EP1549140A4 - Herstellung von peptiden in pflanzen als virush llproteinfusionen - Google Patents

Herstellung von peptiden in pflanzen als virush llproteinfusionen

Info

Publication number: EP1549140A4
Authority: EP; European Patent Office
Prior art keywords: hull; peptides; proteins; plants; production
Prior art date: 2002-09-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP03808079A

Other languages

English (en)

French (fr)

Other versions

EP1549140A2 (de

Inventor

Kenneth E Palmer

Rachel L Toth

Michael Jones

Sean Chapman

Lisa Smolenska

Alison Mccormick

Gregory Pogue

Long Nguyen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kentucky Bioprocessing LLC

Original Assignee

Kentucky Bioprocessing LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-03

Filing date

2003-09-03

Publication date

2009-04-29

2003-06-06 Priority claimed from US10/457,082 external-priority patent/US20040033585A1/en

2003-09-03 Application filed by Kentucky Bioprocessing LLC filed Critical Kentucky Bioprocessing LLC

2005-07-06 Publication of EP1549140A2 publication Critical patent/EP1549140A2/de

2009-04-29 Publication of EP1549140A4 publication Critical patent/EP1549140A4/de

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/23—Parvoviridae, e.g. feline panleukopenia virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/12011—Bunyaviridae
- C12N2760/12211—Phlebovirus, e.g. Rift Valley fever virus
- C12N2760/12222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Public Health (AREA)
Mycology (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

EP03808079A 2002-09-03 2003-09-03 Herstellung von peptiden in pflanzen als virush llproteinfusionen Withdrawn EP1549140A4 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US457082		1995-06-01
US40779502P	2002-09-03	2002-09-03
US407795P		2002-09-03
US10/457,082 US20040033585A1 (en)	2002-06-07	2003-06-06	Flexible vaccine assembly and vaccine delivery platform
PCT/US2003/027563 WO2004032622A2 (en)	2002-09-03	2003-09-03	Production of peptides in plants as viral coat protein fusions

Publications (2)

Publication Number	Publication Date
EP1549140A2 EP1549140A2 (de)	2005-07-06
EP1549140A4 true EP1549140A4 (de)	2009-04-29

Family

ID=32096072

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP03808079A Withdrawn EP1549140A4 (de)	2002-09-03	2003-09-03	Herstellung von peptiden in pflanzen als virush llproteinfusionen

Country Status (4)

Country	Link
EP (1)	EP1549140A4 (de)
AU (1)	AU2003296902A1 (de)
CA (1)	CA2497798A1 (de)
WO (1)	WO2004032622A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1926238A (zh)	2004-02-27	2007-03-07	陶氏化学公司	植物细胞中的高效肽生产
EP1732615A4 (de) *	2004-03-25	2009-09-16	Kentucky Bioproc Llc	Herstellung von peptiden in pflanzen als virushüllproteinfusion
AU2005323087A1 (en)	2004-12-30	2006-07-13	Schering-Plough Pty. Limited	Neutralizing epitope-based growth enhancing vaccine
WO2017217460A1 (ja) *	2016-06-15	2017-12-21	出光興産株式会社	ペプチドリンカーで連結された２以上のタンパク質を含む融合タンパク質
CN111351929B (zh) *	2020-01-15	2022-08-16	南京农业大学	基于单克隆抗体的黄瓜绿斑驳花叶病毒的快速检测试纸条

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991015587A1 (en) *	1990-04-06	1991-10-17	Commonwealth Scientific And Industrial Research Organisation	Self-polymerising expression system based on modified potyvirus coat proteins
WO1995031476A1 (en) *	1994-05-17	1995-11-23	The University Of Queensland	Recombinant papilloma virus l1
WO1996012028A1 (en) *	1994-10-14	1996-04-25	Biosource Technologies, Inc.	Production of peptides in plants as viral coat protein fusions
CA2355883A1 (en) *	1998-12-23	2000-07-06	Merck & Co., Inc.	Neutralizing assay using human papillomavirus virus-like particles
WO2001066778A2 (en) *	2000-03-08	2001-09-13	Large Scale Biology Corporation	Production of foreign polypeptides in plants as viral coat protein fusions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9108386D0 (en)	1991-04-19	1991-06-05	Agricultural Genetics Co	Modified plant viruses as vectors
US5667782A (en) *	1992-07-16	1997-09-16	Oxford University	Multiple particulate antigen delivery system
US5795754A (en) *	1995-07-19	1998-08-18	Merck & Co., Inc.	Synthetic HPV11 virus-like particles
AU770802B2 (en) *	1998-10-21	2004-03-04	Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The	Virus-like particles for the induction of autoantibodies
US20030005410A1 (en) *	1999-06-02	2003-01-02	American Management Systems, Inc. Of Fairfax, Va.	Xml parser for cobol
US20030099668A1 (en) *	2001-09-14	2003-05-29	Cytos Biotechnology Ag	Packaging of immunostimulatory substances into virus-like particles: method of preparation and use

2003
- 2003-09-03 EP EP03808079A patent/EP1549140A4/de not_active Withdrawn
- 2003-09-03 CA CA002497798A patent/CA2497798A1/en not_active Abandoned
- 2003-09-03 AU AU2003296902A patent/AU2003296902A1/en not_active Abandoned
- 2003-09-03 WO PCT/US2003/027563 patent/WO2004032622A2/en not_active Application Discontinuation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991015587A1 (en) *	1990-04-06	1991-10-17	Commonwealth Scientific And Industrial Research Organisation	Self-polymerising expression system based on modified potyvirus coat proteins
WO1995031476A1 (en) *	1994-05-17	1995-11-23	The University Of Queensland	Recombinant papilloma virus l1
WO1996012028A1 (en) *	1994-10-14	1996-04-25	Biosource Technologies, Inc.	Production of peptides in plants as viral coat protein fusions
CA2355883A1 (en) *	1998-12-23	2000-07-06	Merck & Co., Inc.	Neutralizing assay using human papillomavirus virus-like particles
WO2001066778A2 (en) *	2000-03-08	2001-09-13	Large Scale Biology Corporation	Production of foreign polypeptides in plants as viral coat protein fusions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2004032622A2 *

Also Published As

Publication number	Publication date
WO2004032622A2 (en)	2004-04-22
CA2497798A1 (en)	2004-04-22
WO2004032622A3 (en)	2005-04-28
WO2004032622A8 (en)	2007-11-01
EP1549140A2 (de)	2005-07-06
AU2003296902A1 (en)	2004-05-04

Publication	Publication Date	Title
NO2017058I1 (no)	2017-11-10	HPV 58 L1 protein
NO2017012I1 (no)	2017-04-05	HPV 45 L1 protein
MA26314A1 (fr)	2004-10-01	Concentrés de proteines de lait modifiees et leur utilisation dans la fabrication de gels et de produits laitiers
AU2003273213A8 (en)	2003-12-19	Amyloid peptide inactivating enzyme to treat alzheimer's disease
DE69917157D1 (de)	2004-06-17	Körpernahe hohle Prothese
LU91857I2 (fr)	2011-10-24	Abarelix, optionnellement sous forme de sel pharmaceutiquement acceptable
AU2003206413A8 (en)	2003-07-24	Substituted amino carboxamides for the treatment of alzheimer's disease
FR2827170B1 (fr)	2004-07-16	Utilisation de peptides pour augmenter l'adhesion cellulaire
FR2848413B1 (fr)	2005-07-29	Plaque d'osteosynthese pour l'osteosynthese de petits os voisins les uns des autres
AU2002335794A1 (en)	2003-04-22	Allylamides useful in the treatment of alzheimer's disease
AU4550901A (en)	2001-09-17	Production of foreign polypeptides in plants as viral coat protein fusions
AU2002212471A1 (en)	2002-05-15	Peptides for use in the treatment of alzheimer's disease
WO2000037487A8 (de)	2001-03-29	INHIBITOREN DES INTEGRINS αvβ¿6?
EP1549140A4 (de)	2009-04-29	Herstellung von peptiden in pflanzen als virush llproteinfusionen
PL357256A1 (en)	2003-06-02	Ship's hull bowl shape
IL160190A0 (en)	2004-07-25	Use of copolymer to produce a galenic form containining a peptide or a protein as active agent
EP1077600A4 (de)	2003-04-09	Herstellung von biomedizinischen peptiden und proteinen in pflanzen unter verwendung von pflanzlichen virusvektoren
AU2003303141A8 (en)	2004-07-22	Hydroxypropyl amides for the treatment of alzheimer's disease
FR2868263B1 (fr)	2006-12-15	Contenant d'amenee de produit cosmetique en forme de baton
ATE353913T1 (de)	2007-03-15	Neue collectine
DE60114668D1 (de)	2005-12-08	Prozess zur Herstellung des Anti-Migräne Wirkstoffs Eletriptan
FR2842105B1 (fr)	2012-12-28	Localisation des genes impliques dans la canitie precoce
EP1381388A4 (de)	2005-04-13	Herstellung von peptiden in pflanzen als n-terminale proteinfusionen mit virusmantel
JP2003284553A5 (de)	2005-09-02
WO2000006735A8 (en)	2000-04-06	Interferon alpha hybrids

Legal Events

Date	Code	Title	Description
2005-05-20	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2005-07-06	17P	Request for examination filed	Effective date: 20050331
2005-07-06	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
2005-07-06	AX	Request for extension of the european patent	Extension state: AL LT LV MK
2005-11-30	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61K 48/00 A
2005-12-21	DAX	Request for extension of the european patent (deleted)
2007-12-19	R17D	Deferred search report published (corrected)	Effective date: 20071101
2007-12-26	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 39/00 20060101AFI20071122BHEP
2008-07-02	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: KENTUCKY BIOPROCESSING, LLC
2009-04-29	A4	Supplementary search report drawn up and despatched	Effective date: 20090326
2009-04-29	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 39/12 20060101AFI20090320BHEP
2009-10-21	RIC1	Information provided on ipc code assigned before grant	Ipc: A01N 61/00 20060101ALI20090917BHEP Ipc: A61K 38/12 20060101ALI20090917BHEP Ipc: A61K 39/00 20060101AFI20090917BHEP
2010-07-21	17Q	First examination report despatched	Effective date: 20100622
2012-04-10	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2012-05-09	18D	Application deemed to be withdrawn	Effective date: 20111112