-05-13	2004-05-13
PCT/US2004/038034 WO2005047485A2 (en)	2003-11-12	2004-11-12	Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast

Publications (3)

Publication Number	Publication Date
EP1682567A2 EP1682567A2 (en)	2006-07-26
EP1682567A4 true EP1682567A4 (en)	2007-05-30
EP1682567B1 EP1682567B1 (en)	2013-02-13

Family

ID=34594953

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP04810970A Ceased EP1682567B1 (en)	2003-11-12	2004-11-12	Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast

Country Status (6)

Country	Link
US (1)	US7504259B2 (en)
EP (1)	EP1682567B1 (en)
JP (1)	JP4718477B2 (en)
AU (1)	AU2004290076B2 (en)
CA (1)	CA2541216C (en)
WO (1)	WO2005047485A2 (en)

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CN103451246B (en) *	2004-04-22	2018-02-16	联邦科学技术研究组织	With recombinant cell synthesis of long-chain polyunsaturated fatty acids
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US7465564B2 (en) *	2004-08-10	2008-12-16	E.I. Du Pont De Nemours And Company	Production of γ-linolenic acid in oleaginous yeast
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BRPI0806354A2 (en)	2007-02-12	2011-09-06	Du Pont	transgender oilseeds, seeds, oils, food or food analogues, medicinal food products or medicinal food analogues, pharmaceuticals, beverage formulas for babies, nutritional supplements, pet food, aquaculture feed, animal feed, whole seed products , mixed oil products, partially processed products, by-products and by-products
MX2009010574A (en)	2007-04-03	2009-10-22	Du Pont	Multizymes and their use in making polyunsaturated fatty acids.
EP2152849B1 (en)	2007-06-01	2013-02-20	Solazyme, Inc.	Production of oil in microorganisms
CN101970638B (en) *	2007-10-03	2015-02-11	纳幕尔杜邦公司	Optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
DK2198005T3 (en) *	2007-10-03	2014-07-21	Du Pont	Peroxisome Biogenesis Factor Protein (PEX) Breakage to Change the Contents of Polyunsaturated Fatty Acids and Total Lipid Content in Oily Eukaryotic Organisms
DK2310517T3 (en)	2008-07-11	2016-06-06	Inst Nat De La Rech Agronomique (Inra)	Novel mutant yeast strains having a capability to accumulate a large amount of lipids
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BRPI0913138A2 (en) *	2008-08-29	2016-05-31	Du Pont	transgenic eukaryotic oleaginous host cell, transgenic oleaginous eukaryotic yeast cell, oil or lipids, method for increasing the total lipid content of an oleaginous eukaryotic host cell and method for increasing the total polyunsaturated fatty acid content in the microbial oil
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WO2010147904A1 (en)	2009-06-16	2010-12-23	E. I. Du Pont De Nemours And Company	Improved optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
WO2010147900A1 (en)	2009-06-16	2010-12-23	E. I. Du Pont De Nemours And Company	IMPROVEMENT OF LONG CHAIN OMEGA-3 AND OMEGA-6 POLYUNSATURATED FATTY ACID BIOSYNTHESIS BY EXPRESSION OF ACYL-CoA LYSOPHOSPHOLIPID ACYLTRANSFERASES
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WO2011133610A1 (en)	2010-04-22	2011-10-27	E. I. Du Pont De Nemours And Company	Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
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CA2807834C (en)	2010-08-26	2019-06-25	E. I. Du Pont De Nemours And Company	Recombinant microbial host cells for high eicosapentaenoic acid production
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WO2003099216A2 (en) *	2002-05-22	2003-12-04	Monsanto Technology Llc	Fatty acid desaturases from fungi

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2004
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- 2004-11-12 JP JP2006539958A patent/JP4718477B2/en not_active Expired - Fee Related
- 2004-11-12 EP EP04810970A patent/EP1682567B1/en not_active Ceased
- 2004-11-12 AU AU2004290076A patent/AU2004290076B2/en not_active Ceased
- 2004-11-12 WO PCT/US2004/038034 patent/WO2005047485A2/en active Application Filing
- 2004-11-12 CA CA2541216A patent/CA2541216C/en not_active Expired - Fee Related

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Also Published As

Publication number	Publication date
CA2541216A1 (en)	2005-05-26
JP4718477B2 (en)	2011-07-06
WO2005047485A2 (en)	2005-05-26
AU2004290076A1 (en)	2005-05-26
AU2004290076B2 (en)	2009-03-12
JP2007510436A (en)	2007-04-26
US7504259B2 (en)	2009-03-17
EP1682567B1 (en)	2013-02-13
US20050216975A1 (en)	2005-09-29
CA2541216C (en)	2013-07-23
EP1682567A2 (en)	2006-07-26
WO2005047485A3 (en)	2006-02-23

Publication	Publication Date	Title
EP1682567A4 (en)	2007-05-30	Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
EP1682566A4 (en)	2007-05-30	Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
EP1620543A4 (en)	2008-11-19	Production of polyunsaturated fatty acids in oleaginous yeasts
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