EP1105528A4 - A novel method of diagnosing, monitoring, staging, imaging and treating breast cancer - Google Patents
A novel method of diagnosing, monitoring, staging, imaging and treating breast cancerInfo
- Publication number
- EP1105528A4 EP1105528A4 EP99935898A EP99935898A EP1105528A4 EP 1105528 A4 EP1105528 A4 EP 1105528A4 EP 99935898 A EP99935898 A EP 99935898A EP 99935898 A EP99935898 A EP 99935898A EP 1105528 A4 EP1105528 A4 EP 1105528A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- staging
- diagnosing
- imaging
- monitoring
- breast cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010006187 Breast cancer Diseases 0.000 title 1
- 208000026310 Breast neoplasm Diseases 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000012544 monitoring process Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- General Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9523298P | 1998-08-04 | 1998-08-04 | |
PCT/US1999/016811 WO2000008210A1 (en) | 1998-08-04 | 1999-07-22 | A novel method of diagnosing, monitoring, staging, imaging and treating breast cancer |
US95232P | 2008-09-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1105528A1 EP1105528A1 (en) | 2001-06-13 |
EP1105528A4 true EP1105528A4 (en) | 2002-09-04 |
Family
ID=22250828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99935898A Withdrawn EP1105528A4 (en) | 1998-08-04 | 1999-07-22 | A novel method of diagnosing, monitoring, staging, imaging and treating breast cancer |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1105528A4 (en) |
JP (1) | JP3422776B2 (en) |
CA (1) | CA2347906A1 (en) |
WO (1) | WO2000008210A1 (en) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6730477B1 (en) | 1998-08-04 | 2004-05-04 | Diadexus, Inc. | Method of diagnosing, monitoring and staging breast cancer |
US6737040B1 (en) | 1998-08-04 | 2004-05-18 | Diadexus, Inc. | Method and antibody for imaging breast cancer |
EP1115426B1 (en) * | 1998-09-23 | 2006-05-31 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating gynecologic cancers |
EP1728518A1 (en) * | 1998-09-23 | 2006-12-06 | Diadexus, Inc. | Method of diagnosing monitoring, staging, imaging and treating gynecologic cancers and testicular cancer |
US6528054B1 (en) | 1998-12-28 | 2003-03-04 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
US6958361B2 (en) | 1998-12-28 | 2005-10-25 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
US6680197B2 (en) | 1998-12-28 | 2004-01-20 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
US6586572B2 (en) | 1998-12-28 | 2003-07-01 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
US6590076B1 (en) | 1999-04-02 | 2003-07-08 | Corixa Corporation | Compositions for the treatment and diagnosis of breast cancer and methods for their use |
US6518237B1 (en) | 1998-12-28 | 2003-02-11 | Corixa Corporation | Compositions for treatment and diagnosis of breast cancer and methods for their use |
US6844325B2 (en) | 1998-12-28 | 2005-01-18 | Corixa Corporation | Compositions for the treatment and diagnosis of breast cancer and methods for their use |
US6969518B2 (en) | 1998-12-28 | 2005-11-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
US7598226B2 (en) | 1998-12-28 | 2009-10-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
US6573368B2 (en) | 1998-12-28 | 2003-06-03 | Corixa Corporation | Compositions for the treatment and diagnosis of breast cancer and methods for their use |
US6762020B1 (en) | 1999-03-15 | 2004-07-13 | Protein Design Labs, Inc. | Methods of diagnosing breast cancer |
US20040141983A1 (en) | 1999-03-15 | 2004-07-22 | Protein Design Labs, Inc. | Compositions against cancer antigen LIV-1 and uses thereof |
US6316272B1 (en) | 1999-03-15 | 2001-11-13 | Eos Biotechnology, Inc. | Methods of diagnosis of colorectal cancer and methods of screening for colorectal cancer modulators |
US6649342B1 (en) | 1999-03-15 | 2003-11-18 | Eos Biotechnology, Inc. | Methods of diagnosing breast cancer, compositions, and methods of screening for breast cancer modulators |
CA2368152A1 (en) * | 1999-03-15 | 2000-09-21 | Eos Biotechnology, Inc. | Novel methods of diagnosing and treating breast cancer, compositions, and methods of screening for breast cancer modulators |
CA2390802A1 (en) * | 1999-11-23 | 2001-05-31 | Diadexus, Inc. | A novel method of diagnosing, monitoring, staging, imaging and treating breast cancer |
US6780586B1 (en) | 1999-11-29 | 2004-08-24 | Protein Design Labs, Inc. | Methods of diagnosing breast cancer |
EP1248800A2 (en) | 1999-11-30 | 2002-10-16 | Corixa Corporation | Compositions and methods for therapy and diagnosis of breast cancer |
US6566502B1 (en) | 2000-01-28 | 2003-05-20 | Eos Biotechnology, Inc. | Methods of diagnosing cancer, compositions, and methods of screening for cancer modulators |
EP1158001B1 (en) * | 2000-05-26 | 2007-11-14 | F. Hoffmann-La Roche Ag | A nucleic acid which is upregulated in human tumor cells, a protein encoded thereby and a process for tumor diagnosis |
US20020146371A1 (en) * | 2000-10-18 | 2002-10-10 | Li King Chuen | Methods for development and use of diagnostic and therapeutic agents |
US20020132255A1 (en) * | 2000-11-20 | 2002-09-19 | Susana Salceda | Compositions and methods relating to breast specific genes and proteins |
EP1407015A2 (en) | 2000-11-22 | 2004-04-14 | Diadexus, Inc. | Compositions and methods relating to breast specific genes and proteins |
WO2004067564A2 (en) | 2003-01-29 | 2004-08-12 | Protein Design Labs, Inc. | Compositions against cancer antigen liv-1 and uses thereof |
US20070208514A1 (en) * | 2003-04-23 | 2007-09-06 | Hiroshi Yatsuhashi | Method of Preparing Disease Prognosis Model, Disease Prognosis Prediction Method using this Model, Prognosis Prediction Device Based on this Model, and Program for Performing the Device and Storage Medium Wherein Said Program is Stored |
GB0320648D0 (en) * | 2003-09-03 | 2003-10-01 | Randox Lab Ltd | Molecular marker |
US20050186610A1 (en) | 2004-02-20 | 2005-08-25 | Yeon-Su Lee | Breast cancer related protein, gene encoding the same, and method of diagnosing breast cancer using the protein and gene |
HUE031726T2 (en) | 2010-12-06 | 2017-07-28 | Seattle Genetics Inc | Humanized antibodies and anti-cancer antibodies against LIV-1 antibodies |
WO2012142670A1 (en) * | 2011-04-20 | 2012-10-26 | The University Of Queensland | Nuclear magnetic resonance agent |
MA45324A (en) | 2016-03-15 | 2019-01-23 | Seattle Genetics Inc | POLYTHERAPY USING ADC-LIV1 AND CHEMOTHERAPEUTIC AGENT |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999002559A1 (en) * | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668267A (en) * | 1995-05-31 | 1997-09-16 | Washington University | Polynucleotides encoding mammaglobin, a mammary-specific breast cancer protein |
US5759776A (en) * | 1995-06-05 | 1998-06-02 | California Pacific Medical Center | Targets for breast cancer diagnosis and treatment |
WO1998018945A1 (en) * | 1996-10-31 | 1998-05-07 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
-
1999
- 1999-07-22 WO PCT/US1999/016811 patent/WO2000008210A1/en not_active Application Discontinuation
- 1999-07-22 CA CA002347906A patent/CA2347906A1/en not_active Abandoned
- 1999-07-22 EP EP99935898A patent/EP1105528A4/en not_active Withdrawn
- 1999-07-22 JP JP2000563832A patent/JP3422776B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999002559A1 (en) * | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
Non-Patent Citations (3)
Title |
---|
DATABASE EMBL [online] ebi; 12 July 1995 (1995-07-12), HILLIER ET AL.: "The WashU-Merck EST project", XP002205120, Database accession no. h26328 * |
DATABASE EMBL [online] ebi; 6 August 1995 (1995-08-06), HILLIER ET AL.: "The WashU-Merck EST project", XP002205119, Database accession no. r83119 * |
See also references of WO0008210A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP3422776B2 (en) | 2003-06-30 |
EP1105528A1 (en) | 2001-06-13 |
JP2002522751A (en) | 2002-07-23 |
CA2347906A1 (en) | 2000-02-17 |
WO2000008210A1 (en) | 2000-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20010305 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: DIADEXUS, INC. |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 12Q 1/68 A, 7C 12P 19/34 B, 7C 07H 21/04 B, 7G 01N 33/53 B, 7G 01N 33/574 B, 7C 07K 14/47 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20020718 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20020723 |
|
17Q | First examination report despatched |
Effective date: 20040308 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20051116 |