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EP1157038A4 - Cloning of a p2y-like 7tm receptor (axor17) - Google Patents

Cloning of a p2y-like 7tm receptor (axor17)

Info

Publication number
EP1157038A4
EP1157038A4 EP00908675A EP00908675A EP1157038A4 EP 1157038 A4 EP1157038 A4 EP 1157038A4 EP 00908675 A EP00908675 A EP 00908675A EP 00908675 A EP00908675 A EP 00908675A EP 1157038 A4 EP1157038 A4 EP 1157038A4
Authority
EP
European Patent Office
Prior art keywords
axor17
cloning
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00908675A
Other languages
German (de)
French (fr)
Other versions
EP1157038A1 (en
Inventor
Nabil Elshourbagy
Usman Shabon
David Michalovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9904562.7A external-priority patent/GB9904562D0/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1157038A1 publication Critical patent/EP1157038A1/en
Publication of EP1157038A4 publication Critical patent/EP1157038A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP00908675A 1999-02-26 2000-02-16 Cloning of a p2y-like 7tm receptor (axor17) Withdrawn EP1157038A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9904562.7A GB9904562D0 (en) 1999-02-26 1999-02-26 Novel compounds
GB9904562 1999-02-26
US30238999A 1999-04-30 1999-04-30
US302389 1999-04-30
PCT/US2000/003951 WO2000050458A1 (en) 1999-02-26 2000-02-16 Cloning of a p2y-like 7tm receptor (axor17)

Publications (2)

Publication Number Publication Date
EP1157038A1 EP1157038A1 (en) 2001-11-28
EP1157038A4 true EP1157038A4 (en) 2005-01-19

Family

ID=26315191

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00908675A Withdrawn EP1157038A4 (en) 1999-02-26 2000-02-16 Cloning of a p2y-like 7tm receptor (axor17)

Country Status (2)

Country Link
EP (1) EP1157038A4 (en)
WO (1) WO2000050458A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
WO2001077326A1 (en) * 2000-04-12 2001-10-18 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
CA2408134A1 (en) * 2000-05-18 2001-11-22 Incyte Genomics, Inc. G-protein coupled receptors
AUPR201500A0 (en) 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
ES2383712T3 (en) 2001-01-17 2012-06-25 Biosceptre International Limited Diagnosis and treatment of cancers and other conditions
WO2003021262A1 (en) * 2001-08-28 2003-03-13 Takeda Chemical Industries, Ltd. Screening method
TW200304493A (en) * 2001-12-20 2003-10-01 Aventis Pharma Inc A novel G protein-coupled receptor, GAVE7
WO2004060282A2 (en) * 2002-12-19 2004-07-22 Synaptic Pharmaceutical Corporation Uses of the snorf207 receptor
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
US20060275285A1 (en) * 2005-04-28 2006-12-07 Amgen Inc. Methods of inhibiting a GPCR
AU2007306924A1 (en) 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomas producing antibodies against non functional P2X7 receptor
ES2619681T3 (en) 2007-09-14 2017-06-26 Biosceptre (Aust) Pty Ltd Novel epitopes P2X7
ATE542139T1 (en) 2007-09-14 2012-02-15 Biosceptre Int Ltd PURINERGIC (P2X) RECEPTORS IN EXTRACELLULAR BODY FLUID
CA2729868C (en) 2008-07-04 2018-07-10 Biosceptre International Limited Anti- p2x7 peptides and epitopes
JP5936067B2 (en) 2009-08-20 2016-06-15 バイオセプター・（オーストラリア）・ピーティーワイ・リミテッド Anti-P2X7 receptor antibody and fragment thereof
CN102762595B (en) 2009-12-24 2016-03-02 生物权威国际有限公司 For the oligomeric P2X of non-functional 7the antibody of acceptor
AU2011301153B2 (en) 2010-09-10 2014-11-27 Biosceptre International Limited Companion animal treatments
CA2840251C (en) 2011-07-01 2023-09-12 Biosceptre International Limited Combination therapy of diseases that are associated with non-functional p2x7 receptor expression

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023588A2 (en) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
DE19930285A1 (en) * 1999-07-02 2001-01-04 Michael Brues Human P2YLi gene coding for a putative G protein coupled receptor used to develop new drugs and technologies and to evaluate existing drugs
WO2001002563A2 (en) * 1999-07-02 2001-01-11 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
WO2001004292A1 (en) * 1999-07-13 2001-01-18 Merck Patent Gmbh G-protein coupled receptor and dna sequences thereof
EP1090926A1 (en) * 1999-10-08 2001-04-11 Pfizer Limited Human G-protein coupled receptor
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
WO2001042288A2 (en) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. G-protein coupled receptors
WO2001048189A1 (en) * 1999-12-28 2001-07-05 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and use of the same
WO2001055302A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001057188A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
GB2360523A (en) * 2000-01-25 2001-09-26 Glaxo Group Ltd A purinergic receptor polypeptide, nucleic acid and its medical uses

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023588A2 (en) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
DE19930285A1 (en) * 1999-07-02 2001-01-04 Michael Brues Human P2YLi gene coding for a putative G protein coupled receptor used to develop new drugs and technologies and to evaluate existing drugs
WO2001002563A2 (en) * 1999-07-02 2001-01-11 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
WO2001004292A1 (en) * 1999-07-13 2001-01-18 Merck Patent Gmbh G-protein coupled receptor and dna sequences thereof
EP1090926A1 (en) * 1999-10-08 2001-04-11 Pfizer Limited Human G-protein coupled receptor
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
WO2001042288A2 (en) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. G-protein coupled receptors
WO2001048189A1 (en) * 1999-12-28 2001-07-05 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and use of the same
GB2360523A (en) * 2000-01-25 2001-09-26 Glaxo Group Ltd A purinergic receptor polypeptide, nucleic acid and its medical uses
WO2001055302A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001057188A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 November 1997 (1997-11-01), BOHM, S.K. ET AL.: "P2Y purinoceptor 9 (P2Y9) (Purinergic receptor 9) (G protein-coupled receptor GPR23) (P2Y5-like receptor)", XP002307201, Database accession no. Q99677 *
DATABASE EMBL 11 January 2002 (2002-01-11), XP002307206, Database accession no. ABA08978 *
DATABASE EMBL 12 March 1999 (1999-03-12), OTTENWAELDER, B. ET AL.: "Homo sapiens mRNA, EST DKFZp434B0620_s1 (from clone DKFZp434B0620)", XP002307202, Database accession no. AL042117 *
DATABASE EMBL 17 December 2001 (2001-12-17), XP002307205, Database accession no. AAS39803 *
DATABASE EMBL 21 September 2001 (2001-09-21), XP002307203, Database accession no. AAG64291 *
DATABASE EMBL 21 September 2001 (2001-09-21), XP002307204, Database accession no. AAH49504 *
DATABASE WPI Derwent World Patents Index; AN 2001-425663, XP002307207 *
LEE, D.K. ET AL.: "Discovery and mapping of ten novel G protein-coupled receptor genes", GENE, vol. 275, no. 1, 5 September 2001 (2001-09-05), pages 83 - 91, XP004307114 *
See also references of WO0050458A1 *

Also Published As

Publication number Publication date
WO2000050458A1 (en) 2000-08-31
EP1157038A1 (en) 2001-11-28

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