[go: up one dir, main page]

EP1572987A4 - Acides nucleiques et polypeptides - Google Patents

Acides nucleiques et polypeptides

Info

Publication number
EP1572987A4
EP1572987A4 EP01907128A EP01907128A EP1572987A4 EP 1572987 A4 EP1572987 A4 EP 1572987A4 EP 01907128 A EP01907128 A EP 01907128A EP 01907128 A EP01907128 A EP 01907128A EP 1572987 A4 EP1572987 A4 EP 1572987A4
Authority
EP
European Patent Office
Prior art keywords
polypeptides
nucleic acids
novel nucleic
novel
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01907128A
Other languages
German (de)
English (en)
Other versions
EP1572987A2 (fr
Inventor
Y Tom Tang
Chenghua Liu
Radoje T Drmanac
Vinod Asundi
Ping Zhou
Chongjun Xu
Yicheng Cao
Yunquing Ma
Qing A Zhao
Dunrui Wang
Jian-Rui Wang
Jie Zhang
Feiyan Ren
Rui-Hong Chen
Zhi Wei Wang
Aidong J Xue
Yonghong Yang
Tom Wejhrman
Ryle Goodrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Nuvelo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/728,422 external-priority patent/US20020128187A1/en
Application filed by Nuvelo Inc filed Critical Nuvelo Inc
Publication of EP1572987A2 publication Critical patent/EP1572987A2/fr
Publication of EP1572987A4 publication Critical patent/EP1572987A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6432Coagulation factor Xa (3.4.21.6)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21006Coagulation factor Xa (3.4.21.6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP01907128A 2000-02-03 2001-02-05 Acides nucleiques et polypeptides Withdrawn EP1572987A4 (fr)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US728422 1991-07-11
US49691400A 2000-02-03 2000-02-03
US496914 2000-02-03
US56087500A 2000-04-27 2000-04-27
US560875 2000-04-27
US59807500A 2000-06-20 2000-06-20
US598075 2000-06-20
US62032500A 2000-07-19 2000-07-19
US620325 2000-07-19
US65493600A 2000-09-01 2000-09-01
US654936 2000-09-01
US66356100A 2000-09-15 2000-09-15
US663561 2000-09-15
US69332500A 2000-10-20 2000-10-20
US693325 2000-10-20
US09/728,422 US20020128187A1 (en) 2000-02-03 2000-11-30 Novel nucleic acids and polypeptides
PCT/US2001/004098 WO2001057190A2 (fr) 2000-02-03 2001-02-05 Acides nucleiques et polypeptides

Publications (2)

Publication Number Publication Date
EP1572987A2 EP1572987A2 (fr) 2005-09-14
EP1572987A4 true EP1572987A4 (fr) 2005-11-30

Family

ID=27575454

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01907128A Withdrawn EP1572987A4 (fr) 2000-02-03 2001-02-05 Acides nucleiques et polypeptides

Country Status (4)

Country Link
EP (1) EP1572987A4 (fr)
AU (1) AU2001234944A1 (fr)
CA (1) CA2399776A1 (fr)
WO (1) WO2001057190A2 (fr)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7057017B2 (en) 1997-04-16 2006-06-06 Millennium Pharmaceuticals, Inc. Human dickkopf-related protein and nucleic acid molecules and uses therefor
US7074897B2 (en) 1997-06-16 2006-07-11 Genentech, Inc. Pro943 polypeptides
US7446181B2 (en) 1998-01-15 2008-11-04 Millennium Pharmaceuticals, Inc. Antibodies that bind human Dickkopf-1 proteins
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
WO1999062941A2 (fr) 1998-06-01 1999-12-09 Urogenesys, Inc. Nouveaux antigenes transmembranaires du type serpentin exprimes dans des cancers humains et utilisation de ces antigenes
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6344541B1 (en) 1998-09-25 2002-02-05 Amgen Inc. DKR polypeptides
JP2002534112A (ja) 1999-01-15 2002-10-15 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 骨髄特異的タンパク質
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
AU3774300A (en) * 1999-06-02 2000-12-18 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2376404A1 (fr) * 1999-08-19 2001-03-01 Toshio Miyata Proteine meg-1
US20020042062A1 (en) 1999-09-24 2002-04-11 Mark Stearns Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
US7790861B2 (en) * 1999-09-24 2010-09-07 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
JP2003520031A (ja) * 1999-11-12 2003-07-02 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 28個のヒト分泌タンパク質
WO2001046454A1 (fr) 1999-12-23 2001-06-28 Cor Therapeutics, Inc. Recepteur p2y12
WO2003048326A2 (fr) * 2001-12-03 2003-06-12 Nuvelo, Inc. Procedes et matieres associes a de nouveaux polypeptides et polynucleotides
WO2001059079A1 (fr) 2000-02-11 2001-08-16 Glycozym Aps UDP-GALACTOSE : β-D-GALACTOSE-R 4-α-D-GALACTOSYLTRANSFERASE, α4GAL-T1
JP4342069B2 (ja) * 2000-02-14 2009-10-14 生化学工業株式会社 α1,4−ガラクトース転移酵素およびそれをコードするDNA
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1698697A3 (fr) * 2000-03-24 2006-09-13 Takeda Pharmaceutical Company Limited Protéine contenant SSD, son procédé de préparation et son utilisation
CA2405104A1 (fr) * 2000-04-05 2001-10-18 Kirin Beer Kabushiki Kaisha Methodes et materiaux relatifs a de nouveaux polypeptides et polynucleotides du type facteur de croissance des cellules-souches
AU2001268967A1 (en) * 2000-04-18 2001-10-30 Bayer Aktiengesellschaft Regulation of human epithin-like serine protease
AU2001257407A1 (en) * 2000-04-26 2001-11-07 Millennium Pharmaceuticals, Inc. 21657, a human short-chain dehydrogenase and uses thereof
US7510845B2 (en) 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
US7117033B2 (en) 2000-05-08 2006-10-03 Brainsgate, Ltd. Stimulation for acute conditions
JP2003532416A (ja) * 2000-05-09 2003-11-05 バイエル アクチェンゲゼルシャフト 内皮分化遺伝子6様gタンパク質共役受容体
AU2001263493A1 (en) * 2000-05-26 2001-12-11 Millennium Pharmaceuticals, Inc. 50250, a novel human lipase and uses thereof
WO2001096375A2 (fr) * 2000-06-16 2001-12-20 Millennium Pharmaceuticals, Inc. La 33358, nouveau membre de la famille humaine des ankyrines et ses utilisations
WO2001098354A2 (fr) * 2000-06-21 2001-12-27 Incyte Genomics, Inc. Recepteurs
EP1325114A2 (fr) * 2000-06-26 2003-07-09 Millennium Pharmaceuticals, Inc. 46619, une nouvelle synthase beta-cetoacyle et utilisations de cette derniere
AU2001281933A1 (en) * 2000-06-30 2002-01-14 Ingenium Pharmaceuticals Ag Human g protein-coupled receptor igpcr17, and uses therof
WO2002006312A2 (fr) * 2000-07-13 2002-01-24 Novartis Ag Gene associe a une maladie
WO2002008392A2 (fr) * 2000-07-25 2002-01-31 Bayer Aktiengesellschaft Regulation de la serine protease humaine semblable a matriptase
EP1307557A2 (fr) 2000-08-02 2003-05-07 The Johns Hopkins University Profils d'expression de cellules endotheliales
EP1315431A1 (fr) * 2000-08-02 2003-06-04 Millennium Pharmaceuticals, Inc. Membre de la famille du facteur de liberation du gtp humain (15368) et ses utilisations
CN1310942C (zh) * 2000-08-04 2007-04-18 路德维希癌症研究院 校正基因
EP1688496A3 (fr) * 2000-08-14 2006-08-16 Actimis Pharmaceuticals, Inc., Régulation du récepteur couple aux protéines g du type récepteur p2y1
US20040038879A1 (en) * 2000-08-14 2004-02-26 Shyam Ramakrishnan Regulation of human p2y1-like g protein-coupled receptor
US20020156259A1 (en) * 2000-08-15 2002-10-24 Conklin Darrell C. Human adenosine deaminase
WO2002016586A2 (fr) * 2000-08-21 2002-02-28 Bristol-Myers Squibb Company Nouvel homologue d'adenosine deaminase
US20030166300A1 (en) * 2000-08-30 2003-09-04 Tang Y. Tom Growth-related inflammatory and immune response protein
WO2002018552A2 (fr) * 2000-08-30 2002-03-07 Bayer Aktiengesellschaft Regulation d'enzyme humaine de type aminotransferase
US20040072185A1 (en) * 2000-09-15 2004-04-15 Patrizia Paterlini-Brechot Cellular genes involved in oncogenesis, products of said genes and their diagnostic and therapeutic uses
US7754435B2 (en) * 2000-09-21 2010-07-13 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
AU2002211502A1 (en) * 2000-10-04 2002-04-15 Curagen Corporation Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
AU2002220613A1 (en) * 2000-10-11 2002-04-22 Bayer Aktiengesellschaft Regulation of human cyclophilin-type peptidyl-prolyl cis-trans isomerase
US6984502B2 (en) 2000-10-19 2006-01-10 Millennium Pharmaceuticals, Inc. Methods and compositions of human 69087 nucleic acids and uses thereof
WO2002036625A2 (fr) 2000-11-03 2002-05-10 The Regents Of The University Of California Polypeptides de prokineticine, et methodes et compositions associees
US20030009017A1 (en) * 2000-11-08 2003-01-09 Leiby Kevin R. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
WO2002038743A2 (fr) * 2000-11-09 2002-05-16 Glaxo Group Limited Enzyme
US7129057B2 (en) * 2000-11-09 2006-10-31 University Of Virginia Patent Foundation Human testis specific serine/threonine kinase 3
US7312086B2 (en) 2000-12-07 2007-12-25 Bristol-Myers Squibb Company Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
WO2002050279A2 (fr) * 2000-12-21 2002-06-27 Incyte Genomics, Inc. Proteines associees a un acide nucleique
US7892730B2 (en) * 2000-12-22 2011-02-22 Sagres Discovery, Inc. Compositions and methods for cancer
US20030148920A1 (en) * 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002053719A2 (fr) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Proteines associees au cytosquelette
US20040126759A1 (en) * 2001-01-05 2004-07-01 Baughn Mariah R. Molecules for disease detection and treatment
US6319679B1 (en) * 2001-01-26 2001-11-20 Board Of Regents, The University Of Texas System PAS kinase
US20020115136A1 (en) * 2001-02-07 2002-08-22 Gennady Merkulov Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
AU2002247716A1 (en) * 2001-02-14 2002-08-28 Axaron Bioscience Ag Proteins 7b6 and 11b4 and dna sequences encoding the same
JP2005508606A (ja) * 2001-03-16 2005-04-07 インサイト・ゲノミックス・インコーポレイテッド 核酸関連タンパク質
US20030044813A1 (en) * 2001-03-30 2003-03-06 Old Lloyd J. Cancer-testis antigens
US20020146795A1 (en) * 2001-04-02 2002-10-10 Shiaoping Zhu Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
US7927597B2 (en) * 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
EP2280030A3 (fr) 2001-04-10 2011-06-15 Agensys, Inc. Acides nucléiques et protéines correspondantes utiles dans la détection et le traitement des différents cancers
US6962811B2 (en) 2001-05-09 2005-11-08 Millennium Pharmaceuticals, Inc. 14715, a human fringe family member nucleic acids and uses therefor
ATE479748T1 (de) 2001-05-29 2010-09-15 Human Cell Systems Inc Testikulärer carnitintransporter und sein gen
AU2002320264B2 (en) 2001-06-05 2008-05-01 Exelixis, Inc. GFATs as modifiers of the p53 pathway and methods of use
EP2000545B1 (fr) * 2001-06-20 2011-08-31 Genentech, Inc. Compositions et procédés pour le traitement et le diagnostic d'une tumeur pulmonaire
AU2002319261A1 (en) * 2001-06-25 2003-01-08 Bayer Aktiengesellschaft Regulation of human serine/threonine protein kinase nek3
ES2532757T3 (es) 2001-09-06 2015-03-31 Agensys, Inc. Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
DE50209201D1 (de) * 2001-09-24 2007-02-15 Gruenenthal Gmbh Screeningverfahren für verschiedene Indikationen mit DNPI
US7265214B2 (en) * 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
EP1512007A4 (fr) * 2001-10-29 2005-08-17 Millennium Pharm Inc 32235, membre de la famille de l'aminotransferase humaine et ses utilisations
JP2005508633A (ja) * 2001-10-31 2005-04-07 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 32616を用いる腫瘍形成障害および脈管形成障害の処置法および診断法
US20030143231A1 (en) * 2001-10-31 2003-07-31 Millennium Pharmaceuticals, Inc. Methods and compositions for the treatment and diagnosis of pain disorders using 57749
DE60220621T2 (de) 2001-11-09 2008-03-06 Proteologics, Inc. Posh Nukleinsäure, Polypeptide und darauf bezogene Verfahren
AU2002356624A1 (en) * 2001-12-04 2003-06-17 Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung Ptp10d, tec and edtp involved in triglycerid-metabolism
AU2002357163A1 (en) * 2001-12-12 2003-07-09 University Of Cincinnati Apyrase polypeptides and nucleic acids encoding same
ES2337989T3 (es) * 2001-12-18 2010-05-03 Endocube Sas Nuevas proteinas asociadas a la muerte de la familia thap y rutas par4 relacionadas implicadas en el control de la apoptosis.
US7858297B2 (en) 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
AU2003244347A1 (en) * 2002-02-04 2003-09-02 Takeda Chemical Industries, Ltd. Angiogenesis inhibitors
GB0205112D0 (en) * 2002-03-05 2002-04-17 Pantherix Ltd Enzyme
JP4176022B2 (ja) 2002-03-11 2008-11-05 独立行政法人科学技術振興機構 実用的キラルジルコニウム触媒
DE10212397A1 (de) * 2002-03-20 2003-10-16 Universitaetsklinikum Freiburg Repressor der Skelettmuskeldifferenzierung, dafür kodierende Nucleinsäure und dessen Verwendung in Diagnostik und Therapie
US20050065082A1 (en) * 2002-03-29 2005-03-24 Hirofumi Doi C-jun phosphorylation inhibitors
US20050202431A1 (en) * 2002-04-01 2005-09-15 National Institute Of Advanced Industrial Science Application of kiaa0172 gene to treatment and diagnosis of diseases and drug discovery
US7622443B2 (en) 2002-04-26 2009-11-24 California Institute Of Technology Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides
WO2003091447A2 (fr) 2002-04-26 2003-11-06 California Institute Of Technology Acides nucleiques d1-1, polypeptides et methodes associees
DE10222845A1 (de) * 2002-05-23 2003-12-04 Dresden Arzneimittel Klonierung, Expression und Charakterisierung der Gesamtsequenz von Phosphodiesterase 8B
DE60334400D1 (de) * 2002-06-28 2010-11-11 Imclone Llc Neue polynukleotid- und polypeptidsequenzen und deren verwendungen
AU2003260312A1 (en) * 2002-07-19 2004-02-09 Cellzome Ag Protein complexes of the TIP60 transcriptional activator protein
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
JP2004290170A (ja) * 2002-08-02 2004-10-21 Takeda Chem Ind Ltd 疾患関連遺伝子の用途
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
US7561919B2 (en) 2002-11-14 2009-07-14 Brainsgate Ltd. SPG stimulation via the greater palatine canal
US20080213166A1 (en) * 2002-11-20 2008-09-04 Biogen Idec Inc. Novel Gene Targets and Ligands that Bind Thereto for Treatment and Diagnosis of Colon Carcinomas
AU2003300680A1 (en) * 2002-12-10 2004-07-09 Centre National De La Recherche Scientifique Cnrs Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation
JP4140951B2 (ja) * 2002-12-18 2008-08-27 独立行政法人科学技術振興機構 転写制御因子zhx3
EP2141235B1 (fr) 2002-12-29 2014-06-11 Toudai Tlo, Ltd. Récepteur de l'adiponectine et gène codant pour ce récepteur
JP2006518997A (ja) * 2003-01-21 2006-08-24 ブリストル−マイヤーズ スクイブ カンパニー 新規アシルコエンザイムa:モノアシルグリセロールアシルトランスフェラーゼ−3(mgat3)をコードするポリヌクレオチドおよびその用途
US7858346B2 (en) * 2003-02-03 2010-12-28 Japan Science Technology Agency Regeneration and neogenesis of retinal visual cell-expressing Otx2 protein
WO2005051988A2 (fr) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions et procedes permettant de traiter un lupus erythemateux systemique
EP1622571A4 (fr) * 2003-04-30 2012-05-02 Agensys Inc Acides nucleiques et proteines correspondantes appelees 109p1d4 utiles dans le traitement et la detection du cancer
WO2004104218A1 (fr) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Agents diagnostiques et therapeutiques destines a des maladies associees a x-prolyl aminopeptidase 1 (xpnpep1)
WO2005023855A2 (fr) * 2003-09-10 2005-03-17 Friedrich-Alexander-Uni- Versitatet Erlangen- Nuernberg Gene et proteine k203
JP4634302B2 (ja) * 2003-09-30 2011-02-16 第一三共株式会社 テトラヒドロ葉酸合成酵素遺伝子
WO2005059504A2 (fr) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics et therapeutique destines au traitement de maladies associees au recepteur couple aux proteines g gpr34 (gpr34)
EP1723414A4 (fr) 2004-01-16 2008-03-26 Merck & Co Inc Npc1l1 (npc3) et procedes pour identifier des ligands de ceux-ci
JP2007521835A (ja) * 2004-02-10 2007-08-09 トラスティーズ・オブ・ダートマウス・カレッジ ニコチンアミドリボシドキナーゼ組成物およびそれらの使用方法
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
AU2005223847A1 (en) * 2004-03-19 2005-09-29 Yale University Detection, isolation and uses of renalase (Monoamine Oxidase C)
CA2561577A1 (fr) * 2004-03-30 2005-10-13 Nsgene A/S Utilisation therapeutique d'un facteur de croissance, nsg33
US20050222040A1 (en) * 2004-04-05 2005-10-06 Blm Group, Inc. Vertebrate peptide modulators of lipid metabolism
PL1742966T3 (pl) 2004-04-22 2014-04-30 Agensys Inc Przeciwciała i pochodzące z nich cząsteczki, które wiążą się z białkami STEAP-1
US7709611B2 (en) 2004-08-04 2010-05-04 Amgen Inc. Antibodies to Dkk-1
WO2006069592A2 (fr) * 2004-12-31 2006-07-06 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Methode permettant de diagnostiquer et/ou de predire la toxemie preeclamptique et/ou des troubles associes
FI20050011L (fi) * 2005-01-05 2006-07-06 Jurilab Ltd Oy Menetelmä ja testipakkaus tyypin 2 diabetes mellituksen riskin havaitsemiseksi
WO2006074914A2 (fr) * 2005-01-13 2006-07-20 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Helicase d'arn humaine et ses utilisations therapeutiques
US7521195B1 (en) 2005-07-21 2009-04-21 Celera Corporation Lung disease targets and uses thereof
CA2630085A1 (fr) 2005-11-21 2007-05-24 Yale University Procedes de regulation de la renalase (monoamine oxydase c)
WO2007060899A1 (fr) * 2005-11-22 2007-05-31 National University Corporation Nagoya University Application d'une protéine se liant à l’actine à une maladie associée à la motilité cellulaire
EP1986489A2 (fr) 2006-02-24 2008-11-05 Schering Corporation Orthologues de npc1l1
RU2639543C9 (ru) 2006-10-27 2018-06-14 Дженентек, Инк. Антитела и иммуноконъюгаты и их применения
EP2152292A4 (fr) * 2007-05-02 2011-04-27 Snu R&Db Foundation Inhibiteur de l'angiogenèse comprenant de la météorine en tant que principe actif
CA2691378A1 (fr) 2007-07-02 2009-01-08 Oncomed Pharmaceuticals, Inc. Anticorps contre la r-spondine humaine et utilisation associee en vue de l'inhibition du signalement de beta-catenine et traitement du cancer
EP2170374A2 (fr) * 2007-07-03 2010-04-07 Andreas Reichert Procédé de traitement de maladies liées à un dysfonctionnement mitochondrial
WO2009014450A1 (fr) * 2007-07-24 2009-01-29 Sanare As Nouveaux peptides
CN101910196A (zh) 2007-12-28 2010-12-08 诺沃-诺迪斯克有限公司 Ddr1-介导的从它们的祖细胞向胰腺内分泌细胞的细胞纯化
JP5616888B2 (ja) 2008-07-24 2014-10-29 エヌエスジーン・アクティーゼルスカブNsGene A/S 成長因子metrnlの治療的使用
EP3255146B1 (fr) 2009-03-16 2019-05-15 Pangu Biopharma Limited Compositions et procedes comprenant des variants d'epissage d'histidyl-arnt synthetase presentant des activites biologiques non canoniques
AR075989A1 (es) 2009-04-10 2011-05-11 Lilly Co Eli Anticuerpo dkk -1 (dickkopf-1) humano disenado por ingenieria
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
RU2563359C2 (ru) 2009-11-30 2015-09-20 Дженентек, Инк. Композиции и способы для диагностики и лечения опухоли
CA2783731C (fr) 2009-12-11 2018-03-27 Atyr Pharma, Inc. Aminoacyl-arnt synthetases destinees a moduler une inflammation
EP2566492B1 (fr) 2010-05-04 2016-10-26 aTyr Pharma, Inc. Découverte innovante de compositions thérapeutiques liées à des fragments protéiques de glutamyl-prolyl-arnt-synthétases
US20130202576A1 (en) 2010-07-12 2013-08-08 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
CN103269708A (zh) 2010-10-01 2013-08-28 Ns基因公司 镍纹蛋白用于治疗异常性疼痛、痛觉过敏、自发性疼痛和幻痛的用途
CN104023746B (zh) 2011-07-15 2016-08-17 昂考梅德药品有限公司 Rspo结合剂和其应用
JP6145667B2 (ja) 2011-09-05 2017-06-14 ホーバ セラピューティクス アンパルトセルスカブ アロディニア、痛覚過敏、自発痛、及び幻痛の治療
EP3311847A1 (fr) 2012-02-16 2018-04-25 Atyr Pharma, Inc. Histidyl-arnt synthétases pour le traitement de maladies auto-immunes et inflammatoires
JP6335896B2 (ja) 2012-07-13 2018-05-30 オンコメッド ファーマシューティカルズ インコーポレイテッド Rspo3結合剤およびその使用法
EP2742935A1 (fr) * 2012-12-14 2014-06-18 Tissue Med Biosciences Forschungs- und Entwicklungsgesellschaft mbH SERF2 pour traiter l'atrophie ou augmenter la croissance cellulaire
JP6397479B2 (ja) 2013-03-15 2018-09-26 エータイアー ファーマ, インコーポレイテッド ヒスチジル−tRNAシンテターゼFcコンジュゲート
EP2878335B1 (fr) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant et système d'implantation pour stimulateur neural
EP3193935A4 (fr) 2014-09-16 2018-03-21 Oncomed Pharmaceuticals, Inc. Traitement de maladies fibrotiques
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
CN110049769A (zh) 2016-12-04 2019-07-23 阿拉维·霍拉萨尼·默哈达姆·马塞尔·维克托 治疗与线粒体应激相关的疾病的方法
WO2018176065A1 (fr) * 2017-03-23 2018-09-27 Oregon State University Compositions et méthodes destinées au traitement des maladies associées à l'atrophie musculaire
SG11201909218RA (en) 2017-04-03 2019-11-28 Hoffmann La Roche Antibodies binding to steap-1
CA3060514A1 (fr) 2017-04-20 2018-10-25 Atyr Pharma, Inc. Compositions et procedes pour le traitement d'inflammation pulmonaire
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
CN116685344A (zh) * 2020-12-08 2023-09-01 想象制药有限责任公司 治疗伤口的组合物和方法
US12252518B2 (en) 2023-01-06 2025-03-18 Life Biosciences, Inc. Methods of treating non-arteritic anterior ischemic optic neuropathy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (fr) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Lectine humaine de type c
WO1998054209A2 (fr) * 1997-05-31 1998-12-03 Peptide Therapeutics Limited Mafa humaine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (fr) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Lectine humaine de type c
WO1998054209A2 (fr) * 1997-05-31 1998-12-03 Peptide Therapeutics Limited Mafa humaine

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI 1 November 1996 (1996-11-01), XP002329122, retrieved from EBI Database accession no. Q04490 *
DATABASE EMBL [online] 15 November 1992 (1992-11-15), "Homo Sapiens P5-1 mRNA, complete cds.", XP002329509, retrieved from EBI Database accession no. HSMHP *
DATABASE EMBL [online] 19 January 1998 (1998-01-19), "nx26e06.s1 NCI_CGAP_GC4 Homo sapiens cDNA clone IMAGE:1257250 3', mRNA sequence.", XP002346073, retrieved from EBI Database accession no. AA742567 *
DATABASE EMBL [online] 25 January 1999 (1999-01-25), "CITBI-E1-2541D22.TR CITBI-E1 Homo sapiens genomic clone 2541D22, genomic survey sequence.", XP002346074, retrieved from EBI Database accession no. AQ356422 *
DATABASE EMBL [online] 27 August 1998 (1998-08-27), "Homo sapiens PAC clone RP4-701O16 from 7, complete sequence.", XP002346072, retrieved from EBI Database accession no. AC005531 *
DATABASE EMBL [online] 4 December 1998 (1998-12-04), "Homo sapiens DNA, P5-1-hom region.", XP002329406, retrieved from EBI Database accession no. D88650 *
DATABASE EMBL 21 April 1994 (1994-04-21), "H.sapiens P5-1g DNA", XP002329407, retrieved from EBI Database accession no. Z31714 *
DATABASE EMBL 30 June 1999 (1999-06-30), "wi73f11.x1 NCI_CGAP_Kid12 Homo sapiens cDNA clone IMAGE:2398989 3' similar to TR:Q04490 Q04490 P5-1 PROTEIN.", XP002329408, retrieved from EBI Database accession no. AI765329 *
DATABASE UniProt 1 June 1998 (1998-06-01), "Mast cell function-associated antigen", XP002346076, retrieved from EBI Database accession no. O43198 *
DATABASE UniProt 1 November 1998 (1998-11-01), "ITIM-containing receptor MAFA_l (Mast cell function-associated antigen homolog)", XP002346075, retrieved from EBI Database accession no. 075613 *
See also references of WO0157190A3 *
SHIINA TAKASHI ET AL.: "Physical mapping between the S and HLA-E genes in the human MHC class I region: Construction of a BAC, PAC, and cosmid contig", IMMUNOGENETICS, vol. 48, no. 6, November 1998 (1998-11-01), pages 402 - 407, XP002329404, ISSN: 0093-7711 *
VERNET C. ET AL.: "A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region", IMMUNOGENETICS, vol. 38, no. 1, 1993, pages 47 - 53, XP002904811, ISSN: 0093-7711 *

Also Published As

Publication number Publication date
WO2001057190A3 (fr) 2006-11-16
AU2001234944A1 (en) 2001-08-14
EP1572987A2 (fr) 2005-09-14
CA2399776A1 (fr) 2001-08-09
WO2001057190A2 (fr) 2001-08-09
AU2001234944A8 (en) 2006-12-21

Similar Documents

Publication Publication Date Title
AU2001234944A8 (en) Novel nucleic acids and polypeptides
AU2001249251A1 (en) Novel nucleic acids and polypeptides
AU2001243142A1 (en) Novel nucleic acids and polypeptides
AU2001290548A1 (en) Novel nucleic acids and polypeptides
AU2001245280A1 (en) Novel nucleic acids and polypeptides
AU2001233041A1 (en) Novel nucleic acids and polypeptides
AU2001238347A1 (en) Novel nucleic acids and polypeptides
AU2001296235A1 (en) Novel nucleic acids and polypeptides
AU2001263006A1 (en) Novel nucleic acids and polypeptides
IL206414A0 (en) Novel receptor nucleic acids and polypeptides
AU2001233017A1 (en) Novel nucleic acids and polypeptides
AU2002246502A1 (en) Nucleic acids and polypeptides
AU2001241511A1 (en) Novel nucleic acids and polypeptides
AU2001250872A1 (en) Novel nucleic acids and polypeptides
AU2001292561A1 (en) Nucleic acids and polypeptides
AU2001277840A1 (en) Novel nucleic acids and polypeptides
GB0002814D0 (en) Nucleic acids and their uses
AU8308901A (en) Novel proteins and nucleic acids encoding same
AU1181802A (en) Novel proteins and nucleic acids encoding same
AU2001239889A1 (en) Polypeptides and nucleic acids encoding same
AU7005801A (en) Gp354 nucleic acids and polypeptides
AU2001263005A8 (en) Novel nucleic acids and polypeptides
AU3099402A (en) Novel proteins and nucleic acids encoding same
AU2001252926A1 (en) Novel nucleic acids and polypeptides
AU7298201A (en) Gp286 nucleic acids and polypeptides

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020826

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

A4 Supplementary search report drawn up and despatched

Effective date: 20051012

PUAK Availability of information related to the publication of the international search report

Free format text: ORIGINAL CODE: 0009015

RIC1 Information provided on ipc code assigned before grant

Ipc: C07H 21/04 20060101AFI20070319BHEP

17Q First examination report despatched

Effective date: 20080328

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Effective date: 20080515