[go: up one dir, main page]

EP1255998A4 - Molecular impriniting compositions and methods for binding and analyzing macromolecules - Google Patents

Molecular impriniting compositions and methods for binding and analyzing macromolecules

Info

Publication number
EP1255998A4
EP1255998A4 EP01910871A EP01910871A EP1255998A4 EP 1255998 A4 EP1255998 A4 EP 1255998A4 EP 01910871 A EP01910871 A EP 01910871A EP 01910871 A EP01910871 A EP 01910871A EP 1255998 A4 EP1255998 A4 EP 1255998A4
Authority
EP
European Patent Office
Prior art keywords
molecular
compositions
impriniting
binding
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01910871A
Other languages
German (de)
French (fr)
Other versions
EP1255998A1 (en
Inventor
Chin-Shiou Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspira Biosystems Inc
Original Assignee
Aspira Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/507,300 external-priority patent/US6458599B1/en
Application filed by Aspira Biosystems Inc filed Critical Aspira Biosystems Inc
Publication of EP1255998A1 publication Critical patent/EP1255998A1/en
Publication of EP1255998A4 publication Critical patent/EP1255998A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/268Polymers created by use of a template, e.g. molecularly imprinted polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/06Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
    • B01J31/063Polymers comprising a characteristic microstructure
    • B01J31/067Molecularly imprinted polymers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00639Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00664Three-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00677Ex-situ synthesis followed by deposition on the substrate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00Assays involving molecular imprinted polymers/polymers created around a molecular template

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Cosmetics (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Shaping Of Tube Ends By Bending Or Straightening (AREA)
  • Dental Preparations (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Abstract

The present invention provides molecular imprint compositions useful for capturing, isolating, detecting, analyzing and/or quantifying macromolecules in a sample. The molecular imprint compositions comprise a matrix material defining an imprint of a template molecule that corresponds to a portion of a macromolecule.
EP01910871A 2000-02-18 2001-02-16 Molecular impriniting compositions and methods for binding and analyzing macromolecules Withdrawn EP1255998A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US50729900A 2000-02-18 2000-02-18
US507299 2000-02-18
US09/507,300 US6458599B1 (en) 2000-02-18 2000-02-18 Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules
US507300 2000-02-18
US20308200P 2000-05-09 2000-05-09
US203082P 2000-05-09
PCT/US2001/005125 WO2001061355A1 (en) 2000-02-18 2001-02-16 Molecular impriniting compositions and methods for binding and analyzing macromolecules

Publications (2)

Publication Number Publication Date
EP1255998A1 EP1255998A1 (en) 2002-11-13
EP1255998A4 true EP1255998A4 (en) 2006-03-15

Family

ID=27394506

Family Applications (2)

Application Number Title Priority Date Filing Date
EP01910871A Withdrawn EP1255998A4 (en) 2000-02-18 2001-02-16 Molecular impriniting compositions and methods for binding and analyzing macromolecules
EP01912785A Expired - Lifetime EP1261873B1 (en) 2000-02-18 2001-02-16 Compositions and methods for surface imprinting

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP01912785A Expired - Lifetime EP1261873B1 (en) 2000-02-18 2001-02-16 Compositions and methods for surface imprinting

Country Status (9)

Country Link
EP (2) EP1255998A4 (en)
JP (2) JP2003525320A (en)
AT (1) ATE408639T1 (en)
AU (2) AU2001238433A1 (en)
CA (2) CA2398999A1 (en)
DE (1) DE60135831D1 (en)
IL (2) IL151217A0 (en)
NO (1) NO20023811L (en)
WO (2) WO2001061354A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458599B1 (en) 2000-02-18 2002-10-01 Aspira Biosystems, Inc. Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules
US7105289B2 (en) 2001-04-11 2006-09-12 Aspira Biosystems, Inc. Inverse emulsion methods of making polymeric imprint beads
SE0300244D0 (en) * 2003-01-30 2003-01-30 Mip Technologies Ab Forsknings Molecularly imprinted polymers for extraction of components from foodstuffs
WO2004081059A1 (en) * 2003-03-14 2004-09-23 National Institute Of Advanced Industrial Science And Technology Process for producing macromolecule-identifying polymer
AU2005205341B2 (en) * 2004-01-07 2009-11-19 The Research Foundation Of State University Of New York Protein imprinted polymers with integrated emission sites
US9035025B2 (en) 2004-01-30 2015-05-19 Mip Technologies Ab Molecularly imprinted surfaces using surface-bound peptides
JP2006257170A (en) * 2005-03-15 2006-09-28 Hokkaido Univ Method for forming microporous structure and use thereof
JP5021183B2 (en) 2005-05-20 2012-09-05 アークレイ株式会社 Protein immobilization membrane, immobilization method, and biosensor
US20100068820A1 (en) * 2005-06-22 2010-03-18 Adhesives Research, Inc. Molecularly imprinted polymer and use thereof in diagnostic devices
FR2887885B1 (en) 2005-07-04 2007-09-14 Polyintell Sarl MOLECULAR IMPRESSIONS WITH IMPROVED RECONNAISSANCE CAPACITY, PREPARATION METHOD AND USE THEREOF
JP4547324B2 (en) * 2005-11-24 2010-09-22 シャープ株式会社 Protein recognition structure, protein recognition substrate, and production method thereof
JP4925756B2 (en) * 2006-07-19 2012-05-09 シャープ株式会社 Protein recognition structure, protein recognition substrate, and production method thereof
JP4853971B2 (en) * 2007-07-18 2012-01-11 国立大学法人神戸大学 Method for producing sensing chip for target molecule
DK2212020T3 (en) 2007-11-12 2018-10-01 Surecapture Tech Ab EMBROIDERED POLYMERS WITH AFFINITY FOR PHOSHORIORED PEPTIDES AND PROTEINS
JP2008151801A (en) * 2008-01-24 2008-07-03 Toshiba Corp Molecular recognition sensor
JP2008111854A (en) * 2008-01-24 2008-05-15 Toshiba Corp Molecule recognition sensor
JP4724188B2 (en) * 2008-01-24 2011-07-13 株式会社東芝 Molecular recognition sensor
JP5099074B2 (en) * 2009-05-11 2012-12-12 株式会社豊田中央研究所 Adsorption carrier having selective adsorption region of target molecule and method for producing the same
CN101962824A (en) * 2010-09-21 2011-02-02 福建师范大学 Method for preparing printed fibers for efficiently separating naringin in water phase based on electric spinning technology
TWI450961B (en) * 2011-12-16 2014-09-01 Mackay Memorial Hospital A thin film with a fixed phase of C-reactive protein and its application to the susceptor
WO2014178081A2 (en) * 2013-04-30 2014-11-06 Zim Laboratories Limited Molecular traps for certain undesirable materials
CN104075925B (en) * 2014-07-22 2016-08-17 中国科学院烟台海岸带研究所 A kind of preparation method of protein nucleocapsid trace microballoon based on quantum dot
US20170172946A1 (en) * 2015-12-21 2017-06-22 Stephan Hau Micro-solid phase extraction
CN106565915B (en) * 2016-10-25 2018-10-09 江苏大学 A kind of preparation method of the mesoporous imprinted polymer of double temperature sensitive types
CN117165646A (en) * 2023-08-25 2023-12-05 广州菲勒生物科技有限公司 Collagen tripeptide composition and purification method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814223A (en) * 1996-03-20 1998-09-29 Bio-Rad Laboratories, Inc. Selective recognition of solutes in chromatographic media by artificially created affinity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8900130L (en) * 1989-01-16 1990-07-17 Klaus Mosbach THE CONCEPT THAT USING MANUFACTURED ARTIFICIAL ANTIBODIES BY MOLECULE IMPRESSION METHOD BY IMPRINTING ANY ANTIGEN AND BY MANUFACTUREING ARTIFIED ENTYZYMES BY IMPRINTING
US5310648A (en) * 1991-02-01 1994-05-10 California Institute Of Technology Composition of matter comprising an imprinted matrix exhibiting selective binding interactions through chelated metals
US5587273A (en) * 1993-01-21 1996-12-24 Advanced Microbotics Corporation Molecularly imprinted materials, method for their preparation and devices employing such materials
ATE246212T1 (en) * 1995-05-26 2003-08-15 Igen Inc MOLECULAR-IMBUILT PEARL POLYMERS AND STABILIZED SUSPENSION POLYMERIZATION OF THESE IN PERFLUOROCARBON LIQUIDS
US6057377A (en) * 1998-10-30 2000-05-02 Sandia Corporation Molecular receptors in metal oxide sol-gel materials prepared via molecular imprinting

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814223A (en) * 1996-03-20 1998-09-29 Bio-Rad Laboratories, Inc. Selective recognition of solutes in chromatographic media by artificially created affinity

Also Published As

Publication number Publication date
IL151218A0 (en) 2003-04-10
ATE408639T1 (en) 2008-10-15
IL151217A0 (en) 2003-04-10
CA2395187A1 (en) 2001-08-23
CA2398999A1 (en) 2001-08-23
JP2003525320A (en) 2003-08-26
EP1261873B1 (en) 2008-09-17
DE60135831D1 (en) 2008-10-30
NO20023811D0 (en) 2002-08-12
WO2001061354A1 (en) 2001-08-23
WO2001061355A1 (en) 2001-08-23
NO20023811L (en) 2002-10-14
EP1255998A1 (en) 2002-11-13
EP1261873A4 (en) 2006-03-15
AU2001241531A1 (en) 2001-08-27
EP1261873A1 (en) 2002-12-04
JP2003529634A (en) 2003-10-07
AU2001238433A1 (en) 2001-08-27

Similar Documents

Publication Publication Date Title
EP1255998A4 (en) Molecular impriniting compositions and methods for binding and analyzing macromolecules
DE69735445D1 (en) NON-VOLATILE, NON-VOLATILE MOLECULES FOR MASS MARKING
ATE490466T1 (en) MARKED CELLS USED AS INTERNAL FUNCTIONAL CONTROL IN TESTS FOR DETECTING RARE CELLS
MX336070B (en) Glyphosate tolerant alfalfa events and methods for detection thereof.
AU3541401A (en) Methods and kits for identifying elite event gat-zm1 in biological samples
WO2003073817A3 (en) Rapid and sensitive detection of cells and viruses
WO2005111212A3 (en) Biological bar code
WO2007076128A3 (en) Nanoreporters and methods of manufacturing and use thereof
MXPA05005945A (en) Bentgrass event asr-368 and compositions and methods for detection thereof.
MXPA01010640A (en) Measurement and use of molecular interactions.
ATE483825T1 (en) COMPOSITIONS FOR IDENTIFYING ADENOVIRUSES
DE60142048D1 (en) UNIVERSAL COLLECTION MEDIUM
AU2001262709A1 (en) Method for measuring fluorescence, apparatus for measuring fluorescence and apparatus for evaluating sample using it
WO2004074310A3 (en) Mycobacterial diagnostics
WO2004033631A8 (en) Nucleic acid and polypeptide sequences from lawsonia intracellularis and methods of using
AU1929199A (en) Methods for the recovery and measurement of troponin complexes
WO2004055491A3 (en) Novel method for sequence determination using nmr
EP1604203A4 (en) Methods for direct detection of individual methotrexate metabolites
WO2004094675A3 (en) Compositions and methods for determining the presence of sars coronavirus in a sample
WO2003106649A3 (en) Assay conjugate and uses thereof
EP1730276B8 (en) Method, chip, device and system for extraction of biological materials
WO2000068424A3 (en) Means for detecting and treating pathologies linked to fgfr3
ATE489635T1 (en) APPARATUS, METHOD AND USE FOR TREATING SAMPLES
BR0014626A (en) Leptin analysis
WO2004081531A3 (en) Ligand analysis

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020711

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20060201

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/543 20060101ALI20060126BHEP

Ipc: C08J 3/075 20060101ALI20060126BHEP

Ipc: G01N 33/545 20060101ALI20060126BHEP

Ipc: G01N 33/566 20060101AFI20010829BHEP

17Q First examination report despatched

Effective date: 20060915

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20081114