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EP1556022A4 - Aqueous 2,6-diisopropylphenol pharmaceutical compositions - Google Patents

Aqueous 2,6-diisopropylphenol pharmaceutical compositions

Info

Publication number
EP1556022A4
EP1556022A4 EP03759636A EP03759636A EP1556022A4 EP 1556022 A4 EP1556022 A4 EP 1556022A4 EP 03759636 A EP03759636 A EP 03759636A EP 03759636 A EP03759636 A EP 03759636A EP 1556022 A4 EP1556022 A4 EP 1556022A4
Authority
EP
European Patent Office
Prior art keywords
diisopropylphenol
aqueous
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03759636A
Other languages
German (de)
French (fr)
Other versions
EP1556022A1 (en
Inventor
Zhong Zhang
Orn Almarsson
Hongming Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transform Pharmaceuticals Inc
Original Assignee
Transform Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/629,308 external-priority patent/US7915317B2/en
Application filed by Transform Pharmaceuticals Inc filed Critical Transform Pharmaceuticals Inc
Publication of EP1556022A1 publication Critical patent/EP1556022A1/en
Publication of EP1556022A4 publication Critical patent/EP1556022A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP03759636A 2002-10-29 2003-10-02 Aqueous 2,6-diisopropylphenol pharmaceutical compositions Withdrawn EP1556022A4 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US629308 1996-04-08
US42219502P 2002-10-29 2002-10-29
US422195P 2002-10-29
US43697902P 2002-12-30 2002-12-30
US436979P 2002-12-30
US44349003P 2003-01-29 2003-01-29
US443490P 2003-01-29
US46245003P 2003-04-11 2003-04-11
US462450P 2003-04-11
US46431403P 2003-04-21 2003-04-21
US464314P 2003-04-21
US47040303P 2003-05-14 2003-05-14
US470403P 2003-05-14
US48535403P 2003-07-07 2003-07-07
US485354P 2003-07-07
US10/629,308 US7915317B2 (en) 2002-07-29 2003-07-29 Aqueous 2,6-diisopropylphenol pharmaceutical compositions
PCT/US2003/031086 WO2004039360A1 (en) 2002-10-29 2003-10-02 Aqueous 2,6-diisopropylphenol pharmaceutical compositions

Publications (2)

Publication Number Publication Date
EP1556022A1 EP1556022A1 (en) 2005-07-27
EP1556022A4 true EP1556022A4 (en) 2010-03-10

Family

ID=32234547

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03759636A Withdrawn EP1556022A4 (en) 2002-10-29 2003-10-02 Aqueous 2,6-diisopropylphenol pharmaceutical compositions

Country Status (3)

Country Link
EP (1) EP1556022A4 (en)
AU (1) AU2003275360A1 (en)
WO (1) WO2004039360A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7550155B2 (en) * 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
WO2020206258A1 (en) * 2019-04-05 2020-10-08 Sorrento Therapeutics, Inc. Cannabidiol pharmaceutical compositions
CN114601800B (en) * 2021-09-28 2023-07-28 天津瑞普生物技术股份有限公司 A kind of propofol sodium sterile powder injection and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056635A (en) * 1974-03-28 1977-11-01 Imperial Chemical Industries Limited 2,6-Diisopropylphenol as an anaesthetic agent
WO2000078301A1 (en) * 1999-06-21 2000-12-28 Kuhnil Pharm. Co., Ltd. Anesthetic composition for intravenous injection comprising propofol
WO2002009671A2 (en) * 2000-08-01 2002-02-07 University Of Florida Microemulsion and micelle systems for solubilizing drugs
WO2003030862A2 (en) * 2001-10-08 2003-04-17 Maelor Pharmaceuticals Limited Anaesthetic compositions and method for their administration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000010531A1 (en) * 1998-08-19 2000-03-02 Rtp Pharma Inc. Injectable aqueous dispersions of propofol

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056635A (en) * 1974-03-28 1977-11-01 Imperial Chemical Industries Limited 2,6-Diisopropylphenol as an anaesthetic agent
WO2000078301A1 (en) * 1999-06-21 2000-12-28 Kuhnil Pharm. Co., Ltd. Anesthetic composition for intravenous injection comprising propofol
WO2002009671A2 (en) * 2000-08-01 2002-02-07 University Of Florida Microemulsion and micelle systems for solubilizing drugs
WO2003030862A2 (en) * 2001-10-08 2003-04-17 Maelor Pharmaceuticals Limited Anaesthetic compositions and method for their administration

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2004039360A1 *

Also Published As

Publication number Publication date
AU2003275360A8 (en) 2004-05-25
EP1556022A1 (en) 2005-07-27
AU2003275360A1 (en) 2004-05-25
WO2004039360B1 (en) 2004-06-17
WO2004039360A1 (en) 2004-05-13

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