EP1290952B1 - Compositions for taking dietary fibers - Google Patents
Compositions for taking dietary fibers Download PDFInfo
- Publication number
- EP1290952B1 EP1290952B1 EP00937218A EP00937218A EP1290952B1 EP 1290952 B1 EP1290952 B1 EP 1290952B1 EP 00937218 A EP00937218 A EP 00937218A EP 00937218 A EP00937218 A EP 00937218A EP 1290952 B1 EP1290952 B1 EP 1290952B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- water
- soluble
- dietary fiber
- composition
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Definitions
- the present invention relates to a composition for taking dietary fibers useful as a food for ameliorating bowel movement.
- dietary fibers are roughly said to be formation of a feces skeleton by water holding ability and a source of energy supply to enteric canals by short-chain fatty acids formed by being used in enterobacteria, and the details and degrees of the functions are not always homogeneous in the respective dietary fibers. Accordingly, it is recommended to take various dietary fibers from various foods. However, it is difficult to take various dietary fibers different in the details and degrees of the functions with good balance in an actual dietary life, and there is a demand for proposal of dietary fiber foods which can effectively support the action of the large bowel.
- T. Kondo et al. investigated the large intestine fermentability of commercial beverages comprising dietary fibers and have found that oligosaccharides produce large amounts of hydrogen and methane in some people (T. Kondo et al., Journal of Gastroenterology 31, 1996, 654-658).
- EP 1 125 507 A suggested the use of an inulin composition consisting of an easily fermentable short-chain inulin component and a hardly fermentable long-chain inulin component for modulating the bacterial flora and the fermentation pattern of inulin in the large intestine.
- US 5 085 883 A concerns the use of a dietary fiber blend comprising water-soluble and hardly water-soluble dietary fibers in a powdered nutritional product.
- the present inventors have paid attention to complete separation of the function of dietary fiber forming the skeleton of feces by the water holding ability from the function of dietary fiber which is fermented by enterobacteria to form short-chain fatty acids which will become an energy source for enteric canals, and water-soluble dietary fibers applicable to the form of drink easy to be taken.
- the water-soluble and hardly fermentable dietary fiber exhibits an effective feces bulk-increasing effect by the water holding ability thereof to impart physical stimulation to the enteric canals
- the water-soluble and fermentable dietary fiber is used by the enterobacteria to form short-chain fatty acids to impart chemical stimulation to the enteric canals, thereby facilitating the peristaltic movement of the enteric canals from both sides to achieve a high ameliorating effect on bowel movement.
- the present invention provides a composition for taking dietary fibers, which comprises 1 to 50% by weight, on the basis of the whole composition, of dietary fibers composed of water-soluble and hardly fermentable dietary fiber and water-soluble and fermentable dietary fiber selected from a group consisting of pectin, depolymerized pectin, guar gum, molecular-weight reduced guar gum, hemicellulose, gum arabic, glucomannan, locust bean gum, pullulan, curdlan, xanthan gum, gellan gum and indigestible dextrin, wherein the water-soluble and fermentable dietary fiber is contained in a proportion of 0.1 to 3 parts by weight per part by weight of the water-soluble and hardly fermentable dietary fiber.
- Examples of the water-soluble and hardly fermentable dietary fiber used in the composition according to the present invention include sodium alginate, depolymerized sodium alginate, carrageenan, fucoidan, laminaran, sodium carboxymethyl cellulose, polydextrose and agar.
- dopolymerized sodium alginate and polydextrose are particularly preferred in that the viscosities of aqueous solutions thereof are low.
- the water-soluble and fermentable dietary fiber include pectin, depolymerized pectin, guar gum, molecular weight-reduced guar gum, hemicellulose, gum arabic, glucomannan, locust bean gum, pullulan, curdlan, xanthan gum, gellan gum and indigestible dextrin.
- depolymerized pectin, depolymerized guar gum, hemicellulose, gum arabic, pullulan and indigestible dextrin are particularly preferred in that the viscosities of aqueous solutions thereof are low.
- hemicellulose may be used those derived from wheat, soybean and corn.
- hemicellulose is hence preferred.
- hemicellulose having a low molecular weight, particularly, adjusted in its average molecular weight to 100,000 or lower is preferred because the viscosity of an aqueous solution thereof is low.
- an enzyme to act on high-molecular weight hemicellulose or subject the high-molecular weight hemicellulose to thermal decomposition or decomposition under pressure in accordance with a method known per se in the art.
- These dietary fibers preferably have a viscosity of 20 mPa ⁇ s or lower in terms of a 5% by weight of an aqueous solution at room temperature when they are used in drink.
- composition according to the present invention contains 1 to 50% by weight, preferably 2 to 20% by weight, particularly preferably 5 to 10% by weight of dietary fibers composed of the water-soluble and hardly fermentable dietary fiber and the water-soluble and fermentable dietary fiber from the viewpoints of an ameliorating effect on bowel movement and an improving effect on intestinal disorder.
- the water-soluble and fermentable dietary fiber is contained in a proportion of 0.1 to 3 parts by weight (preferably 0.3 to 3 parts by weight, particularly preferably 0.5 to 2 parts by weight) per part by weight of the water-soluble and hardly fermentable dietary fiber from the viewpoints of the ameliorating effect on bowel movement and the improving effect on intestinal disorder.
- the short-chain fatty acids formed from the fermentable dietary fiber participate in increase of water content in feces and also contribute to imparting of softness to the feces.
- the proportion of the water-soluble and fermentable dietary fiber to the water-soluble and hardly fermentable dietary fiber exceeds 3 times by weight, the proportion of the short-chain fatty acids formed is increased compared with the water-soluble and hardly fermentable dietary fiber forming the feces skeleton by the water-retaining ability to bring about formation of a loose passage in some cases. It is hence not preferable to contain the water-soluble and fermentable dietary fiber in such a high proportion.
- the form of the composition according to the present invention is such that the dietary fibers can be orally taken, and it can be provided as food such as functional food, health food or snack food, a drug, or the like.
- Examples of the form of food include cookie, flake, wafer, tablets, granules and snack confectionery, and besides drink, with the form of drink being particularly preferred from the viewpoint of easy intake.
- composition according to the present invention in the form of food, other dietary fibers, for example, starch and dextrin; saccharides such as sucrose; proteins such as casein, soybean protein and albumen; minerals such as calcium carbonate and iron lactate; vitamins such as vitamins A, B 1 , B 2 , B 12 and C; and rice, barley, wheat, corn, various kinds of vegetables, meats, edible oils, seasonings, water and the like may be suitably incorporated either singly or in any combination thereof in addition to the 2 dietary fibers.
- saccharides such as sucrose
- proteins such as casein, soybean protein and albumen
- minerals such as calcium carbonate and iron lactate
- vitamins such as vitamins A, B 1 , B 2 , B 12 and C
- rice, barley, wheat, corn, various kinds of vegetables, meats, edible oils, seasonings, water and the like may be suitably incorporated either singly or in any combination thereof in addition to the 2 dietary fibers.
- the amount of the composition according to the present invention to be taken is preferably 1 to 20 g in terms of the amount of the dietary fibers per time (meal).
- Cookies of their corresponding formulations shown in Table 1 were prepared in accordance with a method known per se in the art to be provided as test food.
- a cookie dough before baking is divided into individual cookie portions (each 10 g), and 3 baked products thereof are taken, whereby the following amounts of test dietary fibers required per day to be aimed at can be satisfied.
- non-ingestion period was taken for 7 days, and ingestion period was successively taken for 7 days.
- the conditions of bowel movement during the ingestion period had been taken were compared with the conditions of bowel movement during the non-ingestion period had been taken by the following questionnaire.
- compositions according to the present invention with the water-soluble and hardly fermentable dietary fiber and the water-soluble and fermentable dietary fiber combined in specified proportions is far excellent not only in the improving effect on bowel movement frequency but also in the improving effect on the feeling of displeasure such as full consciousness or feeling of unsatisfied defecation compared with the food incorporating another dietary fiber.
- composition according to the present invention in the form of drink.
- Example 2 Sodium alginate and indigestible dextrin were used in a mixing ratio (1:9) described in Example 2 of Japanese Patent No. 2779616 to prepare a drink similar to that of Example 3 described above.
- Component % by weight
- Depolymerized sodium alginate the same as that used in Example 1
- Indigestible dextrin the same as that used in Example 3
- High fructose syrup from glucose-fructose mixture 5.0 Citric acid 0.1 Grapefruit juice 20.0
- Example 3 The drink according to Example 3 and the drink according to Comparative Example 2 were used to conduct a comparative investigation.
- a drink was prepared according to a formulation shown below.
- the drink (100 mL) is taken, whereby the amounts of dietary fibers required per day to be aimed at can be satisfied.
- Component (% by weight) Depolymerized sodium alginate (the same as that used in Example 1) 4 Depolymerized guar gum (the same as that used in Example 1) 5 Reducing maltose syrup 3 Erythritol 6 Flavor 0.2 Citric acid 0.3 Water Balance 100 (100 mL)
- a drink was prepared according to a formulation shown below.
- the drink (100 mL) is taken, whereby the amounts of dietary fibers required per day to be aimed at can be satisfied.
- compositions according to the present invention incorporate water-soluble and hardly fermentable dietary fiber contributing to the formation of feces skeleton and water-soluble and fermentable dietary fiber fermented by enterobacteria to form short-chain fatty acids which are an energy source mainly for the large bowel are incorporated in combination, not only bowel movement frequency but also full consciousness, feeling of unsatisfied defecation, etc. are remarkably ameliorated.
- the compositions are useful as foods for ameliorating bowel movement.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Non-Alcoholic Beverages (AREA)
Description
(Amounts of test dietary fibers required per days) | |
·Water-soluble and hardly fermentable dietary fiber | 3 g |
·Water-soluble and fermentable dietary fiber | 3 g |
Material | Amount incorporated |
Salt-free butter | 50 g |
Wheat flour (Soft flour) | 50 g |
Water-soluble and hardly fermentable dietary fiber | 25 g |
Water-soluble and fermentable dietary fiber | 25 g |
Sugar (granulated sugar) | 50 g |
Egg (whole egg) | 40 g |
Albumen | 10 g |
Sodium bicarbonate | 1 g |
Ammonium carbonate | 2 g |
(Improved; Increased; Unchanged; Neither increased nor decreased; Deteriorated; Decreased)
(Became better; Improved; Unchanged; Became worse; Deteriorated)
Depolymerized sodium alginate (viscosity of a 5% by weight aqueous solution = about 10 mPa·s)
Depolymerized guar gum (viscosity of a 5% by weight aqueous solution = about 5 mPa·s)
Depolymerized sodium alginate (the same as that used in Example 1)
Hemicellulose (viscosity of a 5% by weight aqueous solution = about 16 mPa·s)
Improving effect on bowel movement frequency | Change in condition of bowels | ||
Comp. Ex. 1 | Case improved | 4/8 persons | 1/8 persons |
Unchanged | 2/8 persons | 4/8 persons | |
Case | 2/8 persons | 3/8 persons | |
deteriorated | |||
Ex. 1 | Case improved | 5/9 persons | 3/9 persons |
Unchanged | 1/9 persons | 6/9 persons | |
Case | 3/9 persons | 0/9 persons | |
deteriorated | |||
Ex. 2 | Case improved | 8/10 persons | 7/10 persons |
Unchanged | 0/10 persons | 2/10 persons | |
Case | 2/10 persons | 1/10 persons | |
deteriorated |
(Component) | (% by weight) |
Depolymerized sodium alginate (the same as that used in Example 1) | 2.5 |
Indigestible dextrin (viscosity of a 5% by weight aqueous solution = about 3 mPa·s) | 2.5 |
high fructose syrup from glucose-fructose mixture | 5.0 |
Citric acid | 0.1 |
Grapefruit juice | 20.0 |
Flavor | 0.1 |
Water | 68.8 |
(Component) | (% by weight) |
Depolymerized sodium alginate (the same as that used in Example 1) | 0.5 |
Indigestible dextrin (the same as that used in Example 3) | 4.5 |
High fructose syrup from glucose-fructose mixture | 5.0 |
Citric acid | 0.1 |
Grapefruit juice | 20.0 |
Flavor | 0.1 |
Water | 68.8 |
Improving effect on bowel movement frequency | Change in condition of bowels | ||
Ex. 2 | Case improved | 8/12 persons | 8/12 persons |
Unchanged | 3/12 persons | 3/12 persons | |
Case | 1/12 persons | 1/12 persons | |
deteriorated | |||
Comp. Ex. 1 | Case improved | 5/11 persons | 4/11 persons |
Unchanged | 6/11 persons | 6/11 persons | |
Case | 0/11 persons | 1/11 persons | |
deteriorated |
(Component) | (% by weight) |
Depolymerized sodium alginate (the same as that used in Example 1) | 4 |
Depolymerized guar gum (the same as that used in Example 1) | 5 |
Reducing maltose syrup | 3 |
Erythritol | 6 |
Flavor | 0.2 |
Citric acid | 0.3 |
Water | Balance |
100 (100 mL) |
(Component) | (% by weight) |
Depolymerized sodium alginate (the same as that used in Example 1) | 4 |
Depolymerized hemicellulose (viscosity of a 5% by weight aqueous solution = about 7 mPa·s) | 5 |
Reducing maltose syrup | 3 |
Erythritol | 6 |
Flavor | 0.2 |
Citric acid | 0.3 |
Water | Balance |
100 (100 mL) |
Claims (5)
- A composition for taking dietary fibers, which comprises 1 to 50 % by weight, on the basis of the whole composition, of dietary fibers composed of water-soluble and hardly fermentable dietary fiber and water-soluble and fermentable dietary fiber selected from a group consisting of pectin, depolymerized pectin, guar gum, molecular-weight reduced guar gum, hemicellulose, gum arabic, glucomgannan, locust bean gum, pullulan, curdlan, xanthan gum, gellan gum and indigestible dextrin, wherein the water-soluble and fermentable dietary fiber is contained in a proportion of 0.1 to 3 parts by weight per part by weight of the water-soluble and hardly fermentable dietary fiber.
- The composition for taking dietary fibers according to claim 1, wherein the viscosities of the water-soluble and hardly fermentable dietary fiber and the water-soluble and fermentable dietary fiber are each 20 mPa·s or lower in terms of a 5% by weight of an aqueous solution at room temperature.
- The composition for taking dietary fibers according to claim 1 or 2, wherein the form of the composition is a food.
- The composition for taking dietary fibers according to any one of claims 1 to 3, wherein the form of the composition is a drink
- The composition for taking dietary fibers according to any one of claims 1 to 4, which is a food for ameliorating bowel movement.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2000/003850 WO2001095746A1 (en) | 2000-06-14 | 2000-06-14 | Compositions for taking dietary fibers |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1290952A1 EP1290952A1 (en) | 2003-03-12 |
EP1290952A4 EP1290952A4 (en) | 2004-03-17 |
EP1290952B1 true EP1290952B1 (en) | 2005-03-30 |
Family
ID=11736147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00937218A Expired - Lifetime EP1290952B1 (en) | 2000-06-14 | 2000-06-14 | Compositions for taking dietary fibers |
Country Status (4)
Country | Link |
---|---|
US (1) | US8187624B1 (en) |
EP (1) | EP1290952B1 (en) |
DE (1) | DE60019171T2 (en) |
WO (1) | WO2001095746A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4945096B2 (en) * | 2004-10-29 | 2012-06-06 | 松谷化学工業株式会社 | Method for producing indigestible dextrin containing isomerized sugar |
JP2007135457A (en) * | 2005-11-17 | 2007-06-07 | Kao Corp | Vegetable juice and/or fruit beverage |
GB2447067A (en) * | 2007-02-20 | 2008-09-03 | Branko R Babic | Alteration of osmotic gradients by polyhydroxy compounds |
FR2991138B1 (en) | 2012-05-31 | 2014-07-04 | Sensis Lab | SOLID FOOD SUPPLEMENT FOR SANDWICH, METHOD OF MANUFACTURE AND SANDWICH COMPRISING SUCH A SOLID SUPPLEMENT |
CN104812244B (en) | 2012-09-17 | 2018-10-30 | 卡莱克汀医疗有限公司 | Enhance the method for specific immunotherapy in treatment of cancer |
ES2954279T3 (en) * | 2016-12-15 | 2023-11-21 | Nestle Sa | Compositions and methods that modulate phosphorus or enzymes in a companion animal |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62220169A (en) | 1986-03-18 | 1987-09-28 | Yakult Honsha Co Ltd | liquid food |
US5126143A (en) * | 1987-04-25 | 1992-06-30 | Terumo Kabushiki Kaisha | Bowel movement-improving food products |
JPH0611764B2 (en) * | 1988-12-07 | 1994-02-16 | 雪印乳業株式会社 | Method for producing water-soluble hemicellulose |
JPH02276556A (en) | 1989-01-24 | 1990-11-13 | Matsutani Kagaku Kogyo Kk | Composition for food containing edible fiber component and food prepared therefrom |
US5622738A (en) * | 1989-05-16 | 1997-04-22 | Nihon Shokuhin Kako Co., Ltd. | Method of preparing water-soluble dietary fiber |
JPH0451840A (en) * | 1990-06-18 | 1992-02-20 | Matsutani Kagaku Kogyo Kk | Production of bakery product containing dietary fiber |
US5085883A (en) | 1991-06-27 | 1992-02-04 | Abbott Laboratories | Blend of dietary fiber for nutritional products |
US5104677A (en) * | 1991-06-27 | 1992-04-14 | Abbott Laboratories | Liquid nutritional product |
DK0552728T3 (en) | 1992-01-20 | 1999-11-15 | Japan Tobacco Inc | Hitherto unknown pectinase |
JPH0712294A (en) | 1993-06-23 | 1995-01-17 | Miyawaki Inc | Automatic diagnosing device for trap |
JPH0965855A (en) | 1995-08-28 | 1997-03-11 | Otsuka Shokuhin Kk | Low-caloric food material for controlling intestinal function |
CA2283573A1 (en) * | 1997-03-13 | 1998-09-17 | Merlin D. Breen | Nutritional formula containing hydrolyzed protein and a fiber blend |
AU8406298A (en) * | 1997-07-16 | 1999-02-10 | Rhodia Inc. | Production of galactomannan products by enzymatic reaction on guar splits |
JP2779616B1 (en) | 1997-09-10 | 1998-07-23 | 株式会社紀文フードケミファ | Dietary fiber-containing composition |
JP3874560B2 (en) | 1998-01-09 | 2007-01-31 | 旭化成ケミカルズ株式会社 | Fine cellulose-containing composite |
JP3243559B2 (en) | 1998-02-18 | 2002-01-07 | 株式会社はくばく | Process for producing water-soluble dietary fiber mainly composed of barley bran-derived β-glucan |
JP4169388B2 (en) | 1998-04-24 | 2008-10-22 | 旭化成ケミカルズ株式会社 | Cellulose composite |
US6004610A (en) * | 1998-06-16 | 1999-12-21 | General Nutrition Corporation | Compositions of dietary fiber rich and low viscosity beverages |
JP3413134B2 (en) | 1998-12-18 | 2003-06-03 | 花王株式会社 | Composition for dietary fiber intake |
EP1125507A1 (en) * | 2000-02-15 | 2001-08-22 | Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.) | Inulin products with improved nutritional properties |
-
2000
- 2000-06-14 DE DE60019171T patent/DE60019171T2/en not_active Expired - Lifetime
- 2000-06-14 EP EP00937218A patent/EP1290952B1/en not_active Expired - Lifetime
- 2000-06-14 WO PCT/JP2000/003850 patent/WO2001095746A1/en active IP Right Grant
- 2000-06-14 US US10/297,582 patent/US8187624B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1290952A1 (en) | 2003-03-12 |
DE60019171D1 (en) | 2005-05-04 |
WO2001095746A1 (en) | 2001-12-20 |
EP1290952A4 (en) | 2004-03-17 |
US8187624B1 (en) | 2012-05-29 |
DE60019171T2 (en) | 2006-02-02 |
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